The biology of melanoma brain metastasis

Cancer and Metastasis Reviews

Volumn 18, Issue 3, 1999, Pages 387-400

  Fidler, Isaiah J ^a   Schackert, Gabriele ^a   Zhang, Ruo dan ^a   Radinsky, Robert ^a   Fujimaki, Takamitsu ^a  

^a UNIVERSITY OF TEXAS   (United States)

Author keywords

Angiogenesis; Blood brain barrier; Brain metastasis

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; BIOLOGY; BLOOD BRAIN BARRIER; BRAIN; BRAIN METASTASIS; CANCER GROWTH; CANCER SURVIVAL; CELL PROLIFERATION; GROWTH RATE; LEPTOMENINX; MELANOMA; NONHUMAN; NUDE MOUSE; PRIORITY JOURNAL; PROGNOSIS; REVIEW; SURVIVAL TIME;

ANIMALS; BLOOD-BRAIN BARRIER; BRAIN NEOPLASMS; HUMANS; MELANOMA; MICE;

EID: 0033368578     PISSN: 01677659     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1006329410433     Document Type: Review

References (112)

1. 1. Akslen LA, Hove LM, Hartveit F: Metastatic distribution in malignant melanoma. A 30-year autopsy study. Inv Metastasis 7: 253-263, 1987
2. 2. Takakura K, Sano K, Hojo S, Hirano A: Metastatic Tumors of the Central Nervous System. Igaku-Shoin, Ltd., Tokyo, Japan, 1982
3. 3. Madjewicz ST, Karakousis C, West CR, Caracandas J, Avellanosa AM: Malignant melanoma brain metastases. Review of Roswell Park Memorial Institute experience. Cancer 53: 2550-2562, 1984
4. 4. Kornblith PL, Walker MD, Cassady JR: Neoplasms of the central nervous system. In: DeVita VT, Hellman S, Rosenberg SA (eds) Cancer: Principles and Practice of Oncology, 2nd ed, J B Lippincott, Philadelphia, 1985, pp 1437-1566
5. 5. Schackert G, Fildler IJ: Development of in vivo models for studies of brain metastasis. Int J Cancer 41: 589-594, 1988
6. 6. Fidler IJ, Gruys E, Cifone MA, Barnes Z, Bucana CD: Demonstration of multiple phenotypic diversity in a murine melanoma of recent origin. J Natl Cancer Inst 67: 947-956, 1981
7. 7. Price JE, Aukerman SL, Fidler IJ: Evidence that the process of murine melanoma metastasis is sequential and selective and contains stochastic elements. Cancer Metastasis Rev 46: 5172-5178, 1986
8. 8. MandyburTI: Metastatic brain tumors induced by injection of syngeneic tumor cells into cerebral arterial circulation in rats. Acta Neuropathol 53: 57-64, 1981
9. 9. Fujimaki T, Fan D, Staroselky AH, Gohji K, Bucana CD, Fidler IJ: Critical factors regulating site-specific brain metastasis of murine melanomas. Int J Oncol 3: 789-799, 1993
10. 10. Fidler IJ: Critical factors in the biology of human cancer metastasis: twenty-eighth GHA Clowes Memorial Award Lecture. Cancer Res 50: 6130-6138, 1990
11. 11. Poste G, Fidler IJ: The pathogenesis of cancer metastasis. Nature (Lond) 283: 139-146, 1980
12. 12. Schackert G, Fidler IJ: Site-specific metastasis of mouse melanomas and a fibrosarcoma in the brain or the meninges of syngeneic animals. Cancer Res 48: 3478-3484, 1988
13. 13. Schackert G, Price JE, Zhang RD, Bucana CD, Itoh K, Fidler IJ: Regional growth of different human melanomas as metastases in the brain of nude mice. Am J Pathol 136: 95-102, 1990
14. 125I-5-iodo-2′-deoxyuridine. J Natl Cancer Inst 45: 773-782, 1970
15. 15. Fidler IJ: Selection of successive tumor lines for metastasis. Nature (New Biol) 242: 148-149, 1973
16. 16. Felgenhauer K: The blood-brain barrier redefined. J Neurol 233: 193-194, 1986
17. 14C-alpha-aminoisobutyric acid in rat C6 glioma. J Neurooncol 8: 997-12041, 1990
