메뉴 건너뛰기




Volumn 111, Issue 2, 2004, Pages 173-178

Toll-like receptor 2 (TLR2) and TLR4 are present inside human dendritic cells, associated with microtubules and the Golgi apparatus but are not detectable on the cell surface: Integrity of microtubules is required for interleukin-12 production in response to internalized bacteria

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TUBULIN; INTERLEUKIN 12; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4;

EID: 0842265548     PISSN: 00192805     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.0019-2805.2003.01803.x     Document Type: Article
Times cited : (98)

References (32)
  • 1
    • 0032956004 scopus 로고    scopus 로고
    • Dendritic cells: A link between innate and adaptive immunity
    • Palucka K, Banchereau J. Dendritic cells: a link between innate and adaptive immunity. J Clin Immunol 1999; 19:12-25.
    • (1999) J Clin Immunol , vol.19 , pp. 12-25
    • Palucka, K.1    Banchereau, J.2
  • 3
    • 0035150620 scopus 로고    scopus 로고
    • The Toll receptor family
    • Muzio M, Mantovani A. The Toll receptor family. Allergy 2001; 56:103-8.
    • (2001) Allergy , vol.56 , pp. 103-108
    • Muzio, M.1    Mantovani, A.2
  • 4
    • 0033213590 scopus 로고    scopus 로고
    • Differential roles of TLR2 and TLR4 in recognition of Gram-negative and Gram-positive bacterial cell wall components
    • Takeuchi O, Hoshino K, Kawai T, Sanjo H, Takada H, Ogawa T, Takeda K, Akira S. Differential roles of TLR2 and TLR4 in recognition of Gram-negative and Gram-positive bacterial cell wall components. Immunity 1999; 11:443-51.
    • (1999) Immunity , vol.11 , pp. 443-451
    • Takeuchi, O.1    Hoshino, K.2    Kawai, T.3    Sanjo, H.4    Takada, H.5    Ogawa, T.6    Takeda, K.7    Akira, S.8
  • 5
    • 0036134963 scopus 로고    scopus 로고
    • Toll-like receptors: How they work and what they do
    • Beutler B. Toll-like receptors: how they work and what they do. Curr Opin Hematol 2002; 9:2-10.
    • (2002) Curr Opin Hematol , vol.9 , pp. 2-10
    • Beutler, B.1
  • 6
    • 0033198204 scopus 로고    scopus 로고
    • Cutting edge: Inflammatory signaling by Borrelia burgdorferi lipoproteins is mediated by toll-like receptor 2
    • Hirschfeld M, Kirschning CJ, Schwandner R, Wesche H, Weis JH, Wooten RM, Weis JJ. Cutting edge: inflammatory signaling by Borrelia burgdorferi lipoproteins is mediated by toll-like receptor 2. J Immunol 1999; 163:2382-6.
    • (1999) J Immunol , vol.163 , pp. 2382-2386
    • Hirschfeld, M.1    Kirschning, C.J.2    Schwandner, R.3    Wesche, H.4    Weis, J.H.5    Wooten, R.M.6    Weis, J.J.7
  • 7
    • 0033618562 scopus 로고    scopus 로고
    • Host defense mechanisms triggered by microbial lipoproteins through toll-like receptors
    • Brightbill HD, Libraty DH, Krutzik SR et al. Host defense mechanisms triggered by microbial lipoproteins through toll-like receptors. Science 1999; 285:732-6.
    • (1999) Science , vol.285 , pp. 732-736
    • Brightbill, H.D.1    Libraty, D.H.2    Krutzik, S.R.3
  • 10
    • 0035170049 scopus 로고    scopus 로고
    • A lipopolysaccharide-deficient mutant of Neisseria meningitidis elicits attenuated cytokine release by human macrophages and signals via toll-like receptor (TLR) 2 but not via TLR4/MD2
    • Pridmore AC, Wyllie DH, Abdillahi F, Steeghs L, van der Ley P, Dower SK, Read RC. A lipopolysaccharide-deficient mutant of Neisseria meningitidis elicits attenuated cytokine release by human macrophages and signals via toll-like receptor (TLR) 2 but not via TLR4/MD2. J Infect Dis 2001; 183:89-96.
    • (2001) J Infect Dis , vol.183 , pp. 89-96
    • Pridmore, A.C.1    Wyllie, D.H.2    Abdillahi, F.3    Steeghs, L.4    Van Der Ley, P.5    Dower, S.K.6    Read, R.C.7
  • 11
    • 0034461988 scopus 로고    scopus 로고
    • Differential roles of TLR2 and TLR4 in the host response to Gram-negative bacteria: Lessons from a lipopolysaccharide-deficient mutant of Neisseria meningitidis
    • Ingalls RR, Lien E, Golenbock DT. Differential roles of TLR2 and TLR4 in the host response to Gram-negative bacteria: lessons from a lipopolysaccharide- deficient mutant of Neisseria meningitidis. J Endotoxin Res 2000; 6:411-15.
