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Volumn 63, Issue 5, 2003, Pages 951-957

Induction of gastric epithelial cell apoptosis by Helicobacter pylori vacuolating cytotoxin

Author keywords

[No Author keywords available]

Indexed keywords

CYTOTOXIN; UNCLASSIFIED DRUG; VACUOLATING TOXIN;

EID: 0037373880     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (262)

References (76)
  • 1
    • 0029956022 scopus 로고    scopus 로고
    • Helicobacter pylori and gastric cancer: State of the art
    • Correa, P. Helicobacter pylori and gastric cancer: state of the art. Cancer Epidemiol. Biomark. Prev., 5: 477-481, 1996.
    • (1996) Cancer Epidemiol. Biomark. Prev. , vol.5 , pp. 477-481
    • Correa, P.1
  • 2
    • 0025871037 scopus 로고
    • Association between infection with Helicobacter pylori and risk of gastric cancer: Evidence from a prospective investigation
    • Forman, D., Newell, D. G., Fullerton, F., Yarnell, J. W., Stacey, A. R., Wald, N., and Sitas, F. Association between infection with Helicobacter pylori and risk of gastric cancer: evidence from a prospective investigation. BMJ, 302: 1302-1305, 1991.
    • (1991) BMJ , vol.302 , pp. 1302-1305
    • Forman, D.1    Newell, D.G.2    Fullerton, F.3    Yarnell, J.W.4    Stacey, A.R.5    Wald, N.6    Sitas, F.7
  • 6
    • 0036370334 scopus 로고    scopus 로고
    • Helicobacter pylori and gastrointestinal tract adenocarcinomas
    • Peek, R. M., Jr., and Blaser, M. J. Helicobacter pylori and gastrointestinal tract adenocarcinomas. Nat. Rev. Cancer, 2: 28-37, 2002.
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 28-37
    • Peek R.M., Jr.1    Blaser, M.J.2
  • 7
    • 0031714446 scopus 로고    scopus 로고
    • Helicobacter pylori infection induces gastric cancer in Mongolian gerbils
    • Watanabe, T., Tada, M., Nagai, H., Sasaki, S., and Nakao, M. Helicobacter pylori infection induces gastric cancer in Mongolian gerbils. Gastroenterology, 115: 642-648, 1998.
    • (1998) Gastroenterology , vol.115 , pp. 642-648
    • Watanabe, T.1    Tada, M.2    Nagai, H.3    Sasaki, S.4    Nakao, M.5
  • 8
    • 0032189467 scopus 로고    scopus 로고
    • Development of Helicobacter pylori-induced gastric carcinoma in Mongolian gerbils
    • Honda, S., Fujioka, T., Tokieda, M., Satoh, R., Nishizono, A., and Nasu, M. Development of Helicobacter pylori-induced gastric carcinoma in Mongolian gerbils. Cancer Res., 58: 4255-4259, 1998.
    • (1998) Cancer Res. , vol.58 , pp. 4255-4259
    • Honda, S.1    Fujioka, T.2    Tokieda, M.3    Satoh, R.4    Nishizono, A.5    Nasu, M.6
  • 9
    • 0026739795 scopus 로고
    • Purification and characterization of the vacuolating toxin from Helicobacter pylori
    • Cover, T. L., and Blaser, M. J. Purification and characterization of the vacuolating toxin from Helicobacter pylori. J. Biol. Chem., 267: 10570-10575, 1992.
    • (1992) J. Biol. Chem. , vol.267 , pp. 10570-10575
    • Cover, T.L.1    Blaser, M.J.2
  • 10
    • 0028308711 scopus 로고
    • Divergence of genetic sequences for the vacuolating cytotoxin among Helicobacter pylori strains
    • Cover, T. L., Tummuru, M. K., Cao, P., Thompson, S. A., and Blaser, M. J. Divergence of genetic sequences for the vacuolating cytotoxin among Helicobacter pylori strains. J. Biol. Chem., 269: 10566-10573, 1994.
    • (1994) J. Biol. Chem. , vol.269 , pp. 10566-10573
    • Cover, T.L.1    Tummuru, M.K.2    Cao, P.3    Thompson, S.A.4    Blaser, M.J.5
  • 12
    • 0028365481 scopus 로고
    • Genetic analysis of the Helicobacter pylori vacuolating cytotoxin: Structural similarities with the IgA protease type of exported protein
    • Schmitt, W., and Haas, R. Genetic analysis of the Helicobacter pylori vacuolating cytotoxin: structural similarities with the IgA protease type of exported protein. Mol. Microbiol., 12: 307-319, 1994.
