-
1
-
-
0025080230
-
Growth regulation of the vascular system: Evidence for a metabolic hypothesis
-
ADAIR, T. H., GAY, W. J. AND MONTANI, J.-P. (1990). Growth regulation of the vascular system: evidence for a metabolic hypothesis. Am. J. Physiol. 259, 393-404.
-
(1990)
Am. J. Physiol.
, vol.259
, pp. 393-404
-
-
Adair, T.H.1
Gay, W.J.2
Montani, J.-P.3
-
2
-
-
0029803552
-
An essential role for p300/CBP in the cellular response to hypoxia
-
ARANY, Z., HUANG, L. E., ECKNER, R., BHATTACHARYA, S., JIANG, C., GOLDBERG, M. A., BUNN, H. F. AND LIVINGSTON, D. M. (1996). An essential role for p300/CBP in the cellular response to hypoxia. Proc. natn. Acad. Sci. U.S.A. 93, 12969-12973.
-
(1996)
Proc. Natn. Acad. Sci. U.S.A.
, vol.93
, pp. 12969-12973
-
-
Arany, Z.1
Huang, L.E.2
Eckner, R.3
Bhattacharya, S.4
Jiang, C.5
Goldberg, M.A.6
Bunn, H.F.7
Livingston, D.M.8
-
3
-
-
0026049416
-
Enhancer element at the 3′-flanking region controls transcriptional response to hypoxia in the human erythropoietin gene
-
BECK, I., RAMIREZ, S., WEINMANN, R. AND CARO, J. (1991). Enhancer element at the 3′-flanking region controls transcriptional response to hypoxia in the human erythropoietin gene. J. biol. Chem. 266, 15563-15566.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 15563-15566
-
-
Beck, I.1
Ramirez, S.2
Weinmann, R.3
Caro, J.4
-
4
-
-
0026494916
-
Hypoxic induction of the human erythropoietin gene: Cooperation between the promoter and enhancer, each of which contains steroid receptor response elements
-
BLANCHARD, K. L., ACQUAVIVA, A. M., GALSON, D. L. AND BUNN, H. F. (1992). Hypoxic induction of the human erythropoietin gene: cooperation between the promoter and enhancer, each of which contains steroid receptor response elements. Molec. cell. Biol. 12, 5373-5385.
-
(1992)
Molec. Cell. Biol.
, vol.12
, pp. 5373-5385
-
-
Blanchard, K.L.1
Acquaviva, A.M.2
Galson, D.L.3
Bunn, H.F.4
-
5
-
-
0028972768
-
Cell-specificity and signaling pathway of endothelin-1 gene regulation by hypoxia
-
BODI, I., BISHOPRIC, N. H., DISCHER, D. J., WU, X. AND WEBSTER, K. A. (1995). Cell-specificity and signaling pathway of endothelin-1 gene regulation by hypoxia. Cardiovasc. Res. 30, 975-984.
-
(1995)
Cardiovasc. Res.
, vol.30
, pp. 975-984
-
-
Bodi, I.1
Bishopric, N.H.2
Discher, D.J.3
Wu, X.4
Webster, K.A.5
-
6
-
-
0029842459
-
Oxygen sensing and molecular adaptation to hypoxia
-
BUNN, H. F. AND POYTON, R. O. (1996). Oxygen sensing and molecular adaptation to hypoxia. Physiol. Rev. 76, 839-885.
-
(1996)
Physiol. Rev.
, vol.76
, pp. 839-885
-
-
Bunn, H.F.1
Poyton, R.O.2
-
7
-
-
0022606620
-
Determination of serum immunoreactive erythropoietin in the investigation of erythrocytosis
-
COTES, P. M., DORÉ, C. J., LIU YIN, J. A., LEWIS, S. M., MESSINEZY, M., PEARSON, T. C. AND REID, C. (1986). Determination of serum immunoreactive erythropoietin in the investigation of erythrocytosis. New Engl. J. Med. 315, 283-287.
-
(1986)
New Engl. J. Med.
, vol.315
, pp. 283-287
-
-
Cotes, P.M.1
Doré, C.J.2
Liu Yin, J.A.3
Lewis, S.M.4
Messinezy, M.5
Pearson, T.C.6
Reid, C.7
-
8
-
-
0026577610
-
Regulation of tyrosine hydroxylase gene expression in the rat carotid body by hypoxia
-
CZYZYK-KRZESKA, M. F., BAYLISS, D. A., LAWSON, E. E. AND MILLHORN, D. E. (1992). Regulation of tyrosine hydroxylase gene expression in the rat carotid body by hypoxia. J. Neurochem. 58, 1538-1546.
