-
1
-
-
67650874081
-
Cancer statistics, 2009
-
Jemal A., Siegel R., Ward E., Hao Y., Xu J., Thun M.J. Cancer statistics, 2009. CA Cancer J Clin 2009, 59:225-249.
-
(2009)
CA Cancer J Clin
, vol.59
, pp. 225-249
-
-
Jemal, A.1
Siegel, R.2
Ward, E.3
Hao, Y.4
Xu, J.5
Thun, M.J.6
-
2
-
-
0034021690
-
Hypoxia, clonal selection, and the role of HIF-1 in tumor progression
-
Semenza G.L. Hypoxia, clonal selection, and the role of HIF-1 in tumor progression. Crit Rev Biochem Mol Biol 2000, 35:71-103.
-
(2000)
Crit Rev Biochem Mol Biol
, vol.35
, pp. 71-103
-
-
Semenza, G.L.1
-
3
-
-
10644234769
-
The role of hypoxia-induced factors in tumor progression
-
Vaupel P. The role of hypoxia-induced factors in tumor progression. Oncologist 2004, 9(Suppl. 5):10-17.
-
(2004)
Oncologist
, vol.9
, Issue.SUPPL. 5
, pp. 10-17
-
-
Vaupel, P.1
-
4
-
-
0037443587
-
Levels of hypoxia-inducible factor-1alpha independently predict prognosis in patients with lymph node negative breast carcinoma
-
Bos R., van der Groep P., Greijer A.E., et al. Levels of hypoxia-inducible factor-1alpha independently predict prognosis in patients with lymph node negative breast carcinoma. Cancer 2003, 97:1573-1581.
-
(2003)
Cancer
, vol.97
, pp. 1573-1581
-
-
Bos, R.1
van der Groep, P.2
Greijer, A.E.3
-
5
-
-
19944434232
-
Differential prognostic impact of hypoxia induced and diffuse HIF-1alpha expression in invasive breast cancer
-
Vleugel M.M., Greijer A.E., Shvarts A., et al. Differential prognostic impact of hypoxia induced and diffuse HIF-1alpha expression in invasive breast cancer. J Clin Pathol 2005, 58:172-177.
-
(2005)
J Clin Pathol
, vol.58
, pp. 172-177
-
-
Vleugel, M.M.1
Greijer, A.E.2
Shvarts, A.3
-
6
-
-
20244374424
-
Expression of hypoxia-inducible factor-1alpha in esophageal squamous cell carcinoma
-
Matsuyama T., Nakanishi K., Hayashi T., et al. Expression of hypoxia-inducible factor-1alpha in esophageal squamous cell carcinoma. Cancer Sci 2005, 96:176-182.
-
(2005)
Cancer Sci
, vol.96
, pp. 176-182
-
-
Matsuyama, T.1
Nakanishi, K.2
Hayashi, T.3
-
7
-
-
17644415725
-
Expression of hypoxia-inducible factor-1alpha protein predicts survival in patients with transitional cell carcinoma of the upper urinary tract
-
Nakanishi K., Hiroi S., Tominaga S., et al. Expression of hypoxia-inducible factor-1alpha protein predicts survival in patients with transitional cell carcinoma of the upper urinary tract. Clin Cancer Res 2005, 11:2583-2590.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 2583-2590
-
-
Nakanishi, K.1
Hiroi, S.2
Tominaga, S.3
-
8
-
-
0038282482
-
The hypoxia-inducible factor-1 alpha is a negative factor for tumor therapy
-
Unruh A., Ressel A., Mohamed H.G., et al. The hypoxia-inducible factor-1 alpha is a negative factor for tumor therapy. Oncogene 2003, 22:3213-3220.
-
(2003)
Oncogene
, vol.22
, pp. 3213-3220
-
-
Unruh, A.1
Ressel, A.2
Mohamed, H.G.3
-
9
-
-
0141956303
-
Overexpression of hypoxia-inducible-factor 1alpha(HIF-1alpha) in oesophageal squamous cell carcinoma correlates with lymph node metastasis and pathologic stage
-
Kurokawa T., Miyamoto M., Kato K., et al. Overexpression of hypoxia-inducible-factor 1alpha(HIF-1alpha) in oesophageal squamous cell carcinoma correlates with lymph node metastasis and pathologic stage. Br J Cancer 2003, 89:1042-1047.
-
(2003)
Br J Cancer
, vol.89
, pp. 1042-1047
-
-
Kurokawa, T.1
Miyamoto, M.2
Kato, K.3
-
11
-
-
0037480606
-
Hypoxic cervical cancers with low apoptotic index are highly aggressive
-
Hoeckel M., Schlenger K., Hoeckel S., Vaupel P. Hypoxic cervical cancers with low apoptotic index are highly aggressive. Cancer Res 1999, 59:4525-4528.
-
(1999)
Cancer Res
, vol.59
, pp. 4525-4528
-
-
Hoeckel, M.1
Schlenger, K.2
Hoeckel, S.3
Vaupel, P.4
-
12
-
-
0035677961
-
Treatment resistance of solid tumors: role of hypoxia and anemia
-
Vaupel P., Thews O., Hoeckel M. Treatment resistance of solid tumors: role of hypoxia and anemia. Med Oncol 2001, 18:243-259.
-
(2001)
Med Oncol
, vol.18
, pp. 243-259
-
-
Vaupel, P.1
Thews, O.2
Hoeckel, M.3
-
13
-
-
10644283057
-
Hypoxia and anemia: factors in decreased sensitivity to radiation therapy and chemotherapy?
-
Harrison L., Blackwell K. Hypoxia and anemia: factors in decreased sensitivity to radiation therapy and chemotherapy?. Oncologist 2004, 9(Suppl. 5):31-40.
-
(2004)
Oncologist
, vol.9
, Issue.SUPPL. 5
, pp. 31-40
-
-
Harrison, L.1
Blackwell, K.2
-
14
-
-
15244344783
-
Hypoxia-induced acidification causes mitoxantrone resistance not mediated by drug transporters in human breast cancer cells
-
Greijer A.E., de Jong M.C., Scheffer G.L., Shvarts A., van Diest P.J., van der Wall E. Hypoxia-induced acidification causes mitoxantrone resistance not mediated by drug transporters in human breast cancer cells. Cell Oncol 2005, 27:43-49.
-
(2005)
Cell Oncol
, vol.27
, pp. 43-49
-
-
Greijer, A.E.1
de Jong, M.C.2
Scheffer, G.L.3
Shvarts, A.4
van Diest, P.J.5
van der Wall, E.6
-
15
-
-
0027141149
-
Oxygen in human tumors: correlations between methods of measurement and response to therapy. Summary of a workshop held November 19-20, 1992, at the National Cancer Institute, Bethesda, Maryland
-
Stone H.B., Brown J.M., Phillips T.L., Sutherland R.M. Oxygen in human tumors: correlations between methods of measurement and response to therapy. Summary of a workshop held November 19-20, 1992, at the National Cancer Institute, Bethesda, Maryland. Radiat Res 1993, 136:422-434.
-
(1993)
Radiat Res
, vol.136
, pp. 422-434
-
-
Stone, H.B.1
Brown, J.M.2
Phillips, T.L.3
Sutherland, R.M.4
-
16
-
-
0036721256
-
Association of hypoxia-inducible factors 1alpha and 2alpha with activated angiogenic pathways and prognosis in patients with endometrial carcinoma
-
Sivridis E., Giatromanolaki A., Gatter K.C., Harris A.L., Koukourakis M.I. Association of hypoxia-inducible factors 1alpha and 2alpha with activated angiogenic pathways and prognosis in patients with endometrial carcinoma. Cancer 2002, 95:1055-1063.
-
(2002)
Cancer
, vol.95
, pp. 1055-1063
-
-
Sivridis, E.1
Giatromanolaki, A.2
Gatter, K.C.3
Harris, A.L.4
Koukourakis, M.I.5
-
17
-
-
0029753008
-
Activation of hypoxia-inducible transcription factor depends primarily upon redox-sensitive stabilization of its alpha subunit
-
Huang L.E., Arany Z., Livingston D.M., Bunn H.F. Activation of hypoxia-inducible transcription factor depends primarily upon redox-sensitive stabilization of its alpha subunit. J Biol Chem 1996, 271:32253-32259.
-
(1996)
J Biol Chem
, vol.271
, pp. 32253-32259
-
-
Huang, L.E.1
Arany, Z.2
Livingston, D.M.3
Bunn, H.F.4
-
18
-
-
0033233243
-
2 homeostasis by hypoxia-inducible factor 1
-
2 homeostasis by hypoxia-inducible factor 1. Annu Rev Cell Dev Biol 1999, 15:551-578.
