Tumor hypoxia in pelvic recurrences of cervical cancer

International Journal of Cancer

Volumn 79, Issue 4, 1998, Pages 365-369

  Höckel, Michael ^b   Schlenger, Karlheinz ^a   Höckel, Susanne ^a   Aral, Billur ^a   Schäffer, Uwe ^a   Vaupel, Peter ^a  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

^b UNIVERSITY OF LEIPZIG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CARBOPLATIN; CISPLATIN; FLUOROURACIL;

ADULT; AGED; ARTICLE; CANCER RECURRENCE; CANCER SURVIVAL; FEMALE; GYNECOLOGIC CANCER; HUMAN; HYPOXIA; MAJOR CLINICAL STUDY; MULTIMODALITY CANCER THERAPY; PRIORITY JOURNAL; TREATMENT OUTCOME; TUMOR CELL; UTERINE CERVIX CANCER;

ADENOCARCINOMA; ADULT; AGED; CARCINOMA, ADENOSQUAMOUS; CARCINOMA, SQUAMOUS CELL; FEMALE; HUMANS; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; OXYGEN; PARTIAL PRESSURE; PELVIC NEOPLASMS; POLAROGRAPHY; UTERINE CERVICAL NEOPLASMS;

EID: 0342857011     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0215(19980821)79:4<365::AID-IJC10>3.0.CO;2-4     Document Type: Article

References (22)

1. BRIZEL, D.M., SCULLY, S.P., HARRELSON, J.M., LAYFIELD, L.J., BEAN, J.M., PROSNITZ, L.R. and DEWHIRST, W.M., Tumor oxygenation predicts the likelihood of distant metastases in human soft tissue sarcoma. Cancer Res., 56, 941-943 (1996).
2. FENTON, B.M., MOHAMMAD, F.K. and SIEMANN, D.W., Should direct measurements of tumor oxygenation relate to the radiobiological hypoxic fraction of a tumor? Int. J. Radiat. Oncol. Biol. Phys., 33, 365-373 (1995).
3. GIACCIA, A.J., Hypoxic stress proteins: survival of the fittest. Semin. Radiat. Oncol., 6, 46-58 (1996).
4. GRAEBER, T.G., OSMANINAN, C., JACKS, T., HOUSMAN, D.E., KOCH, C.K., LOWE, S.W. and GIACCIA, A.J., Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumors. Nature (Lond.), 379, 88-91 (1996).
5. 1-phase by low oxygen conditions is independent of p53 status. Mol. Cell Biol., 14, 6264-6277 (1994).
6. GRAY, L.H., CONGER, A.D., EBERT, M., HORNSEY, S. and SCOTT, O.C.A., The concentration of oxygen dissolved in tissues at the time of irradiation as a factor in radiotherapy. Brit. J. Radiol., 26, 638-648 (1953).
7. HEACOCK, C.S. and SUTHERLAND, R.M., Induction characteristics of oxygen regulated proteins. Int. J. Radiat. Oncol. Biol. Phys., 12, 1287-1290 (1986).
8. 2 predicts survival in advanced cancer of the uterine cervix. Radiother. Oncol., 26, 45-50 (19930).
9. HÖCKEL, M., SCHLENGER, K., ARAL, B., MITZE, M., SCHAFFER, U. and VAUPEL, P., Association between tumor hypoxia and malignant progression in advanced cancer of the uterine cervix. Cancer Res., 56, 4509-4515 (1996a).
10. HÖCKEL, M., SCHLENGER, K., HAMM, H., KNAPSTEIN, P.G., HOHENFELLNER, R. and RÖSLER, H.P., Five-year experience with combined operative and radiotherapeutic treatment of recurrent gynecologic tumors infiltrating the pelvic wall. Cancer, 77, 1918-1933 (1996b).
11. 2 tension measurements. Cancer Res., 51, 6098-6102 (1991).
12. HÖCKEL, M., SCHLENGER, K., MITZE, M., SCHÄFFER, U. and VAUPEL, P., Hypoxia and radiation response in human tumors. Semin. Radiat. Oncol., 6, 3-9 (1996c).
13. HÖCKEL, M., VORNDRAN, B., SCHLENGER, K., BAUSSMANN, E., KNAPSTEIN, P.G. and VAUPEL, P., Tumor oxygenation: a new predictive parameter in locally advanced cancer of the uterine cervix. Gynecol. Oncol., 51, 141-149 (1993b).
14. HORSMAN, M.R., KHALIL, A., NORDSMARK, M., GRAU, C. and OVERGAARD, J., Relationship between radiobiological hypoxia and direct estimates of tumor oxygenation in a mouse tumor model. Radiother. Oncol., 28, 69-71 (1993).
15. PLATE, K.H., BREIER, G., WEICH, H.A. and RISAU, W., Vascular endothelial growth factor is a potential tumor angiogenesis factor in human gliomas in vivo. Nature (Lond.), 359, 845-848 (1992).
16. RICE, G.G., HOY, C. and SCHIMKE, R.T., Transient hypoxia enhances the frequency of dihydrofolate reductase gene amplification in Chinese hamster ovary cells. Proc. nat. Acad. Sci. (Wash.), 83, 5978-5982 (1986).
17. RUSSO, C.A., WEBER, T.K., VOLPE, C.M., STOLER, D.L., PETRELLI, N.J., RODRIGUEZ-BIGAS, M., BURHANS, W.C. and ANDERSON, G.R., An anoxia inducible endonuclease and enhanced DNA breakage as contributors to genomic instability in cancer. Cancer Res., 55, 1122-1128 (1995).
18. SHWEIKI, D., ITIN, A., NEUFELD, G., GITAYGOREN, H. and KESHET, E., Patterns of expression of vascular endothelial growth factor (VEGF) and VEGF receptors in mice suggest a role in hormonally regulated angiogenesis. J. Clin. Invest., 91, 2235-2243 (1993).
19. SUTHERLAND, R.M., AUSSERER, W., MURPHY, B. and LADEROUTE, K., Tumor hypoxia and heterogeneity: challenges and opportunities for the future. Semin. Radiat. Oncol., 6, 59-70 (1996).
20. VAUPEL, P., KALLINOWSKI, F. and OKUNIEFF, P., Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: a review. Cancer Res., 49, 6449-6465 (1989).
21. YOUNG, S.D., MARSHALL, R.S. and HILL, R.P., Hypoxia induces DNA overreplication and enhances metastatic potential of murine tumor cells. Proc. nat. Acad. Sci. (Wash.), 85, 9533-9537 (1988).
22. ZYWIETZ, F., REEKER, W. and KOCHS, E., Tumor oxygenation in a transplanted rat rhabdomyosarcoma during fractionated irradiation. Int. J. Radiat. Oncol. Biol. Phys., 32, 1391-1400 (1995).