Estimation of the increase in solubility of drugs as a function of bile salt concentration

Pharmaceutical Research

Volumn 13, Issue 1, 1996, Pages 163-167

  Mithani, Sabena D ^a   Bakatselou, Vassiliki ^a,b   TenHoor, Christopher N ^a,c   Dressman, Jennifer B ^a,d  

^a UNIVERSITY OF MICHIGAN   (United States)

^b Janssen Pharmaceuticals   (Greece)

^c SANOFI   (France)

^d GOETHE UNIVERSITY   (Germany)

Author keywords

Bile salts; Partition coefficient; Poorly soluble drugs; Sodium taurocholate; Solubility

Indexed keywords

BETAMETHASONE; BETAMETHASONE VALERATE; BILE SALT; CYCLOSPORIN A; DANAZOL; DEXAMETHASONE; DIAZEPAM; GRISEOFULVIN; HYDROCORTISONE; PENTAZOCINE; PHENYTOIN; TAUROCHOLIC ACID; TRIAMCINOLONE;

ARTICLE; DRUG SOLUBILITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IONIC STRENGTH; MODEL; PARTITION COEFFICIENT; PREDICTION; PRIORITY JOURNAL; SOLUBILIZATION;

BILE ACIDS AND SALTS; CHEMISTRY, PHYSICAL; CHOLAGOGUES AND CHOLERETICS; CYCLOSPORINE; DIAZEPAM; FASTING; FOOD; GRISEOFULVIN; INTESTINAL ABSORPTION; MODELS, CHEMICAL; PENTAZOCINE; PHENYTOIN; SOLUBILITY; STEROIDS; TAUROCHOLIC ACID;

EID: 0030003789     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1016062224568     Document Type: Article

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