-
1
-
-
0025370815
-
Dominant forces in protein folding
-
Dill K.A. Dominant forces in protein folding. Biochemistry 1990, 29:7133-7155.
-
(1990)
Biochemistry
, vol.29
, pp. 7133-7155
-
-
Dill, K.A.1
-
2
-
-
0027256739
-
Hydrogen bonding, hydrophobicity, packing, and protein folding
-
Rose G.D., Wolfenden R. Hydrogen bonding, hydrophobicity, packing, and protein folding. Annu Rev Biophys Biomol Struct 1993, 22:381-415.
-
(1993)
Annu Rev Biophys Biomol Struct
, vol.22
, pp. 381-415
-
-
Rose, G.D.1
Wolfenden, R.2
-
3
-
-
2342649511
-
Combinatorial approaches to protein stability and structure
-
Magliery T.J., Regan L. Combinatorial approaches to protein stability and structure. Eur J Biochem 2004, 271:1595-1608.
-
(2004)
Eur J Biochem
, vol.271
, pp. 1595-1608
-
-
Magliery, T.J.1
Regan, L.2
-
4
-
-
33751209173
-
High-throughput screening for enhanced protein stability
-
Bommarius A.S., Broering J.M., Chaparro-Riggers J.F., Polizzi K.M. High-throughput screening for enhanced protein stability. Curr Opin Biotechnol 2006, 17:606-610.
-
(2006)
Curr Opin Biotechnol
, vol.17
, pp. 606-610
-
-
Bommarius, A.S.1
Broering, J.M.2
Chaparro-Riggers, J.F.3
Polizzi, K.M.4
-
5
-
-
13844281394
-
Directed evolution of proteins for heterologous expression and stability
-
Roodveldt C., Aharoni A., Tawfik D.S. Directed evolution of proteins for heterologous expression and stability. Curr Opin Struct Biol 2005, 15:50-56.
-
(2005)
Curr Opin Struct Biol
, vol.15
, pp. 50-56
-
-
Roodveldt, C.1
Aharoni, A.2
Tawfik, D.S.3
-
6
-
-
60649093306
-
High throughput methods of assessing protein stability and aggregation
-
Senisterra G.A., Finerty P.J. High throughput methods of assessing protein stability and aggregation. Mol Biosyst 2009, 5:217-223.
-
(2009)
Mol Biosyst
, vol.5
, pp. 217-223
-
-
Senisterra, G.A.1
Finerty, P.J.2
-
7
-
-
0032573217
-
Directed evolution of a thermostable esterase
-
Giver L., Gershenson A., Freskgard P.O., Arnold F.H. Directed evolution of a thermostable esterase. Proc Natl Acad Sci USA 1998, 95:12809-12813.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 12809-12813
-
-
Giver, L.1
Gershenson, A.2
Freskgard, P.O.3
Arnold, F.H.4
-
8
-
-
71149120194
-
Optimizing protein stability in vivo
-
Foit L., Morgan G.J., Kern M.J., Steimer L.R., von Hacht A.A., Titchmarsh J., Warriner S.L., Radford S.E., Bardwell J.C. Optimizing protein stability in vivo. Mol Cell 2009, 36:861-871.
-
(2009)
Mol Cell
, vol.36
, pp. 861-871
-
-
Foit, L.1
Morgan, G.J.2
Kern, M.J.3
Steimer, L.R.4
von Hacht, A.A.5
Titchmarsh, J.6
Warriner, S.L.7
Radford, S.E.8
Bardwell, J.C.9
-
9
-
-
18744391410
-
Pulse proteolysis: a simple method for quantitative determination of protein stability and ligand binding
-
Park C., Marqusee S. Pulse proteolysis: a simple method for quantitative determination of protein stability and ligand binding. Nat Methods 2005, 2:207-212.
-
(2005)
Nat Methods
, vol.2
, pp. 207-212
-
-
Park, C.1
Marqusee, S.2
-
10
-
-
34247180735
-
Energetics-based protein profiling on a proteomic scale: identification of proteins resistant to proteolysis
-
Park C., Zhou S., Gilmore J., Marqusee S. Energetics-based protein profiling on a proteomic scale: identification of proteins resistant to proteolysis. J Mol Biol 2007, 368:1426-1437.
