-
1
-
-
0032549811
-
A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis
-
DOI 10.1016/S0092-8674(00)81410-5
-
Puigserver P, Wu Z, Park CW, Graves R, Wright M and Spiegelman BM. A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis. Cell 1998, 92: 829-839. (Pubitemid 28155321)
-
(1998)
Cell
, vol.92
, Issue.6
, pp. 829-839
-
-
Puigserver, P.1
Wu, Z.2
Park, C.W.3
Graves, R.4
Wright, M.5
Spiegelman, B.M.6
-
2
-
-
0032589689
-
Activation of PPARγcoactivator-1 through transcription factor docking
-
Puigserver P, Adelmant G, Wu Z, Fan M, Xu J, O'Malley B and Spiegelman BM. Activation of PPARγcoactivator-1 through transcription factor docking. Science 1999, 286: 1368-1371.
-
(1999)
Science
, vol.286
, pp. 1368-1371
-
-
Puigserver, P.1
Adelmant, G.2
Wu, Z.3
Fan, M.4
Xu, J.5
O'Malley, B.6
Spiegelman, B.M.7
-
3
-
-
0344413490
-
Coordination of p300-mediated chromatin remodeling and TRAP/mediator function through coactivator PGC-1α
-
DOI 10.1016/S1097-2765(03)00391-5
-
Wallberg AE, Yamamura S, Malik S, Spiegelman BM and Roeder RG. Coordination of p300-mediated chromatin remodeling and TRAP/mediator function through coactivator PGC-1α. Mol Cell 2003, 12: 1137-1149. (Pubitemid 37487924)
-
(2003)
Molecular Cell
, vol.12
, Issue.5
, pp. 1137-1149
-
-
Wallberg, A.E.1
Yamamura, S.2
Malik, S.3
Spiegelman, B.M.4
Roeder, R.G.5
-
4
-
-
48349108293
-
Genome-wide coactivation analysis of PGC-1αidentifies BAF60a as a regulator of hepatic lipid metabolism
-
Li S, Liu C, Li N, Hao T, Han T, Hill DE and Vidal M, et al. Genome-wide coactivation analysis of PGC-1αidentifies BAF60a as a regulator of hepatic lipid metabolism. Cell Metab 2008, 8:105-117.
-
(2008)
Cell Metab
, vol.8
, pp. 105-117
-
-
Li, S.1
Liu, C.2
Li, N.3
Hao, T.4
Han, T.5
Hill, D.E.6
Vidal, M.7
-
5
-
-
0033638283
-
Direct coupling of transcription and mRNA processing through the thermogenic coactivator PGC-1
-
Monsalve M, Wu Z, Adelmant G, Puigserver P, Fan M and Spiegelman BM. Direct coupling of transcription and mRNA processing through the thermogenic coactivator PGC-1. Mol Cell 2000, 6: 307-316.
