Unraveling the metabolism of HEK-293 cells using lactate isotopomer analysis

Bioprocess and Biosystems Engineering

Volumn 34, Issue 3, 2011, Pages 263-273

  Henry, Olivier ^a   Jolicoeur, Mario ^a   Kamen, Amine ^b  

^a ÉCOLE POLYTECHNIQUE DE MONTRÉAL   (Canada)

^b NATIONAL RESEARCH COUNCIL CANADA   (Canada)

Author keywords

13C metabolic flux analysis; HEK 293 cells; Isotopic tracer; Metabolism

Indexed keywords

CARBON METABOLISM; CELL LINES; CYTOSOLIC; ENERGY PRODUCTIONS; FLUX ANALYSIS; HEK-293; HEK-293 CELLS; HUMAN CELL LINES; INTRACELLULAR PATHWAYS; ISOTOPIC TRACER; ISOTOPOMER DISTRIBUTIONS; MALIC ENZYMES; METABOLIC MODELS; PROCESS LEVELS; RECOMBINANT PROTEIN; TCA CYCLE; TRANSIENT TRANSFECTION; VIRAL VECTORS;

AMINO ACIDS; BIOCHEMISTRY; CELL CULTURE; GLUCOSE; ISOMERS; ISOTOPES; PHYSIOLOGY; PROTEINS;

METABOLISM;

CARBON 13; GLUTAMINE; LACTIC ACID; PENTOSE PHOSPHATE; TRICARBOXYLIC ACID;

ARTICLE; CARBON METABOLISM; CELL GROWTH; CELL LABELING; CELL METABOLISM; CELL STRAIN HEK293; CELL TRANSPORT; CELLULAR DISTRIBUTION; CONTROLLED STUDY; EMBRYO; ENERGY YIELD; HUMAN; HUMAN CELL; LIPOGENESIS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLIC BALANCE; PRIORITY JOURNAL;

ACETYL COENZYME A; AMINO ACIDS; CARBON; CARBON ISOTOPES; CELL LINE; CELL SURVIVAL; CHROMATOGRAPHY, LIQUID; CITRIC ACID CYCLE; GLUCOSE; GLUTAMINE; HEK293 CELLS; HUMANS; LACTIC ACID; LIPIDS; MAGNETIC RESONANCE SPECTROSCOPY; MALATES; OXALOACETATE; PENTOSE PHOSPHATE PATHWAY;

EID: 79955939126     PISSN: 16157591     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00449-010-0468-9     Document Type: Article

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