-
1
-
-
0032575688
-
The Bcl-2 protein family: Arbiters of cell survival
-
Adams, J. M., and Cory, S. The Bcl-2 protein family: arbiters of cell survival. Science (Wash. DC), 281: 1322-1326, 1998. (Pubitemid 28406819)
-
(1998)
Science
, vol.281
, Issue.5381
, pp. 1322-1326
-
-
Adams, J.M.1
Cory, S.2
-
2
-
-
0032540453
-
Matters of life and death: Programmed cell death at cold spring harbor
-
DOI 10.1016/S0304-419X(98)00003-1, PII S0304419X98000031
-
Cory, S., and Adams, J. M. Matters of life and death: programmed cell death at Cold Spring Harbor. Biochim. Biophys. Acta, 1377: R25-R44, 1998. (Pubitemid 28207052)
-
(1998)
Biochimica et Biophysica Acta - Reviews on Cancer
, vol.1377
, Issue.2
-
-
Cory, S.1
Adams, J.M.2
-
3
-
-
0032877668
-
Dysregulation of apoptosis in cancer
-
Reed, J. C. Dysregulation of apoptosis in cancer. J. Clin. Oncol., 17: 2941-2953, 1999. (Pubitemid 29415256)
-
(1999)
Journal of Clinical Oncology
, vol.17
, Issue.9
, pp. 2941-2953
-
-
Reed, J.C.1
-
4
-
-
0034898772
-
Bcl-2 antisense oligonucleotides enhance the cytotoxicity of chlorambucil in B-cell chronic lymphocytic leukaemia cells
-
Pepper, C., Hooper, K., Thomas, A., Hoy, T., and Bentley, P. Bcl-2 antisense oligonucleotides enhance the cytotoxicity of chlorambucil in B-cell chronic lymphocytic leukaemia cells. Leuk. Lymphoma, 42: 491-498, 2001. (Pubitemid 32725605)
-
(2001)
Leukemia and Lymphoma
, vol.42
, Issue.3
, pp. 491-498
-
-
Pepper, C.1
Hooper, K.2
Thomas, A.3
Hoy, T.4
Bentley, P.5
-
5
-
-
0034691130
-
Structure-based discovery of an organic compound that binds Bcl-2 protein and induces apoptosis of tumor cells
-
DOI 10.1073/pnas.97.13.7124
-
Wang, J. L., Liu, D., Zhang, Z. J., Shan, S., Han, X., Srinivasula, S. M., Croce, C. M., Alnemri, E. S., and Huang, Z. Structure-based discovery of an organic compound that binds Bcl-2 protein and induces apoptosis of tumor cells. Proc. Natl. Acad. Sci. USA, 97: 7124-7129, 2000. (Pubitemid 30431428)
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, Issue.13
, pp. 7124-7129
-
-
Wang, J.-L.1
Liu, D.2
Zhang, Z.-J.3
Shan, S.4
Han, X.5
Srinivasula, S.M.6
Croce, C.M.7
Alnemri, E.S.8
Huang, Z.9
-
6
-
-
0035150803
-
L
-
DOI 10.1038/35055085
-
Degterev, A., Lugovskoy, A., Cardone, M., Mulley, B., Wagner, G., Mitchison, T., and Yuan, J. Identification of small-molecule inhibitors of interaction between the BH3 domain and Bcl-xL. Nat. Cell Biol., 3: 173-182, 2001. (Pubitemid 32118371)
-
(2001)
Nature Cell Biology
, vol.3
, Issue.2
, pp. 173-182
-
-
Degterev, A.1
Lugovskoy, A.2
Cardone, M.3
Mulley, B.4
Wagner, G.5
Mitchison, T.6
Yuan, J.7
-
7
-
-
0035147650
-
Antimycin A mimics a cell-death-inducing Bcl-2 homology domain 3
-
DOI 10.1038/35055095
-
Tzung, S. P., Kim, K. M., Basanez, G., Giedt, C. D., Simon, J., Zimmerberg, J., Zhang, K. Y., and Hockenbery, D. M. Antimycin A mimics a cell-death-inducing Bcl-2 homology domain 3. Nat. Cell Biol., 3: 183-191, 2001. (Pubitemid 32118372)
-
(2001)
Nature Cell Biology
, vol.3
, Issue.2
, pp. 183-191
-
-
Tzung, S.-P.1
Kim, K.M.2
Basaez, G.3
Giedt, C.D.4
Simon, J.5
Zimmerberg, J.6
Zhang, K.Y.J.7
Hockenbery, D.M.8
-
8
-
-
0030822420
-
Crystal structure of rat Bcl-x(L): Implications for the function of the Bcl-2 protein family
-
DOI 10.1074/jbc.272.44.27886
-
Aritomi, M., Kunishima, N., Inohara, N., Ishibashi, Y., Ohta, S., and Morikawa, K. Crystal structure of rat Bcl-xL. Implications for the function of the Bcl-2 protein family. J. Biol. Chem., 272: 27886-27892, 1997. (Pubitemid 27473591)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.44
, pp. 27886-27892
-
-
Aritomi, M.1
Kunishima, N.2
Inohara, N.3
Ishibashi, Y.4
Ohta, S.5
Morikawa, K.6
-
9
-
-
0033258120
-
Bcl-2 proteins: Regulators of apoptosis or of mitochondrial homeostasis?