-
(2000)
Mol Cell
, vol.6
, pp. 307-316
-
-
Monsalve, M.1
Wu, Z.2
Adelmant, G.3
Puigserver, P.4
Fan, M.5
Spiegelman, B.M.6
-
6
-
-
0037147304
-
Glucocorticoid signaling is perturbed by the atypical orphan receptor and corepressor SHP
-
DOI 10.1074/jbc.M205641200
-
Borgius LJ, Steffensen KR, Gustafsson JA and Treuter E. Glucocorticoid signaling is perturbed by the atypical orphan receptor and core pressor SHP. J Biol Chem 2002, 277: 49761-49766. (Pubitemid 36014422)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.51
, pp. 49761-49766
-
-
Borgius, L.J.1
Steffensen, K.R.2
Gustafsson, J.-A.3
Treuter, E.4
-
7
-
-
0042232315
-
PGC-1β in the regulation of hepatic glucose and energy metabolism
-
DOI 10.1074/jbc.M303643200
-
Lin J, Tarr PT, Yang R, Rhee J, Puigserver P, Newgard CB and Spiegelman BM. PGC-1βin the regulation of hepatic glucose and energy metabolism. J Biol Chem 2003, 278: 30843-30848. (Pubitemid 36994593)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.33
, pp. 30843-30848
-
-
Lin, J.1
Tarr, P.T.2
Yang, R.3
Rhee, J.4
Puigserver, P.5
Newgard, C.B.6
Spiegelman, B.M.7
-
8
-
-
0035016566
-
PGC-1-related coactivator, a novel, serum-inducible coactivator of nuclear respiratory factor 1-dependent transcription in mammalian cells
-
DOI 10.1128/MCB.21.11.3738-3749.2001
-
Andersson U and Scarpulla RC. Pgc-1-related coactivator, a novel, serum-inducible coactivator of nuclear respiratory factor 1-dependent transcription in mammalian cells. Mol Cell Biol 2001, 21: 3738-3749. (Pubitemid 32466987)
-
(2001)
Molecular and Cellular Biology
, vol.21
, Issue.11
, pp. 3738-3749
-
-
Andersson, U.1
Scarpulla, R.C.2
-
9
-
-
75649131899
-
The drosophila PGC-1 homologue spargel coordinates mitochondrial activity to insulin signaling
-
Tiefenböck SK, Baltzer C, Egli NA and Frei C. The Drosophila PGC-1 homologue Spargel coordinates mitochondrial activity to insulin signaling. EMBO J 2010, 29: 171-183.
-
(2010)
EMBO J
, vol.29
, pp. 171-183
-
-
Tiefenböck, S.K.1
Baltzer, C.2
Egli, N.A.3
Frei, C.4
-
10
-
-
0033538473
-
Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1
-
DOI 10.1016/S0092-8674(00)80611-X
-
Wu Z, Puigserver P, Andersson U, Zhang C, Adelmant G, Mootha V and Troy A, et al. Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1. Cell 1999, 98: 115-124. (Pubitemid 29331201)
-
(1999)
Cell
, vol.98
, Issue.1
, pp. 115-124
-
-
Wu, Z.1
Puigserver, P.2
Andersson, U.3
Zhang, C.4
Adelmant, G.5
Mootha, V.6
Troy, A.7
Cinti, S.8
Lowell, B.9
Scarpulla, R.C.10
Spiegelman, B.M.11
-
11
-
-
0032715653
-
Human peroxi-some proliferator activated receptor g coactivator 1 (PPARGC1) gene: Cdna sequence, genomic organization, chromosomal localization, and tissue expression
-
Esterbauer H, Oberkofler H, Krempler F and Patsch W. Human peroxi-some proliferator activated receptor g coactivator 1 (PPARGC1) gene: cDNA sequence, genomic organization, chromosomal localization, and tissue expression. Genomics 1999, 62: 98-102.
-
(1999)
Genomics
, vol.62
, pp. 98-102
-
-
Esterbauer, H.1
Oberkofler, H.2
Krempler, F.3
Patsch, W.4
-
12
-
-
0034116143
-
A tissue-specific coactivator of steroid receptors, identified in a functional genetic screen
-
DOI 10.1128/MCB.20.7.2411-2422.2000
-