18. 18. Hart IR, Fidler IJ: Role of organ selectivity in the determination of metastatic patterns of B16 melanoma. Cancer Res 40: 2281-2287, 1980
19. 19. Nicolson GL: Metastatic tumor cell interaction with endothelium, basement membrane and tissue. Curr Opin Cell Biol 1: 1009-1019, 1989
20. 20. Fidler IJ: The relationship of embolic homogeneity, number, size and viability to the incidence of experimental metastasis. Eur J Cancer 9: 223-227, 1973
21. 21. Haynes BF, Telen MJ, Hale LP, Denning SM: CD44 - a molecule involved in leukocyte adherence and T-cell activation. Immunol Today 10: 423-428, 1989
22. 22. Birch M, Mitchell S, Hart IR: Isolation and characterization of human melanoma cell variants expressing high and low levels of CD44. Cancer Res 51: 6660-6667, 1991
23. 23. Hart IR, Birch M, Marshall JF: Cell adhesion receptor expression during melanoma progression and metastasis. Cancer Metastasis Rev 10: 115-128, 1991
24. 24. Lotan R, Amos B, Watanabe H, Raz A: Suppression of motility factor receptor expression by retinoic acid. Cancer Res 52: 4878-4884, 1992
25. 25. Nakajima M, Welch DR, Belloni PN, Nicolson GL: Degradation of basement membrane type IV collagen and lung subendothelial matrix by rat mammary adenocarcinoma cell clones of differing metastatic potential. Cancer Res 47: 4869-4876, 1987
26. 26. Nakajima M, Irimura T, Di Ferrante N, Nicolson G: Heparan sulfate degradation: relation to tumor invasive and metastatic properties of mouse B16 melanoma sublines. Science 220: 611-613, 1983
27. 27. Liotta LA, Rao CN, Barsky SH: Tumor invasion and the extracellular matrix. Lab Invest 49: 636-649, 1983
28. 28. Nicolson GL, Cavanaugh PG, Inoue T: Differential stimulation of the growth of lung-metastasizing tumor cells by lung (paracrine) growth factors: identification of transferrin-like mitogens in lung tissue-conditioned medium (monograph). J Natl Cancer Inst 13: 153-161, 1992
29. 29. Kerbel RS: Expression of multi-cytokine resistance and multi-growth factor independence in advanced stage metastatic cancer: malignant melanoma as a paradigm. Am J Pathol 141: 519-524, 1992
30. 1. Cancer Commun 1: 117-125, 1989
31. 2. Int J Cancer 46: 493-499, 1990
32. 32. Boerner P, Resnick RJ, Racker E: Stimulation of glycolysis and amino uptake in NRK-49F cells by transforming growth factor-β and epidermal growth factor. Proc Natl Acad Sci USA 82: 1350-1353, 1985
33. 33. Roberts AB, Sporn MB, Assoian RK, Smith JM, Roche NS, Wakefield LM, Heine UI, Liotta LA, Falanga V, Kehrl JH, Fauci AS: Transforming growth factor type β: rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro. Proc Natl Acad Sci USA 83: 4167-4717, 1968
34. 34. Ignotz RA, Massague J: Transforming growth factor-β stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix. J Biol Chem 261: 4337-4347, 1986
35. 35. Laiho M, deCaprio JA, Ludlow JW, Livingston DM, Massague J: Growth inhibition by TGF-β linked to suppression of retinoblastoma protein phosphorylation. Cell 62: 175-185, 1990
36. 36. Knabbe C, Lippman ME, Wakefield LM, Flanders AK, Derynck R, Dickson RB: Evidence that transforming growth factor is a hormonally regulated negative growth factor in human breast cancer cells. Cell 48: 417-428, 1987
37. 37. Tucker RF, Shipley GD, Moses HL, Holley RW: Growth inhibitor from BSC-1 cells closely related platelet type beta transforming growth factor. Science 226: 705-707, 1984