-
(1992)
J. Neurochem.
, vol.58
, pp. 1538-1546
-
-
Czyzyk-Krzeska, M.F.1
Bayliss, D.A.2
Lawson, E.E.3
Millhorn, D.E.4
-
9
-
-
0030045543
-
Isoenzyme specific regulation of genes involved in energy metabolism by hypoxia, cobalt and desferrioxamine: Similarities with the regulation of erythropoietin
-
EBERT, B. L., GLEADLE, J. M., O'ROURKE, J. F., BARTLETT, S. M., POULTON, J. AND RATCLIFFE, P. J. (1995). Isoenzyme specific regulation of genes involved in energy metabolism by hypoxia, cobalt and desferrioxamine: similarities with the regulation of erythropoietin. Biochem. J. 313, 809-814.
-
(1995)
Biochem. J.
, vol.313
, pp. 809-814
-
-
Ebert, B.L.1
Gleadle, J.M.2
O'Rourke, J.F.3
Bartlett, S.M.4
Poulton, J.5
Ratcliffe, P.J.6
-
10
-
-
0027970536
-
Role of hydrogen peroxide in hypoxia-induced erythropoietin production
-
FANDREY, J., FREDE, S. AND JELKMANN, W. (1994). Role of hydrogen peroxide in hypoxia-induced erythropoietin production. Biochem. J. 303, 507-510.
-
(1994)
Biochem. J.
, vol.303
, pp. 507-510
-
-
Fandrey, J.1
Frede, S.2
Jelkmann, W.3
-
11
-
-
0028359320
-
Oxygen-regulated control elements in the phosphoglycerate kinase 1 and lactute dehydrogenase a genes: Similarities with the erythropoeitin 3′ enhancer
-
FIRTH, J. D., EBERT, B. L., PUGH, C. W. AND RATCLIFFE, P. J. (1994). Oxygen-regulated control elements in the phosphoglycerate kinase 1 and lactute dehydrogenase A genes: similarities with the erythropoeitin 3′ enhancer. Proc. natn. Acad. Sci. U.S.A. 91, 6496-6500.
-
(1994)
Proc. Natn. Acad. Sci. U.S.A.
, vol.91
, pp. 6496-6500
-
-
Firth, J.D.1
Ebert, B.L.2
Pugh, C.W.3
Ratcliffe, P.J.4
-
12
-
-
0029101515
-
Hypoxic regulation of lactate dehydrogcnase A: Interaction between hypoxia inducible factor 1 and cyclic AMP response elements
-
FIRTH, J. D., EBERT, B. L. AND RATCLIFFE, P. J. (1995). Hypoxic regulation of lactate dehydrogcnase A: interaction between hypoxia inducible factor 1 and cyclic AMP response elements. J. biol. Chem. 270, 21021-21027.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 21021-21027
-
-
Firth, J.D.1
Ebert, B.L.2
Ratcliffe, P.J.3
-
13
-
-
0028967752
-
The orphan receptor hepatic nuclear factor 4 functions as a transcriptional activator for tissue- Specific and hypoxia-specific erythropoietin gene expression and is antagonized by EAR3/COUP-TFI
-
GALSON, D. L., TSUCHIYA, T., TENDLER, D. S., HUANG, E., REN, Y., OGURA, T. AND BUNN, H. F. (1995). The orphan receptor hepatic nuclear factor 4 functions as a transcriptional activator for tissue-specific and hypoxia-specific erythropoietin gene expression and is antagonized by EAR3/COUP-TFI. Molec. cell. Biol. 15, 2135-2144.
-
(1995)
Molec. Cell. Biol.
, vol.15
, pp. 2135-2144
-
-
Galson, D.L.1
Tsuchiya, T.2
Tendler, D.S.3
Huang, E.4
Ren, Y.5
Ogura, T.6
Bunn, H.F.7
-
14
-
-
0028843411
-
Regulation of angiogenic growth factor expression by hypoxia, transition metals and chelating agents
-
GLEADLE, J. M., EBERT, B. L., FIRTH, J. D. AND RATCLIFFE, P. J. (1995a). Regulation of angiogenic growth factor expression by hypoxia, transition metals and chelating agents. Am. J. Physiol. 268, C1362-C1368.
-
(1995)
Am. J. Physiol.
, vol.268
-
-
Gleadle, J.M.1
Ebert, B.L.2
Firth, J.D.3
Ratcliffe, P.J.4
-
15
-
-
0028844810
-
Diphenylene iodonium inhibits the induction of erythropoietin and other mammalian genes by hypoxia: Implications for the mechanism of oxygen sensing
-
GLEADLE, J. M., EBERT, B. L. AND RATCLIFFE, P. J. (1995b). Diphenylene iodonium inhibits the induction of erythropoietin and other mammalian genes by hypoxia: implications for the mechanism of oxygen sensing. Eur. J. Biochem. 234, 92-99.
-
(1995)
Eur. J. Biochem.
