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Volumn 17, Issue 11, 2011, Pages 1383-1399

Molecular cross-talk between helicobacter pylori and human gastric mucosa

Author keywords

Bacterial virulence factors; CagA; Gastric diseases; Gastric mucosa; Helicobacter pylori; Pathogen host interaction; VacA

Indexed keywords

CAGA PROTEIN; TOLL LIKE RECEPTOR 4; VACUOLATING TOXIN; VIRULENCE FACTOR;

EID: 79955937307     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.v17.i11.1383     Document Type: Article
Times cited : (47)

References (130)
  • 1
    • 0033807944 scopus 로고    scopus 로고
    • Recent developments in the epidemiology of Helicobacter pylori
    • Everhart JE. Recent developments in the epidemiology of Helicobacter pylori. Gastroenterol Clin North Am 2000; 29: 559-578
    • (2000) Gastroenterol Clin North Am , vol.29 , pp. 559-578
    • Everhart, J.E.1
  • 2
    • 0033188147 scopus 로고    scopus 로고
    • Molecular response of gastric epithelial cells to Helicobacter pylori-induced cell damage
    • Zarrilli R, Ricci V, Romano M. Molecular response of gastric epithelial cells to Helicobacter pylori-induced cell damage. Cell Microbiol 1999; 1: 93-99
    • (1999) Cell Microbiol , vol.1 , pp. 93-99
    • Zarrilli, R.1    Ricci, V.2    Romano, M.3
  • 3
    • 77953152285 scopus 로고    scopus 로고
    • Epidemiology of gastrointestinal and liver tumors
    • Herszényi L, Tulassay Z. Epidemiology of gastrointestinal and liver tumors. Eur Rev Med Pharmacol Sci 2010; 14: 249-258
    • (2010) Eur Rev Med Pharmacol Sci , vol.14 , pp. 249-258
    • Herszényi, L.1    Tulassay, Z.2
  • 4
    • 70449096096 scopus 로고    scopus 로고
    • Helicobacter pylori and gastric adenocarcinoma
    • Herrera V, Parsonnet J. Helicobacter pylori and gastric adenocarcinoma. Clin Microbiol Infect 2009; 15: 971-976
    • (2009) Clin Microbiol Infect , vol.15 , pp. 971-976
    • Herrera, V.1    Parsonnet, J.2
  • 6
    • 0036370334 scopus 로고    scopus 로고
    • Helicobacter pylori and gastrointestinal tract adenocarcinomas
    • Peek RM Jr, Blaser MJ. Helicobacter pylori and gastrointestinal tract adenocarcinomas. Nat Rev Cancer 2002; 2: 28-37
    • (2002) Nat Rev Cancer , vol.2 , pp. 28-37
    • Peek Jr., R.M.1    Blaser, M.J.2
  • 8
    • 30044435875 scopus 로고    scopus 로고
    • The translation of Helicobacter pylori basic research to patient care
    • quiz 212-213
    • Ernst PB, Peura DA, Crowe SE. The translation of Helicobacter pylori basic research to patient care. Gastroenterology 2006; 130: 188-206; quiz 212-213
    • (2006) Gastroenterology , vol.130 , pp. 188-206
    • Ernst, P.B.1    Peura, D.A.2    Crowe, S.E.3
  • 10
    • 31144461664 scopus 로고    scopus 로고
    • Helicobacter infection and gastric neoplasia
    • Peek RM Jr, Crabtree JE. Helicobacter infection and gastric neoplasia. J Pathol 2006; 208: 233-248
    • (2006) J Pathol , vol.208 , pp. 233-248
    • Peek Jr., R.M.1    Crabtree, J.E.2
  • 12
    • 16244383220 scopus 로고    scopus 로고
    • Genetic polymorphisms of interleukin (IL)-1B, IL-1RN, IL-8, IL-10 and tumor necrosis factor {alpha} and risk of gastric cancer in a Chinese population
    • Lu W, Pan K, Zhang L, Lin D, Miao X, You W. Genetic polymorphisms of interleukin (IL)-1B, IL-1RN, IL-8, IL-10 and tumor necrosis factor {alpha} and risk of gastric cancer in a Chinese population. Carcinogenesis 2005; 26: 631-636
    • (2005) Carcinogenesis , vol.26 , pp. 631-636
    • Lu, W.1    Pan, K.2    Zhang, L.3    Lin, D.4    Miao, X.5    You, W.6
  • 13
    • 20044386655 scopus 로고    scopus 로고
    • The polymorphism interleukin 8 -251 A/T influences the susceptibility of Helicobacter pylori related gastric diseases in the Japanese population
    • Ohyauchi M, Imatani A, Yonechi M, Asano N, Miura A, Iijima K, Koike T, Sekine H, Ohara S, Shimosegawa T. The polymorphism interleukin 8 -251 A/T influences the susceptibility of Helicobacter pylori related gastric diseases in the Japanese population. Gut 2005; 54: 330-335
    • (2005) Gut , vol.54 , pp. 330-335
    • Ohyauchi, M.1    Imatani, A.2    Yonechi, M.3    Asano, N.4    Miura, A.5    Iijima, K.6    Koike, T.7    Sekine, H.8    Ohara, S.9    Shimosegawa, T.10
  • 14
    • 20344389060 scopus 로고    scopus 로고
    • Toll-like receptors: Linking innate and adaptive immunity
    • Pasare C, Medzhitov R. Toll-like receptors: linking innate and adaptive immunity. Adv Exp Med Biol 2005; 560: 11-18
    • (2005) Adv Exp Med Biol , vol.560 , pp. 11-18
    • Pasare, C.1    Medzhitov, R.2
  • 15
    • 12444341944 scopus 로고    scopus 로고
