Experimental library screening demonstrates the successful application of computational protein design to large structural ensembles

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 46, 2010, Pages 19838-19843

  Allen, Benjamin D ^a   Nisthal, Alex ^b   Mayo, Stephen L ^b  

^a California Institute of Technology   (United States)

^b CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

High throughput stability determination; Library design; Molecular dynamics; NMR ensemble; Protein engineering

Indexed keywords

COMBINATORIAL LIBRARY; CONFERENCE PAPER; EXPERIMENTAL DESIGN; HIGH THROUGHPUT SCREENING; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN STABILITY; SIMULATION; THERMODYNAMICS;

EID: 78650566901     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1012985107     Document Type: Article

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