-
(2007)
J Mol Biol
, vol.368
, pp. 1426-1437
-
-
Park, C.1
Zhou, S.2
Gilmore, J.3
Marqusee, S.4
-
11
-
-
0032514623
-
Oligomerization domain-directed reassembly of active dihydrofolate reductase from rationally designed fragments
-
Pelletier J.N., Campbell-Valois F.X., Michnick S.W. Oligomerization domain-directed reassembly of active dihydrofolate reductase from rationally designed fragments. Proc Natl Acad Sci USA 1998, 95:12141-12146.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 12141-12146
-
-
Pelletier, J.N.1
Campbell-Valois, F.X.2
Michnick, S.W.3
-
12
-
-
0034647238
-
Antiparallel leucine zipper-directed protein reassembly: application to the green fluorescent protein
-
Ghosh I., Hamilton A.D., Regan L. Antiparallel leucine zipper-directed protein reassembly: application to the green fluorescent protein. J Am Chem Soc 2000, 122:5658-5659.
-
(2000)
J Am Chem Soc
, vol.122
, pp. 5658-5659
-
-
Ghosh, I.1
Hamilton, A.D.2
Regan, L.3
-
13
-
-
0036241055
-
Visualization of interactions among bZIP and Rel family proteins in living cells using bimolecular fluorescence complementation
-
Hu C.D., Chinenov Y., Kerppola T.K. Visualization of interactions among bZIP and Rel family proteins in living cells using bimolecular fluorescence complementation. Mol Cell 2002, 9:789-798.
-
(2002)
Mol Cell
, vol.9
, pp. 789-798
-
-
Hu, C.D.1
Chinenov, Y.2
Kerppola, T.K.3
-
14
-
-
0037180571
-
Noninvasive imaging of protein-protein interactions in living subjects by using reporter protein complementation and reconstitution strategies
-
Paulmurugan R., Umezawa Y., Gambhir S.S. Noninvasive imaging of protein-protein interactions in living subjects by using reporter protein complementation and reconstitution strategies. Proc Natl Acad Sci USA 2002, 99:15608-15613.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 15608-15613
-
-
Paulmurugan, R.1
Umezawa, Y.2
Gambhir, S.S.3
-
15
-
-
11844252081
-
Detecting protein-protein interactions with a green fluorescent protein fragment reassembly trap: scope and mechanism
-
Magliery T.J., Wilson C.G., Pan W., Mishler D., Ghosh I., Hamilton A.D., Regan L. Detecting protein-protein interactions with a green fluorescent protein fragment reassembly trap: scope and mechanism. J Am Chem Soc 2005, 127:146-157.
-
(2005)
J Am Chem Soc
, vol.127
, pp. 146-157
-
-
Magliery, T.J.1
Wilson, C.G.2
Pan, W.3
Mishler, D.4
Ghosh, I.5
Hamilton, A.D.6
Regan, L.7
-
16
-
-
36749104291
-
Quantification of dynamic protein complexes using Renilla luciferase fragment complementation applied to protein kinase A activities in vivo
-
Stefan E., Aquin S., Berger N., Landry C.R., Nyfeler B., Bouvier M., Michnick S.W. Quantification of dynamic protein complexes using Renilla luciferase fragment complementation applied to protein kinase A activities in vivo. Proc Natl Acad Sci USA 2007, 104:16916-16921.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 16916-16921
-
-
Stefan, E.1
Aquin, S.2
Berger, N.3
Landry, C.R.4
Nyfeler, B.5
Bouvier, M.6
Michnick, S.W.7
-
17
-
-
50149117570
-
High-throughput analysis of the protein sequence-stability landscape using a quantitative yeast surface two-hybrid system and fragment reconstitution
-
Dutta S., Koide A., Koide S. High-throughput analysis of the protein sequence-stability landscape using a quantitative yeast surface two-hybrid system and fragment reconstitution. J Mol Biol 2008, 382:721-733.
-
(2008)
J Mol Biol
, vol.382
, pp. 721-733
-
-
Dutta, S.1
Koide, A.2
Koide, S.3
-
18
-
-
78650530108
-
In vivo protein stabilization based on fragment complementation and a split GFP system
-
Lindman S., Hernandez-Garcia A., Szczepankiewicz O., Frohm B., Linse S. In vivo protein stabilization based on fragment complementation and a split GFP system. Proc Natl Acad Sci USA 2010, 107:19826-19831.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 19826-19831
-
-
Lindman, S.1
Hernandez-Garcia, A.2
Szczepankiewicz, O.3
Frohm, B.4
Linse, S.5
-
19
-
-
0033015460
-
Rapid protein-folding assay using green fluorescent protein
-
Waldo G.S., Standish B.M., Berendzen J., Terwilliger T.C. Rapid protein-folding assay using green fluorescent protein. Nat Biotechnol 1999, 17:691-695.