38. 38. Anzano MA, Roberts AB, Sporn MB: Anchorage-independent growth of primary rat embryo cells is induced by platelet-derived growth factor and inhibited by type-beta transforming growth factor. J Cell Physiol 126: 312-318, 1986
39. 39. Baird A, Drukin T: Inhibition of endothelial cell proliferation by type-beta transforming growth factor: interaction with acid and basic fibroblast growth factors. Biochem Biophys Res Commun 138: 476-482, 1986
40. 1. Cancer Commun 1: 117-125, 1989
41. 41. Geiser AG, Burnester JK, Wevvink R, Roberts AB, Sporn MB: Inhibition of growth by transforming growth factors following fusion of two nonresponsive human carcinoma cell lines. J Biol Chem 267: 2588-2593, 1992
42. 42. Unsicker K, Flanders KC, Cissel DS, Lafyatis R, Sporn MB: Transforming growth factor beta isoforms in the adult rat central and peripheral nervous system. Neuroscience 44: 513-525, 1991
43. 43. Flanders KC, Ludecke G, Engles S, Cissel DS, Roberts AB, Kondaiah P, Lafyatis R, Sporn MB, Unsicker K: Localization and actions of transforming growth factor-β in the embryonic nervous system. Development 113: 183-191, 1991
44. 1, and NGF differently regulate neural recognition molecule expression by cultured astrocytes. J Cell Biol 115: 473-484, 1991
45. 2 cDNA sequence and expression in adult tissues and embryos. Mol Endocrinol 3: 1108-1114, 1989
46. 46. Schackert G, Price JE, Zhang RD, Bucana CD, Itoh K, Fidler IJ: Regional growth of different human melanomas as metastases in the brain of nude mice. Am J Pathol 136: 95-102, 1990
47. 47. Fujimaki T, Price JE, Fan D, Bucana CD, Itoh K, Kirino T, Fidler IJ: Selective growth of human melanoma cells in the brain parenchyma of nude mice. Melanoma Res 6: 363-371, 1996
48. 48. Tsukuda T, Fouad A, Pickren JW: Central nervous system metastasis from breast carcinoma: autopsy study. Cancer 52: 2349-2354, 1983
49. 49. Viadana E, Bross IDJ, Pickren JW: The metastatic spread of cancers of the digestive system in man. Oncology 35: 114-126, 1978
50. 50. Weiss L: Principles of Metastasis. Academic Press, Orlando, 1985
51. 51. Kanematsu T, Matsumata T, Takenaka K, Yoshida T, Higashi H, Sugimachi K: Clinical managemenl of recurrent hepatocellular carcinoma after primary resection. Br J Surg 75: 203-206, 1988
52. 52. Nicolson GL: Organ specificity of tumor metastasis: role of preferential adhesion, invasion, and growth of malignant cells at specific secondary sites. Cancer Metastasis Rev 7: 143-188, 1988
53. 53. Brunson KW, Beattie G, Nicolson G: Selection and altered properties of brain colonizing metastatic melanoma. Nature 272: 543-545, 1978
54. 54. Zhang RD, Price JE, Schackert G, Itoh K, Fidler IJ: Malignant potential of cells isolated from lymph node or brain metastases of melanoma patients and implications for prognosis. Cancer Res 51: 2029-2035, 1991
55. 55. Li L, Price JE, Fan D, Zhang R, Bucana CD, Fidler IJ: Correlation of growth capacity of human tumor cells in hard agarose with their in vivo proliferative capacity at specific metastatic sites. J Natl Cancer Inst 81: 1406-1412, 1989
56. 56. Tomlinson E: Theory and practice of site-specific drug delivery. Adv Drug Del Rev 1: 187-198, 1987
57. 57. Johansson BB: The physiology of the blood-brain barrier. Adv Exp Med Biol 274: 25-39, 1990
58. 58. Gregoire N: The blood-brain barrier. J Neuroradiol 16: 238-250, 1989