    • (1994) Mol. Microbiol. , vol.12 , pp. 307-319
    • Schmitt, W.1    Haas, R.2
  • 13
    • 0028280638 scopus 로고
    • Pathological significance and molecular characterization of the vacuolating toxin gene of Helicobacter pylori
    • Phadnis, S. H., Ilver, D., Janzon, L., Normark, S., and Westblom, T. U. Pathological significance and molecular characterization of the vacuolating toxin gene of Helicobacter pylori. Infect. Immun., 62: 1557-1565, 1994.
    • (1994) Infect. Immun. , vol.62 , pp. 1557-1565
    • Phadnis, S.H.1    Ilver, D.2    Janzon, L.3    Normark, S.4    Westblom, T.U.5
  • 14
    • 0001605046 scopus 로고    scopus 로고
    • Vacuolating cytotoxin
    • H. L. T. Mobley, G. L. Mendz, and S. L. Hazell (eds.). Washington DC: ASM Press
    • Atherton, J. C., Cover, T. L., Papini, E., and Telford, J. L. Vacuolating cytotoxin. In: H. L. T. Mobley, G. L. Mendz, and S. L. Hazell (eds.), Helicobacter pylori: Physiology and Genetics, pp. 97-110. Washington DC: ASM Press, 2001.
    • (2001) Helicobacter Pylori: Physiology and Genetics , pp. 97-110
    • Atherton, J.C.1    Cover, T.L.2    Papini, E.3    Telford, J.L.4
  • 16
    • 0026713040 scopus 로고
    • Potentiation of Helicobacter pylori vacuolating toxin activity by nicotine and other weak bases
    • Cover, T. L., Vaughn, S. G., Cao, P., and Blaser, M. J. Potentiation of Helicobacter pylori vacuolating toxin activity by nicotine and other weak bases. J. Infect. Dis., 166: 1073-1078, 1992.
    • (1992) J. Infect. Dis. , vol.166 , pp. 1073-1078
    • Cover, T.L.1    Vaughn, S.G.2    Cao, P.3    Blaser, M.J.4
  • 18
    • 0030868990 scopus 로고    scopus 로고
    • Vacuoles induced by Helicobacter pylori toxin contain both late endosomal and lysosomal markers
    • Molinari, M., Galli, C., Norais, N., Telford, J. L., Rappuoli, R., Luzio, J. P., and Montecucco, C. Vacuoles induced by Helicobacter pylori toxin contain both late endosomal and lysosomal markers. J. Biol. Chem., 272: 25339-25344, 1997.
    • (1997) J. Biol. Chem. , vol.272 , pp. 25339-25344
    • Molinari, M.1    Galli, C.2    Norais, N.3    Telford, J.L.4    Rappuoli, R.5    Luzio, J.P.6    Montecucco, C.7
  • 19
    • 0030663325 scopus 로고    scopus 로고
    • Helicobacter pylori vacuolating toxin accumulates within the endosomal-vacuolar compartment of cultured gastric cells and potentiates the vacuolating activity of ammonia
    • Ricci, V., Sommi, P., Fiocca, R., Romano, M., Solcia. E., and Ventura, U. Helicobacter pylori vacuolating toxin accumulates within the endosomal-vacuolar compartment of cultured gastric cells and potentiates the vacuolating activity of ammonia. J. Pathol., 183: 453-459, 1997.
    • (1997) J. Pathol. , vol.183 , pp. 453-459
    • Ricci, V.1    Sommi, P.2    Fiocca, R.3    Romano, M.4    Solcia, E.5    Ventura, U.6
  • 20
    • 0031751816 scopus 로고    scopus 로고
    • Persistence of Helicobacter pylori VacA toxin and vacuolating potential in cultured gastric epithelial cells
    • Sommi, P., Ricci, V., Fiocca, R., Necchi, V., Romano, M., Telford, J. L., Solcia, E., and Ventura, U. Persistence of Helicobacter pylori VacA toxin and vacuolating potential in cultured gastric epithelial cells. Am. J. Physiol., 275: G681-G688, 1998.