-
(1999)
Nat Biotechnol
, vol.17
, pp. 691-695
-
-
Waldo, G.S.1
Standish, B.M.2
Berendzen, J.3
Terwilliger, T.C.4
-
20
-
-
13244296604
-
Protein tagging and detection with engineered self-assembling fragments of green fluorescent protein
-
Cabantous S., Terwilliger T.C., Waldo G.S. Protein tagging and detection with engineered self-assembling fragments of green fluorescent protein. Nat Biotechnol 2005, 23:102-107.
-
(2005)
Nat Biotechnol
, vol.23
, pp. 102-107
-
-
Cabantous, S.1
Terwilliger, T.C.2
Waldo, G.S.3
-
21
-
-
60849139060
-
Automated, high-throughput platform for protein solubility screening using a split-GFP system
-
Listwan P., Terwilliger T.C., Waldo G.S. Automated, high-throughput platform for protein solubility screening using a split-GFP system. J Struct Funct Genomics 2009, 10:47-55.
-
(2009)
J Struct Funct Genomics
, vol.10
, pp. 47-55
-
-
Listwan, P.1
Terwilliger, T.C.2
Waldo, G.S.3
-
22
-
-
0028999630
-
Instrumentation for automated determination of protein stability
-
Stites W.E., Byrne M.P., Aviv J., Kaplan M., Curtis P.M. Instrumentation for automated determination of protein stability. Anal Biochem 1995, 227:112-122.
-
(1995)
Anal Biochem
, vol.227
, pp. 112-122
-
-
Stites, W.E.1
Byrne, M.P.2
Aviv, J.3
Kaplan, M.4
Curtis, P.M.5
-
23
-
-
0038275885
-
High-precision, high-throughput stability determinations facilitated by robotics and a semiautomated titrating fluorometer
-
Edgell M.H., Sims D.A., Pielak G.J., Yi F. High-precision, high-throughput stability determinations facilitated by robotics and a semiautomated titrating fluorometer. Biochemistry 2003, 42:7587-7593.
-
(2003)
Biochemistry
, vol.42
, pp. 7587-7593
-
-
Edgell, M.H.1
Sims, D.A.2
Pielak, G.J.3
Yi, F.4
-
24
-
-
15944380354
-
High-throughput measurement of protein stability in microtiter plates
-
Aucamp J.P., Cosme A.M., Lye G.J., Dalby P.A. High-throughput measurement of protein stability in microtiter plates. Biotechnol Bioeng 2005, 89:599-607.
-
(2005)
Biotechnol Bioeng
, vol.89
, pp. 599-607
-
-
Aucamp, J.P.1
Cosme, A.M.2
Lye, G.J.3
Dalby, P.A.4
-
25
-
-
78650566901
-
Experimental library screening demonstrates the successful application of computational protein design to large structural ensembles
-
Allen B.D., Nisthal A., Mayo S.L. Experimental library screening demonstrates the successful application of computational protein design to large structural ensembles. Proc Natl Acad Sci USA 2010, 107:19838-19843.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 19838-19843
-
-
Allen, B.D.1
Nisthal, A.2
Mayo, S.L.3
-
26
-
-
77955120354
-
Protein denaturation and protein:drugs interactions from intrinsic protein fluorescence measurements at the nanolitre scale
-
Gaudet M., Remtulla N., Jackson S.E., Main E.R., Bracewell D.G., Aeppli G., Dalby P.A. Protein denaturation and protein:drugs interactions from intrinsic protein fluorescence measurements at the nanolitre scale. Protein Sci 2010, 19:1544-1554.
-
(2010)
Protein Sci
, vol.19
, pp. 1544-1554
-
-
Gaudet, M.1
Remtulla, N.2
Jackson, S.E.3
Main, E.R.4
Bracewell, D.G.5
Aeppli, G.6
Dalby, P.A.7
-
27
-
-
0034682492
-
A quantitative, high-throughput screen for protein stability
-
Ghaemmaghami S., Fitzgerald M.C., Oas T.G. A quantitative, high-throughput screen for protein stability. Proc Natl Acad Sci USA 2000, 97:8296-8301.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 8296-8301
-
-
Ghaemmaghami, S.1
Fitzgerald, M.C.2
Oas, T.G.3
-
28
-
-
0034814860
-
Quantitative protein stability measurement in vivo
-
Ghaemmaghami S., Oas T.G. Quantitative protein stability measurement in vivo. Nat Struct Biol 2001, 8:879-882.