59. 59. Pardridge WM, Oldendorf WH, Cancilla P, Frank HJ: Blood-brain barrier: interface between internal medicine and the brain clinical conference. Ann Intern Med 105: 82-95, 1986
60. 60. Medawar PB: Immunity to homologous grafted skin: III. The fate of skin homografts transplated to the brain, to subcutaneous tissue, and to the anterior chamber of the eye. Br J Exp Pathol 29: 58-69, 1948
61. 61. Scheinberg LC, Edelman FL, Levy WA: Is the brain 'an immunologically privileged site'? Arch Neurol 11: 248-264, 1964
62. 62. Felgenhauer K: The blood-brain barrier redefined. J Neurol 233: 193-194, 1986
63. 63. Shapiro WR, Shapiro JR: Principles of brain tumor chemotherapy. Semin Oncol 13: 56-69, 1986
64. 64. Debbage PL, Gabius HJ, Bise K, Marguth F: Cellular glyco-conjugates and their potential endogenous receptors in the cerebral microvasculature of man: aglycohistochemical study. Eur J Cell Biol 46: 425-434, 1988
65. 65. Steward PA, Hayakawa K, Farrell CL, Del Maestro RF: Quantitative study of microvessel ultrastructure in human peritumoral brain tissue. Evidence for a blood-brain barrier defect. J Neurosurg 67: 697-705, 1987
66. 66. Zagzag D, Goldenberg M, Brem S: Angiogenesis and blood-brain barrier breakdown modulate CT contrast enhancement: an experimental study in a rabbit brain-tumor model. AJR 153: 141-146, 1989
67. 67. Iannotti F, Fleschi C, Alfano B, Picozzi P, Mansi L, Pozzili C, Punzo A, Del Vecchio G, Lenzi GL, Salvatore M: Simplified, noninvasive PET measurement of blood brain barrier permeability. J Comput Assist Tomogr 11: 390-397, 1987
68. 68. Frong D, Israel O, Kohn S, Nir I: The blood-tissue barrier of human brain tumors: correlation of scintigraphic and ultrastructural findings (concise communication). J Nucl Med 25: 461-465, 1984
69. 69. Kohn S, Front D, Nir I: Blood-brain barrier permeability of human gliomas as determined by quantitation of cytoplasmic vesicles of the capillary endothelium and scintigraphic findings. Cancer Invest 7: 313-321, 1989
70. 99Tc-glucoheptonate and alteration in blood-brain barrier as determined by cytochemistry and election microscopy. Neurosurgery 25: 523-532, 1989
71. 71. Coomber BL, Stewart PA, Hayakawa K, Farrell CL, Del Maestro RF: Quantitative morphology of human gliobalstoma multiform microvessels: structural basis of blood-brain barrier defect. J Neurooncol 5: 299-307, 1987
72. 72. Vriesendorp FJ, Peagram C, Bigner DD, Groothuis DR: Concurrent measurements of blood flow and transcapillary transport in xenotransplated human gliomas in immunosuppressed rats. J Natl Cancer Inst 79: 123-130, 1987
73. 73. Nicolson GL: Organ specificity of cancer metastasis is determined, in part, by tumor cell properties and cytokines expressed at particular organ sites. Am Assoc Cancer Res 31: 506-507, 1990
74. 74. Schlingemann RO, Rivetveld FJ, De Wall RM, Ferrone S: Expression of the high molecular weight melanoma-associated antigen by pericytes during angiogenesis in tumors and in healing wounds. Am J Pathol 136: 1393-1405, 1990
75. 75. Zuelch KG: Brain tumors: their biology and pathology, 3rd edn, Springer-Verlag, Berlin, 1986, pp 480-498
76. 76. Greig NH: Optimizing drug delivery to brain tumors. Cancer Treat Rev 13: 1-28, 1987
77. 77. Genka S, Deutsch J, Stahle PL, Shetty UH, John V, Robinson C, Rapoport SI, Greig NH: Brain and plasma pharmacokinetics and anticancer activities of cyclophosphamide and phosphoamide mustard in the rat. Cancer Chemother 27: 1-7, 1990