    • (2000) J Endotoxin Res , vol.6 , pp. 411-415
    • Ingalls, R.R.1    Lien, E.2    Golenbock, D.T.3
  • 12
    • 0034976591 scopus 로고    scopus 로고
    • Dendritic cell activation and cytokine production induced by group B Neisseria meningitidis: Interleukin-12 production depends on lipopolysaccharide expression in intact bacteria
    • Dixon GL, Newton PJ, Chain BM et al Dendritic cell activation and cytokine production induced by group B Neisseria meningitidis: interleukin-12 production depends on lipopolysaccharide expression in intact bacteria. Infect Immun 2001; 69:4351-7.
    • (2001) Infect Immun , vol.69 , pp. 4351-4357
    • Dixon, G.L.1    Newton, P.J.2    Chain, B.M.3
  • 14
    • 0036318851 scopus 로고    scopus 로고
    • Bacterial CpG-DNA and lipopolysaccharides activate Toll-like receptors at distinct cellular compartments
    • Ahmad-Nejad P, Hacker H, Rutz M, Bauer S, Vabulas RM, Wagner H. Bacterial CpG-DNA and lipopolysaccharides activate Toll-like receptors at distinct cellular compartments. Eur J Immunol 2002; 32:1958-68.
    • (2002) Eur J Immunol , vol.32 , pp. 1958-1968
    • Ahmad-Nejad, P.1    Hacker, H.2    Rutz, M.3    Bauer, S.4    Vabulas, R.M.5    Wagner, H.6
  • 15
    • 0037018107 scopus 로고    scopus 로고
    • Toll-like receptor 4 resides in the Golgi apparatus and colocalizes with internalized lipopolysaccharide in intestinal epithelial cells
    • Hornef MW, Frisan T, Vandewalle A, Normark S, Richter-Dahlfors A. Toll-like receptor 4 resides in the Golgi apparatus and colocalizes with internalized lipopolysaccharide in intestinal epithelial cells. J Exp Med 2002; 195:559-70.
    • (2002) J Exp Med , vol.195 , pp. 559-570
    • Hornef, M.W.1    Frisan, T.2    Vandewalle, A.3    Normark, S.4    Richter-Dahlfors, A.5
  • 16
    • 0037033073 scopus 로고    scopus 로고
    • Lipopolysaccharide rapidly traffics to and from the Golgi apparatus with the Toll-like receptor 4-MD-2-CD14 complex in a process that is distinct from the initiation of signal transduction
    • Latz E, Visintin A, Lien E, Fitzgerald KA, Monks BG, Kurt-Jones EA, Golenbock DT, Espevik T. Lipopolysaccharide rapidly traffics to and from the Golgi apparatus with the Toll-like receptor 4-MD-2-CD14 complex in a process that is distinct from the initiation of signal transduction. J Biol Chem 2002; 277:47834-43.
    • (2002) J Biol Chem , vol.277 , pp. 47834-47843
    • Latz, E.1    Visintin, A.2    Lien, E.3    Fitzgerald, K.A.4    Monks, B.G.5    Kurt-Jones, E.A.6    Golenbock, D.T.7    Espevik, T.8
  • 17
    • 0028289244 scopus 로고
    • Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/ macrophage colony-stimulating factor plus interleukin 4 and down-regulated by tumor necrosis factor alpha
    • Sallusto F, Lanzavecchia A. Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/ macrophage colony-stimulating factor plus interleukin 4 and down-regulated by tumor necrosis factor alpha. J Exp Med 1994; 179:1109-18.
    • (1994) J Exp Med , vol.179 , pp. 1109-1118
    • Sallusto, F.1    Lanzavecchia, A.2
  • 19
    • 0024369960 scopus 로고    scopus 로고
    • 1989 Definition of individual components within the cytoskeleton of Trypanosoma brucei by a library of monoclonal antibodies
    • Woods A, Sherwin T, Sasse R, MacRae TH, Baines AJ, Gull K 1989 Definition of individual components within the cytoskeleton of Trypanosoma brucei by a library of monoclonal antibodies. J Cell Sci 2002; 93:491-500.
    • (2002) J Cell Sci , vol.93 , pp. 491-500
    • Woods, A.1    Sherwin, T.2    Sasse, R.3    MacRae, T.H.4    Baines, A.J.5    Gull, K.6
  • 20
    • 0034705287 scopus 로고    scopus 로고
    • Sorting and signaling at the Golgi complex
    • Donaldson JG, Lippincott-Schwartz J. Sorting and signaling at the Golgi complex. Cell 2000; 101:693-6.
    • (2000) Cell , vol.101 , pp. 693-696
    • Donaldson, J.G.1    Lippincott-Schwartz, J.2
  • 21
    • 0036024988 scopus 로고    scopus 로고
    • Depolymerization of microtubules by colcemid induces the formation of elongated and centriole-nonassociated striated rootlets in PtK(2) cells