-
(2001)
Nat Struct Biol
, vol.8
, pp. 879-882
-
-
Ghaemmaghami, S.1
Oas, T.G.2
-
29
-
-
0347004717
-
Monitoring protein stability and aggregation in vivo by real-time fluorescent labeling
-
Ignatova Z., Gierasch L.M. Monitoring protein stability and aggregation in vivo by real-time fluorescent labeling. Proc Natl Acad Sci USA 2004, 101:523-528.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 523-528
-
-
Ignatova, Z.1
Gierasch, L.M.2
-
30
-
-
44949229448
-
Thermodynamic analysis of protein stability and ligand binding using a chemical modification- and mass spectrometry-based strategy
-
West G.M., Tang L., Fitzgerald M.C. Thermodynamic analysis of protein stability and ligand binding using a chemical modification- and mass spectrometry-based strategy. Anal Chem 2008, 80:4175-4185.
-
(2008)
Anal Chem
, vol.80
, pp. 4175-4185
-
-
West, G.M.1
Tang, L.2
Fitzgerald, M.C.3
-
31
-
-
0037163079
-
Rapid mapping of protein structure, interactions, and ligand binding by misincorporation proton-alkyl exchange
-
Silverman J.A., Harbury P.B. Rapid mapping of protein structure, interactions, and ligand binding by misincorporation proton-alkyl exchange. J Biol Chem 2002, 277:30968-30975.
-
(2002)
J Biol Chem
, vol.277
, pp. 30968-30975
-
-
Silverman, J.A.1
Harbury, P.B.2
-
32
-
-
79958005024
-
A miniaturized technique for assessing protein thermodynamics and function using fast determination of quantitative cysteine reactivity
-
Isom D.G., Marguet P.R., Oas T.G., Hellinga H.W. A miniaturized technique for assessing protein thermodynamics and function using fast determination of quantitative cysteine reactivity. Proteins 2010.
-
(2010)
Proteins
-
-
Isom, D.G.1
Marguet, P.R.2
Oas, T.G.3
Hellinga, H.W.4
-
33
-
-
77950440622
-
Picomole-scale characterization of protein stability and function by quantitative cysteine reactivity
-
Isom D.G., Vardy E., Oas T.G., Hellinga H.W. Picomole-scale characterization of protein stability and function by quantitative cysteine reactivity. Proc Natl Acad Sci USA 2010, 107:4908-4913.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 4908-4913
-
-
Isom, D.G.1
Vardy, E.2
Oas, T.G.3
Hellinga, H.W.4
-
34
-
-
33751559579
-
Screening for ligands using a generic and high-throughput light-scattering-based assay
-
Senisterra G.A., Markin E., Yamazaki K., Hui R., Vedadi M., Awrey D.E. Screening for ligands using a generic and high-throughput light-scattering-based assay. J Biomol Screen 2006, 11:940-948.
-
(2006)
J Biomol Screen
, vol.11
, pp. 940-948
-
-
Senisterra, G.A.1
Markin, E.2
Yamazaki, K.3
Hui, R.4
Vedadi, M.5
Awrey, D.E.6
-
35
-
-
44849085505
-
Application of high-throughput isothermal denaturation to assess protein stability and screen for ligands
-
Senisterra G.A., Soo Hong B., Park H.W., Vedadi M. Application of high-throughput isothermal denaturation to assess protein stability and screen for ligands. J Biomol Screen 2008, 13:337-342.
-
(2008)
J Biomol Screen
, vol.13
, pp. 337-342
-
-
Senisterra, G.A.1
Soo Hong, B.2
Park, H.W.3
Vedadi, M.4
-
36
-
-
77953566909
-
Quantitative determination of protein stability and ligand binding using a green fluorescent protein reporter system
-
Moreau M.J., Morin I., Schaeffer P.M. Quantitative determination of protein stability and ligand binding using a green fluorescent protein reporter system. Mol Biosyst 2010, 6:1285-1292.
-
(2010)
Mol Biosyst
, vol.6
, pp. 1285-1292
-
-
Moreau, M.J.1
Morin, I.2
Schaeffer, P.M.3
-
37
-
-
18244380348
-
High-density miniaturized thermal shift assays as a general strategy for drug discovery
-
Pantoliano M.W., Petrella E.C., Kwasnoski J.D., Lobanov V.S., Myslik J., Graf E., Carver T., Asel E., Springer B.A., Lane P., et al. High-density miniaturized thermal shift assays as a general strategy for drug discovery. J Biomol Screen 2001, 6:429-440.