    • Toll-like receptors in innate immunity
    • Takeda K, Akira S. Toll-like receptors in innate immunity. Int Immunol 2005; 17: 1-14
    • (2005) Int Immunol , vol.17 , pp. 1-14
    • Takeda, K.1    Akira, S.2
  • 20
    • 3343010274 scopus 로고    scopus 로고
    • Helicobacter pylori induces apoptosis of human monocytes but not monocyte-derived dendritic cells: Role of the cag pathogenicity island
    • Galgani M, Busiello I, Censini S, Zappacosta S, Racioppi L, Zarrilli R. Helicobacter pylori induces apoptosis of human monocytes but not monocyte-derived dendritic cells: role of the cag pathogenicity island. Infect Immun 2004; 72: 4480-4485
    • (2004) Infect Immun , vol.72 , pp. 4480-4485
    • Galgani, M.1    Busiello, I.2    Censini, S.3    Zappacosta, S.4    Racioppi, L.5    Zarrilli, R.6
  • 24
    • 0026532230 scopus 로고
    • Helicobacter pylori: The African enigma
    • Holcombe C. Helicobacter pylori: the African enigma. Gut 1992; 33: 429-431
    • (1992) Gut , vol.33 , pp. 429-431
    • Holcombe, C.1
  • 26
    • 4544334936 scopus 로고    scopus 로고
    • Oncogenic mechanisms of the Helicobacter pylori CagA protein
    • Hatakeyama M. Oncogenic mechanisms of the Helicobacter pylori CagA protein. Nat Rev Cancer 2004; 4: 688-694
    • (2004) Nat Rev Cancer , vol.4 , pp. 688-694
    • Hatakeyama, M.1
  • 28
    • 21544441173 scopus 로고    scopus 로고
    • NF-kappaB activation and potentiation of proinflammatory responses by the Helicobacter pylori CagA protein
    • Brandt S, Kwok T, Hartig R, König W, Backert S. NF-kappaB activation and potentiation of proinflammatory responses by the Helicobacter pylori CagA protein. Proc Natl Acad Sci USA 2005; 102: 9300-9305
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 9300-9305
    • Brandt, S.1    Kwok, T.2    Hartig, R.3    König, W.4    Backert, S.5
  • 29
    • 33644817536 scopus 로고    scopus 로고
    • Helicobacter pylori CagA transfection of gastric epithelial cells induces interleukin- 8
    • Kim SY, Lee YC, Kim HK, Blaser MJ. Helicobacter pylori CagA transfection of gastric epithelial cells induces interleukin- 8. Cell Microbiol 2006; 8: 97-106
    • (2006) Cell Microbiol , vol.8 , pp. 97-106
    • Kim, S.Y.1    Lee, Y.C.2    Kim, H.K.3    Blaser, M.J.4
  • 30
    • 20544461311 scopus 로고    scopus 로고
    • The role of genome diversity and immune evasion in persistent infection with Helicobacter pylori
    • Cooke CL, Huff JL, Solnick JV. The role of genome diversity and immune evasion in persistent infection with Helicobacter pylori. FEMS Immunol Med Microbiol 2005; 45: 11-23
    • (2005) FEMS Immunol Med Microbiol , vol.45 , pp. 11-23
    • Cooke, C.L.1    Huff, J.L.2    Solnick, J.V.3
  • 31
    • 85047691456 scopus 로고    scopus 로고
    • Helicobacter pylori persistence: Biology and disease
    • Blaser MJ, Atherton JC. Helicobacter pylori persistence: biology and disease. J Clin Invest 2004; 113: 321-333
    • (2004) J Clin Invest , vol.113 , pp. 321-333
    • Blaser, M.J.1    Atherton, J.C.2
  • 32
    • 17044395509 scopus 로고    scopus 로고
    • Intracellular Helicobacter pylori in gastric epithelial progenitors
    • Oh JD, Karam SM, Gordon JI. Intracellular Helicobacter pylori in gastric epithelial progenitors. Proc Natl Acad Sci USA 2005; 102: 5186-5191
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 5186-5191
    • Oh, J.D.1    Karam, S.M.2    Gordon, J.I.3
  • 35
    • 0033618337 scopus 로고    scopus 로고
    • Matrix metalloproteinases
    • Nagase H, Woessner JF Jr. Matrix metalloproteinases. J Biol Chem 1999; 274: 21491-21494
    • (1999) J Biol Chem , vol.274 , pp. 21491-21494
    • Nagase, H.1    Woessner Jr., J.F.2
  • 36
    • 30044433929 scopus 로고    scopus 로고
    • Myofibroblast matrix metalloproteinases activate the neutrophil chemoattractant CXCL7 from intestinal epithelial cells
    • Kruidenier L, MacDonald TT, Collins JE, Pender SL, Sanderson IR. Myofibroblast matrix metalloproteinases activate the neutrophil chemoattractant CXCL7 from intestinal epithelial cells. Gastroenterology 2006; 130: 127-136
    • (2006) Gastroenterology , vol.130 , pp. 127-136
    • Kruidenier, L.1    Macdonald, T.T.2    Collins, J.E.3    Pender, S.L.4    Sanderson, I.R.5
  • 37
    • 0032995903 scopus 로고    scopus 로고
    • Increased expression and cellular localization of inducible nitric oxide synthase and cyclooxygenase 2 in Helicobacter pylori gastritis
    • Fu S, Ramanujam KS, Wong A, Fantry GT, Drachenberg CB, James SP, Meltzer SJ, Wilson KT. Increased expression and cellular localization of inducible nitric oxide synthase and cyclooxygenase 2 in Helicobacter pylori gastritis. Gastroenterology 1999; 116: 1319-1329