-
(1999)
Annu Rev Cell Dev Biol
, vol.15
, pp. 551-578
-
-
Semenza, G.L.1
-
19
-
-
0032053169
-
Oxygen sensing, hypoxia-inducible factor-1 and the regulation of mammalian gene expression
-
Ratcliffe P.J., O'Rourke J.F., Maxwell P.H., Pugh C.W. Oxygen sensing, hypoxia-inducible factor-1 and the regulation of mammalian gene expression. J Exp Biol 1998, 201:1153-1162.
-
(1998)
J Exp Biol
, vol.201
, pp. 1153-1162
-
-
Ratcliffe, P.J.1
O'Rourke, J.F.2
Maxwell, P.H.3
Pugh, C.W.4
-
20
-
-
0034006016
-
HIF-1: mediator of physiological and pathophysiological responses to hypoxia
-
Semenza G.L. HIF-1: mediator of physiological and pathophysiological responses to hypoxia. J Appl Physiol 2000, 88:1474-1480.
-
(2000)
J Appl Physiol
, vol.88
, pp. 1474-1480
-
-
Semenza, G.L.1
-
21
-
-
21344438419
-
Up-regulation of gene expression by hypoxia is mediated predominantly by hypoxia-inducible factor 1 (HIF-1)
-
Greijer A.E., van der Groep P., Kemming D., et al. Up-regulation of gene expression by hypoxia is mediated predominantly by hypoxia-inducible factor 1 (HIF-1). J Pathol 2005, 206:291-304.
-
(2005)
J Pathol
, vol.206
, pp. 291-304
-
-
Greijer, A.E.1
van der Groep, P.2
Kemming, D.3
-
22
-
-
0036965605
-
Role of bicarbonate in the regulation of intracellular pH in the mammalian ventricular myocyte
-
Vaughan-Jones R.D., Spitzer K.W. Role of bicarbonate in the regulation of intracellular pH in the mammalian ventricular myocyte. Biochem Cell Biol 2002, 80:579-596.
-
(2002)
Biochem Cell Biol
, vol.80
, pp. 579-596
-
-
Vaughan-Jones, R.D.1
Spitzer, K.W.2
-
23
-
-
0028152377
-
Facilitative glucose transporters
-
Mueckler M. Facilitative glucose transporters. Eur J Biochem 1994, 219:713-725.
-
(1994)
Eur J Biochem
, vol.219
, pp. 713-725
-
-
Mueckler, M.1
-
24
-
-
0030044984
-
Vascular endothelial growth factor, a potent and selective angiogenic agent
-
Thomas K.A. Vascular endothelial growth factor, a potent and selective angiogenic agent. J Biol Chem 1996, 271:603-606.
-
(1996)
J Biol Chem
, vol.271
, pp. 603-606
-
-
Thomas, K.A.1
-
25
-
-
16644363476
-
HIF-1 and p53: communication of transcription factors under hypoxia
-
Schmid T., Zhou J., Brune B. HIF-1 and p53: communication of transcription factors under hypoxia. J Cell Mol Med 2004, 8:423-431.
-
(2004)
J Cell Mol Med
, vol.8
, pp. 423-431
-
-
Schmid, T.1
Zhou, J.2
Brune, B.3
-
26
-
-
13144275217
-
Dynamic balancing of the dual nature of HIF-1alpha for cell survival
-
Koshiji M., Huang L.E. Dynamic balancing of the dual nature of HIF-1alpha for cell survival. Cell Cycle 2004, 3:853-854.
-
(2004)
Cell Cycle
, vol.3
, pp. 853-854
-
-
Koshiji, M.1
Huang, L.E.2
-
27
-
-
0034693753
-
Met receptor tyrosine kinase: enhanced signaling through adapter proteins
-
Furge K.A., Zhang Y.W., Vande Woude G.F. Met receptor tyrosine kinase: enhanced signaling through adapter proteins. Oncogene 2000, 19:5582-5589.
-
(2000)
Oncogene
, vol.19
, pp. 5582-5589
-
-
Furge, K.A.1
Zhang, Y.W.2
Vande Woude, G.F.3
-
28
-
-
0037478437
-
Hypoxia promotes invasive growth by transcriptional activation of the met protooncogene
-
Pennacchietti S., Michieli P., Galluzzo M., Mazzone M., Giordano S., Comoglio P.M. Hypoxia promotes invasive growth by transcriptional activation of the met protooncogene. Cancer Cell 2003, 3:347-361.
-
(2003)
Cancer Cell
, vol.3
, pp. 347-361
-
-
Pennacchietti, S.1
Michieli, P.2
Galluzzo, M.3
Mazzone, M.4
Giordano, S.5
Comoglio, P.M.6
-
29
-
-
33745354482
-
Hypoxia enhances c-Met/HGF receptor expression and signaling by activating HIF-1alpha in human salivary gland cancer cells
-
Hara S., Nakashiro K., Klosek S.K., Ishikawa T., Shintani S., Hamakawa H. Hypoxia enhances c-Met/HGF receptor expression and signaling by activating HIF-1alpha in human salivary gland cancer cells. Oral Oncol 2006, 42:593-598.
-
(2006)
Oral Oncol
, vol.42
, pp. 593-598
-
-
Hara, S.1
Nakashiro, K.2
Klosek, S.K.3
Ishikawa, T.4
Shintani, S.5
Hamakawa, H.6
-
30
-
-
34250340883
-
Hypoxia can induce c-Met expression in glioma cells and enhance SF/HGF-induced cell migration
-
Eckerich C., Zapf S., Fillbrandt R., Loges S., Westphal M., Lamszus K. Hypoxia can induce c-Met expression in glioma cells and enhance SF/HGF-induced cell migration. Int J Cancer 2007, 121:276-283.
-
(2007)
Int J Cancer
, vol.121
, pp. 276-283
-
-
Eckerich, C.1
Zapf, S.2
Fillbrandt, R.3
Loges, S.4
Westphal, M.5
Lamszus, K.6
-
31
-
-
42049110099
-
Hypoxic regulation of metastasis via hypoxia-inducible factors
-
Gort E.H., Groot A.J., van der Wall E., van Diest P.J., Vooijs M.A. Hypoxic regulation of metastasis via hypoxia-inducible factors. Curr Mol Med 2008, 8:60-67.
-
(2008)
Curr Mol Med
, vol.8
, pp. 60-67
-
-
Gort, E.H.1
Groot, A.J.2
van der Wall, E.3
van Diest, P.J.4
Vooijs, M.A.5
-
32
-
-
40949122258
-
A microRNA component of the hypoxic response
-
Kulshreshtha R., Davuluri R.V., Calin G.A., Ivan M. A microRNA component of the hypoxic response. Cell Death Differ 2008, 15:667-671.
-
(2008)
Cell Death Differ
, vol.15
, pp. 667-671
-
-
Kulshreshtha, R.1
Davuluri, R.V.2
Calin, G.A.3
Ivan, M.4
-
33
-
-
36849077497
-
Regulation of microRNA expression: the hypoxic component
-
Kulshreshtha R., Ferracin M., Negrini M., Calin G.A., Davuluri R.V., Ivan M. Regulation of microRNA expression: the hypoxic component. Cell Cycle 2007, 6:1426-1431.
-
(2007)
Cell Cycle
, vol.6
, pp. 1426-1431
-
-
Kulshreshtha, R.1
Ferracin, M.2
Negrini, M.3
Calin, G.A.4
Davuluri, R.V.5
Ivan, M.6
-
35
-
-
40949137731
-
Hsa-miR-210 Is induced by hypoxia and is an independent prognostic factor in breast cancer
-
Camps C., Buffa F.M., Colella S., et al. hsa-miR-210 Is induced by hypoxia and is an independent prognostic factor in breast cancer. Clin Cancer Res 2008, 14:1340-1348.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 1340-1348
-
-
Camps, C.1
Buffa, F.M.2
Colella, S.3
-
36
-
-
54049105673
-
Hypoxia response and microRNAs: no longer two separate worlds
-
Ivan M., Harris A.L., Martelli F., Kulshreshtha R. Hypoxia response and microRNAs: no longer two separate worlds. J Cell Mol Med 2008, 12:1426-1431.
-
(2008)
J Cell Mol Med
, vol.12
, pp. 1426-1431
-
-
Ivan, M.1
Harris, A.L.2
Martelli, F.3
Kulshreshtha, R.4
-
37
-
-
42549092314
-
MiR-210 links hypoxia with cell cycle regulation and is deleted in human epithelial ovarian cancer
-
Giannakakis A., Sandaltzopoulos R., Greshock J., et al. miR-210 links hypoxia with cell cycle regulation and is deleted in human epithelial ovarian cancer. Cancer Biol Ther 2008, 7:255-264.