-
(2001)
J Biomol Screen
, vol.6
, pp. 429-440
-
-
Pantoliano, M.W.1
Petrella, E.C.2
Kwasnoski, J.D.3
Lobanov, V.S.4
Myslik, J.5
Graf, E.6
Carver, T.7
Asel, E.8
Springer, B.A.9
Lane, P.10
-
38
-
-
33748929006
-
Thermofluor-based high-throughput stability optimization of proteins for structural studies
-
Ericsson U.B., Hallberg B.M., Detitta G.T., Dekker N., Nordlund P. Thermofluor-based high-throughput stability optimization of proteins for structural studies. Anal Biochem 2006, 357:289-298.
-
(2006)
Anal Biochem
, vol.357
, pp. 289-298
-
-
Ericsson, U.B.1
Hallberg, B.M.2
Detitta, G.T.3
Dekker, N.4
Nordlund, P.5
-
39
-
-
33750470057
-
Chemical screening methods to identify ligands that promote protein stability, protein crystallization, and structure determination
-
Vedadi M., Niesen F.H., Allali-Hassani A., Fedorov O.Y., Finerty P.J., Wasney G.A., Yeung R., Arrowsmith C., Ball L.J., Berglund H., et al. Chemical screening methods to identify ligands that promote protein stability, protein crystallization, and structure determination. Proc Natl Acad Sci USA 2006, 103:15835-15840.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 15835-15840
-
-
Vedadi, M.1
Niesen, F.H.2
Allali-Hassani, A.3
Fedorov, O.Y.4
Finerty, P.J.5
Wasney, G.A.6
Yeung, R.7
Arrowsmith, C.8
Ball, L.J.9
Berglund, H.10
-
40
-
-
67849129183
-
High-throughput thermal scanning: a general, rapid dye-binding thermal shift screen for protein engineering
-
Lavinder J.J., Hari S.B., Sullivan B.J., Magliery T.J. High-throughput thermal scanning: a general, rapid dye-binding thermal shift screen for protein engineering. J Am Chem Soc 2009, 131:3794-3795.
-
(2009)
J Am Chem Soc
, vol.131
, pp. 3794-3795
-
-
Lavinder, J.J.1
Hari, S.B.2
Sullivan, B.J.3
Magliery, T.J.4
-
41
-
-
78650485354
-
Thermodynamic analysis of ligand-induced changes in protein thermal unfolding applied to high-throughput determination of ligand affinities with extrinsic fluorescent dyes
-
Layton C.J., Hellinga H.W. Thermodynamic analysis of ligand-induced changes in protein thermal unfolding applied to high-throughput determination of ligand affinities with extrinsic fluorescent dyes. Biochemistry 2010, 49:10831-10841.
-
(2010)
Biochemistry
, vol.49
, pp. 10831-10841
-
-
Layton, C.J.1
Hellinga, H.W.2
-
42
-
-
33847324003
-
Protein fabrication automation
-
Cox J.C., Lape J., Sayed M.A., Hellinga H.W. Protein fabrication automation. Protein Sci 2007, 16:379-390.
-
(2007)
Protein Sci
, vol.16
, pp. 379-390
-
-
Cox, J.C.1
Lape, J.2
Sayed, M.A.3
Hellinga, H.W.4
-
43
-
-
78650021707
-
Scalable gene synthesis by selective amplification of DNA pools from high-fidelity microchips
-
Kosuri S., Eroshenko N., Leproust E.M., Super M., Way J., Li J.B., Church G.M. Scalable gene synthesis by selective amplification of DNA pools from high-fidelity microchips. Nat Biotechnol 2010, 28:1295-1299.
-
(2010)
Nat Biotechnol
, vol.28
, pp. 1295-1299
-
-
Kosuri, S.1
Eroshenko, N.2
Leproust, E.M.3
Super, M.4
Way, J.5
Li, J.B.6
Church, G.M.7
-
44
-
-
1142269592
-
Rapid expression and purification of 100 nmol quantities of active protein using cell-free protein synthesis
-
Jewett M.C., Swartz J.R. Rapid expression and purification of 100 nmol quantities of active protein using cell-free protein synthesis. Biotechnol Prog 2004, 20:102-109.
-
(2004)
Biotechnol Prog
, vol.20
, pp. 102-109
-
-
Jewett, M.C.1
Swartz, J.R.2
-
45
-
-
66249144426
-
The structure and function of G-protein-coupled receptors
-
Rosenbaum D.M., Rasmussen S.G., Kobilka B.K. The structure and function of G-protein-coupled receptors. Nature 2009, 459:356-363.