-
Vander Heiden, M. G., and Thompson, C. B. Bcl-2 proteins: regulators of apoptosis or of mitochondrial homeostasis? Nat. Cell Biol., 1: E209-E216, 1999. (Pubitemid 129503663)
-
(1999)
Nature Cell Biology
, vol.1
, Issue.8
-
-
Vander, H.M.G.1
Thompson, C.B.2
-
10
-
-
0031451871
-
Targeted disruption of the peripheral-type benzodiazepine receptor gene inhibits steroidogenesis in the R2C leydig tumor cell line
-
DOI 10.1074/jbc.272.51.32129
-
Papadopoulos, V., Amri, H., Li, H., Boujrad, N., Vidic, B., and Garnier, M. Targeted disruption of the peripheral-type benzodiazepine receptor gene inhibits steroidogenesis in the R2C Leydig tumor cell line. J. Biol. Chem., 272: 32129-32135, 1997. (Pubitemid 28011885)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.51
, pp. 32129-32135
-
-
Papadopoulos, V.1
Amri, H.2
Li, H.3
Boujrad, N.4
Vidic, B.5
Garnier, M.6
-
11
-
-
0033558247
-
Peripheral-type benzodiazepine receptor (PBR) in human breast cancer: Correlation of breast cancer cell aggressive phenotype with PBR expression, nuclear localization, and PBR-mediated cell proliferation and nuclear transport of cholesterol
-
Hardwick, M., Fertikh, D., Culty, M., Li, H., Vidic, B., and Papadopoulos, V. Peripheral-type benzodiazepine receptor (PBR) in human breast cancer: correlation of breast cancer cell aggressive phenotype with PBR expression, nuclear localization, and PBR-mediated cell proliferation and nuclear transport of cholesterol. Cancer Res., 59: 831-842, 1999. (Pubitemid 29086736)
-
(1999)
Cancer Research
, vol.59
, Issue.4
, pp. 831-842
-
-
Hardwick, M.1
Fertikh, D.2
Culty, M.3
Li, H.4
Vidic, B.5
Papadopoulos, V.6
-
12
-
-
0033569593
-
Increased expression of peripheral benzodiazepine receptors and diazepam binding inhibitor in human tumors sited in the liver
-
DOI 10.1016/S0024-3205(99)00487-7, PII S0024320599004877
-
Venturini, I., Alho, H., Podkletnova, I., Corsi, L., Rybnikova, E., Pellicci, R., Baraldi, M., Pelto-Huikko, M., Helen, P., and Zeneroli, M. L. Increased expression of peripheral benzodiazepine receptors and diazepam binding inhibitor in human tumors sited in the liver. Life Sci., 65: 2223-2231, 1999. (Pubitemid 29524872)
-
(1999)
Life Sciences
, vol.65
, Issue.21
, pp. 2223-2231
-
-
Venturini, I.1
Alho, H.2
Podkletnova, I.3
Corsi, L.4
Rybnikova, E.5
Pellicci, R.6
Baraldi, M.7
Pelto-Huikko, M.8
Helen, P.9
Zeneroli, M.L.10
-
13
-
-
0033065614
-
Benzodiazepine receptor agonists modulate thymocyte apoptosis through reduction of the mitochondrial transmembrane potential
-
DOI 10.1254/jjp.79.177
-
Tanimoto, Y., Onishi, Y., Sato, Y., and Kizaki, H. Benzodiazepine receptor agonists modulate thymocyte apoptosis through reduction of the mitochondrial transmembrane potential. Jpn. J. Pharmacol., 79: 177-183, 1999. (Pubitemid 29140007)
-
(1999)
Japanese Journal of Pharmacology
, vol.79
, Issue.2
, pp. 177-183
-
-
Tanimoto, Y.1
Onishi, Y.2
Sato, Y.3
Kizaki, H.4
-
14
-
-
0032526746
-
PK11195, a ligand of the mitochondrial benzodiazepine receptor, facilitates the induction of apoptosis and reverses Bcl-2-mediated cytoprotection