, vol.234
, pp. 92-99
-
-
Gleadle, J.M.1
Ebert, B.L.2
Ratcliffe, P.J.3
-
16
-
-
0024273450
-
Regulation of the erythropoietin gene: Evidence that the oxygen sensor is a heme protein
-
GOLDBERG, M. A., DUNNING, S. P. AND BUNN, H. F. (1988). Regulation of the erythropoietin gene: evidence that the oxygen sensor is a heme protein. Science 242, 1412-1415.
-
(1988)
Science
, vol.242
, pp. 1412-1415
-
-
Goldberg, M.A.1
Dunning, S.P.2
Bunn, H.F.3
-
17
-
-
0025972125
-
Erythropoietin mRNA levels are governed by both the rate of gene transcription and posttranscriptional events
-
GOLDBERG, M. A., GAUT, C. C. AND BUNN, H. F. (1991). Erythropoietin mRNA levels are governed by both the rate of gene transcription and posttranscriptional events. Blood 77, 271-277.
-
(1991)
Blood
, vol.77
, pp. 271-277
-
-
Goldberg, M.A.1
Gaut, C.C.2
Bunn, H.F.3
-
18
-
-
0242408897
-
The regulated expression of erythropoietin by two human hepatoma cell lines
-
GOLDBERG, M. A., GLASS, G. A., CUNNINGHAM, J. M. AND BUNN, H. F. (1987). The regulated expression of erythropoietin by two human hepatoma cell lines. Proc. natn. Acad. Sci. U.S.A. 84, 7972-7976.
-
(1987)
Proc. Natn. Acad. Sci. U.S.A.
, vol.84
, pp. 7972-7976
-
-
Goldberg, M.A.1
Glass, G.A.2
Cunningham, J.M.3
Bunn, H.F.4
-
19
-
-
0028095127
-
Similarities between the oxygen-sensing mechanisms regulating the expression of vascular endothelial growth factor and erythropoietin
-
GOLDBERG, M. A. AND SCHNEIDER, T. J. (1994). Similarities between the oxygen-sensing mechanisms regulating the expression of vascular endothelial growth factor and erythropoietin. J. biol. Chem. 269, 4355-4359.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 4355-4359
-
-
Goldberg, M.A.1
Schneider, T.J.2
-
20
-
-
0028053910
-
Carotid body chemoreceptors: From natural stimuli to sensory discharges
-
GONZALEZ, C., ALMARAZ, L., OBESO, A. AND RIGUAL, R. (1994). Carotid body chemoreceptors: from natural stimuli to sensory discharges. Physiol. Rev. 74, 829-877.
-
(1994)
Physiol. Rev.
, vol.74
, pp. 829-877
-
-
Gonzalez, C.1
Almaraz, L.2
Obeso, A.3
Rigual, R.4
-
21
-
-
1842309184
-
Single-step selection of clones of a mouse hepatoma line deficient in aryl hydrocarbon hydroxylase
-
HANKINSON, O. (1979). Single-step selection of clones of a mouse hepatoma line deficient in aryl hydrocarbon hydroxylase. Proc. natn. Acad. Sci. U.S.A. 76, 373-376.
-
(1979)
Proc. Natn. Acad. Sci. U.S.A.
, vol.76
, pp. 373-376
-
-
Hankinson, O.1
-
22
-
-
0025765508
-
Modulation by oxygen of the glucagon-dependent activation of the phosphoenolpyruvate carboxykinase gene in rat hepatocyte cultures
-
HELLKAMP, J., CHRIST, B., BASTIAN, H. AND JUNGERMANN, K. (1991). Modulation by oxygen of the glucagon-dependent activation of the phosphoenolpyruvate carboxykinase gene in rat hepatocyte cultures. Eur. J. Biochem. 198, 635-639.
-
(1991)
Eur. J. Biochem.
, vol.198
, pp. 635-639
-
-
Hellkamp, J.1
Christ, B.2
Bastian, H.3
Jungermann, K.4
-
23
-
-
0025906014
-
Cloning of a factor required for activity of the Ah (Dioxin) receptor
-
HOFFMAN, E. C., REYES, H., CHU, F.-F., SANDER, F., CONLEY, L. H., BROOKS, B. A. AND HANKINSON, O. (1991). Cloning of a factor required for activity of the Ah (Dioxin) receptor. Science 252, 954-958.
