FOXC1 is a potential prognostic biomarker with functional significance in basal-like breast cancer

Cancer Research

Volumn 70, Issue 10, 2010, Pages 3870-3876

  Ray, Partha S ^a   Wang, Jinhua ^a   Qu, Ying ^a,c   Sim, Myung Shin ^a   Shamonki, Jaime ^b   Bagaria, Sanjay P ^a   Ye, Xing ^a   Liu, Bingya ^c   Elashoff, David ^d   Hoon, Dave S ^a   Walter, Michael A ^e   Martens, John W ^f   Richardson, Andrea L ^g   Giuliano, Armando E ^a   Cui, Xiaojiang ^a  

^a JOHN WAYNE CANCER INSTITUTE   (United States)

^b SAINT JOHN'S HEALTH CENTER   (United States)

^c SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY OF ALBERTA   (Canada)

^f ERASMUS MEDICAL CENTER   (Netherlands)

^g BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTION FACTOR FOXC1; TUMOR MARKER;

ARTICLE; BRAIN METASTASIS; BREAST CANCER; CELL INVASION; CELL MIGRATION; CELL PROLIFERATION; GENE EXPRESSION PROFILING; HUMAN; HUMAN CELL; LYMPH NODE METASTASIS; OVERALL SURVIVAL; PRIORITY JOURNAL;

APOPTOSIS; BLOTTING, WESTERN; BONE NEOPLASMS; BREAST; BREAST NEOPLASMS; CARCINOMA, BASAL CELL; CELL ADHESION; CELL MOVEMENT; CELL PROLIFERATION; CELLS, CULTURED; FEMALE; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION PROFILING; HUMANS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROGNOSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, SMALL INTERFERING; SURVIVAL RATE; TUMOR MARKERS, BIOLOGICAL;

EID: 77952821751     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-09-4120     Document Type: Article

References (25)

1. Perou CM, Sorlie T, Eisen MB, et al. Molecular portraits of human breast tumours. Nature 2000;406:747-752
2. Kreike B, van Kouwenhove M, Horlings H, et al. Gene expression profiling and histopathological characterization of triple-negative/ basal-like breast carcinomas. Breast Cancer Res 2007;9:R65. (Pubitemid 350187481)
3. Carey LA, Perou CM, Livasy CA, et al. Race, breast cancer subtypes, and survival in the Carolina Breast Cancer Study. JAMA 2006;295: 2492-2502
4. Dent R, Trudeau M, Pritchard KI, et al. Triple-negative breast cancer: clinical features and patterns of recurrence. Clin Cancer Res 2007; 13:4429-4434 (Pubitemid 47219710)
5. Nielsen TO, Hsu FD, Jensen K, et al. Immunohistochemical and clinical characterization of the basal-like subtype of invasive breast carcinoma. Clin Cancer Res 2004;10:5367-5374 (Pubitemid 39100473)
6. Elsheikh SE, Green AR, Rakha EA, et al. Caveolin 1 and caveolin 2 are associated with breast cancer basal-like and triple-negative immuno-phenotype. Br J Cancer 2008;99:327-334
7. Livasy CA, Karaca G, Nanda R, et al. Phenotypic evaluation of the basal-like subtype of invasive breast carcinoma. Mod Pathol 2006; 19:264-271 (Pubitemid 43117611)
8. Hu Z, Fan C, Oh DS, et al. The molecular portraits of breast tumors are conserved across microarray platforms. BMC Genomics 2006; 7:96.
9. Richardson AL, Wang ZC, De Nicolo A, et al. X chromosomal abnormalities in basal-like human breast cancer. Cancer Cell 2006;9: 121-132 (Pubitemid 43202662)
10. Farmer P, Bonnefoi H, Becette V, et al. Identification of molecular apocrine breast tumours by microarray analysis. Oncogene 2005; 24:4660-4671 (Pubitemid 41032603)
11. Hess KR, Anderson K, Symmans WF, et al. Pharmacogenomic predictor of sensitivity to preoperative chemotherapy with paclitaxel and fluorouracil, doxorubicin, and cyclophosphamide in breast cancer. J Clin Oncol 2006;24:4236-4244 (Pubitemid 46630780)
12. Ivshina AV, George J, Senko O, et al. Genetic reclassification of histologic grade delineates new clinical subtypes of breast cancer. Cancer Res 2006;66:10292-10301 (Pubitemid 44799747)
13. Miller LD, Smeds J, George J, et al. An expression signature for p53 status in human breast cancer predicts mutation status, transcriptional effects, and patient survival. Proc Natl Acad Sci U S A 2005; 102:13550-13555 (Pubitemid 41420886)
14. van de Vijver MJ, He YD, van't Veer LJ, et al. A gene-expression signature as a predictor of survival in breast cancer. N Engl J Med 2002; 347:1999-2009. (Pubitemid 35461656)
15. Herschkowitz JI, Simin K, Weigman VJ, et al. Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors. Genome Biol 2007;8:R76. (Pubitemid 351902765)
16. Sorlie T, Tibshirani R, Parker J, et al. Repeated observation of breast tumor subtypes in independent gene expression data sets. Proc Natl Acad Sci U S A 2003;100:8418-8423 (Pubitemid 36842560)
17. Wang Y, Klijn JG, Zhang Y, et al. Gene-expression profiles to predict distant metastasis of lymph-node-negative primary breast cancer. Lancet 2005;365:671-679 (Pubitemid 40260888)
18. Pawitan Y, Bjohle J, Amler L, et al. Gene expression profiling spares early breast cancer patients from adjuvant therapy: derived and validated in two population-based cohorts. Breast Cancer Res 2005;7: R953-64.
19. Berry FB, Mirzayans F, Walter MA. Regulation of FOXC1 stability and transcriptional activity by an epidermal growth factor-activated mitogen-activated protein kinase signaling cascade. J Biol Chem 2006;281:10098-10104 (Pubitemid 43864545)
20. Akaike H. A new look at the statistical model identification. IEEE Trans Automatic Control 1974;19:716-723
21. Bloushtain-Qimron N, Yao J, Snyder EL, et al. Cell type-specific DNA methylation patterns in the human breast. Proc Natl Acad Sci U S A 2008;105:14076-14081
22. Aslakson CJ, Miller FR. Selective events in the metastatic process defined by analysis of the sequential dissemination of subpopulations of a mouse mammary tumor. Cancer Res 1992;52:1399-1405
23. Seewaldt VL, Scott V. Images in clinical medicine. Rapid progression of basal-type breast cancer. N Engl J Med 2007;356:e12.
24. Sarrio D, Rodriguez-Pinilla SM, Hardisson D, Cano A, Moreno-Bueno G, Palacios J. Epithelial-mesenchymal transition in breast cancer relates to the basal-like phenotype. Cancer Res 2008;68:989-997 (Pubitemid 351272216)
25. Andre F, Job B, Dessen P, et al. Molecular characterization of breast cancer with high-resolution oligonucleotide comparative genomic hybridization array. Clin Cancer Res 2009;15:441-451