Rat model of metastatic breast cancer monitored by MRI at 3 tesla and bioluminescence imaging with histological correlation

Journal of Translational Medicine

Volumn 7, Issue , 2009, Pages

  Song, Ho Taek ^a,b   Jordan, Elaine K ^a   Lewis, Bobbi K ^a   Liu, Wei ^a,c   Ganjei, Justin ^a   Klaunberg, Brenda ^d   Despres, Daryl ^d   Palmieri, Diane ^e   Frank, Joseph A ^a,f  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b Yonsei University College of Medicine   (South Korea)

^c PHILIPS RESEARCH LABORATORIES   (Netherlands)

^d NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^e NATIONAL CANCER INSTITUTE   (United States)

^f NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FIREFLY LUCIFERASE; MAGNETITE; PROTAMINE; SUPERPARAMAGNETIC IRON OXIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOLUMINESCENCE; BRAIN CANCER; BREAST CANCER; CANCER CELL CULTURE; CANCER GROWTH; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; IMAGING; METASTASIS POTENTIAL; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; RAT; SENSITIVITY AND SPECIFICITY; TISSUE DISTRIBUTION; ANIMAL; BONE TUMOR; BRAIN; BRAIN TUMOR; BREAST TUMOR; CHEMISTRY; EXPERIMENTAL NEOPLASM; FEMALE; GENETICS; HISTOLOGY; HUMAN; LUMINESCENCE; METABOLISM; METASTASIS; METHODOLOGY; MOUSE; PATHOLOGY; TUMOR CELL LINE;

ANIMALS; BONE NEOPLASMS; BRAIN; BRAIN NEOPLASMS; BREAST NEOPLASMS; CELL LINE, TUMOR; FEMALE; FERROSOFERRIC OXIDE; HUMANS; LUCIFERASES, FIREFLY; LUMINESCENT MEASUREMENTS; MAGNETIC RESONANCE IMAGING; MAMMARY NEOPLASMS, EXPERIMENTAL; MICE; NEOPLASM METASTASIS; PROTAMINES; RATS;

EID: 71149107667     PISSN: None     EISSN: 14795876     Source Type: Journal    
DOI: 10.1186/1479-5876-7-88     Document Type: Article

References (36)