-
(2009)
Nature
, vol.459
, pp. 356-363
-
-
Rosenbaum, D.M.1
Rasmussen, S.G.2
Kobilka, B.K.3
-
46
-
-
40049099087
-
Microscale fluorescent thermal stability assay for membrane proteins
-
Alexandrov A.I., Mileni M., Chien E.Y., Hanson M.A., Stevens R.C. Microscale fluorescent thermal stability assay for membrane proteins. Structure 2008, 16:351-359.
-
(2008)
Structure
, vol.16
, pp. 351-359
-
-
Alexandrov, A.I.1
Mileni, M.2
Chien, E.Y.3
Hanson, M.A.4
Stevens, R.C.5
-
47
-
-
77951645706
-
LCP-Tm: an assay to measure and understand stability of membrane proteins in a membrane environment
-
Liu W., Hanson M.A., Stevens R.C., Cherezov V. LCP-Tm: an assay to measure and understand stability of membrane proteins in a membrane environment. Biophys J 2010, 98:1539-1548.
-
(2010)
Biophys J
, vol.98
, pp. 1539-1548
-
-
Liu, W.1
Hanson, M.A.2
Stevens, R.C.3
Cherezov, V.4
-
48
-
-
57049083012
-
A high-throughput assay of membrane protein stability
-
Postis V.L., Deacon S.E., Roach P.C., Wright G.S., Xia X., Ingram J.C., Hadden J.M., Henderson P.J., Phillips S.E., McPherson M.J., et al. A high-throughput assay of membrane protein stability. Mol Membr Biol 2008, 25:617-624.
-
(2008)
Mol Membr Biol
, vol.25
, pp. 617-624
-
-
Postis, V.L.1
Deacon, S.E.2
Roach, P.C.3
Wright, G.S.4
Xia, X.5
Ingram, J.C.6
Hadden, J.M.7
Henderson, P.J.8
Phillips, S.E.9
McPherson, M.J.10
-
49
-
-
33646252015
-
Rapid and simple protein-stability screens: application to membrane proteins
-
Yeh A.P., McMillan A., Stowell M.H. Rapid and simple protein-stability screens: application to membrane proteins. Acta Crystallogr D Biol Crystallogr 2006, 62:451-457.
-
(2006)
Acta Crystallogr D Biol Crystallogr
, vol.62
, pp. 451-457
-
-
Yeh, A.P.1
McMillan, A.2
Stowell, M.H.3
-
50
-
-
77949789023
-
High throughput thermostability screening of monoclonal antibody formulations
-
He F., Hogan S., Latypov R.F., Narhi L.O., Razinkov V.I. High throughput thermostability screening of monoclonal antibody formulations. J Pharm Sci 2010, 99:1707-1720.
-
(2010)
J Pharm Sci
, vol.99
, pp. 1707-1720
-
-
He, F.1
Hogan, S.2
Latypov, R.F.3
Narhi, L.O.4
Razinkov, V.I.5
-
51
-
-
79957995850
-
Formulation development of therapeutic monoclonal antibodies using high-throughput fluorescence and static light scattering techniques: role of conformational and colloidal stability
-
Goldberg D.S., Bishop S.M., Shah A.U., Sathish H.A. Formulation development of therapeutic monoclonal antibodies using high-throughput fluorescence and static light scattering techniques: role of conformational and colloidal stability. J Pharm Sci 2010.
-
(2010)
J Pharm Sci
-
-
Goldberg, D.S.1
Bishop, S.M.2
Shah, A.U.3
Sathish, H.A.4
-
52
-
-
77955976111
-
Stability engineering of scFvs for the development of bispecific and multivalent antibodies
-
Miller B.R., Demarest S.J., Lugovskoy A., Huang F., Wu X., Snyder W.B., Croner L.J., Wang N., Amatucci A., Michaelson J.S., et al. Stability engineering of scFvs for the development of bispecific and multivalent antibodies. Protein Eng Des Sel 2010, 23:549-557.
-
(2010)
Protein Eng Des Sel
, vol.23
, pp. 549-557
-
-
Miller, B.R.1
Demarest, S.J.2
Lugovskoy, A.3
Huang, F.4
Wu, X.5
Snyder, W.B.6
Croner, L.J.7
Wang, N.8
Amatucci, A.9
Michaelson, J.S.10
-
53
-
-
51249120701
-
Free sulfhydryl measurement as an indicator of antibody stability
-
Lacy E.R., Baker M., Brigham-Burke M. Free sulfhydryl measurement as an indicator of antibody stability. Anal Biochem 2008, 382:66-68.