-
(2008)
Cancer Biol Ther
, vol.7
, pp. 255-264
-
-
Giannakakis, A.1
Sandaltzopoulos, R.2
Greshock, J.3
-
38
-
-
33846879810
-
The von Hippel-Lindau tumor suppressor protein and clear cell renal carcinoma
-
Kaelin W.G. The von Hippel-Lindau tumor suppressor protein and clear cell renal carcinoma. Clin Cancer Res 2007, 13:680s-684s.
-
(2007)
Clin Cancer Res
, vol.13
-
-
Kaelin, W.G.1
-
39
-
-
0035012605
-
HER2 (neu) signaling increases the rate of hypoxia-inducible factor 1alpha (HIF-1alpha) synthesis: novel mechanism for HIF-1-mediated vascular endothelial growth factor expression
-
Laughner E., Taghavi P., Chiles K., Mahon P.C., Semenza G.L. HER2 (neu) signaling increases the rate of hypoxia-inducible factor 1alpha (HIF-1alpha) synthesis: novel mechanism for HIF-1-mediated vascular endothelial growth factor expression. Mol Cell Biol 2001, 21:3995-4004.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 3995-4004
-
-
Laughner, E.1
Taghavi, P.2
Chiles, K.3
Mahon, P.C.4
Semenza, G.L.5
-
40
-
-
0034050050
-
Loss of PTEN facilitates HIF-1-mediated gene expression
-
Zundel W., Schindler C., Haas-Kogan D., et al. Loss of PTEN facilitates HIF-1-mediated gene expression. Genes Dev 2000, 14:391-396.
-
(2000)
Genes Dev
, vol.14
, pp. 391-396
-
-
Zundel, W.1
Schindler, C.2
Haas-Kogan, D.3
-
41
-
-
33749817738
-
Hypoxia-inducible factor-1alpha expression requires PI 3-kinase activity and correlates with Akt1 phosphorylation in invasive breast carcinomas
-
Gort E.H., Groot A.J., Derks van de Ven T.L., et al. Hypoxia-inducible factor-1alpha expression requires PI 3-kinase activity and correlates with Akt1 phosphorylation in invasive breast carcinomas. Oncogene 2006, 25:6123-6127.
-
(2006)
Oncogene
, vol.25
, pp. 6123-6127
-
-
Gort, E.H.1
Groot, A.J.2
Derks van de Ven, T.L.3
-
42
-
-
17144372970
-
A hypoxia-independent hypoxia-inducible factor-1 activation pathway induced by phosphatidylinositol-3 kinase/Akt in HER2 overexpressing cells
-
Li Y.M., Zhou B.P., Deng J., Pan Y., Hay N., Hung M.C. A hypoxia-independent hypoxia-inducible factor-1 activation pathway induced by phosphatidylinositol-3 kinase/Akt in HER2 overexpressing cells. Cancer Res 2005, 65:3257-3263.
-
(2005)
Cancer Res
, vol.65
, pp. 3257-3263
-
-
Li, Y.M.1
Zhou, B.P.2
Deng, J.3
Pan, Y.4
Hay, N.5
Hung, M.C.6
-
43
-
-
0034925041
-
Phosphatidylinositol 3-kinase signaling controls levels of hypoxia-inducible factor 1
-
Jiang B.H., Jiang G., Zheng J.Z., Lu Z., Hunter T., Vogt P.K. Phosphatidylinositol 3-kinase signaling controls levels of hypoxia-inducible factor 1. Cell Growth Differ 2001, 12:363-369.
-
(2001)
Cell Growth Differ
, vol.12
, pp. 363-369
-
-
Jiang, B.H.1
Jiang, G.2
Zheng, J.Z.3
Lu, Z.4
Hunter, T.5
Vogt, P.K.6
-
44
-
-
0037064010
-
Insulin-like growth factor 1 induces hypoxia-inducible factor 1-mediated vascular endothelial growth factor expression, which is dependent on MAP kinase and phosphatidylinositol 3-kinase signaling in colon cancer cells
-
Fukuda R., Hirota K., Fan F., Jung Y.D., Ellis L.M., Semenza G.L. Insulin-like growth factor 1 induces hypoxia-inducible factor 1-mediated vascular endothelial growth factor expression, which is dependent on MAP kinase and phosphatidylinositol 3-kinase signaling in colon cancer cells. J Biol Chem 2002, 277:38205-38211.
-
(2002)
J Biol Chem
, vol.277
, pp. 38205-38211
-
-
Fukuda, R.1
Hirota, K.2
Fan, F.3
Jung, Y.D.4
Ellis, L.M.5
Semenza, G.L.6
-
45
-
-
0033954247
-
Regulation of tumor angiogenesis by p53-induced degradation of hypoxia-inducible factor 1alpha
-
Ravi R., Mookerjee B., Bhujwalla Z.M., et al. Regulation of tumor angiogenesis by p53-induced degradation of hypoxia-inducible factor 1alpha. Genes Dev 2000, 14:34-44.
-
(2000)
Genes Dev
, vol.14
, pp. 34-44
-
-
Ravi, R.1
Mookerjee, B.2
Bhujwalla, Z.M.3
-
46
-
-
28744451386
-
Mutation analysis of the HIF-1alpha oxygen-dependent degradation domain in invasive breast cancer
-
Vleugel M.M., Greijer A.E., van der Wall E., van Diest P.J. Mutation analysis of the HIF-1alpha oxygen-dependent degradation domain in invasive breast cancer. Cancer Genet Cytogenet 2005, 163:168-172.
-
(2005)
Cancer Genet Cytogenet
, vol.163
, pp. 168-172
-
-
Vleugel, M.M.1
Greijer, A.E.2
van der Wall, E.3
van Diest, P.J.4
-
47
-
-
21444443309
-
No amplifications of hypoxia-inducible factor-1alpha gene in invasive breast cancer: a tissue microarray study
-
Vleugel M.M., Bos R., Buerger H., et al. No amplifications of hypoxia-inducible factor-1alpha gene in invasive breast cancer: a tissue microarray study. Cell Oncol 2004, 26:347-351.
-
(2004)
Cell Oncol
, vol.26
, pp. 347-351
-
-
Vleugel, M.M.1
Bos, R.2
Buerger, H.3
-
48
-
-
17644397056
-
Identification of hypoxia-inducible factor-1alpha (HIF-1alpha) polymorphism as a mutation in prostate cancer that prevents normoxia-induced degradation
-
Fu X.S., Choi E., Bubley G.J., Balk S.P. Identification of hypoxia-inducible factor-1alpha (HIF-1alpha) polymorphism as a mutation in prostate cancer that prevents normoxia-induced degradation. Prostate 2005, 63:215-221.
-
(2005)
Prostate
, vol.63
, pp. 215-221
-
-
Fu, X.S.1
Choi, E.2
Bubley, G.J.3
Balk, S.P.4
-
49
-
-
41149154289
-
HIF-1alpha gene mutations are associated with higher microvessel density in endometrial carcinomas
-
Horrée N., Groot A.J., van Hattem W., Heintz A.P., Vooijs M.A., van Diest P.J. HIF-1alpha gene mutations are associated with higher microvessel density in endometrial carcinomas. Histopathology 2008, 52:637-639.
-
(2008)
Histopathology
, vol.52
, pp. 637-639
-
-
Horrée, N.1
Groot, A.J.2
van Hattem, W.3
Heintz, A.P.4
Vooijs, M.A.5
van Diest, P.J.6
-
51
-
-
0037100063
-
Expression of hypoxia-inducible factor-1alpha in cervical carcinomas: correlation with tumor oxygenation
-
Haugland H.K., Vukovic V., Pintilie M., et al. Expression of hypoxia-inducible factor-1alpha in cervical carcinomas: correlation with tumor oxygenation. Int J Radiat Oncol Biol Phys 2002, 53:854-861.
