Enhanced tumor uptake of carboplatin and survival in glioma-bearing rats by intracarotid infusion of bradykinin analog, RMP-7

Neurosurgery

Volumn 39, Issue 1, 1996, Pages 125-134

  Matsukado, Koichiro ^a   Inamura, Takanori ^b   Nakano, Shin ^a   Fukui, Masashi ^b   Bartus, Raymond T ^c   Black, Keith L ^a,d  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b KYUSHU UNIVERSITY   (Japan)

^c ALKERMES INC   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Blood brain barrier; Bradykinin; Carboplatin; RG2 glioma; RMP 7

Indexed keywords

BRADYKININ DERIVATIVE; CARBOPLATIN; LOBRADIMIL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTORADIOGRAPHY; BLOOD BRAIN BARRIER; BRAIN TUMOR; CANCER SURVIVAL; CANCER TRANSPLANTATION; CAPILLARY PERMEABILITY; CONTROLLED STUDY; DRUG TRANSPORT; FEMALE; NONHUMAN; PRIORITY JOURNAL; RAT; SURVIVAL RATE;

ANIMALS; ANTINEOPLASTIC AGENTS; AUTORADIOGRAPHY; BLOOD-BRAIN BARRIER; BRADYKININ; BRAIN; BRAIN NEOPLASMS; CAPILLARY PERMEABILITY; CARBOPLATIN; CAROTID ARTERIES; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GLIOMA; INFUSIONS, INTRA-ARTERIAL; INFUSIONS, INTRAVENOUS; RATS; RATS, WISTAR; SURVIVAL RATE;

EID: 0029900093     PISSN: 0148396X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00006123-199607000-00025     Document Type: Article

References (46)