-
(1991)
Science
, vol.252
, pp. 954-958
-
-
Hoffman, E.C.1
Reyes, H.2
Chu, F.-F.3
Sander, F.4
Conley, L.H.5
Brooks, B.A.6
Hankinson, O.7
-
24
-
-
0030887045
-
Characterization of a subset of the basic-helix-loop-helix-PAS superfamily that interacts with components of the dioxin signaling pathway
-
HOGENESCH, J. B., CHAN, W. K., JACKIW, V. H., BROWN, R. C., GU, Y.-Z., PRAY-GRANT, M., PERDEW, G. H. AND BRADFIELD, C. A. (1997). Characterization of a subset of the basic-helix-loop-helix-PAS superfamily that interacts with components of the dioxin signaling pathway. J. biol. Chem. 272, 8581-8593.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 8581-8593
-
-
Hogenesch, J.B.1
Chan, W.K.2
Jackiw, V.H.3
Brown, R.C.4
Gu, Y.-Z.5
Pray-Grant, M.6
Perdew, G.H.7
Bradfield, C.A.8
-
25
-
-
0029753008
-
Activation of hypoxia-inducible transcription factor depends primarily on redox-sensitive stabilization of its α subunit
-
HUANG, L. E., ARANY, Z., LIVINGSTON, D. M. AND BUNN, H. F. (1996). Activation of hypoxia-inducible transcription factor depends primarily on redox-sensitive stabilization of its α subunit. J. biol. Chem. 271, 32253-32259.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 32253-32259
-
-
Huang, L.E.1
Arany, Z.2
Livingston, D.M.3
Bunn, H.F.4
-
26
-
-
0027184569
-
PAS is a dimerization domain common to Drosophila period and several transcription factors
-
HUANG, Z. J., EDERY, I. AND ROSBASH, M. (1993). PAS is a dimerization domain common to Drosophila period and several transcription factors. Nature 364, 259-262.
-
(1993)
Nature
, vol.364
, pp. 259-262
-
-
Huang, Z.J.1
Edery, I.2
Rosbash, M.3
-
27
-
-
0029944965
-
Dimerization, DNA binding and transactivation properties of hypoxia-inducible factor 1
-
JIANG, B.-H., RUE, E., WANG, G. L., ROE, R. AND SEMENZA, G. L. (1996). Dimerization, DNA binding and transactivation properties of hypoxia-inducible factor 1. J. biol. Chem. 271, 17771-17778.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 17771-17778
-
-
Jiang, B.-H.1
Rue, E.2
Wang, G.L.3
Roe, R.4
Semenza, G.L.5
-
28
-
-
0028985793
-
Zonation of metabolism and gene expression in liver
-
JUNGERMANN, K. (1995). Zonation of metabolism and gene expression in liver. Histochemistry 103, 81-91.
-
(1995)
Histochemistry
, vol.103
, pp. 81-91
-
-
Jungermann, K.1
-
29
-
-
0027228302
-
A ferro-heme protein senses oxygen levels, which modulate the glucagon-dependent activation of the phosphoenolpyruvate carboxykinase gene in rat hepatocyte cultures
-
KIETZMANN, T., SCHMIDT, H., UNTHAN, F. K., PROBST, I. AND JUNGERMANN, K. (1993). A ferro-heme protein senses oxygen levels, which modulate the glucagon-dependent activation of the phosphoenolpyruvate carboxykinase gene in rat hepatocyte cultures. Biochem. biophys. Res. Commun. 195, 792-798.
-
(1993)
Biochem. Biophys. Res. Commun.
, vol.195
, pp. 792-798
-
-
Kietzmann, T.1
Schmidt, H.2
Unthan, F.K.3
Probst, I.4
Jungermann, K.5
-
30
-
-
0025050735
-
Oxygen tension regulates the expression of the platelet-derived growth factor-β chain gene in human endothelial cells
-
KOUREMBANAS, S., HANNAN, R. L. AND FALLER, D. V. (1990). Oxygen tension regulates the expression of the platelet-derived growth factor-β chain gene in human endothelial cells. J. clin. Invest. 86, 670-674.
-
(1990)
J. Clin. Invest.
, vol.86
, pp. 670-674
-
-
Kourembanas, S.1
Hannan, R.L.2
Faller, D.V.3
-
31
-
-
0031041377
-
Hypoxia-inducible factor-1 mediates transcriptional activation of the heme oxygenase-1 gene in response to hypoxia
-
LEE, P. J., JIANG, B.-H., CHIN, B. Y., IYER, N. V., ALAM, J., SEMENZA, G. L. AND CHOI, A. M. K. (1997). Hypoxia-inducible factor-1 mediates transcriptional activation of the heme oxygenase-1 gene in response to hypoxia. J. biol. Chem. 272, 5375-5381.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 5375-5381
-
-
Lee, P.J.1
Jiang, B.-H.2
Chin, B.Y.3
Iyer, N.V.4
Alam, J.5
Semenza, G.L.6
Choi, A.M.K.7
-
32
-
-
0025951716
-
Serial immunoreactive erythropoietin levels in autologous blood donors
-
LORENTZ, A., JENDRISSEK, A., ECKARDT, K.-U., SCHIPPLICK, M., OSSWALD, P. M. AND KURTZ, A. (1991). Serial immunoreactive erythropoietin levels in autologous blood donors. Transfusion 31, 650-654.
