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Volumn 20, Issue 1, 2007, Pages 35-43

Increased expression of hypoxia-inducible factor 1α in type I and type II endometrial carcinomas

Author keywords

Endometrial carcinoma; High expression of HIF 1 ; Type I; Type II

Indexed keywords

ANTIBODY; C 1 ANTIBODY; DO7 ANTIBODY; H1 ALPHA67 ANTIBODY; HYPOXIA INDUCIBLE FACTOR 1ALPHA; K 2 ANTIBODY; KI 67 ANTIGEN; PARAFFIN; PROTEIN P53; VASCULOTROPIN;

EID: 33845710706     PISSN: 08933952     EISSN: 15300285     Source Type: Journal    
DOI: 10.1038/modpathol.3800718     Document Type: Article
Times cited : (44)

References (28)
  • 2
    • 0029051439 scopus 로고
    • Hypoxia-inducible factor 1 is a basic helix-loop-helix-PAS heterodimer regulated by cellular oxygen tension
    • Wang GL, Jiang BH, Rue EA, et al. Hypoxia-inducible factor 1 is a basic helix-loop-helix-PAS heterodimer regulated by cellular oxygen tension. Proc Natl Acad Sci USA 1995;92:5510-5514.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 5510-5514
    • Wang, G.L.1    Jiang, B.H.2    Rue, E.A.3
  • 3
    • 0032581277 scopus 로고    scopus 로고
    • Role of HIF-1 alpha in hypoxia-mediated apoptosis, cell proliferation and tumor angiogenesis
    • Carmeliet P, Dor Y, Herbert JM, et al. Role of HIF-1 alpha in hypoxia-mediated apoptosis, cell proliferation and tumor angiogenesis. Nature 1998;394:485-490.
    • (1998) Nature , vol.394 , pp. 485-490
    • Carmeliet, P.1    Dor, Y.2    Herbert, J.M.3
  • 4
    • 0034743861 scopus 로고    scopus 로고
    • Oxygen status of malignant tumors: Pathogenesis of hypoxia and significance for tumor therapy
    • Vaupel P, Kelleher DK, Hockel M. Oxygen status of malignant tumors: pathogenesis of hypoxia and significance for tumor therapy. Semin Oncol 2001;28:29-35.
    • (2001) Semin Oncol , vol.28 , pp. 29-35
    • Vaupel, P.1    Kelleher, D.K.2    Hockel, M.3
  • 5
    • 0029775242 scopus 로고    scopus 로고
    • Association between tumor hypoxia and malignant progression in advanced cancer of the uterine cervix
    • Hockel M, Schlenger K, Aral B, et al. Association between tumor hypoxia and malignant progression in advanced cancer of the uterine cervix. Cancer Res 1996;56:4509-4515.
    • (1996) Cancer Res , vol.56 , pp. 4509-4515
    • Hockel, M.1    Schlenger, K.2    Aral, B.3
  • 6
    • 0030742027 scopus 로고    scopus 로고
    • Tumor hypoxia adversely affects the prognosis of carcinoma of the head and neck
    • Brizel DM, Sibley GS, Prosnitz LR, et al. Tumor hypoxia adversely affects the prognosis of carcinoma of the head and neck. Int J Radiat Oncol Biol Phys 1997;38:285-289.
    • (1997) Int J Radiat Oncol Biol Phys , vol.38 , pp. 285-289
    • Brizel, D.M.1    Sibley, G.S.2    Prosnitz, L.R.3
  • 7
    • 0032708195 scopus 로고    scopus 로고
    • Oxygenation of head and neck cancer: Changes during radiotherapy and impact on treatment outcome
    • Brizel DM, Dodge RK, Clough RW, et al. Oxygenation of head and neck cancer: changes during radiotherapy and impact on treatment outcome. Radiother Oncol 1999;53:113-117.
    • (1999) Radiother Oncol , vol.53 , pp. 113-117
    • Brizel, D.M.1    Dodge, R.K.2    Clough, R.W.3
  • 8
    • 0031716020 scopus 로고    scopus 로고