1. Alvarez AL, Delorenzi A, Santajuliana D, Finkielman S, Nahmod VE, Pirola CJ: Central bradykininergic system in normotensive and hypertensive rats. Clin Sci 82:513-519, 1992.
2. Baba T, Black KL, Ikezaki K, Chen KN, Becker DP: Intracarotid infusion of leukotriene C4 selectively increases blood-brain barrier permeability after focal ischemia in rats. J Cereb Blood Flow Metab 11:638-643, 1991.
3. Black KL, Chio CC: Increased opening of blood-tumour barrier by leukotriene C4 is dependent on size of molecules. Neurol Res 14:402-404, 1992.
4. Black K, Hoff J: Leukotrienes increase blood-brain barrier permeability following intraparenchymal injections in rats. Ann Neurol 18:349-351, 1985.
5. Black KL, Baba T, Pardridge WM: Enzymatic barrier protects brain capillaries from leukotriene C4. J Neurosurg 81:745-751, 1994.
6. 4 and vasogenic edema surrounding brain tumors in humans. Ann Neurol 19:592-595, 1986.
7. Black KL, King WA, Ikezaki K: Selective opening of the blood-tumor barrier by intracarotid infusion of leukotriene C4. J Neurosurg 72:912-916, 1990.
8. Blasberg RG, Groothuis D, Molnar P: A review of hyperosmotic blood-brain barrier disruption in seven experimental brain tumor models, in Johansson BB, Owman C, Widner H (eds): Pathophysiology of the Blood-Brain Barrier. New York, Elsevier, 1991, pp 197-220.
9. Canetta R, Rozencweig M, Carter SK: Carboplatin: The clinical spectrum to date. Cancer Treat Rev 12:125-136, 1985.
10. Chan PH, Fishman RA, Caronna J, Schmidley JW, Prioleau G, Lee J: Induction of brain edema following intracerebral injection of arachidonic acid. Ann Neurol 13:625-632, 1983.
11. Chio CC, Baba T, Black KL: Selective blood-tumor barrier disruption by leukotrienes. J Neurosurg 77:407-410, 1992.
12. Doctrow SR, Abelleira SM, Curry LA, Heller-Harrison R, Kozarich JW, Malfroy B, McCarroll LA, Morgan KG, Morrow AR, Musso GF, Smart JL, Straub JA, Turnbull B, Gloff CA: The bradykinin analog RMP-7 increases intracellular free calcium levels in rat brain microvascular endothelial cells. J Pharmacol Exp Ther 271:229-237, 1994.
13. Fenstermacher JD, Cowles AL: Theoretic limitations of intracarotid infusion in brain tumor chemotherapy. Cancer Treat Rep 61:519-526, 1977.
14. + antiport is an early event in hypertrophy of renal proximal tubular cells. Proc Natl Acad Sci U S A 82:1736-1740, 1985.
15. Friedman HS, Krischer JP, Burger P, Oakes WJ, Hockenberger B, Weiner MD, Falletta JM, Norris D, Ragab AH, Mahoney D Jr, Whitehead MV, Kun LE: Treatment of children with progressive or recurrent brain tumors with carboplatin or iproplatin: A Pediatric Oncology Group randomized Phase II study. J Clin Oncol 10:249-256, 1992.
16. Groothuis DR, Fischer JR, Lapin G, Bigner DD, Vick NA: Permeability of different experimental brain tumor models to horseradish peroxidase. J Neuropathol Exp Neurol 41:164-185, 1982.
17. Groothuis DR, Warkne PC, Molnar P, Lapin GD, Mikhael MA: Effect of hyperosmotic blood-brain barrier disruption on transcapillary transport in canine brain tumors. J Neurosurg 72:441-449, 1990.
18. Inamura T, Black K: Bradykinin selectively opens blood-tumor barrier in experimental brain tumors. J Cereb Blood Flow Metab 14:862-870, 1994.
19. Inamura T, Nomura T, Bartus R, Black K: Intracarotid infusion of RMP-7, a bradykinin analog: A method for selective drug delivery to brain tumors. J Neurosurg 81:752-758, 1994.
20. Inamura T, Nomura T, Ikezaki K, Fukui M, Pöllinger G, Black K: Intracarotid histamine infusion increases blood tumor permeability in RG2 glioma. Neurol Res 16:125-128, 1994.
21. Inoue T, Fukui M, Nishio S, Kitamura K, Nagara H: Hyperosmotic blood-brain barrier disruption in brains of rats with an intracerebrally transplanted RG-C6 tumor. J Neurosurg 66:256-263, 1987.
22. Jeremic B, Grujicic D, Jevremovic S, Stanisavljevic B, Milojevic L, Djuric L, Mijatovic L: Carboplatin and etoposide chemotherapy regimen for recurrent malignant glioma: A Phase II study. J Clin Oncol 10:1074-1077, 1992.
23. Ko L, Koestner A, Wechsler W: Morphological characterization of nitrosourea-induced glioma cell lines and clones. Acta Neuropathol (Berl) 51:23-31, 1980.
24. Kumagai AK, Eisenberg JB, Pardridge WM: Absorptive-mediated endocytosis of cationized albumin and a beta-endorphin-cationized albumin chimeric peptide by isolated brain capillaries: Model system of blood-brain barrier transport. J Biol Chem 262: 15214-15219, 1987.