-
(1991)
Transfusion
, vol.31
, pp. 650-654
-
-
Lorentz, A.1
Jendrissek, A.2
Eckardt, K.-U.3
Schipplick, M.4
Osswald, P.M.5
Kurtz, A.6
-
33
-
-
0027959825
-
Hypoxia and cobalt stimulate lactate dehydrogenase (LDH) activity in vascular smooth muscle cells
-
MARTI, H. H., JUNG, H. H., PFEILSCHIFTER, J. AND BAUER, C. (1994). Hypoxia and cobalt stimulate lactate dehydrogenase (LDH) activity in vascular smooth muscle cells. Pflügers Arch. 429, 216-222.
-
(1994)
Pflügers Arch.
, vol.429
, pp. 216-222
-
-
Marti, H.H.1
Jung, H.H.2
Pfeilschifter, J.3
Bauer, C.4
-
34
-
-
0030816109
-
Hypoxia inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth
-
MAXWELL, P. H., DACHS, G. U., GLEADLE, J. M., NICHOLLS, L. G., HARRIS, A. L., STRATFORD, I. J., HANKINSON, O., PUGH, C. W. AND RATCLIFFE, P. J. (1997). Hypoxia inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth. Proc. natn. Acad. Sci. U.S.A. 94, 8104-8109.
-
(1997)
Proc. Natn. Acad. Sci. U.S.A.
, vol.94
, pp. 8104-8109
-
-
Maxwell, P.H.1
Dachs, G.U.2
Gleadle, J.M.3
Nicholls, L.G.4
Harris, A.L.5
Stratford, I.J.6
Hankinson, O.7
Pugh, C.W.8
Ratcliffe, P.J.9
-
35
-
-
0027461553
-
Inducible operation of the erythropoietin 3′ enhancer in multiple cell lines: Evidence for a widespread oxygen sensing mechanism
-
MAXWELL, P. H., PUGH, C. W. AND RATCLIFFE, P. J. (1993). Inducible operation of the erythropoietin 3′ enhancer in multiple cell lines: evidence for a widespread oxygen sensing mechanism. Proc. natn. Acad. Sci. U.S.A. 90, 2423-2427.
-
(1993)
Proc. Natn. Acad. Sci. U.S.A.
, vol.90
, pp. 2423-2427
-
-
Maxwell, P.H.1
Pugh, C.W.2
Ratcliffe, P.J.3
-
36
-
-
0029681850
-
Oncogenic transformation and hypoxia synergistically act to modulate vascular endothelial growth factor expression
-
MAZURE, N. M., CHEN, E. Y., YEH, P., LADEROUTE, K. R. AND GIACCIA, A. J. (1996). Oncogenic transformation and hypoxia synergistically act to modulate vascular endothelial growth factor expression. Cancer Res. 56, 3436-3440.
-
(1996)
Cancer Res.
, vol.56
, pp. 3436-3440
-
-
Mazure, N.M.1
Chen, E.Y.2
Yeh, P.3
Laderoute, K.R.4
Giaccia, A.J.5
-
37
-
-
0027938194
-
Hypoxia inhibits expression of eNOS via transcriptional and posttranscriptional mechanisms
-
MCQUILLAN, L. P., LEUNG, G. K., MARSDEN, P. A., KOSTYK, S. K. AND KOUREMBANAS, S. (1994). Hypoxia inhibits expression of eNOS via transcriptional and posttranscriptional mechanisms. Am. J. Physiol. 267, H1921-H1927.
-
(1994)
Am. J. Physiol.
, vol.267
-
-
Mcquillan, L.P.1
Leung, G.K.2
Marsden, P.A.3
Kostyk, S.K.4
Kourembanas, S.5
-
38
-
-
0028786601
-
A hypoxia-responsive element mediates a novel pathway of activation of the inducible nitric oxide synthase promoter
-
MELILLO, G., MUSSO, T., SICA, A., TAYLOR, L. S., COX, G. W. AND VARESIO, L. (1995). A hypoxia-responsive element mediates a novel pathway of activation of the inducible nitric oxide synthase promoter. J. exp. Med. 182, 1683-1693.
-
(1995)
J. Exp. Med.
, vol.182
, pp. 1683-1693
-
-
Melillo, G.1
Musso, T.2
Sica, A.3
Taylor, L.S.4
Cox, G.W.5
Varesio, L.6
-
39
-
-
0029891739
-
Drosophila melanogaster SL2 cells contain a hypoxically inducible DNa binding complex which recognises mammalian HIF-1 binding sites
-
NAGAO, M., EBERT, B. L., RATCLIFFE, P. J. AND PUGH, C. W. (1996). Drosophila melanogaster SL2 cells contain a hypoxically inducible DNA binding complex which recognises mammalian HIF-1 binding sites. FEBS Lett. 387, 161-166.
-
(1996)
FEBS Lett.