    • (1998) Am. J. Physiol. , vol.275
    • Sommi, P.1    Ricci, V.2    Fiocca, R.3    Necchi, V.4    Romano, M.5    Telford, J.L.6    Solcia, E.7    Ventura, U.8
  • 21
    • 0033929821 scopus 로고    scopus 로고
    • Acid activation of Helicobacter pylori vacuolating cytotoxin (VacA) results in toxin internalization by eukaryotic cells
    • McClain, M. S., Schraw, W., Ricci, V., Boquet, P., and Cover, T. L. Acid activation of Helicobacter pylori vacuolating cytotoxin (VacA) results in toxin internalization by eukaryotic cells. Mol. Microbiol., 37: 433-442, 2000.
    • (2000) Mol. Microbiol. , vol.37 , pp. 433-442
    • McClain, M.S.1    Schraw, W.2    Ricci, V.3    Boquet, P.4    Cover, T.L.5
  • 22
    • 0029059733 scopus 로고
    • Mosaicism in vacuolating cytotoxin alleles of Helicobacter pylori. Association of specific vacA types with cytotoxin production and peptic ulceration
    • Atherton, J. C., Cao, P., Peek, R. M., Jr., Tummuru, M. K., Blaser, M. I., and Cover, T. L. Mosaicism in vacuolating cytotoxin alleles of Helicobacter pylori. Association of specific vacA types with cytotoxin production and peptic ulceration. J. Biol. Chem., 270: 17771-17777, 1995.
    • (1995) J. Biol. Chem. , vol.270 , pp. 17771-17777
    • Atherton, J.C.1    Cao, P.2    Peek R.M., Jr.3    Tummuru, M.K.4    Blaser, M.I.5    Cover, T.L.6
  • 25
    • 0034043635 scopus 로고    scopus 로고
    • Natural diversity in the N terminus of the mature vacuolating cytotoxin of Helicobacter pylori determines cytotoxin activity
    • Letley, D. P., and Atherton, J. C. Natural diversity in the N terminus of the mature vacuolating cytotoxin of Helicobacter pylori determines cytotoxin activity. J. Bacteriol., 182: 3278-3280, 2000.
    • (2000) J. Bacteriol. , vol.182 , pp. 3278-3280
    • Letley, D.P.1    Atherton, J.C.2
  • 26
    • 0034750730 scopus 로고    scopus 로고
    • A 12-amino-acid segment, present in type s2 but not type s1 Helicobacter pylori VacA proteins, abolishes cytotoxin activity and alters membrane channel formation
    • McClain, M. S., Cao, P., Iwamoto, H., Vinion-Dubiel, A. D., Szabo, G., Shao, Z., and Cover, T. L. A 12-amino-acid segment, present in type s2 but not type s1 Helicobacter pylori VacA proteins, abolishes cytotoxin activity and alters membrane channel formation. J. Bacteriol., 183: 6499-6508, 2001.
    • (2001) J. Bacteriol. , vol.183 , pp. 6499-6508
    • McClain, M.S.1    Cao, P.2    Iwamoto, H.3    Vinion-Dubiel, A.D.4    Szabo, G.5    Shao, Z.6    Cover, T.L.7
  • 29
    • 0035664426 scopus 로고    scopus 로고
    • The relationship between Helicobacter pylori infection, the virulence genotypes of the infecting strain and gastric cancer in the African setting
    • Louw, J. A., Kidd, M. S., Kummer, A. F., Taylor, K., Kotze, U., and Hanslo, D. The relationship between Helicobacter pylori infection, the virulence genotypes of the infecting strain and gastric cancer in the African setting. Helicobacter, 6: 268-273, 2001.
    • (2001) Helicobacter , vol.6 , pp. 268-273
    • Louw, J.A.1    Kidd, M.S.2    Kummer, A.F.3    Taylor, K.4    Kotze, U.5    Hanslo, D.6
  • 31
    • 0031032033 scopus 로고    scopus 로고
    • Clinical and pathological importance of heterogeneity in vacA, the vacuolating cytotoxin gene of Helicobacter pylori
    • Atherton, J. C., Peek, R. M., Jr., Tham, K. T., Cover, T. L., and Blaser, M. J. Clinical and pathological importance of heterogeneity in vacA, the vacuolating cytotoxin gene of Helicobacter pylori. Gastroenterology, 112: 92-99, 1997.