-
(2008)
Anal Biochem
, vol.382
, pp. 66-68
-
-
Lacy, E.R.1
Baker, M.2
Brigham-Burke, M.3
-
54
-
-
0028111743
-
Sequence statistics reliably predict stabilizing mutations in a protein domain
-
Steipe B., Schiller B., Pluckthun A., Steinbacher S. Sequence statistics reliably predict stabilizing mutations in a protein domain. J Mol Biol 1994, 240:188-192.
-
(1994)
J Mol Biol
, vol.240
, pp. 188-192
-
-
Steipe, B.1
Schiller, B.2
Pluckthun, A.3
Steinbacher, S.4
-
55
-
-
0032718607
-
Intrabody construction and expression III: engineering hyperstable V(H) domains
-
Wirtz P., Steipe B. Intrabody construction and expression III: engineering hyperstable V(H) domains. Protein Sci 1999, 8:2245-2250.
-
(1999)
Protein Sci
, vol.8
, pp. 2245-2250
-
-
Wirtz, P.1
Steipe, B.2
-
56
-
-
0036271498
-
The consensus concept for thermostability engineering of proteins: further proof of concept
-
Lehmann M., Loch C., Middendorf A., Studer D., Lassen S.F., Pasamontes L., van Loon A.P., Wyss M. The consensus concept for thermostability engineering of proteins: further proof of concept. Protein Eng 2002, 15:403-411.
-
(2002)
Protein Eng
, vol.15
, pp. 403-411
-
-
Lehmann, M.1
Loch, C.2
Middendorf, A.3
Studer, D.4
Lassen, S.F.5
Pasamontes, L.6
van Loon, A.P.7
Wyss, M.8
-
57
-
-
0034731381
-
The consensus concept for thermostability engineering of proteins
-
Lehmann M., Pasamontes L., Lassen S.F., Wyss M. The consensus concept for thermostability engineering of proteins. Biochim Biophys Acta 2000, 1543:408-415.
-
(2000)
Biochim Biophys Acta
, vol.1543
, pp. 408-415
-
-
Lehmann, M.1
Pasamontes, L.2
Lassen, S.F.3
Wyss, M.4
-
58
-
-
0037452697
-
Designed to be stable: crystal structure of a consensus ankyrin repeat protein
-
Kohl A., Binz H.K., Forrer P., Stumpp M.T., Pluckthun A., Grutter M.G. Designed to be stable: crystal structure of a consensus ankyrin repeat protein. Proc Natl Acad Sci USA 2003, 100:1700-1705.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 1700-1705
-
-
Kohl, A.1
Binz, H.K.2
Forrer, P.3
Stumpp, M.T.4
Pluckthun, A.5
Grutter, M.G.6
-
59
-
-
18744380008
-
Consensus-derived structural determinants of the ankyrin repeat motif
-
Mosavi L.K., Minor D.L., Peng Z.Y. Consensus-derived structural determinants of the ankyrin repeat motif. Proc Natl Acad Sci USA 2002, 99:16029-16034.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 16029-16034
-
-
Mosavi, L.K.1
Minor, D.L.2
Peng, Z.Y.3
-
60
-
-
0037648552
-
Design of stable alpha-helical arrays from an idealized TPR motif
-
Main E.R., Xiong Y., Cocco M.J., D'Andrea L., Regan L. Design of stable alpha-helical arrays from an idealized TPR motif. Structure 2003, 11:497-508.
-
(2003)
Structure
, vol.11
, pp. 497-508
-
-
Main, E.R.1
Xiong, Y.2
Cocco, M.J.3
D'Andrea, L.4
Regan, L.5
-
61
-
-
77954762143
-
Consensus protein design without phylogenetic bias
-
Jackel C., Bloom J.D., Kast P., Arnold F.H., Hilvert D. Consensus protein design without phylogenetic bias. J Mol Biol 2010, 399:541-546.
-
(2010)
J Mol Biol
, vol.399
, pp. 541-546
-
-
Jackel, C.1
Bloom, J.D.2
Kast, P.3
Arnold, F.H.4
Hilvert, D.5
-
62
-
-
29144522906
-
Designing thermostable proteins: ancestral mutants of 3-isopropylmalate dehydrogenase designed by using a phylogenetic tree
-
Watanabe K., Ohkuri T., Yokobori S., Yamagishi A. Designing thermostable proteins: ancestral mutants of 3-isopropylmalate dehydrogenase designed by using a phylogenetic tree. J Mol Biol 2006, 355:664-674.
