-
2
-
-
0029051439
-
Hypoxia-inducible factor 1 is a basic helix-loop-helix-PAS heterodimer regulated by cellular oxygen tension
-
Wang GL, Jiang BH, Rue EA, et al. Hypoxia-inducible factor 1 is a basic helix-loop-helix-PAS heterodimer regulated by cellular oxygen tension. Proc Natl Acad Sci USA 1995;92:5510-5514.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 5510-5514
-
-
Wang, G.L.1
Jiang, B.H.2
Rue, E.A.3
-
3
-
-
0032581277
-
Role of HIF-1 alpha in hypoxia-mediated apoptosis, cell proliferation and tumor angiogenesis
-
Carmeliet P, Dor Y, Herbert JM, et al. Role of HIF-1 alpha in hypoxia-mediated apoptosis, cell proliferation and tumor angiogenesis. Nature 1998;394:485-490.
-
(1998)
Nature
, vol.394
, pp. 485-490
-
-
Carmeliet, P.1
Dor, Y.2
Herbert, J.M.3
-
4
-
-
0034743861
-
Oxygen status of malignant tumors: Pathogenesis of hypoxia and significance for tumor therapy
-
Vaupel P, Kelleher DK, Hockel M. Oxygen status of malignant tumors: pathogenesis of hypoxia and significance for tumor therapy. Semin Oncol 2001;28:29-35.
-
(2001)
Semin Oncol
, vol.28
, pp. 29-35
-
-
Vaupel, P.1
Kelleher, D.K.2
Hockel, M.3
-
5
-
-
0029775242
-
Association between tumor hypoxia and malignant progression in advanced cancer of the uterine cervix
-
Hockel M, Schlenger K, Aral B, et al. Association between tumor hypoxia and malignant progression in advanced cancer of the uterine cervix. Cancer Res 1996;56:4509-4515.
-
(1996)
Cancer Res
, vol.56
, pp. 4509-4515
-
-
Hockel, M.1
Schlenger, K.2
Aral, B.3
-
6
-
-
0030742027
-
Tumor hypoxia adversely affects the prognosis of carcinoma of the head and neck
-
Brizel DM, Sibley GS, Prosnitz LR, et al. Tumor hypoxia adversely affects the prognosis of carcinoma of the head and neck. Int J Radiat Oncol Biol Phys 1997;38:285-289.
-
(1997)
Int J Radiat Oncol Biol Phys
, vol.38
, pp. 285-289
-
-
Brizel, D.M.1
Sibley, G.S.2
Prosnitz, L.R.3
-
7
-
-
0032708195
-
Oxygenation of head and neck cancer: Changes during radiotherapy and impact on treatment outcome
-
Brizel DM, Dodge RK, Clough RW, et al. Oxygenation of head and neck cancer: changes during radiotherapy and impact on treatment outcome. Radiother Oncol 1999;53:113-117.
-
(1999)
Radiother Oncol
, vol.53
, pp. 113-117
-
-
Brizel, D.M.1
Dodge, R.K.2
Clough, R.W.3
-
8
-
-
0031716020
-
Oxygenation predicts radiation response and survival in patients with cervix cancer
-
Fyles AW, Milosevic M, Wong R, et al. Oxygenation predicts radiation response and survival in patients with cervix cancer. Radiother Oncol 1998;48:149-156.
-
(1998)
Radiother Oncol
, vol.48
, pp. 149-156
-
-
Fyles, A.W.1
Milosevic, M.2
Wong, R.3
-
9
-
-
0030022252
-
Tumor oxygenation predicts for the likelihood of distant metastases in human soft tissue sarcoma
-
Brizel DM, Scully SP, Harrelson JM, et al. Tumor oxygenation predicts for the likelihood of distant metastases in human soft tissue sarcoma. Cancer Res 1996;56:941-943.
-
(1996)
Cancer Res
, vol.56
, pp. 941-943
-
-
Brizel, D.M.1
Scully, S.P.2
Harrelson, J.M.3
-
10
-
-
0035917618
-
Hypoxia in human soft tissue sarcomas: Adverse impact on survival and no association with p53 mutations
-
Nordsmark M, Alsner J, Keller J, et al. Hypoxia in human soft tissue sarcomas: adverse impact on survival and no association with p53 mutations. Br J Cancer 2001;84:1070-1075.
-
(2001)
Br J Cancer
, vol.84
, pp. 1070-1075
-
-
Nordsmark, M.1
Alsner, J.2
Keller, J.3
-
11
-
-
0036721256
-
Association of hypoxia-inducible factors 1α and 2α with activated angiogenic pathways and prognosis in patients with endometrial carcinoma
-
Sivridis B, Giatromanolaki A, Gatter K, et al. Association of hypoxia-inducible factors 1α and 2α with activated angiogenic pathways and prognosis in patients with endometrial carcinoma. Cancer 2002;95:1055-1063.