    • (1997) Gastroenterology , vol.112 , pp. 92-99
    • Atherton, J.C.1    Peek R.M., Jr.2    Tham, K.T.3    Cover, T.L.4    Blaser, M.J.5
  • 32
    • 0029080739 scopus 로고
    • Role of the Helicobacter pylori virulence factors vacuolating cytotoxin, CagA, and urease in a mouse model of disease
    • Ghiara, P., Marchetti, M., Blaser, M. J., Tummuru, M. K., Cover, T. L., Segal, E. D., Tompkins, L. S., and Rappuoli, R. Role of the Helicobacter pylori virulence factors vacuolating cytotoxin, CagA, and urease in a mouse model of disease. Infect. Immun., 63: 4154-4160, 1995.
    • (1995) Infect. Immun. , vol.63 , pp. 4154-4160
    • Ghiara, P.1    Marchetti, M.2    Blaser, M.J.3    Tummuru, M.K.4    Cover, T.L.5    Segal, E.D.6    Tompkins, L.S.7    Rappuoli, R.8
  • 33
    • 0029987967 scopus 로고    scopus 로고
    • Induction of gastric epithelial apoptosis by Helicobacter pylori
    • Moss, S. F., Calam, J., Agarwal, B., Wang, S., and Holt, P. R. Induction of gastric epithelial apoptosis by Helicobacter pylori. Gut, 38: 498-501, 1996.
    • (1996) Gut , vol.38 , pp. 498-501
    • Moss, S.F.1    Calam, J.2    Agarwal, B.3    Wang, S.4    Holt, P.R.5
  • 34
    • 8944241770 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase, nitrotyrosine, and apoptosis in Helicobacter pylori gastritis: Effect of antibiotics and antioxidants
    • Mannick, E. E., Bravo, L. E., Zarama, G., Realpe, J. L., Zhang, X. J., Ruiz, B., Fontham, E. T., Mera, R., Miller, M. J., and Correa, P. Inducible nitric oxide synthase, nitrotyrosine, and apoptosis in Helicobacter pylori gastritis: effect of antibiotics and antioxidants. Cancer Res., 56: 3238-3243, 1996.
    • (1996) Cancer Res. , vol.56 , pp. 3238-3243
    • Mannick, E.E.1    Bravo, L.E.2    Zarama, G.3    Realpe, J.L.4    Zhang, X.J.5    Ruiz, B.6    Fontham, E.T.7    Mera, R.8    Miller, M.J.9    Correa, P.10
  • 35
    • 0030668211 scopus 로고    scopus 로고
    • Increase in proliferation and apoptosis of gastric epithelial cells early in the natural history of Helicobacter pylori infection
    • Jones, N. L., Shannon, P. T., Cutz, E., Yeger, H., and Sherman, P. M. Increase in proliferation and apoptosis of gastric epithelial cells early in the natural history of Helicobacter pylori infection. Am. J. Pathol., 151: 1695-1703, 1997.
    • (1997) Am. J. Pathol. , vol.151 , pp. 1695-1703
    • Jones, N.L.1    Shannon, P.T.2    Cutz, E.3    Yeger, H.4    Sherman, P.M.5
  • 36
    • 0032532381 scopus 로고    scopus 로고
    • Involvement of the CD95 (APO-1/Fas) receptor and ligand system in Helicobacter pylori-induced gastric epithelial apoptosis
    • Rudi, J., Kuck, D., Strand, S., von Herbay, A., Mariani, S. M., Krammer, P. H., Galle, P. R., and Stremmel, W. Involvement of the CD95 (APO-1/Fas) receptor and ligand system in Helicobacter pylori-induced gastric epithelial apoptosis. J. Clin. Investig., 102: 1506-1514, 1998.
    • (1998) J. Clin. Investig. , vol.102 , pp. 1506-1514
    • Rudi, J.1    Kuck, D.2    Strand, S.3    Von Herbay, A.4    Mariani, S.M.5    Krammer, P.H.6    Galle, P.R.7    Stremmel, W.8
  • 37
    • 0031921970 scopus 로고    scopus 로고
    • Mice lacking secretory phospholipase A2 show altered apoptosis and differentiation with Helicobacter fells infection
    • Wang, T. C., Goldenring, J. R., Dangler, C., Ito, S., Mueller, A., Jeon, W. K., Koh, T. J., and Fox, J. G. Mice lacking secretory phospholipase A2 show altered apoptosis and differentiation with Helicobacter fells infection. Gastroenterology, 114: 675-689, 1998.