78. 78. Greig NH, Soncrant TT, Shetty HU, Momma S, Smith QR, Rapoport SI: Brain uptake and anticancer activities of vincristine and vinblastine are restricted by their low cerebrovascular permeability and binding to plasma constituents in rat. Cancer Chemother Pharmacol 26: 263-268, 1990
79. 79. Owman C, Hardebo JE: Functional heterogeneity of the cerebrovascular endothelium. Brain Behav Evol 32: 65-75, 1988
80. 80. Fenstermacher J, Gross P, Sposito N, Acuff V, Pettersen S, Gruber K: Structural and functional variations in capillary systems within the brain. Ann NY Acad Sci 529: 21-30, 1988
81. 81. Baur HC, Tontsch U, Amberger A, Bauer H: Gamma-glutamyl-transpeptidase (GGTP) and NA+K(+)-ATPase activities in different subpopulations of cloned cerebral endothelial cells: responses to glial stimulation. Biochem Biophys Res Commun 168: 358-363, 1990
82. 82. Schackert G, Simmons RD, Buzbee TM, Hume DA, Fidler IJ: Macrophage infiltration into experimental brain metastases: occurrence through an intact blood-brain barrier. J Natl Cancer Inst 80: 1027-1034, 1988
83. 83. Nakagawa Y, Fujimoto N, Matsumoto K, Cervos Navarro J: Morphological changes in acute cerebral ischemia after occlusion and reperfusion in the rat. Adv Neurol 52: 21-27, 1990
84. 84. Kawamura S, Schurer L, Goetz A, Kempski O, Schumucker B, Baethmann A: An improved closed cranial window technique for investigation of blood-brain barrier function and cerebral vasomotor control in the rat. Int J Microcirc Clin Exp 9: 369-383, 1990
85. 85. Malmgren LT, Olsson Y: Differences between the peripheral and the central nervous system in permeability to sodium fluoresein. J Comp Neurol 191: 103-117, 1980
86. 86. Zhang R, Price JE, Fujimaki T, Bucana CD, Fidler IJ: Differential permeability of the blood-brain barrier in experimental brain metastases produced by human neoplasms implanted into nude mice. Am J Pathol 141: 1115-1124, 1992
87. 87. Ballinger WE Jr, Schimpff RD: An experimental model for cerebral metastasis: preliminary light and ultrastructural studies. J Neuropath Exp Neurol 38: 19-34, 1979
88. 88. Hirano A, Zimmerman HM: Fenestrated blood vessels in metastatic renal carcinoma in the brain. Lab Invest 26: 465-468, 1972
89. 89. Dietrich WD, Busto R, Hailey M, Valdes I: The importance of brain temperature in alterations of the blood-brain barrier following cerebral ischemia. J Neuropathol Exp Neurol 49: 486-497, 1990
90. 90. Goldstein GW: Endothelial cell-astrocyte interactions: a cellular model of the blood-brain barrier. Ann NY Acad Sci 529: 31-39, 1988
91. 91. Eberle AN: The Melanotropins: Chemistry, Physiology, and Mechanisms of Action. Karger, Basel, 1988
92. 92. Clive D, Snell DS: Effect of MSH on mammalian hair color. J Invest Dermatol 49: 314-321, 1972
93. 93. Burchill SA, Virden R, Thody AJ: Regulation of tyrosinase and its processing in the hair follicular melanocytes of the mouse during melanogenesis an phacomelanogenesis. J Invest Dermatol 93: 236-240, 1989
94. 94. Pawelek J, Wong G, Sansone J, Morowitz J: Molecular controls in mammalian pigmentation. Yale J Biol Med 46: 430-443, 1973
95. 95. Halaban R, Pomerantz SH, Marshall S, Lambert DT, Lerner AB: Regulation of tyrosinase in human melanocytes grown in culture. J Cell Biol 97: 480-488, 1983