Knutti D, Kaul A and Kralli A. A tissue-specific coactivator of steroid receptors, identified in a functional genetic screen. Mol Cell Biol 2000, 20: 2411-2422. (Pubitemid 30152049)
-
(2000)
Molecular and Cellular Biology
, vol.20
, Issue.7
, pp. 2411-2422
-
-
Knutti, D.1
Kaul, A.2
Kralli, A.3
-
13
-
-
2342477730
-
Errα and Gabpa/b specify PGC-1α-dependent oxidative phosphorylation gene expression that is altered in diabetic muscle
-
DOI 10.1073/pnas.0401401101
-
Mootha VK, Handschin C, Arlow D, Xie X, St Pierre J, Sihag S and Yang W, et al. Errαand Gabpa/b specify PGC-1α-dependent oxidative phosphorylation gene expression that is altered in diabetic muscle. Proc Natl Acad Sci USA 2004, 101: 6570-6575. (Pubitemid 38586015)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.17
, pp. 6570-6575
-
-
Mootha, V.K.1
Handschin, C.2
Arlow, D.3
Xie, X.4
St. Pierre, J.5
Sihag, S.6
Yang, W.7
Altshuler, D.8
Puigserver, P.9
Patterson, N.10
Willy, P.J.11
Schulman, I.G.12
Heyman, R.A.13
Lander, E.S.14
Spiegelman, B.M.15
-
14
-
-
2342592545
-
The estrogen-related receptor α (ERRα) functions in PPARγ coactivator 1α (PGC-1α)-induced mitochondrial biogenesis
-
DOI 10.1073/pnas.0308686101
-
Schreiber SN, Emter R, Hock MB, Knutti D, Cardenas J, Podvinec M and Oakeley EJ, et al. The estrogen-related receptor a (ERRα) functions in PPARγcoactivator 1α(PGC-1α)-induced mitochondrial biogenesis. Proc Natl Acad Sci USA 2004, 101: 6472-6477. (Pubitemid 38585998)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.17
, pp. 6472-6477
-
-
Schreiber, S.N.1
Emter, R.2
Hock, M.B.3
Knutti, D.4
Cardenas, J.5
Podvinec, M.6
Oakeley, E.J.7
Kralli, A.8
-
15
-
-
0037036115
-
Nuclear activators and coactivators in mammalian mitochondrial biogenesis
-
DOI 10.1016/S0167-4781(02)00343-3, PII S0167478102003433
-
Scarpulla RC. Nuclear activators and coactivators in mammalian mitochondrial biogenesis. Biochim Biophys Acta 2002, 1576: 1-14. (Pubitemid 34597079)
-
(2002)
Biochimica et Biophysica Acta - Gene Structure and Expression
, vol.1576
, Issue.1-2
, pp. 1-14
-
-
Scarpulla, R.C.1
-
16
-
-
0037029049
-
Transcriptional activators and coactivators in the nuclear control of mitochondrial function in mammalian cells
-
DOI 10.1016/S0378-1119(01)00809-5, PII S0378111901008095
-
Scarpulla RC. Transcriptional activators and coactivators in the nuclear control of mitochondrial function in mammalian cells. Gene 2002, 286: 81-89. (Pubitemid 34273864)
-
(2002)
Gene
, vol.286
, Issue.1
, pp. 81-89
-
-
Scarpulla, R.C.1
-
17
-
-
0031930319
-
Mitochondrial transcription factor A is necessary for mtDNA maintenance and embryogenesis in mice
-
DOI 10.1038/ng0398-231
-
Larsson NG, Wang J, Wilhelmsson H, Oldfors A, Rustin P, Lewandoski M and Barsh GS, et al. Mitochondrial transcription factor A is necessary for mtDNA maintenance and embryogenesis in mice. Nat Genet 1998, 18: 231-236. (Pubitemid 28117260)
-
(1998)
Nature Genetics
, vol.18
, Issue.3
, pp. 231-236
-
-
Larsson, N.-G.1
Wang, J.2
Wilhelmsson, H.3
Oldfors, A.4
Rustin, P.5
Lewandoski, M.6
Barsh, G.S.7
Clayton, D.A.8
-
18
-
-
24144463983
-
Metabolic control through the PGC-1 family of transcription coactivators
-
DOI 10.1016/j.cmet.2005.05.004, PII S1550413105001427
-