-
(2002)
Int J Radiat Oncol Biol Phys
, vol.53
, pp. 854-861
-
-
Haugland, H.K.1
Vukovic, V.2
Pintilie, M.3
-
52
-
-
19944429962
-
Hypoxia-inducible factor 1alpha expression as an intrinsic marker of hypoxia: correlation with tumor oxygen, pimonidazole measurements, and outcome in locally advanced carcinoma of the cervix
-
Hutchison G.J., Valentine H.R., Loncaster J.A., et al. Hypoxia-inducible factor 1alpha expression as an intrinsic marker of hypoxia: correlation with tumor oxygen, pimonidazole measurements, and outcome in locally advanced carcinoma of the cervix. Clin Cancer Res 2004, 10:8405-8412.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 8405-8412
-
-
Hutchison, G.J.1
Valentine, H.R.2
Loncaster, J.A.3
-
53
-
-
4143118037
-
Lack of correlation between expression of HIF-1alpha protein and oxygenation status in identical tissue areas of squamous cell carcinomas of the uterine cervix
-
Mayer A., Wree A., Hoeckel M., Leo C., Pilch H., Vaupel P. Lack of correlation between expression of HIF-1alpha protein and oxygenation status in identical tissue areas of squamous cell carcinomas of the uterine cervix. Cancer Res 2004, 64:5876-5881.
-
(2004)
Cancer Res
, vol.64
, pp. 5876-5881
-
-
Mayer, A.1
Wree, A.2
Hoeckel, M.3
Leo, C.4
Pilch, H.5
Vaupel, P.6
-
54
-
-
33644884451
-
Comparison between pimonidazole binding, oxygen electrode measurements, and expression of endogenous hypoxia markers in cancer of the uterine cervix
-
Jankovic B., Aquino-Parsons C., Raleigh J.A., et al. Comparison between pimonidazole binding, oxygen electrode measurements, and expression of endogenous hypoxia markers in cancer of the uterine cervix. Cytometry B Clin Cytom 2006, 70:45-55.
-
(2006)
Cytometry B Clin Cytom
, vol.70
, pp. 45-55
-
-
Jankovic, B.1
Aquino-Parsons, C.2
Raleigh, J.A.3
-
55
-
-
40549100361
-
Prognostic impact of HIF-1alpha expression in patients with definitive radiotherapy for cervical cancer
-
Dellas K., Bache M., Pigorsch S.U., et al. Prognostic impact of HIF-1alpha expression in patients with definitive radiotherapy for cervical cancer. Strahlenther Onkol 2008, 184:169-174.
-
(2008)
Strahlenther Onkol
, vol.184
, pp. 169-174
-
-
Dellas, K.1
Bache, M.2
Pigorsch, S.U.3
-
56
-
-
0345491970
-
Carbonic anhydrase IX expression, hypoxia, and prognosis in patients with uterine cervical carcinomas
-
Hedley D., Pintilie M., Woo J., et al. Carbonic anhydrase IX expression, hypoxia, and prognosis in patients with uterine cervical carcinomas. Clin Cancer Res 2003, 9:5666-5674.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 5666-5674
-
-
Hedley, D.1
Pintilie, M.2
Woo, J.3
-
57
-
-
17644425583
-
Microregional expression of glucose transporter-1 and oxygenation status: lack of correlation in locally advanced cervical cancers
-
Mayer A., Hoeckel M., Wree A., Vaupel P. Microregional expression of glucose transporter-1 and oxygenation status: lack of correlation in locally advanced cervical cancers. Clin Cancer Res 2005, 11:2768-2773.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 2768-2773
-
-
Mayer, A.1
Hoeckel, M.2
Wree, A.3
Vaupel, P.4
-
58
-
-
0035418586
-
Carbonic anhydrase (CA IX) expression, a potential new intrinsic marker of hypoxia: correlations with tumor oxygen measurements and prognosis in locally advanced carcinoma of the cervix
-
Loncaster J.A., Harris A.L., Davidson S.E., et al. Carbonic anhydrase (CA IX) expression, a potential new intrinsic marker of hypoxia: correlations with tumor oxygen measurements and prognosis in locally advanced carcinoma of the cervix. Cancer Res 2001, 61:6394-6399.
-
(2001)
Cancer Res
, vol.61
, pp. 6394-6399
-
-
Loncaster, J.A.1
Harris, A.L.2
Davidson, S.E.3
-
59
-
-
0034900493
-
Glucose transporter glut-1 expression correlates with tumor hypoxia and predicts metastasis-free survival in advanced carcinoma of the cervix
-
Airley R., Loncaster J., Davidson S., et al. Glucose transporter glut-1 expression correlates with tumor hypoxia and predicts metastasis-free survival in advanced carcinoma of the cervix. Clin Cancer Res 2001, 7:928-934.
-
(2001)
Clin Cancer Res
, vol.7
, pp. 928-934
-
-
Airley, R.1
Loncaster, J.2
Davidson, S.3
-
60
-
-
0037847453
-
Measurements of hypoxia using pimonidazole and polarographic oxygen-sensitive electrodes in human cervix carcinomas
-
Nordsmark M., Loncaster J., Aquino-Parsons C., et al. Measurements of hypoxia using pimonidazole and polarographic oxygen-sensitive electrodes in human cervix carcinomas. Radiother Oncol 2003, 67:35-44.
-
(2003)
Radiother Oncol
, vol.67
, pp. 35-44
-
-
Nordsmark, M.1
Loncaster, J.2
Aquino-Parsons, C.3
-
61
-
-
34249823960
-
Hypoxia and angiogenesis in endometrioid endometrial carcinogenesis
-
Horrée N., van Diest P.J., van der Groep P., Sie-Go D.M., Heintz A.P. Hypoxia and angiogenesis in endometrioid endometrial carcinogenesis. Cell Oncol 2007, 29:219-227.
-
(2007)
Cell Oncol
, vol.29
, pp. 219-227
-
-
Horrée, N.1
van Diest, P.J.2
van der Groep, P.3
Sie-Go, D.M.4
Heintz, A.P.5
-
63
-
-
30944462014
-
Hypoxia-inducible factor-1alpha expression in human endometrium and its regulation by prostaglandin E-series prostanoid receptor 2 (EP2)
-
Critchley H.O., Osei J., Henderson T.A., et al. Hypoxia-inducible factor-1alpha expression in human endometrium and its regulation by prostaglandin E-series prostanoid receptor 2 (EP2). Endocrinology 2006, 147:744-753.
-
(2006)
Endocrinology
, vol.147
, pp. 744-753
-
-
Critchley, H.O.1
Osei, J.2
Henderson, T.A.3
-
64
-
-
0036183269
-
Expression of hypoxia-inducible factors in human endometrium and suppression of matrix metalloproteinases under hypoxic conditions do not support a major role for hypoxia in regulating tissue breakdown at menstruation
-
Zhang J., Salamonsen L.A. Expression of hypoxia-inducible factors in human endometrium and suppression of matrix metalloproteinases under hypoxic conditions do not support a major role for hypoxia in regulating tissue breakdown at menstruation. Hum Reprod 2002, 17:265-274.
-
(2002)
Hum Reprod
, vol.17
, pp. 265-274
-
-
Zhang, J.1
Salamonsen, L.A.2
-
65
-
-
2442650576
-
Prognostic significance of erythropoietin expression in human endometrial carcinoma
-
Acs G., Xu X., Chu C., Acs P., Verma A. Prognostic significance of erythropoietin expression in human endometrial carcinoma. Cancer 2004, 100:2376-2386.
-
(2004)
Cancer
, vol.100
, pp. 2376-2386
-
-
Acs, G.1
Xu, X.2
Chu, C.3
Acs, P.4
Verma, A.5
-
66
-
-
39249084048
-
Neoangiogenesis and expression of hypoxia-inducible factor 1alpha, vascular endothelial growth factor, and glucose transporter-1 in endometrioid type endometrium adenocarcinomas
-
Ozbudak I.H., Karaveli S., Simsek T., Erdogan G., Pestereli E. Neoangiogenesis and expression of hypoxia-inducible factor 1alpha, vascular endothelial growth factor, and glucose transporter-1 in endometrioid type endometrium adenocarcinomas. Gynecol Oncol 2008, 108:603-608.
-
(2008)
Gynecol Oncol
, vol.108
, pp. 603-608
-
-
Ozbudak, I.H.1
Karaveli, S.2
Simsek, T.3
Erdogan, G.4
Pestereli, E.5
-
67
-
-
33845710706
-
Increased expression of hypoxia-inducible factor 1alpha in type I and type II endometrial carcinomas
-
Pansare V., Munkarah A.R., Schimp V., et al. Increased expression of hypoxia-inducible factor 1alpha in type I and type II endometrial carcinomas. Mod Pathol 2007, 20:35-43.
-
(2007)
Mod Pathol
, vol.20
, pp. 35-43
-
-
Pansare, V.1
Munkarah, A.R.2
Schimp, V.3
-
68
-
-
33646431196
-
The racial disparity in outcomes in endometrial cancer: could this be explained on a molecular level?
