Reconstitution of helicobacter pylori VacA toxin from purified components

Biochemistry

Volumn 49, Issue 27, 2010, Pages 5743-5752

  González Rivera, Christian ^a   Gangwer, Kelly A ^a   McClain, Mark S ^b   Eli, Ilyas M ^a   Chambers, Melissa G ^a   Ohi, Melanie D ^a   Lacy, D Borden ^a   Cover, Timothy L ^a,b  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Department of Medicine ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL BINDING; CRYO-ELECTRON MICROSCOPY; DENATURING CONDITIONS; FLOWER-SHAPED; GASTRIC CANCERS; HELA CELL; HELICOBACTER PYLORI; HOST CELLS; HUMAN CELLS; JURKAT CELL; OPTIMIZED CONDITIONS; PEPTIC ULCER DISEASE; PORE FORMING TOXINS; REFOLDING; ROD-SHAPED; SOLUBLE PROTEINS; TWO DOMAINS; X RAY CRYSTAL STRUCTURES;

BINDING ENERGY; CRYSTAL STRUCTURE; ELECTRON MICROSCOPES; MONOMERS; OLIGOMERIZATION; OLIGOMERS; PURIFICATION; TOXIC MATERIALS;

SIZE EXCLUSION CHROMATOGRAPHY;

DETERGENT; INTERLEUKIN 2; OLIGOMER; PROTEIN P33; PROTEIN P55; RECOMBINANT PROTEIN; VACUOLATING TOXIN; ANTINEOPLASTIC AGENT; CYCLOPHOSPHAMIDE; DACTINOMYCIN; DOXORUBICIN; TOXIN; VACA PROTOCOL; VINCRISTINE;

ARTICLE; CELL VACUOLE; CYTOKINE PRODUCTION; HELA CELL; HELICOBACTER PYLORI; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; NONHUMAN; NUCLEOTIDE SEQUENCE; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN STRUCTURE; STRUCTURE ANALYSIS; CRYOELECTRON MICROSCOPY; GENETICS; METABOLISM; X RAY;

HELICOBACTER PYLORI;

ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CRYOELECTRON MICROSCOPY; CYCLOPHOSPHAMIDE; DACTINOMYCIN; DOXORUBICIN; HELA CELLS; HELICOBACTER PYLORI; HUMANS; INTERLEUKIN-2; TOXINS, BIOLOGICAL; VINCRISTINE; X-RAYS;

EID: 77954702594     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi100618g     Document Type: Article

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