    • (1998) Gastroenterology , vol.114 , pp. 675-689
    • Wang, T.C.1    Goldenring, J.R.2    Dangler, C.3    Ito, S.4    Mueller, A.5    Jeon, W.K.6    Koh, T.J.7    Fox, J.G.8
  • 38
    • 0033831753 scopus 로고    scopus 로고
    • In vivo disruption of the Fas pathway abrogates gastric growth alterations secondary to Helicobacter infection
    • Houghton, J. M., Bloch, L. M., Goldstein, M., Von Hagen, S., and Korah, R. M. In vivo disruption of the Fas pathway abrogates gastric growth alterations secondary to Helicobacter infection. J. Infect. Dis., 182: 856-864, 2000.
    • (2000) J. Infect. Dis. , vol.182 , pp. 856-864
    • Houghton, J.M.1    Bloch, L.M.2    Goldstein, M.3    Von Hagen, S.4    Korah, R.M.5
  • 39
    • 0036117897 scopus 로고    scopus 로고
    • Enhanced disease severity in Helicobacter pylori-infected mice deficient in Fas signaling
    • Jones, N. L., Day, A. S., Jennings, H., Shannon, P. T., Galindo-Mata, E., and Sherman, P. M. Enhanced disease severity in Helicobacter pylori-infected mice deficient in Fas signaling. Infect. Immun., 70: 2591-2597, 2002.
    • (2002) Infect. Immun. , vol.70 , pp. 2591-2597
    • Jones, N.L.1    Day, A.S.2    Jennings, H.3    Shannon, P.T.4    Galindo-Mata, E.5    Sherman, P.M.6
  • 42
    • 0034663921 scopus 로고    scopus 로고
    • Helicobacter pylori urease binds to class II MHC on gastric epithelial cells and induces their apoptosis
    • Fan, X., Gunasena, H., Cheng, Z., Espejo, R., Crowe, S. E., Ernst, P. B., and Reyes, V. E. Helicobacter pylori urease binds to class II MHC on gastric epithelial cells and induces their apoptosis. J. Immunol., 165: 1918-1924, 2000.
    • (2000) J. Immunol. , vol.165 , pp. 1918-1924
    • Fan, X.1    Gunasena, H.2    Cheng, Z.3    Espejo, R.4    Crowe, S.E.5    Ernst, P.B.6    Reyes, V.E.7
  • 45
    • 0030773524 scopus 로고    scopus 로고
    • Regulation of gastric epithelial cell growth by Helicobacter pylori: Evidence for a major role of apoptosis
    • Wagner, S., Beil, W., Westermann, J., Logan, R. P., Bock, C. T., Trautwein, C., Bleck, J. S., and Manns, M. P. Regulation of gastric epithelial cell growth by Helicobacter pylori: evidence for a major role of apoptosis. Gastroenterology, 113: 1836-1847, 1997.
    • (1997) Gastroenterology , vol.113 , pp. 1836-1847
    • Wagner, S.1    Beil, W.2    Westermann, J.3    Logan, R.P.4    Bock, C.T.5    Trautwein, C.6    Bleck, J.S.7    Manns, M.P.8
  • 46
    • 0032783147 scopus 로고    scopus 로고
    • Helicobacter pylori induces gastric epithelial cell apoptosis in association with increased Fas receptor expression
    • Jones, N. L., Day, A. S., Jennings, H. A., and Sherman, P. M. Helicobacter pylori induces gastric epithelial cell apoptosis in association with increased Fas receptor expression. Infect. Immun., 67: 4237-4242, 1999.
    • (1999) Infect. Immun. , vol.67 , pp. 4237-4242
    • Jones, N.L.1    Day, A.S.2    Jennings, H.A.3    Sherman, P.M.4
  • 47
    • 0032987480 scopus 로고    scopus 로고
    • Apoptosis in Helicobacter pylori-associated gastric and duodenal ulcer disease is mediated via the Fas antigen pathway
    • Houghton, J., Korah, R. M., Condon, M. R., and Kim, K. H. Apoptosis in Helicobacter pylori-associated gastric and duodenal ulcer disease is mediated via the Fas antigen pathway. Dig. Dis. Sci., 44: 465-478, 1999.