-
(2002)
Cancer
, vol.95
, pp. 1055-1063
-
-
Sivridis, B.1
Giatromanolaki, A.2
Gatter, K.3
-
12
-
-
0033954247
-
Regulation of tumor angiogenesis by p53-induced degradation of hypoxia-inducible factor-1 alpha
-
Ravi R, Mookerjee B, Bhujwalla ZM, et al. Regulation of tumor angiogenesis by p53-induced degradation of hypoxia-inducible factor-1 alpha. Genes Dev 2000;14:34-44.
-
(2000)
Genes Dev
, vol.14
, pp. 34-44
-
-
Ravi, R.1
Mookerjee, B.2
Bhujwalla, Z.M.3
-
13
-
-
0344736649
-
Molecular and histopathologic predictors of distant failure in endometrial cancer
-
Mariani A, Sebo TJ, Webb MJ, et al. Molecular and histopathologic predictors of distant failure in endometrial cancer. Cancer Detect and Prev 2003;27:434-441.
-
(2003)
Cancer Detect and Prev
, vol.27
, pp. 434-441
-
-
Mariani, A.1
Sebo, T.J.2
Webb, M.J.3
-
14
-
-
0032872152
-
p53 expression as a prognostic indicator of 5-year survival in endometrial cancer
-
Geisler JP, Geisler HE, Wiemann MC, et al. p53 expression as a prognostic indicator of 5-year survival in endometrial cancer. Gynecol Oncol 1999;74:468-471.
-
(1999)
Gynecol Oncol
, vol.74
, pp. 468-471
-
-
Geisler, J.P.1
Geisler, H.E.2
Wiemann, M.C.3
-
15
-
-
1842582530
-
A significance of immunohistochemical determination of steroid receptors, cell proliferation factor Ki-67 and protein p53 in endometrial carcinoma
-
Oreskovic S, Babic D, Kalafatic D, et al. A significance of immunohistochemical determination of steroid receptors, cell proliferation factor Ki-67 and protein p53 in endometrial carcinoma. Gynecol Oncol 2004;93:34-40.
-
(2004)
Gynecol Oncol
, vol.93
, pp. 34-40
-
-
Oreskovic, S.1
Babic, D.2
Kalafatic, D.3
-
16
-
-
0033571682
-
Overexpression of hypoxia-inducible factor 1α in common human cancers and their metastases
-
Zhong H, De Marzo A, Laughner E, et al. Overexpression of hypoxia-inducible factor 1α in common human cancers and their metastases. Cancer Res 1999;59:5830-5835.
-
(1999)
Cancer Res
, vol.59
, pp. 5830-5835
-
-
Zhong, H.1
De Marzo, A.2
Laughner, E.3
-
17
-
-
0034896068
-
Expression of hypoxia-inducible factor 1α in epithelial ovarian tumors: Its impact on prognosis and on response to chemotherapy
-
Birner P, Schindl M, Obermair A, et al. Expression of hypoxia-inducible factor 1α in epithelial ovarian tumors: its impact on prognosis and on response to chemotherapy. Clin Cancer Res 2001;7:1661-1668.
-
(2001)
Clin Cancer Res
, vol.7
, pp. 1661-1668
-
-
Birner, P.1
Schindl, M.2
Obermair, A.3
-
18
-
-
0141675101
-
The effect of cyclooxygenase-2 expression on tumor vascularity in advanced stage ovarian serous carcinoma
-
Rouba Ali-Fehmi MC, Khalifeh I, Malone JM, et al. The effect of cyclooxygenase-2 expression on tumor vascularity in advanced stage ovarian serous carcinoma. Cancer 2003;98:1423-1429.
-
(2003)
Cancer
, vol.98
, pp. 1423-1429
-
-
Rouba Ali-Fehmi, M.C.1
Khalifeh, I.2
Malone, J.M.3
-
19
-
-
0033932042
-
Pretreatment assessment of prognostic indicators in endometrial cancer
-
Mariani A, Sebo TJ, Katzmann JA, et al. Pretreatment assessment of prognostic indicators in endometrial cancer. Am J Obstet Gynecol 2000;182:1535-1544.
-
(2000)
Am J Obstet Gynecol
, vol.182
, pp. 1535-1544
-
-
Mariani, A.1
Sebo, T.J.2
Katzmann, J.A.3
-
20
-
-
0035860147
-
Relation of hypoxia inducible factor 1alpha and 2 alpha in operable non-small cell lung cancer to angiogenic/molecular profile of tumors and survival
-
Giatromanolaki A, Koukourakis MI, Sivridis E, et al. Relation of hypoxia inducible factor 1alpha and 2 alpha in operable non-small cell lung cancer to angiogenic/molecular profile of tumors and survival. Br J Cancer 2001;85:881-890.