-
Schimp V.L., li-Fehmi R., Solomon L.A., et al. The racial disparity in outcomes in endometrial cancer: could this be explained on a molecular level?. Gynecol Oncol 2006, 102:440-446.
-
(2006)
Gynecol Oncol
, vol.102
, pp. 440-446
-
-
Schimp, V.L.1
li-Fehmi, R.2
Solomon, L.A.3
-
69
-
-
0033571682
-
Overexpression of hypoxia-inducible factor 1alpha in common human cancers and their metastases
-
Zhong H., De Marzo A.M., Laughner E., et al. Overexpression of hypoxia-inducible factor 1alpha in common human cancers and their metastases. Cancer Res 1999, 59:5830-5835.
-
(1999)
Cancer Res
, vol.59
, pp. 5830-5835
-
-
Zhong, H.1
De Marzo, A.M.2
Laughner, E.3
-
70
-
-
0030781053
-
PTEN/MMAC1 mutations in endometrial cancers
-
Risinger J.I., Hayes A.K., Berchuck A., Barrett J.C. PTEN/MMAC1 mutations in endometrial cancers. Cancer Res 1997, 57:4736-4738.
-
(1997)
Cancer Res
, vol.57
, pp. 4736-4738
-
-
Risinger, J.I.1
Hayes, A.K.2
Berchuck, A.3
Barrett, J.C.4
-
71
-
-
84984777123
-
PTEN1 is frequently mutated in primary endometrial carcinomas
-
Kong D., Suzuki A., Zou T.T., et al. PTEN1 is frequently mutated in primary endometrial carcinomas. Nat Genet 1997, 17:143-144.
-
(1997)
Nat Genet
, vol.17
, pp. 143-144
-
-
Kong, D.1
Suzuki, A.2
Zou, T.T.3
-
72
-
-
0033774009
-
Absence of PTEN repeat tract mutation in endometrial cancers with microsatellite instability
-
Cohn D.E., Basil J.B., Venegoni A.R., et al. Absence of PTEN repeat tract mutation in endometrial cancers with microsatellite instability. Gynecol Oncol 2000, 79:101-106.
-
(2000)
Gynecol Oncol
, vol.79
, pp. 101-106
-
-
Cohn, D.E.1
Basil, J.B.2
Venegoni, A.R.3
-
73
-
-
34447302617
-
Hypoxia contributes to development of recurrent endometrial carcinoma
-
Pijnenborg J.M., Wijnakker M., Hagelstein J., Delvoux B., Groothuis P.G. Hypoxia contributes to development of recurrent endometrial carcinoma. Int J Gynecol Cancer 2007, 17:897-904.
-
(2007)
Int J Gynecol Cancer
, vol.17
, pp. 897-904
-
-
Pijnenborg, J.M.1
Wijnakker, M.2
Hagelstein, J.3
Delvoux, B.4
Groothuis, P.G.5
-
74
-
-
67349198732
-
Association of hypoxia-inducible factor-1 expression with histology in epithelial ovarian tumors: a quantitative analysis of HIF-1
-
Miyazawa M., Yasuda M., Fujita M., et al. Association of hypoxia-inducible factor-1 expression with histology in epithelial ovarian tumors: a quantitative analysis of HIF-1. Arch Gynecol Obstet 2009, 279:789-796.
-
(2009)
Arch Gynecol Obstet
, vol.279
, pp. 789-796
-
-
Miyazawa, M.1
Yasuda, M.2
Fujita, M.3
-
75
-
-
0034282518
-
Overexpression of hypoxia-inducible factor 1alpha is a marker for an unfavorable prognosis in early-stage invasive cervical cancer
-
Birner P., Schindl M., Obermair A., Plank C., Breitenecker G., Oberhuber G. Overexpression of hypoxia-inducible factor 1alpha is a marker for an unfavorable prognosis in early-stage invasive cervical cancer. Cancer Res 2000, 60:4693-4696.
-
(2000)
Cancer Res
, vol.60
, pp. 4693-4696
-
-
Birner, P.1
Schindl, M.2
Obermair, A.3
Plank, C.4
Breitenecker, G.5
Oberhuber, G.6
-
76
-
-
0029029938
-
P53 inactivation by HPV16 E6 results in increased mutagenesis in human cells
-
Havre P.A., Yuan J., Hedrick L., Cho K.R., Glazer P.M. p53 inactivation by HPV16 E6 results in increased mutagenesis in human cells. Cancer Res 1995, 55:4420-4424.
-
(1995)
Cancer Res
, vol.55
, pp. 4420-4424
-
-
Havre, P.A.1
Yuan, J.2
Hedrick, L.3
Cho, K.R.4
Glazer, P.M.5
-
77
-
-
34249010891
-
Overexpression of human papillomavirus type 16 oncoproteins enhances hypoxia-inducible factor 1 alpha protein accumulation and vascular endothelial growth factor expression in human cervical carcinoma cells
-
Tang X., Zhang Q., Nishitani J., Brown J., Shi S., Le A.D. Overexpression of human papillomavirus type 16 oncoproteins enhances hypoxia-inducible factor 1 alpha protein accumulation and vascular endothelial growth factor expression in human cervical carcinoma cells. Clin Cancer Res 2007, 13:2568-2576.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 2568-2576
-
-
Tang, X.1
Zhang, Q.2
Nishitani, J.3
Brown, J.4
Shi, S.5
Le, A.D.6
-
78
-
-
0028199891
-
Inhibition of p53 DNA binding by human papillomavirus E6 proteins
-
Lechner M.S., Laimins L.A. Inhibition of p53 DNA binding by human papillomavirus E6 proteins. J Virol 1994, 68:4262-4273.
-
(1994)
J Virol
, vol.68
, pp. 4262-4273
-
-
Lechner, M.S.1
Laimins, L.A.2
-
79
-
-
0037500967
-
Overexpression of hypoxia-inducible factor 1alpha indicates diminished response to radiotherapy and unfavorable prognosis in patients receiving radical radiotherapy for cervical cancer
-
Bachtiary B., Schindl M., Potter R., et al. Overexpression of hypoxia-inducible factor 1alpha indicates diminished response to radiotherapy and unfavorable prognosis in patients receiving radical radiotherapy for cervical cancer. Clin Cancer Res 2003, 9:2234-2240.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 2234-2240
-
-
Bachtiary, B.1
Schindl, M.2
Potter, R.3
-
80
-
-
0032568448
-
Stabilization of wild-type p53 by hypoxia-inducible factor 1alpha
-
An W.G., Kanekal M., Simon M.C., Maltepe E., Blagosklonny M.V., Neckers L.M. Stabilization of wild-type p53 by hypoxia-inducible factor 1alpha. Nature 1998, 392:405-408.
-
(1998)
Nature
, vol.392
, pp. 405-408
-
-
An, W.G.1
Kanekal, M.2
Simon, M.C.3
Maltepe, E.4
Blagosklonny, M.V.5
Neckers, L.M.6
-
81
-
-
0030025773
-
Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours
-
Graeber T.G., Osmanian C., Jacks T., et al. Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours. Nature 1996, 379:88-91.
-
(1996)
Nature
, vol.379
, pp. 88-91
-
-
Graeber, T.G.1
Osmanian, C.2
Jacks, T.3
-
82
-
-
0029775242
-
Association between tumor hypoxia and malignant progression in advanced cancer of the uterine cervix
-
Hoeckel M., Schlenger K., Aral B., Mitze M., Schaffer U., Vaupel P. Association between tumor hypoxia and malignant progression in advanced cancer of the uterine cervix. Cancer Res 1996, 56:4509-4515.
-
(1996)
Cancer Res
, vol.56
, pp. 4509-4515
-
-
Hoeckel, M.1
Schlenger, K.2
Aral, B.3
Mitze, M.4
Schaffer, U.5
Vaupel, P.6
-
83
-
-
0036467638
-
Tumor hypoxia has independent predictor impact only in patients with node-negative cervix cancer
-
Fyles A., Milosevic M., Hedley D., et al. Tumor hypoxia has independent predictor impact only in patients with node-negative cervix cancer. J Clin Oncol 2002, 20:680-687.
-
(2002)
J Clin Oncol
, vol.20
, pp. 680-687
-
-
Fyles, A.1
Milosevic, M.2
Hedley, D.3
-
85
-
-
0033922706
-
Hypoxia-induced treatment failure in advanced squamous cell carcinoma of the uterine cervix is primarily due to hypoxia-induced radiation resistance rather than hypoxia-induced metastasis
-
Rofstad E.K., Sundfor K., Lyng H., Trope C.G. Hypoxia-induced treatment failure in advanced squamous cell carcinoma of the uterine cervix is primarily due to hypoxia-induced radiation resistance rather than hypoxia-induced metastasis. Br J Cancer 2000, 83:354-359.