    • (1999) Dig. Dis. Sci. , vol.44 , pp. 465-478
    • Houghton, J.1    Korah, R.M.2    Condon, M.R.3    Kim, K.H.4
  • 48
    • 0035903124 scopus 로고    scopus 로고
    • Activation of peroxisome proliferator-activated receptor gamma suppresses nuclear factor κB-mediated apoptosis induced by Helicobacter pylori in gastric epithelial cells
    • Gupta, R. A., Polk, D. B., Krishna, U., Israel, D. A., Yan, F., DuBois, R. N., and Peek, R. M., Jr. Activation of peroxisome proliferator-activated receptor gamma suppresses nuclear factor κB-mediated apoptosis induced by Helicobacter pylori in gastric epithelial cells. J. Biol. Chem., 276: 31059-31066, 2001.
    • (2001) J. Biol. Chem. , vol.276 , pp. 31059-31066
    • Gupta, R.A.1    Polk, D.B.2    Krishna, U.3    Israel, D.A.4    Yan, F.5    DuBois, R.N.6    Peek R.M., Jr.7
  • 49
    • 0034923765 scopus 로고    scopus 로고
    • Vacuolating cytotoxin of Helicobacter pylori induces apoptosis in the human gastric epithelial cell line AGS
    • Kuck, D., Kolmerer, B., Iking-Konert, C., Krammer, P. H., Stremmel, W., and Rudi, J. Vacuolating cytotoxin of Helicobacter pylori induces apoptosis in the human gastric epithelial cell line AGS. Infect. Immun., 69: 5080-5087, 2001.
    • (2001) Infec. Immun. , vol.69 , pp. 5080-5087
    • Kuck, D.1    Kolmerer, B.2    Iking-Konert, C.3    Krammer, P.H.4    Stremmel, W.5    Rudi, J.6
  • 50
    • 0030809535 scopus 로고    scopus 로고
    • Acid-induced dissociation of VacA, the Helicobacter pylori vacuolating cytotoxin, reveals its pattern of assembly
    • Cover, T. L., Hanson, P. I., and Heuser, J. E. Acid-induced dissociation of VacA, the Helicobacter pylori vacuolating cytotoxin, reveals its pattern of assembly. J. Cell Biol., 138: 759-769, 1997.
    • (1997) J. Cell Biol. , vol.138 , pp. 759-769
    • Cover, T.L.1    Hanson, P.I.2    Heuser, J.E.3
  • 51
    • 0033515072 scopus 로고    scopus 로고
    • The vacuolating toxin from Helicobacter pylori forms hexameric pores in lipid bilayers at low pH
    • Czajkowsky, D. M., Iwamoto, H., Cover, T. L., and Shao, Z. The vacuolating toxin from Helicobacter pylori forms hexameric pores in lipid bilayers at low pH. Proc. Natl. Acad. Sci. USA, 96: 2001-2006, 1999.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 2001-2006
    • Czajkowsky, D.M.1    Iwamoto, H.2    Cover, T.L.3    Shao, Z.4
  • 53
    • 0028064605 scopus 로고
    • A urease-negative mutant of Helicobacter pylori constructed by allelic exchange mutagenesis lacks the ability to colonize the nude mouse stomach
    • Tsuda, T., Karita, M., Morshed, M. G., Okita, K., and Nakazawa, T. A urease-negative mutant of Helicobacter pylori constructed by allelic exchange mutagenesis lacks the ability to colonize the nude mouse stomach. Infect. Immun., 62: 3586-3589, 1994.
    • (1994) Infect. Immun. , vol.62 , pp. 3586-3589
    • Tsuda, T.1    Karita, M.2    Morshed, M.G.3    Okita, K.4    Nakazawa, T.5
  • 55
    • 0031814273 scopus 로고    scopus 로고
    • Heterogeneity in levels of vacuolating cytotoxin gene (vacA) transcription among Helicobacter pylori strains
    • Forsyth, M. H., Atherton, J. C., Blaser, M. J., and Cover, T. L. Heterogeneity in levels of vacuolating cytotoxin gene (vacA) transcription among Helicobacter pylori strains. Infect. Immun., 66: 3088-3094, 1998.
    • (1998) Infect. Immun. , vol.66 , pp. 3088-3094
    • Forsyth, M.H.1    Atherton, J.C.2    Blaser, M.J.3    Cover, T.L.4
  • 59
    • 0033199366 scopus 로고    scopus 로고
    • Increase in apoptosis and decrease in omithine decarboxylase activity of the gastric mucosa in patients with atrophic gastritis and gastric ulcer after successful eradication of Helicobacter pylori
    • Hirasawa, R., Tatsuta, M., Iishi, H., Yano, H., Baba, M., Uedo, N., and Sakai, N. Increase in apoptosis and decrease in omithine decarboxylase activity of the gastric mucosa in patients with atrophic gastritis and gastric ulcer after successful eradication of Helicobacter pylori. Am. J. Gastroenterol., 94: 2398-2402, 1999.