-
DOI 10.1006/excr.1998.4084
-
Hirsch, T., Decaudin, D., Susin, S. A., Marchetti, P., Larochette, N., Resche-Rigon, M., and Kroemer, G. PK11195, a ligand of the mitochondrial benzodiazepine receptor, facilitates the induction of apoptosis and reverses Bcl-2-mediated cytoprotection. Exp. Cell Res., 241: 426-434, 1998. (Pubitemid 28366568)
-
(1998)
Experimental Cell Research
, vol.241
, Issue.2
, pp. 426-434
-
-
Hirsch, T.1
Decaudin, D.2
Susin, S.A.3
Marchetti, P.4
Larochette, N.5
Resche-Rigon, M.6
Kroemer, G.7
-
15
-
-
0028859541
-
Bax-deficient mice with lymphoid hyperplasia and male germ cell death
-
Wash. DC
-
Knudson, C. M., Tung, K. S., Tourtellotte, W. G., Brown, G. A., and Korsmeyer, S. J. Bax-deficient mice with lymphoid hyperplasia and male germ cell death. Science (Wash. DC), 270: 96-99, 1995.
-
(1995)
Science
, vol.270
, pp. 96-99
-
-
Knudson, C.M.1
Tung, K.S.2
Tourtellotte, W.G.3
Brown, G.A.4
Korsmeyer, S.J.5
-
16
-
-
0021061819
-
Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
-
Mosmann, T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Methods, 65: 55-63, 1983. (Pubitemid 14203433)
-
(1983)
Journal of Immunological Methods
, vol.65
, Issue.1-2
, pp. 55-63
-
-
Mosmann, T.1
-
17
-
-
4243748749
-
Induction of apoptosis in AML by HA14-1, a cell permeable organic compound identified by protein structure-based computer screening that binds the BH1 to BH3 surface pocket of Bcl-2
-
Andreeff, M., Leysath, C., Konopleva, M., and Hwang, Z. Induction of apoptosis in AML by HA14-1, a cell permeable organic compound identified by protein structure-based computer screening that binds the BH1 to BH3 surface pocket of Bcl-2. Blood, 96: 502a, 2000.
-
(2000)
Blood
, vol.96
-
-
Andreeff, M.1
Leysath, C.2
Konopleva, M.3
Hwang, Z.4
-
18
-
-
0032575750
-
Caspases: Enemies within
-
Thornberry, N. A., and Lazebnik, Y. Caspases: enemies within. Science (Wash. DC), 281: 1312-1316, 1998. (Pubitemid 28406817)
-
(1998)
Science
, vol.281
, Issue.5381
, pp. 1312-1316
-
-
Thornberry, N.A.1
Lazebnik, Y.2
-
19
-
-
0031958511
-
+ deprivation
-
D'Mello, S. R., Aglieco, F., Roberts, M. R., Borodezt, K., and Haycock, J. W. A DEVD-inhibited caspase other than CPP32 is involved in the commitment of cerebellar granule neurons to apoptosis induced by K+ deprivation. J. Neurochem., 70: 1809-1818, 1998. (Pubitemid 28207802)
-
(1998)
Journal of Neurochemistry
, vol.70
, Issue.5
, pp. 1809-1818
-
-
D'Mello, S.R.1
Aglieco, F.2
Roberts, M.R.3
Borodezt, K.4
Haycock, J.W.5
-
20
-
-
0036131886
-
PK11195, a peripheral benzodiazepine receptor ligand, chemosensitizes acute myeloid leukemia cells to relevant therapeutic agents by more than one mechanism
-
DOI 10.1016/S0145-2126(01)00112-6, PII S0145212601001126
-
Banker, D. E., Cooper, J. J., Fennell, D. A., Willman, C. L., Appelbaum, F. R., and Cotter, F. E. PK11195, a peripheral benzodiazepine receptor ligand, chemosensitizes acute myeloid leukemia cells to relevant therapeutic agents by more than one mechanism. Leuk. Res., 26: 91-106, 2002. (Pubitemid 33085505)
