UVC inhibits HIF-1α protein translation by a DNA damage- and topoisomerase I-independent pathway

Oncogene

Volumn 26, Issue 48, 2007, Pages 6875-6884

  Rapisarda, A ^a   Melillo, G ^a,b  

^a SAIC FREDERICK INC   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Cancer therapeutics; DNA damage; HIF 1; Topoisomerase; Translation; UVC

Indexed keywords

CISPLATIN; DNA TOPOISOMERASE; DOXORUBICIN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; TOPOTECAN;

ARTICLE; CANCER CELL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA DAMAGE; DNA REPLICATION; DRUG MECHANISM; HUMAN; HUMAN CELL; INHIBITION KINETICS; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RADIATION DOSE; RNA TRANSCRIPTION; RNA TRANSLATION; SIGNAL TRANSDUCTION; ULTRAVIOLET C RADIATION;

ANTINEOPLASTIC AGENTS; CELL CYCLE PROTEINS; CELL LINE, TUMOR; CELLS, CULTURED; CISPLATIN; DNA DAMAGE; DNA REPLICATION; DNA TOPOISOMERASES, TYPE I; DOSE-RESPONSE RELATIONSHIP, DRUG; DOXORUBICIN; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; IMMUNOBLOTTING; PROTEIN BIOSYNTHESIS; PROTEIN-SERINE-THREONINE KINASES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, SMALL INTERFERING; TOPOTECAN; TRANSCRIPTION, GENETIC; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P53; ULTRAVIOLET RAYS;

EID: 35348954836     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/sj.onc.1210489     Document Type: Article

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