25. Millay RH, Klein ML, Shults WT, Dahlborg SA, Neuwelt EA: Maculopathy associated with combination chemotherapy and osmotic opening of the blood brain barrier. Am J Ophthalmol 102:626-632, 1986.
26. Moskowitz MA, Kiwak KJ, Hekimian K, Levine L: Synthesis of compounds with properties of leukotrienes C4 and D4 in gerbil brains after ischemia and reperfusion. Science 224:886-889, 1984.
27. Nagashima T, Shigin W, Mizoguchi A, Arakawa M, Yamaguchi M, Tamaki N: The effect of leukotriene C4 on the permeability of brain capillary endothelial cell monolayer. Acta Neurochir (Wien) 60:55-57, 1994.
28. Neuwelt EA, Rapoport SI: Modification of the blood-brain barrier in the chemotherapy of malignant brain tumors. Fed Proc 43:214-219, 1984.
29. Neuwelt EA, Barnett PA, Bigner DD, Frenkel EP: Effects of adrenal cortical steroids and osmotic blood-brain barrier opening on methotrexate delivery to gliomas in the redent: The factor of the blood-brain barrier. Proc Natl Acad Sci U S A 79:4420-4423, 1982.
30. Neuwelt EA, Barnett PA, McCormick CI, Frenkel EP, Minna JD: Osmotic blood-brain barrier modification: Monoclonal antibody, albumin, and methotrexate delivery to cerebrospinal fluid and brain. Neurosurgery 17:419-423, 1985.
31. Neuwelt EA, Hill SA, Frenkel EP: Osmotic blood-brain barrier modification and combination chemotherapy: Concurrent tumor regression in areas of barrier opening. Neurosurgery 15:362-366, 1984.
32. Ng KK, Vane JR: Conversion of Angiotensin I to Angiotensin II. Nature 216:762-766, 1967.
33. Nomura T, Inamura T, Black KL: Intracarotid infusion of bradykinin selectively increases blood-tumor permeability in 9L and C6 brain tumors. Brain Res 659:62-66, 1994.
34. Ohno K, Pettigrew KO, Rapoport ST: Lower limits of cerebrovascular permeability to nonelectrolytes in the conscious rat. Am J Physiol 253:H299-H307, 1978.
35. Packer RJ, Lange B, Ater J, Nicholson HS, Allen J, Walker R, Prados M, Jakacki R, Reaman G, Needles MN, Phillips PC, Ryan J, Boyett JM, Geyer R, Finlay J: Carboplatin and vincristine for recurrent and newly diagnosed low-grade gliomas of childhood. J Clin Oncol 11:850-856, 1993.
36. Pardridge WM, Kumagai AK, Eisenberg JB: Chimeric peptides as a vehicle for peptide pharmaceutical delivery through the blood-brain barrier. Biochem Biophys Res Commun 146:307-313, 1987.
37. Raymond JJ, Robertson DM, Dinsdale HB: Pharmacological modification of bradykinin-induced breakdown of the blood-brain barrier. Can J Neurol Sci 13:214-222, 1986.
38. Stewart DJ, Belanger JM, Grahovac Z, Curuvija S, Gionet LR, Aitken SE, Hugenholtz H, Benoit BG, DaSilva VF: Phase I study of intracarotid administration of carboplatin. Neurosurgery 30:512-517, 1992.
39. Tomiwa K, Hazama F, Mikawa H: Neurotoxicity of vincristine after osmotic opening of the blood-brain barrier. Neuropathol Appl Neurobiol 9:345-354, 1983.
40. Warnke PC, Blasberg RG, Groothuis DR: The effect of hyperosmotic blood-brain barrier disruption on blood-to-tissue transport in ENU-induced gliomas. Ann Neurol 22:300-305, 1987.
41. Wechsler W, Ramadan MA, Gieseler A: Isogenic transplantation of ethylnitrosourea-induced tumors of the central and peripheral nervous system in two different inbred rat strains. Naturwissenschaften 59:474, 1972.
42. Williams PC, Henner WD, Roman-Goldstein S, Dahlborg SA, Brummett BE, Tableman M, Dana BW, Neuwelt EA: Toxicity and efficacy of carboplatin and etoposide in conjunction with disruption of the blood-brain tumor barrier in the treatment of intracranial neoplasms. Neurosurgery 37:17-28, 1995.
43. Williams TA, Hooper NM, Turner AJ: Characterization of neuronal and endothelial forms of angiotensin converting enzyme in pig brain. J Neurochem 57:193-199, 1991.
44. Yong T, Gao XP, Koizumi S, Conlon JM, Rennard SI, Mayhan WG, Rubinstein I: Role of peptidases in bradykinin-induced increase in vascular permeability in vivo. Circ Res 70:952-959, 1992.
45. Yung WK, Mechtler L, Gleason MJ: Intravenous carboplatin for recurrent malignant glioma: A Phase II study. J Clin Oncol 9:860-864, 1991.
46. Ziylan YZ, LeFauconnier JM, Bernard G, Bourre JM: Effect of dexamethasone on transport of alpha-aminoisobutyric acid and sucrose across the blood-brain barrier. J Neurochem 51:1338-1342, 1988.