    • (1999) Gastroenterology , vol.116 , pp. 1319-1329
    • Fu, S.1    Ramanujam, K.S.2    Wong, A.3    Fantry, G.T.4    Drachenberg, C.B.5    James, S.P.6    Meltzer, S.J.7    Wilson, K.T.8
  • 38
    • 1342347651 scopus 로고    scopus 로고
    • Helicobacter pylori gamma-glutamyltranspeptidase upregulates COX-2 and EGF-related peptide expression in human gastric cells
    • Busiello I, Acquaviva R, Di Popolo A, Blanchard TG, Ricci V, Romano M, Zarrilli R. Helicobacter pylori gamma-glutamyltranspeptidase upregulates COX-2 and EGF-related peptide expression in human gastric cells. Cell Microbiol 2004; 6: 255-267
    • (2004) Cell Microbiol , vol.6 , pp. 255-267
    • Busiello, I.1    Acquaviva, R.2    di Popolo, A.3    Blanchard, T.G.4    Ricci, V.5    Romano, M.6    Zarrilli, R.7
  • 41
    • 0035930508 scopus 로고    scopus 로고
    • Cag+ Helicobacter pylori induce transactivation of the epidermal growth factor receptor in AGS gastric epithelial cells
    • Keates S, Sougioultzis S, Keates AC, Zhao D, Peek RM Jr, Shaw LM, Kelly CP. Cag+ Helicobacter pylori induce transactivation of the epidermal growth factor receptor in AGS gastric epithelial cells. J Biol Chem 2001; 276: 48127-48134
    • (2001) J Biol Chem , vol.276 , pp. 48127-48134
    • Keates, S.1    Sougioultzis, S.2    Keates, A.C.3    Zhao, D.4    Peek Jr., R.M.5    Shaw, L.M.6    Kelly, C.P.7
  • 44
    • 0037838812 scopus 로고    scopus 로고
    • Helicobacter pylori VacA toxin up-regulates vascular endothelial growth factor expression in MKN 28 gastric cells through an epidermal growth factor receptor-, cyclooxygenase-2-dependent mechanism
    • Caputo R, Tuccillo C, Manzo BA, Zarrilli R, Tortora G, Blanco Cdel V, Ricci V, Ciardiello F, Romano M. Helicobacter pylori VacA toxin up-regulates vascular endothelial growth factor expression in MKN 28 gastric cells through an epidermal growth factor receptor-, cyclooxygenase-2-dependent mechanism. Clin Cancer Res 2003; 9: 2015-2021
    • (2003) Clin Cancer Res , vol.9 , pp. 2015-2021
    • Caputo, R.1    Tuccillo, C.2    Manzo, B.A.3    Zarrilli, R.4    Tortora, G.5    Blanco Cdel, V.6    Ricci, V.7    Ciardiello, F.8    Romano, M.9
  • 46
    • 33750429604 scopus 로고    scopus 로고
    • Mechanisms of disease: Helicobacter pylori-related gastric carcinogenesis-implications for chemoprevention
    • Romano M, Ricci V, Zarrilli R. Mechanisms of disease: Helicobacter pylori-related gastric carcinogenesis-implications for chemoprevention. Nat Clin Pract Gastroenterol Hepatol 2006; 3: 622-632
    • (2006) Nat Clin Pract Gastroenterol Hepatol , vol.3 , pp. 622-632
    • Romano, M.1    Ricci, V.2    Zarrilli, R.3
  • 52
    • 0344837816 scopus 로고    scopus 로고
    • Beta-catenin expression in intramucosal neoplastic lesions of the stomach. Comparative analysis of adenoma/dysplasia, adenocarcinoma and signet-ring cell carcinoma
    • Tsukashita S, Kushima R, Bamba M, Nakamura E, Mukaisho K, Sugihara H, Hattori T. Beta-catenin expression in intramucosal neoplastic lesions of the stomach. Comparative analysis of adenoma/dysplasia, adenocarcinoma and signet-ring cell carcinoma. Oncology 2003; 64: 251-258
    • (2003) Oncology , vol.64 , pp. 251-258
    • Tsukashita, S.1    Kushima, R.2    Bamba, M.3    Nakamura, E.4    Mukaisho, K.5    Sugihara, H.6    Hattori, T.7
  • 54
    • 77952903266 scopus 로고    scopus 로고
    • Helicobacter pylori: Gastric cancer and beyond
    • Polk DB, Peek RM Jr. Helicobacter pylori: gastric cancer and beyond. Nat Rev Cancer 2010; 10: 403-414
    • (2010) Nat Rev Cancer , vol.10 , pp. 403-414
    • Polk, D.B.1    Peek Jr., R.M.2
  • 56
    • 0036192345 scopus 로고    scopus 로고
    • Voyage of Helicobacter pylori in human stomach: Odyssey of a bacterium
    • Ricci V, Zarrilli R, Romano M. Voyage of Helicobacter pylori in human stomach: odyssey of a bacterium. Dig Liver Dis 2002; 34: 2-8
    • (2002) Dig Liver Dis , vol.34 , pp. 2-8
    • Ricci, V.1    Zarrilli, R.2    Romano, M.3
  • 57
    • 33947314338 scopus 로고    scopus 로고
    • Intracellular, intercellular, and stromal invasion of gastric mucosa, preneoplastic lesions, and cancer by Helicobacter pylori
    • Necchi V, Candusso ME, Tava F, Luinetti O, Ventura U, Fiocca R, Ricci V, Solcia E. Intracellular, intercellular, and stromal invasion of gastric mucosa, preneoplastic lesions, and cancer by Helicobacter pylori. Gastroenterology 2007; 132: 1009-1023
    • (2007) Gastroenterology , vol.132 , pp. 1009-1023
