The DNA damage response kinases DNA-dependent protein kinase (DNA-PK) and ataxia telangiectasia mutated (ATM) are stimulated by bulky adduct-containing DNA

Journal of Biological Chemistry

Volumn 286, Issue 22, 2011, Pages 19237-19246

  Kemp, Michael G ^a   Lindsey Boltz, Laura A ^a   Sancar, Aziz ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATAXIA-TELANGIECTASIA MUTATED; ATM AND RAD3-RELATED; BENZO(A)PYRENE; BIOCHEMICAL MECHANISMS; CELL-FREE SYSTEM; CHEMOTHERAPEUTIC AGENTS; DNA ADDUCTS; DNA DAMAGE RESPONSE; DNA DAMAGES; DNA-DEPENDENT PROTEIN KINASE; HUMAN CELLS; IN-VITRO; IN-VITRO ASSAYS; MAMMALIAN CELLS; NUCLEAR EXTRACTS; PLASMID DNA; SIGNALING PATHWAYS;

AUTOMATIC TELLER MACHINES; ENZYMES; INTERNET PROTOCOLS; MAMMALS; PHYSIOLOGICAL MODELS; PROTEINS; SIGNALING;

DNA;

ATM PROTEIN; ATR PROTEIN; CHECKPOINT KINASE 1; DIHYDROXYBENZO[A]PYRENE OXIDE; DNA DEPENDENT PROTEIN KINASE; N ACETOXY N (2 FLUORENYL)ACETAMIDE; PLASMID DNA; PROTEIN P53;

ANIMAL CELL; ARTICLE; CELL ASSAY; CELL FREE SYSTEM; CONTROLLED STUDY; DNA ADDUCT; DNA DAMAGE; ENZYME ACTIVATION; ENZYME PURIFICATION; IN VITRO STUDY; MAMMAL CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ACETOXYACETYLAMINOFLUORENE; ALKYLATING AGENTS; ANIMALS; BENZO(A)PYRENE; CELL CYCLE PROTEINS; CHO CELLS; CRICETINAE; CRICETULUS; DNA ADDUCTS; DNA DAMAGE; DNA-ACTIVATED PROTEIN KINASE; DNA-BINDING PROTEINS; HUMANS; NUCLEAR PROTEINS; PHOSPHORYLATION; PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS;

ATAXIA TELANGIECTASIA; MAMMALIA;

EID: 79957616243     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.235036     Document Type: Article

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