Endothelial focal adhesion kinase mediates cancer cell homing to discrete regions of the lungs via E-selectin up-regulation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 9, 2011, Pages 3725-3730

  Hiratsuka, Sachie ^a   Goel, Shom ^a   Kamoun, Walid S ^a   Maru, Yoshiro ^b   Fukumura, Dai ^a   Duda, Dan G ^a   Jain, Rakesh K ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

Author keywords

Metastasis; Permeability

Indexed keywords

ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; FOCAL ADHESION KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL PERMEABILITY; CANCER CELL; CELL HOMING; CONTROLLED STUDY; ENDOTHELIUM CELL; LUNG; LUNG ENDOTHELIUM; METASTASIS; MOUSE; NONHUMAN; PRIMARY TUMOR; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION;

ANIMALS; CELL ADHESION; CELL LINE, TUMOR; CELL MOVEMENT; E-SELECTIN; ENDOTHELIAL CELLS; ENZYME ACTIVATION; FOCAL ADHESION PROTEIN-TYROSINE KINASES; HUMANS; LUNG; MICE; NEOPLASM METASTASIS; NEOPLASMS; NEOPLASTIC CELLS, CIRCULATING; PERMEABILITY; UP-REGULATION;

EID: 79952756887     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1100446108     Document Type: Article

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