, vol.387
, pp. 161-166
-
-
Nagao, M.1
Ebert, B.L.2
Ratcliffe, P.J.3
Pugh, C.W.4
-
40
-
-
0030012683
-
The Drosophila melanogaster similar bHLH-PAS gene encodes a protein related to human hypoxia-inducible factor 1α and Drosophila single-minded
-
in Press
-
NAMBU, J. R., CHEN, W., HU, S. AND CREWS, S. T. (1996). The Drosophila melanogaster similar bHLH-PAS gene encodes a protein related to human hypoxia-inducible factor 1α and Drosophila single-minded. Gene (in press).
-
(1996)
Gene
-
-
Nambu, J.R.1
Chen, W.2
Hu, S.3
Crews, S.T.4
-
41
-
-
0015302188
-
The effect of inhibitors of energy metabolism on erythropoietin production
-
NECAS, E. AND NEUWIRT, J. (1972). The effect of inhibitors of energy metabolism on erythropoietin production. J. Lab. clin. Med. 79, 388-396.
-
(1972)
J. Lab. Clin. Med.
, vol.79
, pp. 388-396
-
-
Necas, E.1
Neuwirt, J.2
-
42
-
-
0027479814
-
Studies on the inhibitory mechanism of iodonium compounds with special reference to neutrophil NADPH oxidase
-
O'DONNELL, V. B., TEW, D. G., JONES, O. T. G. AND ENGLAND, P. J. (1993). Studies on the inhibitory mechanism of iodonium compounds with special reference to neutrophil NADPH oxidase. Biochem. J. 290, 41-49.
-
(1993)
Biochem. J.
, vol.290
, pp. 41-49
-
-
O'Donnell, V.B.1
Tew, D.G.2
Jones, O.T.G.3
England, P.J.4
-
43
-
-
0029858079
-
Identification of hypoxically inducible mRNAs in Hela cells using differential display PCR
-
O'ROURKE, J. F., PUGH, C. W., BARTLETT, S. M. AND RATCLIFFE, P. J. (1996). Identification of hypoxically inducible mRNAs in Hela cells using differential display PCR. Eur. J. Biochem. 241, 403-410.
-
(1996)
Eur. J. Biochem.
, vol.241
, pp. 403-410
-
-
O'Rourke, J.F.1
Pugh, C.W.2
Bartlett, S.M.3
Ratcliffe, P.J.4
-
44
-
-
0026446102
-
Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo
-
PLATE, K. H., BREIER, G., WEICH, H. A. AND RISAU, W. (1992). Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo. Nature 359, 845-848.
-
(1992)
Nature
, vol.359
, pp. 845-848
-
-
Plate, K.H.1
Breier, G.2
Weich, H.A.3
Risau, W.4
-
45
-
-
0028279870
-
Characterisation of functional domains within the mouse erythropoietin 3′ enhancer conveying oxygen-regulated responses in different cell lines
-
PUGH, C. W., EBERT, B. L., EBRAHIM, O. AND RATCLIFFE, P. J. (1994). Characterisation of functional domains within the mouse erythropoietin 3′ enhancer conveying oxygen-regulated responses in different cell lines. Biochim. biophys. Acta 1217, 297-306.
-
(1994)
Biochim. Biophys. Acta
, vol.1217
, pp. 297-306
-
-
Pugh, C.W.1
Ebert, B.L.2
Ebrahim, O.3
Ratcliffe, P.J.4
-
46
-
-
0030937718
-
Activation of hypoxia inducible factor-1; Definition of regulatory domains within the α subunit
-
PUGH, C. W., O'ROURKE, J. F., NAGAO, M., GLEADLE, J. M. AND RATCLIFFE, P. J. (1997). Activation of hypoxia inducible factor-1; Definition of regulatory domains within the α subunit. J. biol. Chem. 272, 11205-11214.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 11205-11214
-
-
Pugh, C.W.1
O'Rourke, J.F.2
Nagao, M.3
Gleadle, J.M.4
Ratcliffe, P.J.5
-
47
-
-
0025885693
-
Functional analysis of an oxygen-related transcriptional enhancer lying 3′ to the mouse erythropoietin gene
-
PUGH, C. W., TAN, C. C., JONES, R. W. AND RATCLIFFE, P. J. (1991). Functional analysis of an oxygen-related transcriptional enhancer lying 3′ to the mouse erythropoietin gene. Proc. natn. Acad. Sci. U.S.A. 88, 10553-10557.
-
(1991)
Proc. Natn. Acad. Sci. U.S.A.
, vol.88
, pp. 10553-10557
-
-
Pugh, C.W.1
Tan, C.C.2
Jones, R.W.3
Ratcliffe, P.J.4
-
48
-
-
0027377576
-
Molecular biology of erythropoietin
-
RATCLIFFE, P. J. (1993). Molecular biology of erythropoietin. Kidney Int. 44, 887-904.
-
(1993)
Kidney Int.
