Forecasting the in vivo performance of four low solubility drugs from their in vitro dissolution data

Pharmaceutical Research

Volumn 16, Issue 12, 1999, Pages 1876-1882

  Nicolaides, Eleftheria ^a   Galia, Eric ^b,c   Efthymiopoulos, Constantin ^d,e   Dressman, Jennifer B ^b   Reppas, Christos ^a  

^a UNIVERSITY OF ATHENS   (Greece)

^b GOETHE UNIVERSITY   (Germany)

^c ERWEKA GmbH   (Germany)

^d GLAXOSMITHKLINE   (United Kingdom)

^e Serono International SA   (Switzerland)

Author keywords

Atovaquone; Dissolution; Low solubility drugs; Sanfetrinem cilexetil; Troglitazone

Indexed keywords

1,4 NAPHTHOQUINONE DERIVATIVE; ANTHRACENE DERIVATIVE; ATOVAQUONE; BILE SALT; PHOSPHATIDYLCHOLINE; POTASSIUM CHLORIDE; POTASSIUM DIHYDROGEN PHOSPHATE; SANFETRINEM CILEXETIL; TAUROCHOLIC ACID; TROGLITAZONE; WATER;

ARTICLE; DIET RESTRICTION; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG FORMULATION; DRUG SOLUBILITY; FOOD DRUG INTERACTION; FOOD INTAKE; FORECASTING; HUMAN; LIPOPHILICITY; MILK; POWDER; PREDICTION; PRIORITY JOURNAL;

EID: 0033452575     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1018959511323     Document Type: Article

References (20)

1. M. C. Meyer, A. B. Straughn, R. M. Mhatre, V. P. Shah, R. L. Williams, and L. J. Lesko. Lack of in vivo/in vitro correlations for 50 mg and 250 mg primidone tablets. Pharm. Res. 15:1085-1089 (1998)
2. J. B. Dressman, G. L. Amidon, C. Reppas, and V. P. Shah. Dissolution as a prognostic tool for oral drug absorption: immediate release dosage forms. Pharm. Res. 15:11-22 (1998)
3. E. Galia, E. Nicolaides, D. Hörter, R. Löbenberg, C. Reppas, and J. B. Dressman. Evaluation of various dissolution media for predicting in vivo performance of class I and class II drugs. Pharm. Res. 15:698-705 (1998)
4. M. D. Johnson, L. K. Campbell, and R. K. Campbell. Troglitazone: review and assessment of its role in the treatment of patients with impaired glucose tolerance and diabetes mellitus. Ann. Pharmacother. 32:337-348 (1998)
5. C. M. Spencer, and K. L. Goa. Atovaquone. A review of its pharmacological properties and therapeutic efficacy in opportunistic infections. Drugs 50:176-196 (1995)
6. S. Tamura, S. Miyazaki, K. Tateda, A. Ohno, Y. Ishii, T. Matsumoto, N. Furuya, and K. Yamaguchi. In vivo antibacterial activities of sanfetrinem cilexetil, a new oral tricyclic antibiotic. Antimicrob. Agents Chemother. 42:1858-1861 (1998)
7. L. Iavarone, M. Bottacini, F. Pugnaghi, C. Morandini, and P. Grossi. Sanfetrinem and sanfetrinem-cilexetil: disposition in rat and dog. Xenobiotica 27:693-709 (1997)
8. G. L. Amidon, H. Lenncrnäs, V. P. Shah, and J. R. A. Crison. Theoretical basis for a biopharmaceutics drug classification: the correlation of in vitro drug product dissolution and in vivo bioavailability. Pharm. Res. 12:413-420 (1995)
9. P. Macheras, M. Koupparis, and C. Tsaprounis. Drug dissolution studies in milk using the automated flow injection serial dynamic dialysis technique. Int. J. Pharm. 33:125-136 (1986)
10. P. E. Macheras, M. A. Koupparis, and S. G. Antimisiaris. Drug binding and solubility in milk Pharm. Res. 7:537-541 (1990)
11. Y. Fu, C. Shen, T. Fujita, and C. S. Foote. Photooxidation of troglitazone, a new antidiabetic drug. Photochem. Photobiol. 63:615-620 (1996)
12. nd Edition), Macmillan Press Ltd., London, 1988
13. M. A. Young, S. Lettis, and R. Eastmond. Improvement in the gastrointestinal absorption of troglitazone when taken with, or shortly after food. Br. J. Clin. Pharmacol. 45:31-35 (1998)
14. P. E. Rolan, A. J. Mercer, B. C. Weatherley, T. Holdich, H. Meire, R. W. Peck, G. Ridout, and J. Posner. Examination of some factors responsible for a food-induced increase in absorption of atovaquone. Br. J. Clin. Pharmacol. 37:13-20 (1994)
15. E. Galia, C. Hoth, N. Künnen, A. Nöske, R. Schulte, S. Stein, M. Wunderlich, J. Horton, and J. B. Dressman. Comparative in vitro dissolution study of various albendazole products. PharmSci. (Suppl.) 1:S-491 (1998)
16. P. Walstra, R. Jennes, and H.T. Badings. Dairy chemistry and physics, John Wiley and Sons, New York, 1984
17. J. Borovicka, W. Schwizer, C. Mettraux, C. Kreiss, B. Remy, K. Asal, J. B. Jansen, I. Douchet, R. Verger, and M. Fried. Regulation of gastric and pancreatic lipase secretion by CCK and cholinergic mechanisms in humans. Am. J. Physiol. 273:G374-G380 (1997)
18. T. Ono, Y. Takagi, and I. Kunishi. Casein phosphopeptides from casein micelles by successive digestion with pepsin and trypsin. Biosci. Biotechnol. Biochem. 62:16-21 (1998)
19. G. Miranda and J. P. Pelissier. Kinetic studies of in vivo digestion of bovine unheated skim-milk proteins in the rat stomach. J. Dairy Res. 50:27-36 (1983)
20. J. S. Fordtran and T. Locklear. Ionic constituents and osmolarity of gastric and small intestinal fluids after eating. Am. J. Dig. Dis. 11:503-521 (1966)