    • Necchi, V.1    Candusso, M.E.2    Tava, F.3    Luinetti, O.4    Ventura, U.5    Fiocca, R.6    Ricci, V.7    Solcia, E.8
  • 58
    • 0038061773 scopus 로고    scopus 로고
    • Helicobacter pylori: An invading microorganism? A review
    • Petersen AM, Krogfelt KA. Helicobacter pylori: an invading microorganism? A review. FEMS Immunol Med Microbiol 2003; 36: 117-126
    • (2003) FEMS Immunol Med Microbiol , vol.36 , pp. 117-126
    • Petersen, A.M.1    Krogfelt, K.A.2
  • 59
    • 34047250343 scopus 로고    scopus 로고
    • Helicobacter pylori is invasive and it may be a facultative intracellular organism
    • Dubois A, Borén T. Helicobacter pylori is invasive and it may be a facultative intracellular organism. Cell Microbiol 2007; 9: 1108-1116
    • (2007) Cell Microbiol , vol.9 , pp. 1108-1116
    • Dubois, A.1    Borén, T.2
  • 60
    • 27644545359 scopus 로고    scopus 로고
    • Helicobacter pylori virulence factors: Facts and fantasies
    • Lu H, Yamaoka Y, Graham DY. Helicobacter pylori virulence factors: facts and fantasies. Curr Opin Gastroenterol 2005; 21: 653-659
    • (2005) Curr Opin Gastroenterol , vol.21 , pp. 653-659
    • Lu, H.1    Yamaoka, Y.2    Graham, D.Y.3
  • 61
    • 0346962995 scopus 로고    scopus 로고
    • Immunosuppressive and proinflammatory activities of the VacA toxin of Helicobacter pylori
    • Montecucco C, de Bernard M. Immunosuppressive and proinflammatory activities of the VacA toxin of Helicobacter pylori. J Exp Med 2003; 198: 1767-1771
    • (2003) J Exp Med , vol.198 , pp. 1767-1771
    • Montecucco, C.1    de Bernard, M.2
  • 62
    • 34447092208 scopus 로고    scopus 로고
    • Immunology of Helicobacter pylori: Insights into the failure of the immune response and perspectives on vaccine studies
    • Wilson KT, Crabtree JE. Immunology of Helicobacter pylori: insights into the failure of the immune response and perspectives on vaccine studies. Gastroenterology 2007; 133: 288-308
    • (2007) Gastroenterology , vol.133 , pp. 288-308
    • Wilson, K.T.1    Crabtree, J.E.2
  • 63
    • 0345269172 scopus 로고    scopus 로고
    • Intracellular and interstitial expression of Helicobacter pylori virulence genes in gastric precancerous intestinal metaplasia and adenocarcinoma
    • Semino-Mora C, Doi SQ, Marty A, Simko V, Carlstedt I, Dubois A. Intracellular and interstitial expression of Helicobacter pylori virulence genes in gastric precancerous intestinal metaplasia and adenocarcinoma. J Infect Dis 2003; 187: 1165-1177
    • (2003) J Infect Dis , vol.187 , pp. 1165-1177
    • Semino-Mora, C.1    Doi, S.Q.2    Marty, A.3    Simko, V.4    Carlstedt, I.5    Dubois, A.6
  • 64
  • 65
    • 0031909892 scopus 로고    scopus 로고
    • Assessment of invasion frequencies of cultured HEp-2 cells by clinical isolates of Helicobacter pylori using an acridine orange assay
    • Wilkinson SM, Uhl JR, Kline BC, Cockerill FR 3rd. Assessment of invasion frequencies of cultured HEp-2 cells by clinical isolates of Helicobacter pylori using an acridine orange assay. J Clin Pathol 1998; 51: 127-133
    • (1998) J Clin Pathol , vol.51 , pp. 127-133
    • Wilkinson, S.M.1    Uhl, J.R.2    Kline, B.C.3    Cockerill, F.R.4
  • 66
    • 0033456273 scopus 로고    scopus 로고
    • Altered states: Involvement of phosphorylated CagA in the induction of host cellular growth changes by Helicobacter pylori
    • Segal ED, Cha J, Lo J, Falkow S, Tompkins LS. Altered states: involvement of phosphorylated CagA in the induction of host cellular growth changes by Helicobacter pylori. Proc Natl Acad Sci USA 1999; 96: 14559-14564
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 14559-14564
    • Segal, E.D.1    Cha, J.2    Lo, J.3    Falkow, S.4    Tompkins, L.S.5
  • 67
    • 0034235373 scopus 로고    scopus 로고
    • Pylori activates NF-kappaB through a signaling pathway involving IkappaB kinases, NF-kappaB-inducing kinase, TRAF2, and TRAF6 in gastric cancer cells
    • Maeda S, Yoshida H, Ogura K, Mitsuno Y, Hirata Y, Yamaji Y, Akanuma M, Shiratori Y, Omata M. H. pylori activates NF-kappaB through a signaling pathway involving IkappaB kinases, NF-kappaB-inducing kinase, TRAF2, and TRAF6 in gastric cancer cells. Gastroenterology 2000; 119: 97-108
    • (2000) Gastroenterology , vol.119 , pp. 97-108
    • Maeda, S.1    Yoshida, H.2    Ogura, K.3    Mitsuno, Y.4    Hirata, Y.5    Yamaji, Y.6    Akanuma, M.7    Shiratori, Y.8    Omata, M.H.9
  • 69
    • 78249235456 scopus 로고    scopus 로고
    • In vivo accumulation of Helicobacter pylori products, NOD1, ubiquitinated proteins and proteasome in a novel cytoplasmic structure