, vol.44
, pp. 887-904
-
-
Ratcliffe, P.J.1
-
49
-
-
0026625037
-
Identification of the Ah receptor nuclear translocator protein (Arnt) as a component of the DNa binding form of the Ah receptor
-
REYES, H., REISZ-PORSZASZ, S. AND HANKINSON, O. (1992). Identification of the Ah receptor nuclear translocator protein (Arnt) as a component of the DNA binding form of the Ah receptor. Science 256, 1193-1195.
-
(1992)
Science
, vol.256
, pp. 1193-1195
-
-
Reyes, H.1
Reisz-Porszasz, S.2
Hankinson, O.3
-
50
-
-
0030792094
-
Oxygen-regulated transferrin expression is mediated by hypoxia-inducible factor-1
-
in press
-
ROLFS, A., KVIETIKOVA, I., GASSMANN, M. AND WENGER, R. H. (1997). Oxygen-regulated transferrin expression is mediated by hypoxia-inducible factor-1. J. biol. Chem. (in press).
-
(1997)
J. Biol. Chem.
-
-
Rolfs, A.1
Kvietikova, I.2
Gassmann, M.3
Wenger, R.H.4
-
51
-
-
0029864024
-
Divergent regulation of vascular endothelial growth factor and of erythropoietin gene expression in vivo
-
SANDNER, P., GESS, B., WOLF, K. AND KURTZ, A. (1996). Divergent regulation of vascular endothelial growth factor and of erythropoietin gene expression in vivo. Pflügers Arch. 431, 905-912.
-
(1996)
Pflügers Arch.
, vol.431
, pp. 905-912
-
-
Sandner, P.1
Gess, B.2
Wolf, K.3
Kurtz, A.4
-
52
-
-
0030460724
-
Hypoxia response elements in the aldolase A, enolase 1 and lactate dehydrogenase a gene promoters contain essential binding sites for hypoxia-inducible factor 1
-
SEMENZA, G. L., JIAN, B.-H., LEUNG, S. W., PASSANTINO, R., CONCORDET, J.-P., MAIRE, P. AND GIALLONGO, A. (1996). Hypoxia response elements in the aldolase A, enolase 1 and lactate dehydrogenase A gene promoters contain essential binding sites for hypoxia-inducible factor 1. J. biol. Chem. 271, 32529-32537.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 32529-32537
-
-
Semenza, G.L.1
Jian, B.-H.2
Leung, S.W.3
Passantino, R.4
Concordet, J.-P.5
Maire, P.6
Giallongo, A.7
-
53
-
-
0026075610
-
Hypoxia-inducible nuclear factors bind to an enhancer element located 3′ to the human erythropoietin gene
-
SEMENZA, G. L., NEJFELT, M. K., CHI, S. M. AND ANTONARAKIS, S. E. (1991). Hypoxia-inducible nuclear factors bind to an enhancer element located 3′ to the human erythropoietin gene. Proc. natn. Acad. Sci. U.S.A. 88, 5680-5684.
-
(1991)
Proc. Natn. Acad. Sci. U.S.A.
, vol.88
, pp. 5680-5684
-
-
Semenza, G.L.1
Nejfelt, M.K.2
Chi, S.M.3
Antonarakis, S.E.4
-
54
-
-
0028068606
-
Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1
-
SEMENZA, G. L., ROTH, P. H., FANG, H.-M. AND WANG, G. L. (1994). Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1. J. biol. Chem. 269, 23757-23763.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 23757-23763
-
-
Semenza, G.L.1
Roth, P.H.2
Fang, H.-M.3
Wang, G.L.4
-
55
-
-
0026468180
-
A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation
-
SEMENZA, G. L. AND WANG, G. L. (1992). A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation. Molec. cell. Biol. 12, 5447-5454.
-
(1992)
Molec. Cell. Biol.
, vol.12
, pp. 5447-5454
-
-
Semenza, G.L.1
Wang, G.L.2
-
56
-
-
0026485002
-
Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis
-
SHWEIKI, D., ITIN, A., SOFFER, D. AND KESHET, E. (1992). Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis. Nature 359, 843-845.
-
(1992)
Nature
, vol.359
, pp. 843-845
-
-
Shweiki, D.1
Itin, A.2
Soffer, D.3
Keshet, E.4
-
57
-
-
0031020884
-
Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells
-
TIAN, H., MCKNIGHT, S. L. AND RUSSELL, D. W. (1997). Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells. Genes Dev. 11, 72-82.
-
(1997)
Genes Dev.
, vol.11
, pp. 72-82
-
-
Tian, H.1
Mcknight, S.L.2
Russell, D.W.3
-
59
-
-
0027136260
-
Desferrioxamine induces erythropoietin gene expression and hypoxia-inducible factor 1 DNA-binding activity: Implications for models of hypoxia signal transduction
-
WANG, G. L. AND SEMENZA, G. L. (1993a). Desferrioxamine induces erythropoietin gene expression and hypoxia-inducible factor 1 DNA-binding activity: implications for models of hypoxia signal transduction. Blood 82, 3610-3615.