    • Oxygenation predicts radiation response and survival in patients with cervix cancer
    • Fyles AW, Milosevic M, Wong R, et al. Oxygenation predicts radiation response and survival in patients with cervix cancer. Radiother Oncol 1998;48:149-156.
    • (1998) Radiother Oncol , vol.48 , pp. 149-156
    • Fyles, A.W.1    Milosevic, M.2    Wong, R.3
  • 9
    • 0030022252 scopus 로고    scopus 로고
    • Tumor oxygenation predicts for the likelihood of distant metastases in human soft tissue sarcoma
    • Brizel DM, Scully SP, Harrelson JM, et al. Tumor oxygenation predicts for the likelihood of distant metastases in human soft tissue sarcoma. Cancer Res 1996;56:941-943.
    • (1996) Cancer Res , vol.56 , pp. 941-943
    • Brizel, D.M.1    Scully, S.P.2    Harrelson, J.M.3
  • 10
    • 0035917618 scopus 로고    scopus 로고
    • Hypoxia in human soft tissue sarcomas: Adverse impact on survival and no association with p53 mutations
    • Nordsmark M, Alsner J, Keller J, et al. Hypoxia in human soft tissue sarcomas: adverse impact on survival and no association with p53 mutations. Br J Cancer 2001;84:1070-1075.
    • (2001) Br J Cancer , vol.84 , pp. 1070-1075
    • Nordsmark, M.1    Alsner, J.2    Keller, J.3
  • 11
    • 0036721256 scopus 로고    scopus 로고
    • Association of hypoxia-inducible factors 1α and 2α with activated angiogenic pathways and prognosis in patients with endometrial carcinoma
    • Sivridis B, Giatromanolaki A, Gatter K, et al. Association of hypoxia-inducible factors 1α and 2α with activated angiogenic pathways and prognosis in patients with endometrial carcinoma. Cancer 2002;95:1055-1063.
    • (2002) Cancer , vol.95 , pp. 1055-1063
    • Sivridis, B.1    Giatromanolaki, A.2    Gatter, K.3
  • 12
    • 0033954247 scopus 로고    scopus 로고
    • Regulation of tumor angiogenesis by p53-induced degradation of hypoxia-inducible factor-1 alpha
    • Ravi R, Mookerjee B, Bhujwalla ZM, et al. Regulation of tumor angiogenesis by p53-induced degradation of hypoxia-inducible factor-1 alpha. Genes Dev 2000;14:34-44.
    • (2000) Genes Dev , vol.14 , pp. 34-44
    • Ravi, R.1    Mookerjee, B.2    Bhujwalla, Z.M.3
  • 13
    • 0344736649 scopus 로고    scopus 로고
    • Molecular and histopathologic predictors of distant failure in endometrial cancer
    • Mariani A, Sebo TJ, Webb MJ, et al. Molecular and histopathologic predictors of distant failure in endometrial cancer. Cancer Detect and Prev 2003;27:434-441.
    • (2003) Cancer Detect and Prev , vol.27 , pp. 434-441
    • Mariani, A.1    Sebo, T.J.2    Webb, M.J.3
  • 14
    • 0032872152 scopus 로고    scopus 로고
    • p53 expression as a prognostic indicator of 5-year survival in endometrial cancer
    • Geisler JP, Geisler HE, Wiemann MC, et al. p53 expression as a prognostic indicator of 5-year survival in endometrial cancer. Gynecol Oncol 1999;74:468-471.
    • (1999) Gynecol Oncol , vol.74 , pp. 468-471
    • Geisler, J.P.1    Geisler, H.E.2    Wiemann, M.C.3
  • 15
    • 1842582530 scopus 로고    scopus 로고
    • A significance of immunohistochemical determination of steroid receptors, cell proliferation factor Ki-67 and protein p53 in endometrial carcinoma
