The Helicobacter pylori CagA protein induces cortactin dephosphorylation and actin rearrangement by c-Src inactivation

EMBO Journal

Volumn 22, Issue 3, 2003, Pages 515-528

  Selbach, Matthias ^a   Moese, Stefan ^a   Hurwitz, Robert ^a   Hauck, Christof R ^b   Meyer, Thomas F ^a   Backert, Steffen ^a  

^a MAX PLANCK INSTITUTE FOR INFECTION BIOLOGY   (Germany)

^b UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

Actin cytoskeleton; Molecular pathogenesis; Type IV secretion; Tyrosine phosphorylation

Indexed keywords

ACTIN; CAGA PROTEIN; CORTACTIN; PROTEIN TYROSINE KINASE; VIRULENCE FACTOR;

ACTIN FILAMENT; ANIMAL CELL; ARTICLE; BACTERIAL VIRULENCE; CONTROLLED STUDY; ENZYME INHIBITION; EPITHELIUM CELL; HELICOBACTER PYLORI; HUMAN; HUMAN CELL; NEGATIVE FEEDBACK; NONHUMAN; ONCOGENE SRC; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN PHOSPHORYLATION; PROTEIN TRANSPORT;

ACTINS; ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; CELLS, CULTURED; CORTACTIN; CYTOSKELETON; FEEDBACK, BIOCHEMICAL; GASTRIC MUCOSA; HELICOBACTER PYLORI; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICROFILAMENT PROTEINS; MICROSCOPY, CONFOCAL; MODELS, BIOLOGICAL; PHOSPHORYLATION; PROTEIN-TYROSINE KINASES; PROTEIN-TYROSINE-PHOSPHATASE; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION; TYROSINE; VIRULENCE FACTORS;

ANIMALIA; BACTERIA (MICROORGANISMS); EUKARYOTA; HELICOBACTER; HELICOBACTER PYLORI;

EID: 0037415684     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/cdg050     Document Type: Article

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