1. DiStefano A, Yong Yap Y, Hortobagyi GN, Blumenschein GR. The natural history of breast cancer patients with brain metastases. Cancer 1979, 44:1913-1918. 10.1002/1097-0142(197911)44:5<1913::AID-CNCR2820440554>3.0.CO;2-D, 498057.
2. Patchell RA. The management of brain metastases. Cancer Treat Rev 2003, 29:533-540. 10.1016/S0305-7372(03)00105-1, 14585263.
3. Melisko ME, Kunwar S, Prados M, Berger MS, Park JW. Brain metastases of breast cancer. Expert Rev Anticancer Ther 2005, 5:253-268. 10.1586/14737140.5.2.253, 15877523.
4. Mystakidou K, Boviatsis EJ, Kouyialis AT, Voumvourakis K, Kouloulias V, Kouvaris J, Vlahos L. Silent radiological imaging time in patients with brain metastasis. Clin Neurol Neurosurg 2004, 106:300-304. 10.1016/j.clineuro.2004.01.005, 15297004.
5. Yuh WT, Tali ET, Nguyen HD, Simonson TM, Mayr NA, Fisher DJ. The effect of contrast dose, imaging time, and lesion size in the MR detection of intracerebral metastasis. AJNR Am J Neuroradiol 1995, 16:373-380.
6. Sze G, Milano E, Johnson C, Heier L. Detection of brain metastases: comparison of contrast-enhanced MR with unenhanced MR and enhanced CT. AJNR Am J Neuroradiol 1990, 11:785-791.
7. Aragon-Ching JB, Zujewski JA. CNS metastasis: an old problem in a new guise. Clin Cancer Res 2007, 13:1644-1647. 10.1158/1078-0432.CCR-07-0096, 17363516.
8. Sharma M, Abraham J. CNS metastasis in primary breast cancer. Expert Rev Anticancer Ther 2007, 7:1561-1566. 10.1586/14737140.7.11.1561, 18020924.
9. Cailleau R, Young R, Olive M, Reeves WJ. Breast tumor cell lines from pleural effusions. J Natl Cancer Inst 1974, 53:661-674.
10. Rose DP, Connolly JM, Liu XH. Effects of linoleic acid on the growth and metastasis of two human breast cancer cell lines in nude mice and the invasive capacity of these cell lines in vitro. Cancer Res 1994, 54:6557-6562.
11. Yoneda T, Williams PJ, Hiraga T, Niewolna M, Nishimura R. A bone-seeking clone exhibits different biological properties from the MDA-MB-231 parental human breast cancer cells and a brain-seeking clone in vivo and in vitro. J Bone Miner Res 2001, 16:1486-1495. 10.1359/jbmr.2001.16.8.1486, 11499871.
12. Fitzgerald DP, Palmieri D, Hua E, Hargrave E, Herring JM, Qian Y, Vega-Valle E, Weil RJ, Stark AM, Vortmeyer AO, Steeg PS. Reactive glia are recruited by highly proliferative brain metastases of breast cancer and promote tumor cell colonization. Clin Exp Metastasis 2008, 25:799-810. 10.1007/s10585-008-9193-z, 2679391, 18649117.
13. Simoes RV, Martinez-Aranda A, Martin B, Cerdan S, Sierra A, Arus C. Preliminary characterization of an experimental breast cancer cells brain metastasis mouse model by MRI/MRS. MAGMA 2008, 21:237-249. 10.1007/s10334-008-0114-6, 18516631.
14. Palmieri D, Bronder JL, Herring JM, Yoneda T, Weil RJ, Stark AM, Kurek R, Vega-Valle E, Feigenbaum L, Halverson D. Her-2 overexpression increases the metastatic outgrowth of breast cancer cells in the brain. Cancer Res 2007, 67:4190-4198. 10.1158/0008-5472.CAN-06-3316, 17483330.
15. Heyn C, Ronald JA, Ramadan SS, Snir JA, Barry AM, MacKenzie LT, Mikulis DJ, Palmieri D, Bronder JL, Steeg PS. In vivo MRI of cancer cell fate at the single-cell level in a mouse model of breast cancer metastasis to the brain. Magn Reson Med 2006, 56:1001-1010. 10.1002/mrm.21029, 17029229.
16. Arbab AS, Bashaw LA, Miller BR, Jordan EK, Bulte JW, Frank JA. Intracytoplasmic tagging of cells with ferumoxides and transfection agent for cellular magnetic resonance imaging after cell transplantation: methods and techniques. Transplantation 2003, 76:1123-1130. 10.1097/01.TP.0000089237.39220.83, 14557764.
17. Arbab AS, Bashaw LA, Miller BR, Jordan EK, Lewis BK, Kalish H, Frank JA. Characterization of biophysical and metabolic properties of cells labeled with superparamagnetic iron oxide nanoparticles and transfection agent for cellular MR imaging. Radiology 2003, 229:838-846. 10.1148/radiol.2293021215, 14657318.
18. Arbab AS, Yocum GT, Kalish H, Jordan EK, Anderson SA, Khakoo AY, Read EJ, Frank JA. Efficient magnetic cell labeling with protamine sulfate complexed to ferumoxides for cellular MRI. Blood 2004, 104:1217-1223. 10.1182/blood-2004-02-0655, 15100158.