    • Oreskovic S, Babic D, Kalafatic D, et al. A significance of immunohistochemical determination of steroid receptors, cell proliferation factor Ki-67 and protein p53 in endometrial carcinoma. Gynecol Oncol 2004;93:34-40.
    • (2004) Gynecol Oncol , vol.93 , pp. 34-40
    • Oreskovic, S.1    Babic, D.2    Kalafatic, D.3
  • 16
    • 0033571682 scopus 로고    scopus 로고
    • Overexpression of hypoxia-inducible factor 1α in common human cancers and their metastases
    • Zhong H, De Marzo A, Laughner E, et al. Overexpression of hypoxia-inducible factor 1α in common human cancers and their metastases. Cancer Res 1999;59:5830-5835.
    • (1999) Cancer Res , vol.59 , pp. 5830-5835
    • Zhong, H.1    De Marzo, A.2    Laughner, E.3
  • 17
    • 0034896068 scopus 로고    scopus 로고
    • Expression of hypoxia-inducible factor 1α in epithelial ovarian tumors: Its impact on prognosis and on response to chemotherapy
    • Birner P, Schindl M, Obermair A, et al. Expression of hypoxia-inducible factor 1α in epithelial ovarian tumors: its impact on prognosis and on response to chemotherapy. Clin Cancer Res 2001;7:1661-1668.
    • (2001) Clin Cancer Res , vol.7 , pp. 1661-1668
    • Birner, P.1    Schindl, M.2    Obermair, A.3
  • 18
    • 0141675101 scopus 로고    scopus 로고
    • The effect of cyclooxygenase-2 expression on tumor vascularity in advanced stage ovarian serous carcinoma
    • Rouba Ali-Fehmi MC, Khalifeh I, Malone JM, et al. The effect of cyclooxygenase-2 expression on tumor vascularity in advanced stage ovarian serous carcinoma. Cancer 2003;98:1423-1429.
    • (2003) Cancer , vol.98 , pp. 1423-1429
    • Rouba Ali-Fehmi, M.C.1    Khalifeh, I.2    Malone, J.M.3
  • 19
    • 0033932042 scopus 로고    scopus 로고
    • Pretreatment assessment of prognostic indicators in endometrial cancer
    • Mariani A, Sebo TJ, Katzmann JA, et al. Pretreatment assessment of prognostic indicators in endometrial cancer. Am J Obstet Gynecol 2000;182:1535-1544.
    • (2000) Am J Obstet Gynecol , vol.182 , pp. 1535-1544
    • Mariani, A.1    Sebo, T.J.2    Katzmann, J.A.3
  • 20
    • 0035860147 scopus 로고    scopus 로고
    • Relation of hypoxia inducible factor 1alpha and 2 alpha in operable non-small cell lung cancer to angiogenic/molecular profile of tumors and survival
    • Giatromanolaki A, Koukourakis MI, Sivridis E, et al. Relation of hypoxia inducible factor 1alpha and 2 alpha in operable non-small cell lung cancer to angiogenic/molecular profile of tumors and survival. Br J Cancer 2001;85:881-890.
    • (2001) Br J Cancer , vol.85 , pp. 881-890
    • Giatromanolaki, A.1    Koukourakis, M.I.2    Sivridis, E.3
  • 21
    • 0038300418 scopus 로고    scopus 로고
    • Significant correlation of hypoxia-inducible factor-1alpha with treatment outcome in cervical cancer treated with radical radiotherapy
    • Burri P, Djonov V, Aebersold DM, et al. Significant correlation of hypoxia-inducible factor-1alpha with treatment outcome in cervical cancer treated with radical radiotherapy. Int J Gynecol Oncol Biol Phys 2003;56:494-501.
    • (2003) Int J Gynecol Oncol Biol Phys , vol.56 , pp. 494-501
    • Burri, P.1    Djonov, V.2    Aebersold, D.M.3
  • 22
    • 2442650576 scopus 로고    scopus 로고
    • Prognostic significance of erythropoietin expression in human endometrial carcinoma