96. 96. Fuller BB, Meyskins FL: Endocrine responsiveness in human melanocytes and melanoma cells in culture. J Natl Cancer Inst 66: 799-802, 1981
97. 97. Friedman PS, Wren F, Buffey J, MacNeil S: α-MSH causes a small rise in cAMP but has no effect on basal or ultraviolet-stimulated melanogenesis in human melanocytes. Br J Dermatol 123: 145-151, 1990
98. 98. Seechrun P, Thody AJ: The effect of UV-irradiation and MSH on tyrosinase activity in epidermal melanocyte of the mouse. J Dermatol Sci 1: 283-288, 1990
99. 99. Halaban R, Pomerantz SH, Marshall S, Lerner AB: Tyrosinase activity and its abundance in Cloudman melanoma cells. Arch Biochem Biophys 230: 383-387, 1984
100. 100. Hill S, Buffey J, Thody AJ, Oliver I, Bleehen SS, MacNeil S: Investigation of the regulation of pigmentation in melanocyte-stimulating hormone responsive and unresponsive cultured B16 murine melanoma cells. Pigm Cell Res 2: 161-166, 1989
101. 101. Salomon Y, Zohar M, DeJordy JO, Eshel Y, Shafir I, Lieba H, Garty NB, Schmidt-Sole J, Azard A, Shai E, Degani H: Signaling mechanisms controlled by melanocortins in melanoma, lacrimal, and brain astroglia cells. Ann NY Acad Sci 680: 364-380, 1993
102. 102. Mountjoy KG, Robbins LS, Mortrud MT, Cone RD: The cloning of a family of genes that encode the melanocortin receptors. Science (Washington, DC) 257: 1248-1251, 1992
103. 103. Chhajlani V, Wiberg JES: Molecular cloning and expression of the human melanocyte-stimulating hormone receptor cDNA. FEBS Lett 3: 417-420, 1992
104. 104. Nakajima M, Morikawa K, Fabra A, Bucana CD, Fidler IJ: Influence of organ environment on extracellular matrix degradative activity and metastasis of human colon carcinoma cells. J Natl Cancer Inst 82: 1890-1898, 1990
105. 105. Fabra A, Nakajima M, Bucana CD, Fidler IJ: Modulation of the invasive phenotype of human colon carcinoma cells by fibroblasts from orthotopic or ectopic organs of nude mice. Differentiation 52: 101-110, 1992
106. 106. Gohji K, Fidler IJ, Fabra A, Bucana CD, von Eschenbach AC, Nakajima M: Regulation of gelatinase production in metastatic renal cell carcinoma by organ-specific fibroblasts. Jpn J Cancer Res 85: 152-160, 1994
107. 107. Fidler IJ: Modulation of the organ microenviornment for the treatment of cancer metastasis (commentary). J Natl Cancer Inst 87: 1588-1592, 1995
108. 108. Singh RK, Gutman M, Radinsky R, Bucana CD, Fidler IJ: Expression of interleukin-8 correlates with the metastatic potential of human melanoma cells in nude mice. Cancer Res 54: 3242-3247, 1994
109. 109. Gutman M, Singh RK, Xie K, Bucana CD, Fidler IJ: Regulation of IL-8 expression in human melanoma cells by the organ environment. Cancer Res 55: 2470-2475, 1995
110. 110. Dong Z, Radinsky R, Fan D, Tsan R, Bucana CD, Wilmanns C, Fidler IJ: Organ-specific modulation of steady-state mdr gene expression and drug resistance in murine colon cancer cells. J Natl Cancer Inst 86: 913-920, 1994
111. 111. Radinsky R, Fidler IJ, Price JE, Esumi N, Tsan R, Petty CM, Bucana CD, Bar-Eli M: Terminal differentiation and apoptosis in experimental lung metastases of human osteogenic sarcoma cells by wild type p53. Oncogene 9: 1877-1883, 1994
112. 112. Radinsky R, Beltran PJ, Tsan R, Zhang R, Cone RD, Fidler IJ: Transcriptional induction of the melanocyte stimulating hormone receptor in brain metastases of murine K-1735 melanoma. Cancer Res 55: 141-148, 1995