High-density miniaturized thermal shift assays as a general strategy for drug discovery

Journal of Biomolecular Screening

Volumn 6, Issue 6, 2001, Pages 429-440

  Pantoliano, Michael W ^a   Petrella, Eugene C ^b   Kwasnoski, Joseph D ^b   Lobanov, Victor S ^b   Myslik, James ^b   Graf, Edward ^b   Carver, Ted ^b   Asel, Eric ^b   Springer, Barry A ^b   Lane, Pamela ^b   Salemme, F R ^b  

^a MILLENNIUM PHARMACEUTICALS INC   (United States)

^b JOHNSON AND JOHNSON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NEW DRUG;

ARTICLE; ASSAY; COMBINATORIAL CHEMISTRY; DRUG SCREENING; GENOMICS; LIGAND BINDING; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STABILITY; VALIDATION PROCESS;

ESTROGEN RECEPTOR ALPHA; FLUORESCENT DYES; HUMANS; LIGANDS; MINIATURIZATION; PHARMACEUTICAL PREPARATIONS; PROTEINS; RECEPTORS, ESTROGEN; REPRODUCIBILITY OF RESULTS; TEMPERATURE;

HARNESS;

EID: 18244380348     PISSN: 10870571     EISSN: None     Source Type: Journal    
DOI: 10.1089/108705701753364922     Document Type: Article

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