    • Acs G, Xu X, Chu C, et al. Prognostic significance of erythropoietin expression in human endometrial carcinoma. Cancer. 2004;100:2376-2386.
    • (2004) Cancer , vol.100 , pp. 2376-2386
    • Acs, G.1    Xu, X.2    Chu, C.3
  • 23
    • 33845700081 scopus 로고    scopus 로고
    • Hypoxia-inducible nuclear factors bind to an enhancer element located 3′ to the human erythropoietin gene
    • Semenza GL, Nejfelt MK, Chi SM, et al. Hypoxia-inducible nuclear factors bind to an enhancer element located 3′ to the human erythropoietin gene. Proc Natl Acad Sci USA 1998;95:7987-7992.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 7987-7992
    • Semenza, G.L.1    Nejfelt, M.K.2    Chi, S.M.3
  • 24
    • 0036023422 scopus 로고    scopus 로고
    • Coexpression of hypoxia-inducible factors 1α and 2α, carbonic anhydarse IX, and vascular endothelial growth factor in nasopharyngeal carcinoma and relationship to survival
    • Hui EP, Chan A, Pezella F, et al. Coexpression of hypoxia-inducible factors 1α and 2α, carbonic anhydarse IX, and vascular endothelial growth factor in nasopharyngeal carcinoma and relationship to survival. Clin Cancer Res 2002;8:2595-2604.
    • (2002) Clin Cancer Res , vol.8 , pp. 2595-2604
    • Hui, E.P.1    Chan, A.2    Pezella, F.3
  • 25
    • 33646157970 scopus 로고    scopus 로고
    • Phosphorylated KDR expression in endometrial cancer cells relates to HIF1alpha/VEGF pathway and unfavourable prognosis
    • Tumor and Angiogenesis Research Group
    • Giatromanolaki A, Koukourakis MI, Turley H, et al, Tumor and Angiogenesis Research Group. Phosphorylated KDR expression in endometrial cancer cells relates to HIF1alpha/VEGF pathway and unfavourable prognosis. Mod Pathol 2006;19:701-707.
    • (2006) Mod Pathol , vol.19 , pp. 701-707
    • Giatromanolaki, A.1    Koukourakis, M.I.2    Turley, H.3
  • 26
    • 0031724315 scopus 로고    scopus 로고
    • Identification of high-risk patients by assessment of nuclear Ki-67 expression in a prospective study of endometrial carcinomas
    • Salvesen HB, Iversen OE, Akslen LA. Identification of high-risk patients by assessment of nuclear Ki-67 expression in a prospective study of endometrial carcinomas. Clin Cancer Res 1998;4:2779-2785.
    • (1998) Clin Cancer Res , vol.4 , pp. 2779-2785
    • Salvesen, H.B.1    Iversen, O.E.2    Akslen, L.A.3
  • 27
    • 0032805760 scopus 로고    scopus 로고
    • MIB-1 in endometrial carcinoma: Prognostic significance with 5-year follow-up
    • Geisler JP, Geisler HE, Miller GA, et al. MIB-1 in endometrial carcinoma: prognostic significance with 5-year follow-up. Gynecol Oncol 1999;75:432-436.
    • (1999) Gynecol Oncol , vol.75 , pp. 432-436
    • Geisler, J.P.1    Geisler, H.E.2    Miller, G.A.3
  • 28
    • 0031012928 scopus 로고    scopus 로고
    • p53 gene mutations are common in uterine serous carcinoma and occur in their pathogenesis
    • Tashiro H, Isaacson C, Levine R, et al. p53 gene mutations are common in uterine serous carcinoma and occur in their pathogenesis. Am J Pathol 1997;150:177-185.
    • (1997) Am J Pathol , vol.150 , pp. 177-185
    • Tashiro, H.1    Isaacson, C.2    Levine, R.3


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