-
(2000)
Br J Cancer
, vol.83
, pp. 354-359
-
-
Rofstad, E.K.1
Sundfor, K.2
Lyng, H.3
Trope, C.G.4
-
86
-
-
0038300418
-
Significant correlation of hypoxia-inducible factor-1alpha with treatment outcome in cervical cancer treated with radical radiotherapy
-
Burri P., Djonov V., Aebersold D.M., et al. Significant correlation of hypoxia-inducible factor-1alpha with treatment outcome in cervical cancer treated with radical radiotherapy. Int J Radiat Oncol Biol Phys 2003, 56:494-501.
-
(2003)
Int J Radiat Oncol Biol Phys
, vol.56
, pp. 494-501
-
-
Burri, P.1
Djonov, V.2
Aebersold, D.M.3
-
87
-
-
4544276339
-
Expression of hypoxic-inducible factor 1alpha predicts metastasis-free survival after radiation therapy alone in stage IIIB cervical squamous cell carcinoma
-
Ishikawa H., Sakurai H., Hasegawa M., et al. Expression of hypoxic-inducible factor 1alpha predicts metastasis-free survival after radiation therapy alone in stage IIIB cervical squamous cell carcinoma. Int J Radiat Oncol Biol Phys 2004, 60:513-521.
-
(2004)
Int J Radiat Oncol Biol Phys
, vol.60
, pp. 513-521
-
-
Ishikawa, H.1
Sakurai, H.2
Hasegawa, M.3
-
88
-
-
39549085348
-
Elevated CAIX expression is associated with an increased risk of distant failure in early-stage cervical cancer
-
Kirkpatrick J.P., Rabbani Z.N., Bentley R.C., et al. Elevated CAIX expression is associated with an increased risk of distant failure in early-stage cervical cancer. Biomark Insights 2008, 3:45-55.
-
(2008)
Biomark Insights
, vol.3
, pp. 45-55
-
-
Kirkpatrick, J.P.1
Rabbani, Z.N.2
Bentley, R.C.3
-
89
-
-
34547838192
-
Expression of hypoxia-inducible factor 1alpha, hypoxia-inducible factor 2alpha, and von Hippel-Lindau protein in epithelial ovarian neoplasms and allelic loss of von Hippel-Lindau gene: nuclear expression of hypoxia-inducible factor 1alpha is an independent prognostic factor in ovarian carcinoma
-
Osada R., Horiuchi A., Kikuchi N., et al. Expression of hypoxia-inducible factor 1alpha, hypoxia-inducible factor 2alpha, and von Hippel-Lindau protein in epithelial ovarian neoplasms and allelic loss of von Hippel-Lindau gene: nuclear expression of hypoxia-inducible factor 1alpha is an independent prognostic factor in ovarian carcinoma. Hum Pathol 2007, 38:1310-1320.
-
(2007)
Hum Pathol
, vol.38
, pp. 1310-1320
-
-
Osada, R.1
Horiuchi, A.2
Kikuchi, N.3
-
90
-
-
34447619912
-
Over-expression of hypoxia-inducible factor 1 alpha in ovarian clear cell carcinoma
-
Lee S., Garner E.I., Welch W.R., Berkowitz R.S., Mok S.C. Over-expression of hypoxia-inducible factor 1 alpha in ovarian clear cell carcinoma. Gynecol Oncol 2007, 106:311-317.
-
(2007)
Gynecol Oncol
, vol.106
, pp. 311-317
-
-
Lee, S.1
Garner, E.I.2
Welch, W.R.3
Berkowitz, R.S.4
Mok, S.C.5
-
91
-
-
1642341137
-
VEGF and HIF-1alpha expression are increased in advanced stages of epithelial ovarian cancer
-
Wong C., Wellman T.L., Lounsbury K.M. VEGF and HIF-1alpha expression are increased in advanced stages of epithelial ovarian cancer. Gynecol Oncol 2003, 91:513-517.
-
(2003)
Gynecol Oncol
, vol.91
, pp. 513-517
-
-
Wong, C.1
Wellman, T.L.2
Lounsbury, K.M.3
-
92
-
-
42649141679
-
Hypoxic status in ovarian serous and mucinous tumors: relationship between histological characteristics and HIF-1alpha/GLUT-1 expression
-
Iida T., Yasuda M., Miyazawa M., et al. Hypoxic status in ovarian serous and mucinous tumors: relationship between histological characteristics and HIF-1alpha/GLUT-1 expression. Arch Gynecol Obstet 2008, 277:539-546.
-
(2008)
Arch Gynecol Obstet
, vol.277
, pp. 539-546
-
-
Iida, T.1
Yasuda, M.2
Miyazawa, M.3
-
93
-
-
0034896068
-
Expression of hypoxia-inducible factor 1alpha in epithelial ovarian tumors: its impact on prognosis and on response to chemotherapy
-
Birner P., Schindl M., Obermair A., Breitenecker G., Oberhuber G. Expression of hypoxia-inducible factor 1alpha in epithelial ovarian tumors: its impact on prognosis and on response to chemotherapy. Clin Cancer Res 2001, 7:1661-1668.
-
(2001)
Clin Cancer Res
, vol.7
, pp. 1661-1668
-
-
Birner, P.1
Schindl, M.2
Obermair, A.3
Breitenecker, G.4
Oberhuber, G.5
-
94
-
-
43449132370
-
Expression of hypoxia-inducible factor 1alpha gene affects the outcome in patients with ovarian cancer
-
Shimogai R., Kigawa J., Itamochi H., et al. Expression of hypoxia-inducible factor 1alpha gene affects the outcome in patients with ovarian cancer. Int J Gynecol Cancer 2008, 18:499-505.
-
(2008)
Int J Gynecol Cancer
, vol.18
, pp. 499-505
-
-
Shimogai, R.1
Kigawa, J.2
Itamochi, H.3
-
95
-
-
0037169870
-
Hypoxia-inducible factor 1 alpha (HIF-1 alpha) gene expression in human ovarian carcinoma
-
Nakayama K., Kanzaki A., Hata K., et al. Hypoxia-inducible factor 1 alpha (HIF-1 alpha) gene expression in human ovarian carcinoma. Cancer Lett 2002, 176:215-223.
-
(2002)
Cancer Lett
, vol.176
, pp. 215-223
-
-
Nakayama, K.1
Kanzaki, A.2
Hata, K.3
-
96
-
-
0031038420
-
Hypoxia-inducible factor-1 alpha is regulated at the post-mRNA level
-
Wenger R.H., Kvietikova I., Rolfs A., Gassmann M., Marti H.H. Hypoxia-inducible factor-1 alpha is regulated at the post-mRNA level. Kidney Int 1997, 51:560-563.
-
(1997)
Kidney Int
, vol.51
, pp. 560-563
-
-
Wenger, R.H.1
Kvietikova, I.2
Rolfs, A.3
Gassmann, M.4
Marti, H.H.5
-
97
-
-
0029802958
-
Cyclophosphamide and cisplatin versus paclitaxel and cisplatin: a phase III randomized trial in patients with suboptimal stage III/IV ovarian cancer (from the Gynecologic Oncology Group)
-
McGuire W.P., Hoskins W.J., Brady M.F., et al. Cyclophosphamide and cisplatin versus paclitaxel and cisplatin: a phase III randomized trial in patients with suboptimal stage III/IV ovarian cancer (from the Gynecologic Oncology Group). Semin Oncol 1996, 23:40-47.
-
(1996)
Semin Oncol
, vol.23
, pp. 40-47
-
-
McGuire, W.P.1
Hoskins, W.J.2
Brady, M.F.3
-
98
-
-
17744372884
-
Docetaxel-carboplatin as first line chemotherapy for epithelial ovarian cancer
-
Vasey P.A., Atkinson R., Coleman R., et al. Docetaxel-carboplatin as first line chemotherapy for epithelial ovarian cancer. Br J Cancer 2001, 84:170-178.
-
(2001)
Br J Cancer
, vol.84
, pp. 170-178
-
-
Vasey, P.A.1
Atkinson, R.2
Coleman, R.3
-
99
-
-
34247155290
-
Hypoxia inducible factor 1-alpha expression as a factor predictive of efficacy of taxane/platinum chemotherapy in advanced primary epithelial ovarian cancer
-
Nakai H., Watanabe Y., Ueda H., Hoshiai H. Hypoxia inducible factor 1-alpha expression as a factor predictive of efficacy of taxane/platinum chemotherapy in advanced primary epithelial ovarian cancer. Cancer Lett 2007, 251:164-167.