-
(2002)
Leukemia Research
, vol.26
, Issue.1
, pp. 91-106
-
-
Banker, D.E.1
Cooper, J.J.2
Fennell, D.A.3
Willman, C.L.4
Appelbaum, F.R.5
Cotter, F.E.6
-
21
-
-
0032531940
-
Antiproliferative and differentiating effects of benzodiazepine receptor ligands on B16 melanoma cells
-
DOI 10.1016/S0006-2952(98)00149-X, PII S000629529800149X
-
Landau, M., Weizman, A., Zoref-Shani, E., Beery, E., Wasseman, L., Landau, O., Gavish, M., Brenner, S., and Nordenberg, J. Antiproliferative and differentiating effects of benzodiazepine receptor ligands on B16 melanoma cells. Biochem. Pharmacol., 56: 1029-1034, 1998. (Pubitemid 28454568)
-
(1998)
Biochemical Pharmacology
, vol.56
, Issue.8
, pp. 1029-1034
-
-
Landau, M.1
Weizman, A.2
Zoref-Shani, E.3
Beery, E.4
Wasseman, L.5
Landau, O.6
Gavish, M.7
Brenner, S.8
Nordenberg, J.9
-
22
-
-
0030861571
-
Bcl-2 and bax function independently to regulate cell death
-
DOI 10.1038/ng0897-358
-
Knudson, C. M., and Korsmeyer, S. J. Bcl-2 and Bax function independently to regulate cell death. Nat. Genet., 16: 358-363, 1997. (Pubitemid 27323300)
-
(1997)
Nature Genetics
, vol.16
, Issue.4
, pp. 358-363
-
-
Knudson, C.M.1
Korsmeyer, S.J.2
-
23
-
-
0035876483
-
BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak
-
DOI 10.1101/gad.897601
-
Zong, W. X., Lindsten, T., Ross, A. J., MacGregor, G. R., and Thompson, C. B. BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak. Genes Dev., 15: 1481-1486, 2001. (Pubitemid 32552527)
-
(2001)
Genes and Development
, vol.15
, Issue.12
, pp. 1481-1486
-
-
Zong, W.-X.1
Lindsten, T.2
Ross, A.J.3
MacGregor, G.R.4
Thompson, C.B.5
-
24
-
-
84880293228
-
Synergistic induction of apoptosis by simultaneous disruption of the Bcl-2 and MEK/MAPK pathways in acute myelogenous leukemia
-
Milella, M., Estrov, Z., Kornblau, S. M., Konopleva, M., Tari, A. M., Carter, B. Z., Schober, W. D., Harris, D., Leysath, C. E., Lopez-Berestein, G., Huang, Z., and Andreff, M. Synergistic induction of apoptosis by simultaneous disruption of the Bcl-2 and MEK/MAPK pathways in acute myelogenous leukemia. Blood, 98: 840a, 2001. (Pubitemid 33790749)
-
(2001)
Blood
, vol.98
, Issue.11 PART I
-
-
Milella, M.1
Estrov, Z.2
Kornblau, S.M.3
Konopleva, M.4
Tari, A.M.5
Carter, B.Z.6
Schober, W.D.7
Harris, D.8
Leysath, C.E.9
Lopez-Berestein, G.10
Huang, Z.11
Andreeff, M.12
-
25
-
-
0035906835
-
Bcl-2 resistant mitochondrial toxicity mediated by the isoquinoline carboxamide Pk11195 involves de novo generation of reactive oxygen species
-
DOI 10.1054/bjoc.2001.1788
-
Fennell, D. A., Corbo, M., Pallaska, A., and Cotter, F. E. Bcl-2 resistant mitochondrial toxicity mediated by the isoquinoline carboxamide PK11195 involves de novo generation of reactive oxygen species. Br. J. Cancer, 84: 1397-1404, 2001. (Pubitemid 32522111)
-
(2001)
British Journal of Cancer
, vol.84
, Issue.10
, pp. 1397-1404
-
-
Fennell, D.A.1
Corbo, M.2
Pallaska, A.3
Cotter, F.E.4
|