    • Necchi V, Sommi P, Ricci V, Solcia E. In vivo accumulation of Helicobacter pylori products, NOD1, ubiquitinated proteins and proteasome in a novel cytoplasmic structure. PLoS One 2010; 5: e9716
    • (2010) PLoS One , vol.5
    • Necchi, V.1    Sommi, P.2    Ricci, V.3    Solcia, E.4
  • 70
    • 23044506681 scopus 로고    scopus 로고
    • The ubiquitin-proteasome pathway and its role in cancer
    • Mani A, Gelmann EP. The ubiquitin-proteasome pathway and its role in cancer. J Clin Oncol 2005; 23: 4776-4789
    • (2005) J Clin Oncol , vol.23 , pp. 4776-4789
    • Mani, A.1    Gelmann, E.P.2
  • 71
    • 0842265548 scopus 로고    scopus 로고
    • Toll-like receptor 2 (TLR2) and TLR4 are present inside human dendritic cells, associated with microtubules and the Golgi apparatus but are not detectable on the cell surface: Integrity of microtubules is required for interleukin- 12 production in response to internalized bacteria
    • Uronen-Hansson H, Allen J, Osman M, Squires G, Klein N, Callard RE. Toll-like receptor 2 (TLR2) and TLR4 are present inside human dendritic cells, associated with microtubules and the Golgi apparatus but are not detectable on the cell surface: integrity of microtubules is required for interleukin- 12 production in response to internalized bacteria. Immunology 2004; 111: 173-178
    • (2004) Immunology , vol.111 , pp. 173-178
    • Uronen-Hansson, H.1    Allen, J.2    Osman, M.3    Squires, G.4    Klein, N.5    Callard, R.E.6
  • 72
    • 27144526644 scopus 로고    scopus 로고
    • Monocyte-derived dendritic cells activated by bacteria or by bacteria-stimulated epithelial cells are functionally different
    • Rimoldi M, Chieppa M, Larghi P, Vulcano M, Allavena P, Rescigno M. Monocyte-derived dendritic cells activated by bacteria or by bacteria-stimulated epithelial cells are functionally different. Blood 2005; 106: 2818-2826
    • (2005) Blood , vol.106 , pp. 2818-2826
    • Rimoldi, M.1    Chieppa, M.2    Larghi, P.3    Vulcano, M.4    Allavena, P.5    Rescigno, M.6
  • 73
    • 65649104720 scopus 로고    scopus 로고
    • Evidence for transepithelial dendritic cells in human H. pylori active gastritis
    • Necchi V, Manca R, Ricci V, Solcia E. Evidence for transepithelial dendritic cells in human H. pylori active gastritis. Helicobacter 2009; 14: 208-222
    • (2009) Helicobacter , vol.14 , pp. 208-222
    • Necchi, V.1    Manca, R.2    Ricci, V.3    Solcia, E.4
  • 74
    • 0035854530 scopus 로고    scopus 로고
    • Sensing pathogens and tuning immune responses
    • Pulendran B, Palucka K, Banchereau J. Sensing pathogens and tuning immune responses. Science 2001; 293: 253-256
    • (2001) Science , vol.293 , pp. 253-256
    • Pulendran, B.1    Palucka, K.2    Banchereau, J.3
  • 75
    • 33947144681 scopus 로고    scopus 로고
    • Phagocytosis and persistence of Helicobacter pylori
    • Allen LA. Phagocytosis and persistence of Helicobacter pylori. Cell Microbiol 2007; 9: 817-828
    • (2007) Cell Microbiol , vol.9 , pp. 817-828
    • Allen, L.A.1
  • 77
    • 15944418287 scopus 로고    scopus 로고
    • Helicobacter pylori VacA, a paradigm for toxin multifunctionality
    • Cover TL, Blanke SR. Helicobacter pylori VacA, a paradigm for toxin multifunctionality. Nat Rev Microbiol 2005; 3: 320-332
    • (2005) Nat Rev Microbiol , vol.3 , pp. 320-332
    • Cover, T.L.1    Blanke, S.R.2
  • 78
    • 40849085080 scopus 로고    scopus 로고
    • SagA of CagA in Helicobacter pylori pathogenesis
    • Hatakeyama M. SagA of CagA in Helicobacter pylori pathogenesis. Curr Opin Microbiol 2008; 11: 30-37
    • (2008) Curr Opin Microbiol , vol.11 , pp. 30-37
    • Hatakeyama, M.1
  • 79
    • 77952133535 scopus 로고    scopus 로고
    • The versatility of Helicobacter pylori CagA effector protein functions: The master key hypothesis
    • Backert S, Tegtmeyer N, Selbach M. The versatility of Helicobacter pylori CagA effector protein functions: The master key hypothesis. Helicobacter 2010; 15: 163-176
    • (2010) Helicobacter , vol.15 , pp. 163-176
    • Backert, S.1    Tegtmeyer, N.2    Selbach, M.3
  • 80
    • 74949095434 scopus 로고    scopus 로고
    • Pleiotropic actions of Helicobacter pylori vacuolating cytotoxin, VacA
    • Isomoto H, Moss J, Hirayama T. Pleiotropic actions of Helicobacter pylori vacuolating cytotoxin, VacA. Tohoku J Exp Med 2010; 220: 3-14
    • (2010) Tohoku J Exp Med , vol.220 , pp. 3-14
    • Isomoto, H.1    Moss, J.2    Hirayama, T.3
  • 81
    • 0042825898 scopus 로고    scopus 로고
    • Gastric cell apoptosis and H. pylori: Has the main function of VacA finally been identified?