-
(2007)
Cancer Lett
, vol.251
, pp. 164-167
-
-
Nakai, H.1
Watanabe, Y.2
Ueda, H.3
Hoshiai, H.4
-
100
-
-
0035446816
-
GLUT-1 expression in ovarian carcinoma: association with survival and response to chemotherapy
-
Cantuaria G., Fagotti A., Ferrandina G., et al. GLUT-1 expression in ovarian carcinoma: association with survival and response to chemotherapy. Cancer 2001, 92:1144-1150.
-
(2001)
Cancer
, vol.92
, pp. 1144-1150
-
-
Cantuaria, G.1
Fagotti, A.2
Ferrandina, G.3
-
101
-
-
0342857011
-
Tumor hypoxia in pelvic recurrences of cervical cancer
-
Hoeckel M., Schlenger K., Hoeckel S., Aral B., Schaffer U., Vaupel P. Tumor hypoxia in pelvic recurrences of cervical cancer. Int J Cancer 1998, 79:365-369.
-
(1998)
Int J Cancer
, vol.79
, pp. 365-369
-
-
Hoeckel, M.1
Schlenger, K.2
Hoeckel, S.3
Aral, B.4
Schaffer, U.5
Vaupel, P.6
-
102
-
-
33645970387
-
Oxygenation status of primary and recurrent squamous cell carcinomas of the vulva
-
Vaupel P., Mayer A., Hoeckel M. Oxygenation status of primary and recurrent squamous cell carcinomas of the vulva. Eur J Gynaecol Oncol 2006, 27:142-146.
-
(2006)
Eur J Gynaecol Oncol
, vol.27
, pp. 142-146
-
-
Vaupel, P.1
Mayer, A.2
Hoeckel, M.3
-
103
-
-
14644437020
-
Intratumoral oxygenation of invasive squamous cell carcimoma of the vulva is not correlated with regional lymph node metastasis
-
Stone J.E., Parker R., Gilks C.B., Stanbridge E.J., Liao S.Y., Aquino-Parsons C. Intratumoral oxygenation of invasive squamous cell carcimoma of the vulva is not correlated with regional lymph node metastasis. Eur J Gynaecol Oncol 2005, 26:31-35.
-
(2005)
Eur J Gynaecol Oncol
, vol.26
, pp. 31-35
-
-
Stone, J.E.1
Parker, R.2
Gilks, C.B.3
Stanbridge, E.J.4
Liao, S.Y.5
Aquino-Parsons, C.6
-
104
-
-
33845774278
-
The homozygous P582S mutation in the oxygen-dependent degradation domain of HIF-1 alpha is associated with increased risk for prostate cancer
-
Orr-Urtreger A., Bar-Shira A., Matzkin H., Mabjeesh N.J. The homozygous P582S mutation in the oxygen-dependent degradation domain of HIF-1 alpha is associated with increased risk for prostate cancer. Prostate 2007, 67:8-13.
-
(2007)
Prostate
, vol.67
, pp. 8-13
-
-
Orr-Urtreger, A.1
Bar-Shira, A.2
Matzkin, H.3
Mabjeesh, N.J.4
-
105
-
-
33646420620
-
Polymorphism in the hypoxia-inducible factor 1alpha gene may confer susceptibility to androgen-independent prostate cancer
-
Chau C.H., Permenter M.G., Steinberg S.M., et al. Polymorphism in the hypoxia-inducible factor 1alpha gene may confer susceptibility to androgen-independent prostate cancer. Cancer Biol Ther 2005, 4:1222-1225.
-
(2005)
Cancer Biol Ther
, vol.4
, pp. 1222-1225
-
-
Chau, C.H.1
Permenter, M.G.2
Steinberg, S.M.3
-
106
-
-
16544383367
-
Single nucleotide polymorphism in the hypoxia-inducible factor-1alpha gene in colorectal carcinoma
-
Kuwai T., Kitadai Y., Tanaka S., et al. Single nucleotide polymorphism in the hypoxia-inducible factor-1alpha gene in colorectal carcinoma. Oncol Rep 2004, 12:1033-1037.
-
(2004)
Oncol Rep
, vol.12
, pp. 1033-1037
-
-
Kuwai, T.1
Kitadai, Y.2
Tanaka, S.3
-
107
-
-
33750489434
-
Association between ulcerative growth and hypoxia inducible factor-1alpha polymorphisms in colorectal cancer patients
-
Fransen K., Fenech M., Fredrikson M., Dabrosin C., Soderkvist P. Association between ulcerative growth and hypoxia inducible factor-1alpha polymorphisms in colorectal cancer patients. Mol Carcinog 2006, 45:833-840.
-
(2006)
Mol Carcinog
, vol.45
, pp. 833-840
-
-
Fransen, K.1
Fenech, M.2
Fredrikson, M.3
Dabrosin, C.4
Soderkvist, P.5
-
108
-
-
0242559086
-
Hypoxia-inducible factor-1alpha polymorphisms associated with enhanced transactivation capacity, implying clinical significance
-
Tanimoto K., Yoshiga K., Eguchi H., et al. Hypoxia-inducible factor-1alpha polymorphisms associated with enhanced transactivation capacity, implying clinical significance. Carcinogenesis 2003, 24:1779-1783.
-
(2003)
Carcinogenesis
, vol.24
, pp. 1779-1783
-
-
Tanimoto, K.1
Yoshiga, K.2
Eguchi, H.3
-
109
-
-
33644825840
-
Common single nucleotide polymorphism of hypoxia-inducible factor-1alpha and its impact on the clinicopathological features of esophageal squamous cell carcinoma
-
Ling T.S., Shi R.H., Zhang G.X., Zhu H., Yu L.Z., Ding X.F. Common single nucleotide polymorphism of hypoxia-inducible factor-1alpha and its impact on the clinicopathological features of esophageal squamous cell carcinoma. Chin J Dig Dis 2005, 6:155-158.
-
(2005)
Chin J Dig Dis
, vol.6
, pp. 155-158
-
-
Ling, T.S.1
Shi, R.H.2
Zhang, G.X.3
Zhu, H.4
Yu, L.Z.5
Ding, X.F.6
-
110
-
-
34247618223
-
An investigation of relationships between hypoxia-inducible factor-1 alpha gene polymorphisms and ovarian, cervical and endometrial cancers
-
Konac E., Onen H.I., Metindir J., Alp E., Biri A.A., Ekmekci A. An investigation of relationships between hypoxia-inducible factor-1 alpha gene polymorphisms and ovarian, cervical and endometrial cancers. Cancer Detect Prev 2007, 31:102-109.
-
(2007)
Cancer Detect Prev
, vol.31
, pp. 102-109
-
-
Konac, E.1
Onen, H.I.2
Metindir, J.3
Alp, E.4
Biri, A.A.5
Ekmekci, A.6
-
111
-
-
0142166332
-
Targeting HIF-1 for cancer therapy
-
Semenza G.L. Targeting HIF-1 for cancer therapy. Nat Rev Cancer 2003, 3:721-732.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 721-732
-
-
Semenza, G.L.1
-
113
-
-
3843078830
-
Targeting topoisomerase I to inhibit hypoxia inducible factor 1
-
Rapisarda A., Shoemaker R.H., Melillo G. Targeting topoisomerase I to inhibit hypoxia inducible factor 1. Cell Cycle 2004, 3:172-175.
-
(2004)
Cell Cycle
, vol.3
, pp. 172-175
-
-
Rapisarda, A.1
Shoemaker, R.H.2
Melillo, G.3
-
114
-
-
35348954836
-
UVC inhibits HIF-1alpha protein translation by a DNA damage- and topoisomerase I-independent pathway
-
Rapisarda A., Melillo G. UVC inhibits HIF-1alpha protein translation by a DNA damage- and topoisomerase I-independent pathway. Oncogene 2007, 26:6875-6884.
-
(2007)
Oncogene
, vol.26
, pp. 6875-6884
-
-
Rapisarda, A.1
Melillo, G.2
-
115
-
-
35948938874
-
Topotecan in cervical cancer
-
Ackermann S., Beckmann M.W., Thiel F., Bogenrieder T. Topotecan in cervical cancer. Int J Gynecol Cancer 2007, 17:1215-1223.
-
(2007)
Int J Gynecol Cancer
, vol.17
, pp. 1215-1223
-
-
Ackermann, S.1
Beckmann, M.W.2
Thiel, F.3
Bogenrieder, T.4
-
116
-
-
34248571510
-
A phase I study of paclitaxel, topotecan, cisplatin and Filgrastim in patients with newly diagnosed advanced ovarian epithelial malignancies: a Gynecologic Oncology Group study
-
Armstrong D.K., Bookman M.A., McGuire W., Bristow R.E., Schilder J.M. A phase I study of paclitaxel, topotecan, cisplatin and Filgrastim in patients with newly diagnosed advanced ovarian epithelial malignancies: a Gynecologic Oncology Group study. Gynecol Oncol 2007, 105:667-671.