-
(1993)
Blood
, vol.82
, pp. 3610-3615
-
-
Wang, G.L.1
Semenza, G.L.2
-
60
-
-
0027210562
-
General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxia
-
WANG, G. L. AND SEMENZA, G. L. (1993b). General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxia. Proc. natn. Acad. Sci. U.S.A. 90, 4304-4308.
-
(1993)
Proc. Natn. Acad. Sci. U.S.A.
, vol.90
, pp. 4304-4308
-
-
Wang, G.L.1
Semenza, G.L.2
-
61
-
-
0026566197
-
Variations in function and design: Testing symmorphosis in the respiratory system
-
WEIBEL, E. R., TAYLOR, C. R. AND HOPPELER, H. (1992). Variations in function and design: Testing symmorphosis in the respiratory system. Respir. Physiol. 87, 325-348.
-
(1992)
Respir. Physiol.
, vol.87
, pp. 325-348
-
-
Weibel, E.R.1
Taylor, C.R.2
Hoppeler, H.3
-
62
-
-
0028916976
-
The mechanisms of acute hypoxic pulmonary vasoconstriction: The tale of two channels
-
WEIR, E. K. AND ARCHER, S. L. (1995). The mechanisms of acute hypoxic pulmonary vasoconstriction: the tale of two channels. FASEB J. 9, 183-189.
-
(1995)
FASEB J.
, vol.9
, pp. 183-189
-
-
Weir, E.K.1
Archer, S.L.2
-
63
-
-
0029982422
-
Nucleotide sequence, chromosomal assignment and mRNA expression of mouse hypoxia-inducible factor-1α
-
WENGER, R. H., ROLFS, A., MARTI, H. H., GUÉNET, J.-L. AND GASSMANN, M. (1996). Nucleotide sequence, chromosomal assignment and mRNA expression of mouse hypoxia-inducible factor-1α. Biochem. biophys. Res. Commun. 223, 54-59.
-
(1996)
Biochem. Biophys. Res. Commun.
, vol.223
, pp. 54-59
-
-
Wenger, R.H.1
Rolfs, A.2
Marti, H.H.3
Guénet, J.-L.4
Gassmann, M.5
-
64
-
-
0030583293
-
In vivo expression of mRNAs encoding hypoxia-inducible factor 1
-
WIENER, C. M., BOOTH, G. AND SEMENZA, G. L. (1996). In vivo expression of mRNAs encoding hypoxia-inducible factor 1. Biochem. biophys. Res. Commun. 225, 485-188.
-
(1996)
Biochem. Biophys. Res. Commun.
, vol.225
, pp. 485-1188
-
-
Wiener, C.M.1
Booth, G.2
Semenza, G.L.3
-
65
-
-
0030025172
-
Trachealess encodes a bHLH-PAS protein that is an inducer of tracheal cell fates in Drosophila
-
WILK, R., WEIZMAN, I. AND SHILO, B.-Z. (1996). trachealess encodes a bHLH-PAS protein that is an inducer of tracheal cell fates in Drosophila. Genes Dev. 10, 93-102.
-
(1996)
Genes Dev.
, vol.10
, pp. 93-102
-
-
Wilk, R.1
Weizman, I.2
Shilo, B.-Z.3
-
66
-
-
0029888061
-
The role of aryl hydrocarbon receptor nuclear translocator (ARNT) in hypoxic induction of gene expression: Studies in ARNT deficient cells
-
WOOD, S. M., GLEADLE, J. M., PUGH, C. W., HANKINSON, O. AND RATCLIFFE, P. J. (1996). The role of aryl hydrocarbon receptor nuclear translocator (ARNT) in hypoxic induction of gene expression: studies in ARNT deficient cells. J. biol. Chem. 271, 15117-15123.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 15117-15123
-
-
Wood, S.M.1
Gleadle, J.M.2
Pugh, C.W.3
Hankinson, O.4
Ratcliffe, P.J.5
-
67
-
-
12644279862
-
Molecular characterization of two mammalian hHLH-PAS domain proteins selectively expressed in the central nervous system
-
ZHOU, Y.-D., BARNARD, M., TIAN, H., LI, X., RING, H. Z., FRANCKE, U., SHELTON, J., RICHARDSON, J., RUSSELL, D. W. AND MCKNIGHT, S. L. (1997). Molecular characterization of two mammalian hHLH-PAS domain proteins selectively expressed in the central nervous system. Proc. natn. Acad. Sci. U.S.A. 94, 713-718.
-
(1997)
Proc. Natn. Acad. Sci. U.S.A.
, vol.94
, pp. 713-718
-
-
Zhou, Y.-D.1
Barnard, M.2
Tian, H.3
Li, X.4
Ring, H.Z.5
Francke, U.6
Shelton, J.7
Richardson, J.8
Russell, D.W.9
Mcknight, S.L.10
|