Gastrointestinal contents in fasted state and post-lipid ingestion: In vivo measurements and in vitro models for studying oral drug delivery

Journal of Controlled Release

Volumn 151, Issue 2, 2011, Pages 110-122

  Di Maio, Selena ^a   Carrier, Rebecca L ^a  

^a Northeastern University   (United States)

Author keywords

Bio relevant medium; Colloids; Dissolution; In vitro lipolysis; Lipids; Oral drug delivery

Indexed keywords

BIO-RELEVANT MEDIUM; DIGESTION PROCESS; DISSOLUTION TESTING; DRUG DISSOLUTION; FOOD INTAKE; GASTROINTESTINAL TRACT; GI TRACT; IN-VITRO; IN-VIVO; IN-VIVO MEASUREMENT; ORAL DRUG DELIVERY; PHYSICOCHEMICAL PROPERTY;

ABSORPTION; BIOCHEMISTRY; DISSOLUTION; DRUG DELIVERY; LIPIDS; PHYSIOLOGICAL MODELS;

DRUG INTERACTIONS;

BILE ACID; BUFFER; CALCIUM ION; LONG CHAIN TRIACYLGLYCEROL; MONOACYLGLYCEROL; PHOSPHOLIPID; TAUROCHOLIC ACID; TAURODEOXYCHOLIC ACID;

COLLOID; DIET RESTRICTION; DIGESTION; DRUG TRANSPORT; ELECTRON SPIN RESONANCE; FAT INTAKE; HIGH PERFORMANCE THIN LAYER CHROMATOGRAPHY; IN VITRO STUDY; IN VIVO STUDY; INTESTINE ABSORPTION; INTESTINE FLUID; LIPID METABOLISM; LIPOLYSIS; OSMOLALITY; PEPSIN SECRETION; PH; PRIORITY JOURNAL; QUALITY CONTROL; REVIEW; STOMACH EMPTYING; STOMACH JUICE; SURFACE TENSION;

ADMINISTRATION, ORAL; ANIMALS; BIOLOGICAL AVAILABILITY; DRUG DELIVERY SYSTEMS; FASTING; GASTROINTESTINAL CONTENTS; HUMANS; INTESTINAL ABSORPTION; LIPID METABOLISM; LIPIDS; MODELS, BIOLOGICAL; PHARMACEUTICAL PREPARATIONS;

EID: 79956090650     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2010.11.034     Document Type: Review

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