-
(2007)
Gynecol Oncol
, vol.105
, pp. 667-671
-
-
Armstrong, D.K.1
Bookman, M.A.2
McGuire, W.3
Bristow, R.E.4
Schilder, J.M.5
-
117
-
-
4444369682
-
Antitumor activity and pharmacodynamic properties of PX-478, an inhibitor of hypoxia-inducible factor-1alpha
-
Welsh S., Williams R., Kirkpatrick L., Paine-Murrieta G., Powis G. Antitumor activity and pharmacodynamic properties of PX-478, an inhibitor of hypoxia-inducible factor-1alpha. Mol Cancer Ther 2004, 3:233-244.
-
(2004)
Mol Cancer Ther
, vol.3
, pp. 233-244
-
-
Welsh, S.1
Williams, R.2
Kirkpatrick, L.3
Paine-Murrieta, G.4
Powis, G.5
-
118
-
-
33748152298
-
Oncological implications of hypoxia inducible factor-1alpha (HIF-1alpha) expression
-
O'Donnell J.L., Joyce M.R., Shannon A.M., Harmey J., Geraghty J., Bouchier-Hayes D. Oncological implications of hypoxia inducible factor-1alpha (HIF-1alpha) expression. Cancer Treat Rev 2006, 32:407-416.
-
(2006)
Cancer Treat Rev
, vol.32
, pp. 407-416
-
-
O'Donnell, J.L.1
Joyce, M.R.2
Shannon, A.M.3
Harmey, J.4
Geraghty, J.5
Bouchier-Hayes, D.6
-
119
-
-
0032749463
-
Hypoxia-induced activation of HIF-1: role of HIF-1alpha-Hsp90 interaction
-
Minet E., Mottet D., Michel G., et al. Hypoxia-induced activation of HIF-1: role of HIF-1alpha-Hsp90 interaction. FEBS Lett 1999, 460:251-256.
-
(1999)
FEBS Lett
, vol.460
, pp. 251-256
-
-
Minet, E.1
Mottet, D.2
Michel, G.3
-
120
-
-
33645376457
-
Hypoxia-inducible factor 1alpha (HIF-1alpha) correlated with tumor growth and apoptosis in ovarian cancer
-
Jiang H., Feng Y. Hypoxia-inducible factor 1alpha (HIF-1alpha) correlated with tumor growth and apoptosis in ovarian cancer. Int J Gynecol Cancer 2006, 16(Suppl. 1):405-412.
-
(2006)
Int J Gynecol Cancer
, vol.16
, Issue.SUPPL. 1
, pp. 405-412
-
-
Jiang, H.1
Feng, Y.2
-
121
-
-
0035863303
-
Phase I trial of concurrent tirapazamine, cisplatin, and radiotherapy in patients with advanced head and neck cancer
-
Rischin D., Peters L., Hicks R., et al. Phase I trial of concurrent tirapazamine, cisplatin, and radiotherapy in patients with advanced head and neck cancer. J Clin Oncol 2001, 19:535-542.
-
(2001)
J Clin Oncol
, vol.19
, pp. 535-542
-
-
Rischin, D.1
Peters, L.2
Hicks, R.3
-
122
-
-
34249981734
-
Cisplatin and doxorubicin repress vascular endothelial growth factor expression and differentially down-regulate Hypoxia-inducible Factor I activity in human ovarian cancer cells
-
Duyndam M.C., van Berkel M.P., Dorsman J.C., Rockx D.A., Pinedo H.M., Boven E. Cisplatin and doxorubicin repress vascular endothelial growth factor expression and differentially down-regulate Hypoxia-inducible Factor I activity in human ovarian cancer cells. Biochem Pharmacol 2007, 74:191-201.
-
(2007)
Biochem Pharmacol
, vol.74
, pp. 191-201
-
-
Duyndam, M.C.1
van Berkel, M.P.2
Dorsman, J.C.3
Rockx, D.A.4
Pinedo, H.M.5
Boven, E.6
-
123
-
-
0036682284
-
Identification of small molecule inhibitors of hypoxia-inducible factor 1 transcriptional activation pathway
-
Rapisarda A., Uranchimeg B., Scudiero D.A., et al. Identification of small molecule inhibitors of hypoxia-inducible factor 1 transcriptional activation pathway. Cancer Res 2002, 62:4316-4324.
-
(2002)
Cancer Res
, vol.62
, pp. 4316-4324
-
-
Rapisarda, A.1
Uranchimeg, B.2
Scudiero, D.A.3
-
124
-
-
0036569704
-
Geldanamycin induces degradation of hypoxia-inducible factor 1alpha protein via the proteosome pathway in prostate cancer cells
-
Mabjeesh N.J., Post D.E., Willard M.T., et al. Geldanamycin induces degradation of hypoxia-inducible factor 1alpha protein via the proteosome pathway in prostate cancer cells. Cancer Res 2002, 62:2478-2482.
-
(2002)
Cancer Res
, vol.62
, pp. 2478-2482
-
-
Mabjeesh, N.J.1
Post, D.E.2
Willard, M.T.3
-
125
-
-
38349092288
-
Molecular mechanisms for the activity of PX-478, an antitumor inhibitor of the hypoxia-inducible factor-1alpha
-
Koh M.Y., Spivak-Kroizman T., Venturini S., et al. Molecular mechanisms for the activity of PX-478, an antitumor inhibitor of the hypoxia-inducible factor-1alpha. Mol Cancer Ther 2008, 7:90-100.
-
(2008)
Mol Cancer Ther
, vol.7
, pp. 90-100
-
-
Koh, M.Y.1
Spivak-Kroizman, T.2
Venturini, S.3
-
126
-
-
1542398693
-
Randomized phase II study of multiple dose levels of CCI-779, a novel mammalian target of rapamycin kinase inhibitor, in patients with advanced refractory renal cell carcinoma
-
Atkins M.B., Hidalgo M., Stadler W.M., et al. Randomized phase II study of multiple dose levels of CCI-779, a novel mammalian target of rapamycin kinase inhibitor, in patients with advanced refractory renal cell carcinoma. J Clin Oncol 2004, 22:909-918.
-
(2004)
J Clin Oncol
, vol.22
, pp. 909-918
-
-
Atkins, M.B.1
Hidalgo, M.2
Stadler, W.M.3
-
127
-
-
0037862921
-
The effect of trastuzumab/docatexel combination on breast cancer angiogenesis: dichotomus effect predictable by the HIFI alpha/VEGF pre-treatment status?
-
Koukourakis M.I., Simopoulos C., Polychronidis A., et al. The effect of trastuzumab/docatexel combination on breast cancer angiogenesis: dichotomus effect predictable by the HIFI alpha/VEGF pre-treatment status?. Anticancer Res 2003, 23:1673-1680.
-
(2003)
Anticancer Res
, vol.23
, pp. 1673-1680
-
-
Koukourakis, M.I.1
Simopoulos, C.2
Polychronidis, A.3
-
128
-
-
33645499486
-
EGFR tyrosine kinase inhibitors decrease VEGF expression by both hypoxia-inducible factor (HIF)-1-independent and HIF-1-dependent mechanisms
-
Pore N., Jiang Z., Gupta A., Cerniglia G., Kao G.D., Maity A. EGFR tyrosine kinase inhibitors decrease VEGF expression by both hypoxia-inducible factor (HIF)-1-independent and HIF-1-dependent mechanisms. Cancer Res 2006, 66:3197-3204.
-
(2006)
Cancer Res
, vol.66
, pp. 3197-3204
-
-
Pore, N.1
Jiang, Z.2
Gupta, A.3
Cerniglia, G.4
Kao, G.D.5
Maity, A.6
-
129
-
-
79955658924
-
-
Necrosis related HIF-1α expression predicts prognosis in patients with endometrioid endometrial carcinoma. BMC Cancer; in press.
-
Seeber LMS, Horrée N, Van der Groep P, Van der Wall E, Verheijen RHM, Van Diest PJ. Necrosis related HIF-1α expression predicts prognosis in patients with endometrioid endometrial carcinoma. BMC Cancer; in press.
-
-
-
Seeber, L.M.S.1
Horrée, N.2
Van der Groep, P.3
Van der Wall, E.4
Verheijen, R.H.M.5
Van Diest, P.J.6
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