-
(2001)
Br J Cancer
, vol.85
, pp. 881-890
-
-
Giatromanolaki, A.1
Koukourakis, M.I.2
Sivridis, E.3
-
21
-
-
0038300418
-
Significant correlation of hypoxia-inducible factor-1alpha with treatment outcome in cervical cancer treated with radical radiotherapy
-
Burri P, Djonov V, Aebersold DM, et al. Significant correlation of hypoxia-inducible factor-1alpha with treatment outcome in cervical cancer treated with radical radiotherapy. Int J Gynecol Oncol Biol Phys 2003;56:494-501.
-
(2003)
Int J Gynecol Oncol Biol Phys
, vol.56
, pp. 494-501
-
-
Burri, P.1
Djonov, V.2
Aebersold, D.M.3
-
22
-
-
2442650576
-
Prognostic significance of erythropoietin expression in human endometrial carcinoma
-
Acs G, Xu X, Chu C, et al. Prognostic significance of erythropoietin expression in human endometrial carcinoma. Cancer. 2004;100:2376-2386.
-
(2004)
Cancer
, vol.100
, pp. 2376-2386
-
-
Acs, G.1
Xu, X.2
Chu, C.3
-
23
-
-
33845700081
-
Hypoxia-inducible nuclear factors bind to an enhancer element located 3′ to the human erythropoietin gene
-
Semenza GL, Nejfelt MK, Chi SM, et al. Hypoxia-inducible nuclear factors bind to an enhancer element located 3′ to the human erythropoietin gene. Proc Natl Acad Sci USA 1998;95:7987-7992.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 7987-7992
-
-
Semenza, G.L.1
Nejfelt, M.K.2
Chi, S.M.3
-
24
-
-
0036023422
-
Coexpression of hypoxia-inducible factors 1α and 2α, carbonic anhydarse IX, and vascular endothelial growth factor in nasopharyngeal carcinoma and relationship to survival
-
Hui EP, Chan A, Pezella F, et al. Coexpression of hypoxia-inducible factors 1α and 2α, carbonic anhydarse IX, and vascular endothelial growth factor in nasopharyngeal carcinoma and relationship to survival. Clin Cancer Res 2002;8:2595-2604.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 2595-2604
-
-
Hui, E.P.1
Chan, A.2
Pezella, F.3
-
25
-
-
33646157970
-
Phosphorylated KDR expression in endometrial cancer cells relates to HIF1alpha/VEGF pathway and unfavourable prognosis
-
Tumor and Angiogenesis Research Group
-
Giatromanolaki A, Koukourakis MI, Turley H, et al, Tumor and Angiogenesis Research Group. Phosphorylated KDR expression in endometrial cancer cells relates to HIF1alpha/VEGF pathway and unfavourable prognosis. Mod Pathol 2006;19:701-707.
-
(2006)
Mod Pathol
, vol.19
, pp. 701-707
-
-
Giatromanolaki, A.1
Koukourakis, M.I.2
Turley, H.3
-
26
-
-
0031724315
-
Identification of high-risk patients by assessment of nuclear Ki-67 expression in a prospective study of endometrial carcinomas
-
Salvesen HB, Iversen OE, Akslen LA. Identification of high-risk patients by assessment of nuclear Ki-67 expression in a prospective study of endometrial carcinomas. Clin Cancer Res 1998;4:2779-2785.
-
(1998)
Clin Cancer Res
, vol.4
, pp. 2779-2785
-
-
Salvesen, H.B.1
Iversen, O.E.2
Akslen, L.A.3
-
27
-
-
0032805760
-
MIB-1 in endometrial carcinoma: Prognostic significance with 5-year follow-up
-
Geisler JP, Geisler HE, Miller GA, et al. MIB-1 in endometrial carcinoma: prognostic significance with 5-year follow-up. Gynecol Oncol 1999;75:432-436.
-
(1999)
Gynecol Oncol
, vol.75
, pp. 432-436
-
-
Geisler, J.P.1
Geisler, H.E.2
Miller, G.A.3
-
28
-
-
0031012928
-
p53 gene mutations are common in uterine serous carcinoma and occur in their pathogenesis
-
Tashiro H, Isaacson C, Levine R, et al. p53 gene mutations are common in uterine serous carcinoma and occur in their pathogenesis. Am J Pathol 1997;150:177-185.
-
(1997)
Am J Pathol
, vol.150
, pp. 177-185
-
-
Tashiro, H.1
Isaacson, C.2
Levine, R.3
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