-
(2006)
J Mol Biol
, vol.355
, pp. 664-674
-
-
Watanabe, K.1
Ohkuri, T.2
Yokobori, S.3
Yamagishi, A.4
-
63
-
-
67650507983
-
Directed evolution of serum paraoxonase PON3 by family shuffling and ancestor/consensus mutagenesis, and its biochemical characterization
-
Khersonsky O., Rosenblat M., Toker L., Yacobson S., Hugenmatter A., Silman I., Sussman J.L., Aviram M., Tawfik D.S. Directed evolution of serum paraoxonase PON3 by family shuffling and ancestor/consensus mutagenesis, and its biochemical characterization. Biochemistry 2009, 48:6644-6654.
-
(2009)
Biochemistry
, vol.48
, pp. 6644-6654
-
-
Khersonsky, O.1
Rosenblat, M.2
Toker, L.3
Yacobson, S.4
Hugenmatter, A.5
Silman, I.6
Sussman, J.L.7
Aviram, M.8
Tawfik, D.S.9
-
64
-
-
0033536602
-
Evolutionarily conserved pathways of energetic connectivity in protein families
-
Lockless S.W., Ranganathan R. Evolutionarily conserved pathways of energetic connectivity in protein families. Science 1999, 286:295-299.
-
(1999)
Science
, vol.286
, pp. 295-299
-
-
Lockless, S.W.1
Ranganathan, R.2
-
65
-
-
25644452032
-
Evolutionary information for specifying a protein fold
-
Socolich M., Lockless S.W., Russ W.P., Lee H., Gardner K.H., Ranganathan R. Evolutionary information for specifying a protein fold. Nature 2005, 437:512-518.
-
(2005)
Nature
, vol.437
, pp. 512-518
-
-
Socolich, M.1
Lockless, S.W.2
Russ, W.P.3
Lee, H.4
Gardner, K.H.5
Ranganathan, R.6
-
66
-
-
0345492351
-
Allosteric determinants in guanine nucleotide-binding proteins
-
Hatley M.E., Lockless S.W., Gibson S.K., Gilman A.G., Ranganathan R. Allosteric determinants in guanine nucleotide-binding proteins. Proc Natl Acad Sci USA 2003, 100:14445-14450.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 14445-14450
-
-
Hatley, M.E.1
Lockless, S.W.2
Gibson, S.K.3
Gilman, A.G.4
Ranganathan, R.5
-
67
-
-
54249105941
-
Surface sites for engineering allosteric control in proteins
-
Lee J., Natarajan M., Nashine V.C., Socolich M., Vo T., Russ W.P., Benkovic S.J., Ranganathan R. Surface sites for engineering allosteric control in proteins. Science 2008, 322:438-442.
-
(2008)
Science
, vol.322
, pp. 438-442
-
-
Lee, J.1
Natarajan, M.2
Nashine, V.C.3
Socolich, M.4
Vo, T.5
Russ, W.P.6
Benkovic, S.J.7
Ranganathan, R.8
-
68
-
-
77957274298
-
An interdomain sector mediating allostery in Hsp70 molecular chaperones
-
Smock R.G., Rivoire O., Russ W.P., Swain J.F., Leibler S., Ranganathan R., Gierasch L.M. An interdomain sector mediating allostery in Hsp70 molecular chaperones. Mol Syst Biol 2010, 6:414.
-
(2010)
Mol Syst Biol
, vol.6
, pp. 414
-
-
Smock, R.G.1
Rivoire, O.2
Russ, W.P.3
Swain, J.F.4
Leibler, S.5
Ranganathan, R.6
Gierasch, L.M.7
-
69
-
-
68749107059
-
Protein sectors: evolutionary units of three-dimensional structure
-
Halabi N., Rivoire O., Leibler S., Ranganathan R. Protein sectors: evolutionary units of three-dimensional structure. Cell 2009, 138:774-786.
-
(2009)
Cell
, vol.138
, pp. 774-786
-
-
Halabi, N.1
Rivoire, O.2
Leibler, S.3
Ranganathan, R.4
-
70
-
-
4744365127
-
Beyond consensus: statistical free energies reveal hidden interactions in the design of a TPR motif
-
Magliery T.J., Regan L. Beyond consensus: statistical free energies reveal hidden interactions in the design of a TPR motif. J Mol Biol 2004, 343:731-745.
-
(2004)
J Mol Biol
, vol.343
, pp. 731-745
-
-
Magliery, T.J.1
Regan, L.2
-
71
-
-
27644527039
-
Sequence variation in ligand binding sites in proteins
-
Magliery T.J., Regan L. Sequence variation in ligand binding sites in proteins. BMC Bioinformatics 2005, 6:240.
-
(2005)
BMC Bioinformatics
, vol.6
, pp. 240
-
-
Magliery, T.J.1
Regan, L.2
|