Whole genome siRNA cell-based screen links mitochondria to Akt signaling network through uncoupling of electron transport chain

Molecular Biology of the Cell

Volumn 22, Issue 10, 2011, Pages 1791-1805

  Senapedis, William T ^a   Kennedy, Caleb J ^a   Boyle, Patrick M ^a   Silver, Pamela A ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FREE RADICAL; PROTEIN KINASE B; PROTEIN UCP5; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE 1; SUPEROXIDE; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR FKHR; UNCLASSIFIED DRUG; UNCOUPLING PROTEIN;

ARTICLE; ELECTRON TRANSPORT; ENZYME ACTIVITY; FOCAL ADHESION; GENE EXPRESSION; GENE LIBRARY; GENE TARGETING; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL RESPIRATION; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN LOCALIZATION; PROTEIN METABOLISM; PROTEIN MODIFICATION; SIGNAL TRANSDUCTION;

ACTIVE TRANSPORT, CELL NUCLEUS; ADENOSINE TRIPHOSPHATE; CELL LINE; ELECTRON TRANSPORT CHAIN COMPLEX PROTEINS; FORKHEAD TRANSCRIPTION FACTORS; GENOME-WIDE ASSOCIATION STUDY; HUMANS; ION CHANNELS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MEMBRANE TRANSPORT PROTEINS; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; MITOGEN-ACTIVATED PROTEIN KINASE 8; NERVE TISSUE PROTEINS; OXIDATIVE PHOSPHORYLATION; PROTEIN TRANSPORT; PROTO-ONCOGENE PROTEINS C-AKT; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION;

EID: 79955978279     PISSN: 10591524     EISSN: 19394586     Source Type: Journal    
DOI: 10.1091/mbc.E10-10-0854     Document Type: Article

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