    • (1999) Am. J. Gastroenterol. , vol.94 , pp. 2398-2402
    • Hirasawa, R.1    Tatsuta, M.2    Iishi, H.3    Yano, H.4    Baba, M.5    Uedo, N.6    Sakai, N.7
  • 60
    • 0030772159 scopus 로고    scopus 로고
    • Helicobacter pylori infection activates NF-κB in gastric epithelial cells
    • Keates, S., Hitti, Y. S., Upton, M., and Kelly, C. P. Helicobacter pylori infection activates NF-κB in gastric epithelial cells. Gastroenterology, 113: 1099-1109, 1997.
    • (1997) Gastroenterology , vol.113 , pp. 1099-1109
    • Keates, S.1    Hitti, Y.S.2    Upton, M.3    Kelly, C.P.4
  • 61
    • 0032030668 scopus 로고    scopus 로고
    • Activation of IL-8 gene expression by Helicobacter pylori is regulated by transcription factor nuclear factor-κB in gastric epithelial cells
    • Sharma, S. A., Tummuru, M. K., Blaser, M. J, and Kerr, L. D. Activation of IL-8 gene expression by Helicobacter pylori is regulated by transcription factor nuclear factor-κB in gastric epithelial cells. J. Immunol., 160: 2401-2407, 1998.
    • (1998) J. Immunol. , vol.160 , pp. 2401-2407
    • Sharma, S.A.1    Tummuru, M.K.2    Blaser, M.J.3    Kerr, L.D.4
  • 62
    • 0034235373 scopus 로고    scopus 로고
    • pylori activates NF-κB through a signaling pathway involving IκB kinases. NF-κB-inducing kinase, TRAF2, and TRAF6 in gastric cancer cells
    • Maeda, S., Yoshida, H., Ogura, K., Mitsuno, Y., Hirata, Y., Yamaji, Y., Akanuma, M., Shiratori, Y., and Omata, M. H. pylori activates NF-κB through a signaling pathway involving IκB kinases. NF-κB-inducing kinase, TRAF2, and TRAF6 in gastric cancer cells. Gastroenterology, 119: 97-108, 2000.
    • (2000) Gastroenterology , vol.119 , pp. 97-108
    • Maeda, S.1    Yoshida, H.2    Ogura, K.3    Mitsuno, Y.4    Hirata, Y.5    Yamaji, Y.6    Akanuma, M.7    Shiratori, Y.8    Omata, M.H.9
  • 63
    • 0028966547 scopus 로고
    • Mucosal interleukin-8 and Helicobacter pylori-associated gastroduodenal disease
    • Crabtree, J. E., and Lindley, I. J. Mucosal interleukin-8 and Helicobacter pylori-associated gastroduodenal disease. Eur. J. Gastroenterol. Hepatol., 6 (Suppl. 1): S33-S38, 1994.
    • (1994) Eur. J. Gastroenterol. Hepatol. , vol.6 , Issue.SUPPL. 1
    • Crabtree, J.E.1    Lindley, I.J.2
  • 66
    • 0035969249 scopus 로고    scopus 로고
    • α-toxin is a mediator of Staphylococcus aureus-induced cell death and activates caspases via the intrinsic death pathway independently of death receptor signaling
    • Bantel, H., Sinha, B., Domschke, W., Peters, G., Schulze-Osthoff, K., and Janicke, R. U. α-Toxin is a mediator of Staphylococcus aureus-induced cell death and activates caspases via the intrinsic death pathway independently of death receptor signaling. J. Cell Biol., 155: 637-648, 2001.
    • (2001) J. Cell Biol. , vol.155 , pp. 637-648
    • Bantel, H.1    Sinha, B.2    Domschke, W.3    Peters, G.4    Schulze-Osthoff, K.5    Janicke, R.U.6
  • 67
    • 0035142645 scopus 로고    scopus 로고
    • Ammonia as an accelerator of tumor necrosis factor alpha-induced apoptosis of gastric epithelial cells in Helicobacter pylori infection
    • Igarashi, M., Kitada, Y., Yoshiyama, H., Takagi, A., Miwa, T., and Koga, Y. Ammonia as an accelerator of tumor necrosis factor alpha-induced apoptosis of gastric epithelial cells in Helicobacter pylori infection. Infect. Immun., 69: 816-821, 2001.