    • Boquet P, Ricci V, Galmiche A, Gauthier NC. Gastric cell apoptosis and H. pylori: has the main function of VacA finally been identified? Trends Microbiol 2003; 11: 410-413
    • (2003) Trends Microbiol , vol.11 , pp. 410-413
    • Boquet, P.1    Ricci, V.2    Galmiche, A.3    Gauthier, N.C.4
  • 83
    • 0030865151 scopus 로고    scopus 로고
    • Channel-forming toxins: Tales of transformation
    • Gouaux E. Channel-forming toxins: tales of transformation. Curr Opin Struct Biol 1997; 7: 566-573
    • (1997) Curr Opin Struct Biol , vol.7 , pp. 566-573
    • Gouaux, E.1
  • 84
    • 46449135449 scopus 로고    scopus 로고
    • Helicobacter pylori VacA subdomain required for intracellular toxin activity and assembly of functional oligomeric complexes
    • Ivie SE, McClain MS, Torres VJ, Algood HM, Lacy DB, Yang R, Blanke SR, Cover TL. Helicobacter pylori VacA subdomain required for intracellular toxin activity and assembly of functional oligomeric complexes. Infect Immun 2008; 76: 2843-2851
    • (2008) Infect Immun , vol.76 , pp. 2843-2851
    • Ivie, S.E.1    McClain, M.S.2    Torres, V.J.3    Algood, H.M.4    Lacy, D.B.5    Yang, R.6    Blanke, S.R.7    Cover, T.L.8
  • 89
    • 0037373880 scopus 로고    scopus 로고
    • Induction of gastric epithelial cell apoptosis by Helicobacter pylori vacuolating cytotoxin
    • Cover TL, Krishna US, Israel DA, Peek RM Jr. Induction of gastric epithelial cell apoptosis by Helicobacter pylori vacuolating cytotoxin. Cancer Res 2003; 63: 951-957
    • (2003) Cancer Res , vol.63 , pp. 951-957
    • Cover, T.L.1    Krishna, U.S.2    Israel, D.A.3    Peek Jr., R.M.4
  • 90
    • 70350230158 scopus 로고    scopus 로고
    • Relationship between Vac A toxin and ammonia in Helicobacter pylori-induced apoptosis in human gastric epithelial cells
    • Chiozzi V, Mazzini G, Oldani A, Sciullo A, Ventura U, Romano M, Boquet P, Ricci V. Relationship between Vac A toxin and ammonia in Helicobacter pylori-induced apoptosis in human gastric epithelial cells. J Physiol Pharmacol 2009; 60: 23-30
    • (2009) J Physiol Pharmacol , vol.60 , pp. 23-30
    • Chiozzi, V.1    Mazzini, G.2    Oldani, A.3    Sciullo, A.4    Ventura, U.5    Romano, M.6    Boquet, P.7    Ricci, V.8
  • 95
    • 0033748047 scopus 로고    scopus 로고
    • High cell sensitivity to Helicobacter pylori VacA toxin depends on a GPI-anchored protein and is not blocked by inhibition of the clathrin-mediated pathway of endocytosis
    • Ricci V, Galmiche A, Doye A, Necchi V, Solcia E, Boquet P. High cell sensitivity to Helicobacter pylori VacA toxin depends on a GPI-anchored protein and is not blocked by inhibition of the clathrin-mediated pathway of endocytosis. Mol Biol Cell 2000; 11: 3897-3909
    • (2000) Mol Biol Cell , vol.11 , pp. 3897-3909
    • Ricci, V.1    Galmiche, A.2    Doye, A.3    Necchi, V.4    Solcia, E.5    Boquet, P.6
  • 96
    • 0036232040 scopus 로고    scopus 로고
    • GPI-anchored proteins are delivered to recycling endosomes via a distinct cdc42-regulated, clathrin-independent pinocytic pathway
    • Sabharanjak S, Sharma P, Parton RG, Mayor S. GPI-anchored proteins are delivered to recycling endosomes via a distinct cdc42-regulated, clathrin-independent pinocytic pathway. Dev Cell 2002; 2: 411-423
    • (2002) Dev Cell , vol.2 , pp. 411-423
    • Sabharanjak, S.1    Sharma, P.2    Parton, R.G.3    Mayor, S.4
  • 97
    • 34547114456 scopus 로고    scopus 로고
    • Pathways of clathrin-independent endocytosis
    • Mayor S, Pagano RE. Pathways of clathrin-independent endocytosis. Nat Rev Mol Cell Biol 2007; 8: 603-612
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 603-612
    • Mayor, S.1    Pagano, R.E.2
  • 98
    • 77955057786 scopus 로고    scopus 로고
    • Molecules, mechanisms, and cellular roles of clathrin-independent endocytosis
    • Howes MT, Mayor S, Parton RG. Molecules, mechanisms, and cellular roles of clathrin-independent endocytosis. Curr Opin Cell Biol 2010; 22: 519-527
    • (2010) Curr Opin Cell Biol , vol.22 , pp. 519-527
    • Howes, M.T.1    Mayor, S.2    Parton, R.G.3
  • 99
    • 26244459823 scopus 로고    scopus 로고
    • Helicobacter pylori VacA cytotoxin: A probe for a clathrin-independent and Cdc42-dependent pinocytic pathway routed to late endosomes
    • Gauthier NC, Monzo P, Kaddai V, Doye A, Ricci V, Boquet P. Helicobacter pylori VacA cytotoxin: a probe for a clathrin-independent and Cdc42-dependent pinocytic pathway routed to late endosomes. Mol Biol Cell 2005; 16: 4852-4866