19. Bulte JW, Kraitchman DL. Iron oxide MR contrast agents for molecular and cellular imaging. NMR Biomed 2004, 17:484-499. 10.1002/nbm.924, 15526347.
20. Daldrup-Link HE, Rudelius M, Oostendorp RA, Settles M, Piontek G, Metz S, Rosenbrock H, Keller U, Heinzmann U, Rummeny EJ. Targeting of hematopoietic progenitor cells with MR contrast agents. Radiology 2003, 228:760-767. 10.1148/radiol.2283020322, 12881578.
21. Frank JA, Anderson SA, Kalsih H, Jordan EK, Lewis BK, Yocum GT, Arbab AS. Methods for magnetically labeling stem and other cells for detection by in vivo magnetic resonance imaging. Cytotherapy 2004, 6:621-625.
22. Anderson SA, Frank JA. MRI of mouse models of neurological disorders. NMR Biomed 2007, 20:200-215. 10.1002/nbm.1167, 17451184.
23. Raman V, Pathak AP, Glunde K, Artemov D, Bhujwalla ZM. Magnetic resonance imaging and spectroscopy of transgenic models of cancer. NMR Biomed 2007, 20:186-199. 10.1002/nbm.1136, 17451171.
24. Bulte JW, Douglas T, Witwer B, Zhang SC, Strable E, Lewis BK, Zywicke H, Miller B, van Gelderen P, Moskowitz BM. Magnetodendrimers allow endosomal magnetic labeling and in vivo tracking of stem cells. Nat Biotechnol 2001, 19:1141-1147. 10.1038/nbt1201-1141, 11731783.
25. Frank JA, Miller BR, Arbab AS, Zywicke HA, Jordan EK, Lewis BK, Bryant LH, Bulte JW. Clinically applicable labeling of mammalian and stem cells by combining superparamagnetic iron oxides and transfection agents. Radiology 2003, 228:480-487. 10.1148/radiol.2281020638, 12819345.
26. Levy LM, Di Chiro G, Brooks RA, Dwyer AJ, Wener L, Frank J. Spinal cord artifacts from truncation errors during MR imaging. Radiology 1988, 166:479-483.
27. Jenkins DE, Hornig YS, Oei Y, Dusich J, Purchio T. Bioluminescent human breast cancer cell lines that permit rapid and sensitive in vivo detection of mammary tumors and multiple metastases in immune deficient mice. Breast Cancer Res 2005, 7:R444-454. 10.1186/bcr1026, 1175057, 15987449.
28. Strain Chracteristics of Nude Rat. , http://sierrabiomedical.com/flex_content_area/documents/rm_rm_d_nude_rat 1.pdf
29. Arbab AS, Wilson LB, Ashari P, Jordan EK, Lewis BK, Frank JA. A model of lysosomal metabolism of dextran coated superparamagnetic iron oxide (SPIO) nanoparticles: implications for cellular magnetic resonance imaging. NMR Biomed 2005, 18:383-389. 10.1002/nbm.970, 16013087.
30. Burch S, Bisland SK, Wilson BC, Whyne C, Yee AJ. Multimodality imaging for vertebral metastases in a rat osteolytic model. Clinical Orthopaedics and Related Research 2007, 230-236. 10.1097/01.blo.0000238787.44349.eb, 16924176.
31. Pawelczyk E, Arbab AS, Pandit S, Hu E, Frank JA. Expression of transferrin receptor and ferritin following ferumoxides-protamine sulfate labeling of cells: implications for cellular magnetic resonance imaging. NMR Biomed 2006, 19:581-592. 10.1002/nbm.1038, 16673357.
32. Kuhlpeter R, Dahnke H, Matuszewski L, Persigehl T, von Wallbrunn A, Allkemper T, Heindel WL, Schaeffter T, Bremer C. R2 and R2* mapping for sensing cell-bound superparamagnetic nanoparticles: in vitro and murine in vivo testing. Radiology 2007, 245:449-457. 10.1148/radiol.2451061345, 17848680.
33. Rad AM, Arbab AS, Iskander AS, Jiang Q, Soltanian-Zadeh H. Quantification of superparamagnetic iron oxide (SPIO)-labeled cells using MRI. J Magn Reson Imaging 2007, 26:366-374. 10.1002/jmri.20978, 17623892.
34. Heyn C, Ronald JA, Mackenzie LT, MacDonald IC, Chambers AF, Rutt BK, Foster PJ. In vivo magnetic resonance imaging of single cells in mouse brain with optical validation. Magn Reson Med 2006, 55:23-29. 10.1002/mrm.20747, 16342157.
35. Song H-T, Lewis BK, Liu W, Jordan EK, Klaunberg B, Despress D, Palmieri D, Frank JA. Quantitative measurement of cerebral metastatic tumor burden of breast cancer cells in a nude rat model using T2* map histograms with bioluminescence imaging correlation. Joint Annual Meeting ISMRM-ESMRMB; 19-25 May; Berlin 2007, 196-197.
36. Lee SS, Kim MK, Sym SJ, Kim SW, Kim WK, Kim SB, Ahn JH. Intramedullary spinal cord metastases: a single-institution experience. J Neurooncol 2007, 84:85-89. 10.1007/s11060-007-9345-z, 17310265.