    • (2001) Infect. Immun. , vol.69 , pp. 816-821
    • Igarashi, M.1    Kitada, Y.2    Yoshiyama, H.3    Takagi, A.4    Miwa, T.5    Koga, Y.6
  • 69
    • 0025369322 scopus 로고
    • Purification and characterization of urease from Helicobacter pylori
    • Dunn, B. E., Campbell, G. P., Perez-Perez, G. I., and Blaser, M. J. Purification and characterization of urease from Helicobacter pylori. J. Biol. Chem., 265: 9464-9469, 1990.
    • (1990) J. Biol. Chem. , vol.265 , pp. 9464-9469
    • Dunn, B.E.1    Campbell, G.P.2    Perez-Perez, G.I.3    Blaser, M.J.4
  • 70
    • 0024499475 scopus 로고
    • Association of Campylobacter pylori with induced expression of class II transplantation antigens on gastric epithelial cells
    • Engstrand, L., Scheynius, A., Pahlson, C., Grimelius, L., Schwan, A., and Gustavsson, S. Association of Campylobacter pylori with induced expression of class II transplantation antigens on gastric epithelial cells. Infect. Immun., 57: 827-832, 1989.
    • (1989) Infect. Immun. , vol.57 , pp. 827-832
    • Engstrand, L.1    Scheynius, A.2    Pahlson, C.3    Grimelius, L.4    Schwan, A.5    Gustavsson, S.6
  • 71
    • 0033933205 scopus 로고    scopus 로고
    • Helicobacter pylori modulates lymphoepithelial cell interactions leading to epithelial cell damage through Fas/Fas ligand interactions
    • Wang, J., Fan, X., Lindholm, C., Bennett, M., O'Connoll, J., Shanahan, F., Brooks, E. G., Reyes, V. E., and Ernst, P. B. Helicobacter pylori modulates lymphoepithelial cell interactions leading to epithelial cell damage through Fas/Fas ligand interactions. Infect. Immun., 68: 4303-4311, 2000.
    • (2000) Infect. Immun. , vol.68 , pp. 4303-4311
    • Wang, J.1    Fan, X.2    Lindholm, C.3    Bennett, M.4    O'Connoll, J.5    Shanahan, F.6    Brooks, E.G.7    Reyes, V.E.8    Ernst, P.B.9
  • 72
    • 0034661646 scopus 로고    scopus 로고
    • Helicobacter pylori-induced mucosal inflammation is Th1 mediated and exacerbated in IL-4, but not IFN-γ, gene-deficient mice
    • Smythies, L. E., Waites, K. B., Lindsey, J. R., Harris, P. R., Ghiara, P., and Smith, P. D. Helicobacter pylori-induced mucosal inflammation is Th1 mediated and exacerbated in IL-4, but not IFN-γ, gene-deficient mice. J. Immunol., 165: 1022-1029, 2000.
    • (2000) J. Immunol. , vol.165 , pp. 1022-1029
    • Smythies, L.E.1    Waites, K.B.2    Lindsey, J.R.3    Harris, P.R.4    Ghiara, P.5    Smith, P.D.6
  • 73
    • 0028326795 scopus 로고
    • Mucosal tumor necrosis factor-αs, interleukin-1β, and interleukin-8 production in patients with Helicobacter pylori infection
    • Noach, L. A., Bosma, N. B., Jansen, J., Hoek, F. J., van Deventer, S. J., and Tytgat, G. N. Mucosal tumor necrosis factor-αs, interleukin-1β, and interleukin-8 production in patients with Helicobacter pylori infection. Scand. J. Gastroenterol., 29: 425-429, 1994.
    • (1994) Scand. J. Gastroenterol. , vol.29 , pp. 425-429
    • Noach, L.A.1    Bosma, N.B.2    Jansen, J.3    Hoek, F.J.4    Van Deventer, S.J.5    Tytgat, G.N.6
  • 76
    • 0031929816 scopus 로고    scopus 로고
    • Carcinogenesis, apoptosis and cell proliferation
    • Correa, P., and Miller, M. J. Carcinogenesis, apoptosis and cell proliferation. Br. Med. Bull., 54: 151-162, 1998.
    • (1998) Br. Med. Bull. , vol.54 , pp. 151-162
    • Correa, P.1    Miller, M.J.2


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