    • (2005) Mol Biol Cell , vol.16 , pp. 4852-4866
    • Gauthier, N.C.1    Monzo, P.2    Kaddai, V.3    Doye, A.4    Ricci, V.5    Boquet, P.6
  • 100
    • 33745520896 scopus 로고    scopus 로고
    • Helicobacter pylori VacA toxin: A tool to study novel early endosomes
    • Gauthier NC, Ricci V, Landraud L, Boquet P. Helicobacter pylori VacA toxin: a tool to study novel early endosomes. Trends Microbiol 2006; 14: 292-294
    • (2006) Trends Microbiol , vol.14 , pp. 292-294
    • Gauthier, N.C.1    Ricci, V.2    Landraud, L.3    Boquet, P.4
  • 101
  • 102
    • 78249272018 scopus 로고    scopus 로고
    • Sphingomyelin is important for the cellular entry and intracellular localization of Helicobacter pylori VacA
    • Gupta VR, Wilson BA, Blanke SR. Sphingomyelin is important for the cellular entry and intracellular localization of Helicobacter pylori VacA. Cell Microbiol 2010; 12: 1517-1533
    • (2010) Cell Microbiol , vol.12 , pp. 1517-1533
    • Gupta, V.R.1    Wilson, B.A.2    Blanke, S.R.3
  • 104
    • 0042932364 scopus 로고    scopus 로고
    • Helicobacter pylori vacuolating cytotoxin inhibits T lymphocyte activation
    • Gebert B, Fischer W, Weiss E, Hoffmann R, Haas R. Helicobacter pylori vacuolating cytotoxin inhibits T lymphocyte activation. Science 2003; 301: 1099-1102
    • (2003) Science , vol.301 , pp. 1099-1102
    • Gebert, B.1    Fischer, W.2    Weiss, E.3    Hoffmann, R.4    Haas, R.5
  • 106
    • 2442682964 scopus 로고    scopus 로고
    • Inhibition of primary human T cell proliferation by Helicobacter pylori vacuolating toxin (VacA) is independent of VacA effects on IL-2 secretion
    • Sundrud MS, Torres VJ, Unutmaz D, Cover TL. Inhibition of primary human T cell proliferation by Helicobacter pylori vacuolating toxin (VacA) is independent of VacA effects on IL-2 secretion. Proc Natl Acad Sci USA 2004; 101: 7727-7732
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 7727-7732
    • Sundrud, M.S.1    Torres, V.J.2    Unutmaz, D.3    Cover, T.L.4
  • 108
    • 33751258622 scopus 로고    scopus 로고
    • Helicobacter pylori VacA toxin inhibits human immunodeficiency virus infection of primary human T cells
    • Oswald-Richter K, Torres VJ, Sundrud MS, VanCompernolle SE, Cover TL, Unutmaz D. Helicobacter pylori VacA toxin inhibits human immunodeficiency virus infection of primary human T cells. J Virol 2006; 80: 11767-11775
    • (2006) J Virol , vol.80 , pp. 11767-11775
    • Oswald-Richter, K.1    Torres, V.J.2    Sundrud, M.S.3    Vancompernolle, S.E.4    Cover, T.L.5    Unutmaz, D.6
  • 109
    • 38049076855 scopus 로고    scopus 로고
    • Helicobacter pylori vacuolating cytotoxin inhibits activation-induced proliferation of human T and B lymphocyte subsets
    • Torres VJ, VanCompernolle SE, Sundrud MS, Unutmaz D, Cover TL. Helicobacter pylori vacuolating cytotoxin inhibits activation-induced proliferation of human T and B lymphocyte subsets. J Immunol 2007; 179: 5433-5440
    • (2007) J Immunol , vol.179 , pp. 5433-5440
    • Torres, V.J.1    Vancompernolle, S.E.2    Sundrud, M.S.3    Unutmaz, D.4    Cover, T.L.5
  • 113
    • 1642464598 scopus 로고    scopus 로고
    • Clustering and redistribution of late endocytic compartments in response to Helicobacter pylori vacuolating toxin
    • Li Y, Wandinger-Ness A, Goldenring JR, Cover TL. Clustering and redistribution of late endocytic compartments in response to Helicobacter pylori vacuolating toxin. Mol Biol Cell 2004; 15: 1946-1959
    • (2004) Mol Biol Cell , vol.15 , pp. 1946-1959
    • Li, Y.1    Wandinger-Ness, A.2    Goldenring, J.R.3    Cover, T.L.4
  • 115
    • 71549146571 scopus 로고    scopus 로고
    • The Arp2/3 activator WASH controls the fission of endosomes through a large multiprotein complex
    • Derivery E, Sousa C, Gautier JJ, Lombard B, Loew D, Gautreau A. The Arp2/3 activator WASH controls the fission of endosomes through a large multiprotein complex. Dev Cell 2009; 17: 712-723
    • (2009) Dev Cell , vol.17 , pp. 712-723
    • Derivery, E.1    Sousa, C.2    Gautier, J.J.3    Lombard, B.4    Loew, D.5    Gautreau, A.6
  • 116
    • 33744960020 scopus 로고    scopus 로고
    • Helicobacter pylori vacuolating cytotoxin induces activation of the proapoptotic proteins Bax and Bak, leading to cytochrome c release and cell death, independent of vacuolation
    • Yamasaki E, Wada A, Kumatori A, Nakagawa I, Funao J, Nakayama M, Hisatsune J, Kimura M, Moss J, Hirayama T. Helicobacter pylori vacuolating cytotoxin induces activation of the proapoptotic proteins Bax and Bak, leading to cytochrome c release and cell death, independent of vacuolation. J Biol Chem 2006; 281: 11250-11259