    • Hagiwara H, Takata K. Depolymerization of microtubules by colcemid induces the formation of elongated and centriole-nonassociated striated rootlets in PtK(2) cells. Cell Tissue Res 2002; 309:287-92.
    • (2002) Cell Tissue Res , vol.309 , pp. 287-292
    • Hagiwara, H.1    Takata, K.2
  • 22
    • 0037080024 scopus 로고    scopus 로고
    • Tissue expression of human Toll-like receptors and differential regulation of Toll-like receptor mRNAs in leukocytes in response to microbes, their products, and cytokines
    • Zarember KA, Godowski PJ. Tissue expression of human Toll-like receptors and differential regulation of Toll-like receptor mRNAs in leukocytes in response to microbes, their products, and cytokines. J Immunol 2002; 168:554-61.
    • (2002) J Immunol , vol.168 , pp. 554-561
    • Zarember, K.A.1    Godowski, P.J.2
  • 24
    • 0034123135 scopus 로고    scopus 로고
    • Differential expression and regulation of toll-like receptors (TLR) in human leukocytes: Selective expression of TLR3 in dendritic cells
    • Muzio M, Bosisio D, Polentarutti N et al. Differential expression and regulation of toll-like receptors (TLR) in human leukocytes: selective expression of TLR3 in dendritic cells. J Immunol 2000; 164:5998-6004.
    • (2000) J Immunol , vol.164 , pp. 5998-6004
    • Muzio, M.1    Bosisio, D.2    Polentarutti, N.3
  • 25
    • 0036569658 scopus 로고    scopus 로고
    • Toll-like receptor (TLR) 2 and TLR4 in human peripheral blood granulocytes: A critical role for monocytes in leukocyte lipopolysaccharide responses
    • Sabroe I, Jones EC, Usher LR, Whyte MK, Dower SK. Toll-like receptor (TLR) 2 and TLR4 in human peripheral blood granulocytes: a critical role for monocytes in leukocyte lipopolysaccharide responses. J Immunol 2002; 168:4701-10.
    • (2002) J Immunol , vol.168 , pp. 4701-4710
    • Sabroe, I.1    Jones, E.C.2    Usher, L.R.3    Whyte, M.K.4    Dower, S.K.5
  • 26
    • 0033575792 scopus 로고    scopus 로고
    • Transport of bacterial lipopolysaccharide to the Golgi apparatus
    • Thieblemont N, Wright SD. Transport of bacterial lipopolysaccharide to the Golgi apparatus. J Exp Med 1999; 190:523-34.
    • (1999) J Exp Med , vol.190 , pp. 523-534
    • Thieblemont, N.1    Wright, S.D.2
  • 27
    • 0346980722 scopus 로고    scopus 로고
    • Mice genetically hyporesponsive to lipopolysaccharide (LPS) exhibit a defect in endocytic uptake of LPS and ceramide
    • Thieblemont N, Wright SD. Mice genetically hyporesponsive to lipopolysaccharide (LPS) exhibit a defect in endocytic uptake of LPS and ceramide. J Exp Med 1997; 185:2095-100.
    • (1997) J Exp Med , vol.185 , pp. 2095-2100
    • Thieblemont, N.1    Wright, S.D.2
  • 29
    • 0037126598 scopus 로고    scopus 로고
    • Outer membrane composition of a lipopolysaccharide-deficient Neisseria meningitidis mutant
    • Steeghs L, de Cock H, Evers E, Zomer B, Tommassen J, Van Der LP. Outer membrane composition of a lipopolysaccharide-deficient Neisseria meningitidis mutant. EMBO J 2001; 20:6937-45.
    • (2001) EMBO J , vol.20 , pp. 6937-6945
    • Steeghs, L.1    De Cock, H.2    Evers, E.3    Zomer, B.4    Tommassen, J.5    Van Der, L.P.6
  • 30
    • 0024590613 scopus 로고
    • CR3 (CD11b/CD18) expresses one binding site for Arg-Gly-Asp-containing peptides and a second site for bacterial lipopolysaccharide
    • Wright SD, Levin SM, Jong MT, Chad Z, Kabbash LG. CR3 (CD11b/CD18) expresses one binding site for Arg-Gly-Asp-containing peptides and a second site for bacterial lipopolysaccharide. J Exp Med 1989; 169:175-83.
    • (1989) J Exp Med , vol.169 , pp. 175-183
    • Wright, S.D.1    Levin, S.M.2    Jong, M.T.3    Chad, Z.4    Kabbash, L.G.5
  • 32
    • 0038558249 scopus 로고    scopus 로고
    • Collaborative induction of inflammatory responses by dectin-1 and Toll-like receptor 2
    • Gantner BN, Simmons RM, Canavera SJ, Akira S, Underhill DM. Collaborative induction of inflammatory responses by dectin-1 and Toll-like receptor 2. J Exp Med 2003; 197:1107-17.
    • (2003) J Exp Med , vol.197 , pp. 1107-1117
    • Gantner, B.N.1    Simmons, R.M.2    Canavera, S.J.3    Akira, S.4    Underhill, D.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.