    • (2006) J Biol Chem , vol.281 , pp. 11250-11259
    • Yamasaki, E.1    Wada, A.2    Kumatori, A.3    Nakagawa, I.4    Funao, J.5    Nakayama, M.6    Hisatsune, J.7    Kimura, M.8    Moss, J.9    Hirayama, T.10
  • 118
    • 33645865541 scopus 로고    scopus 로고
    • Type IV secretion systems and their effectors in bacterial pathogenesis
    • Backert S, Meyer TF. Type IV secretion systems and their effectors in bacterial pathogenesis. Curr Opin Microbiol 2006; 9: 207-217
    • (2006) Curr Opin Microbiol , vol.9 , pp. 207-217
    • Backert, S.1    Meyer, T.F.2
  • 121
    • 77955292149 scopus 로고    scopus 로고
    • Helicobacter pylori exploits host membrane phosphatidylserine for delivery, localization, and pathophysiological action of the CagA oncoprotein
    • Murata-Kamiya N, Kikuchi K, Hayashi T, Higashi H, Hatakeyama M. Helicobacter pylori exploits host membrane phosphatidylserine for delivery, localization, and pathophysiological action of the CagA oncoprotein. Cell Host Microbe 2010; 7: 399-411
    • (2010) Cell Host Microbe , vol.7 , pp. 399-411
    • Murata-Kamiya, N.1    Kikuchi, K.2    Hayashi, T.3    Higashi, H.4    Hatakeyama, M.5
  • 122
    • 0035320135 scopus 로고    scopus 로고
    • Identification of a tyrosine-phosphorylated 35 kDa carboxy-terminal fragment (p35CagA) of the Helicobacter pylori CagA protein in phagocytic cells: Processing or breakage?
    • Moese S, Selbach M, Zimny-Arndt U, Jungblut PR, Meyer TF, Backert S. Identification of a tyrosine-phosphorylated 35 kDa carboxy-terminal fragment (p35CagA) of the Helicobacter pylori CagA protein in phagocytic cells: processing or breakage? Proteomics 2001; 1: 618-629
    • (2001) Proteomics , vol.1 , pp. 618-629
    • Moese, S.1    Selbach, M.2    Zimny-Arndt, U.3    Jungblut, P.R.4    Meyer, T.F.5    Backert, S.6
  • 123
    • 0035143451 scopus 로고    scopus 로고
    • Interaction of Helicobacter pylori with professional phagocytes: Role of the cag pathogenicity island and translocation, phosphorylation and processing of CagA
    • Odenbreit S, Gebert B, Püls J, Fischer W, Haas R. Interaction of Helicobacter pylori with professional phagocytes: role of the cag pathogenicity island and translocation, phosphorylation and processing of CagA. Cell Microbiol 2001; 3: 21-31
    • (2001) Cell Microbiol , vol.3 , pp. 21-31
    • Odenbreit, S.1    Gebert, B.2    Püls, J.3    Fischer, W.4    Haas, R.5
  • 124
    • 0037415684 scopus 로고    scopus 로고
    • The Helicobacter pylori CagA protein induces cortactin dephosphorylation and actin rearrangement by c-Src inactivation
    • Selbach M, Moese S, Hurwitz R, Hauck CR, Meyer TF, Backert S. The Helicobacter pylori CagA protein induces cortactin dephosphorylation and actin rearrangement by c-Src inactivation. EMBO J 2003; 22: 515-528
    • (2003) EMBO J , vol.22 , pp. 515-528
    • Selbach, M.1    Moese, S.2    Hurwitz, R.3    Hauck, C.R.4    Meyer, T.F.5    Backert, S.6
  • 128
    • 59849112591 scopus 로고    scopus 로고
    • Importance of EGF receptor, HER2/Neu and Erk1/2 kinase signalling for host cell elongation and scattering induced by the Helicobacter pylori CagA protein: Antagonistic effects of the vacuolating cytotoxin VacA
    • Tegtmeyer N, Zabler D, Schmidt D, Hartig R, Brandt S, Backert S. Importance of EGF receptor, HER2/Neu and Erk1/2 kinase signalling for host cell elongation and scattering induced by the Helicobacter pylori CagA protein: antagonistic effects of the vacuolating cytotoxin VacA. Cell Microbiol 2009; 11: 488-505
    • (2009) Cell Microbiol , vol.11 , pp. 488-505
    • Tegtmeyer, N.1    Zabler, D.2    Schmidt, D.3    Hartig, R.4    Brandt, S.5    Backert, S.6
  • 129
    • 0032903930 scopus 로고    scopus 로고
    • Cellular microbiology: Can we learn cell physiology from microorganisms?
    • Fasano A. Cellular microbiology: can we learn cell physiology from microorganisms? Am J Physiol 1999; 276: C765-C776
    • (1999) Am J Physiol , vol.276
    • Fasano, A.1
  • 130
    • 70349211747 scopus 로고    scopus 로고
    • Coadaptation of Helicobacter pylori and humans: Ancient history, modern implications
    • Atherton JC, Blaser MJ. Coadaptation of Helicobacter pylori and humans: ancient history, modern implications. J Clin Invest 2009; 119: 2475-2487
    • (2009) J Clin Invest , vol.119 , pp. 2475-2487
    • Atherton, J.C.1    Blaser, M.J.2


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