Lin J, Handschin C and Spiegelman BM. Metabolic control through the PGC-1 family of transcription coactivators. Cell Metab 2005, 1: 361-370. (Pubitemid 43960626)
-
(2005)
Cell Metabolism
, vol.1
, Issue.6
, pp. 361-370
-
-
Lin, J.1
Handschin, C.2
Spiegelman, B.M.3
-
20
-
-
33744905787
-
PGC-1α: A potent transcriptional cofactor involved in the pathogenesis of type 2 diabetes
-
DOI 10.1007/s00125-006-0268-6
-
Soyal S, Krempler F, Oberkofler H and Patsch W. PGC-1α: a potent transcriptional cofactor involved in the pathogenesis of type 2 diabetes. Diabetologia 2006, 49: 1477-1488. (Pubitemid 43848083)
-
(2006)
Diabetologia
, vol.49
, Issue.7
, pp. 1477-1488
-
-
Soyal, S.1
Krempler, F.2
Oberkofler, H.3
Patsch, W.4
-
21
-
-
33750437278
-
Thermoregulatory and metabolic defects in Huntington's disease transgenic mice implicate PGC-1α in Huntington's disease neurodegeneration
-
DOI 10.1016/j.cmet.2006.10.004, PII S1550413106003329
-
Weydt P, Pineda VV, Torrence AE, Libby RT, Satterfield TF, Lazarowski ER and Gilbert ML, et al. Thermoregulatory and metabolic defects in Huntington's disease transgenic mice implicate PGC-1αin Huntington's disease neurodegeneration. Cell Metab 2006, 4: 349-362. (Pubitemid 44645069)
-
(2006)
Cell Metabolism
, vol.4
, Issue.5
, pp. 349-362
-
-
Weydt, P.1
Pineda, V.V.2
Torrence, A.E.3
Libby, R.T.4
Satterfield, T.F.5
Lazarowski, EduardoR.6
Gilbert, M.L.7
Morton, G.J.8
Bammler, T.K.9
Strand, A.D.10
Cui, L.11
Beyer, R.P.12
Easley, C.N.13
Smith, A.C.14
Krainc, D.15
Luquet, S.16
Sweet, IanR.17
Schwartz, M.W.18
La Spada, A.R.19
-
22
-
-
33749999530
-
Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators
-
DOI 10.1016/j.cell.2006.09.024, PII S0092867406012281
-
St-Pierre J, Drori S, Uldry M, Silvaggi JM, Rhee J, Jäger S and Handschin C, et al. Suppression of reactive oxygen species and neurode-generation by the PGC-1 transcriptional coactivators. Cell 2006, 127: 397-408. (Pubitemid 44572377)
-
(2006)
Cell
, vol.127
, Issue.2
, pp. 397-408
-
-
St-Pierre, J.1
Drori, S.2
Uldry, M.3
Silvaggi, J.M.4
Rhee, J.5
Jager, S.6
Handschin, C.7
Zheng, K.8
Lin, J.9
Yang, W.10
Simon, D.K.11
Bachoo, R.12
Spiegelman, B.M.13
-
23
-
-
33947577655
-
Localization of the transcriptional coactivator PGC-1α to GABAergic neurons during maturation of the rat brain
-
DOI 10.1002/cne.21211
-
Cowell RM, Blake KR and Russell JW. Localization of the transcriptional coactivator PGC-1αto GABAergic neurons during maturation of the rat brain. J Comp Neurol 2007, 502: 1-18. (Pubitemid 46481928)
-
(2007)
Journal of Comparative Neurology
, vol.502
, Issue.1
, pp. 1-18
-
-
Cowell, R.M.1
Blake, K.R.2
Russell, J.W.3
-
24
-
-
0033803048
-
Peroxisome proliferator-activated receptor g coactivator-1 promotes cardiac mitochondrial biogenesis
-
Lehman JJ, Barger PM, Kovacs A, Saffitz JE, Medeiros DM and Kelly DP. Peroxisome proliferator-activated receptor g coactivator-1 promotes cardiac mitochondrial biogenesis. J Clin Invest 2000, 106: 847-856.
-
(2000)
J Clin Invest
, vol.106
, pp. 847-856
-
-
Lehman, J.J.1
Barger, P.M.2
Kovacs, A.3
Saffitz, J.E.4
Medeiros, D.M.5
Kelly, D.P.6
-
25
-
-
47549114849
-
Transcriptional coactivators PGC-lα and PGC-lβ control overlapping programs required for perinatal maturation of the heart
-
DOI 10.1101/gad.1661708
-
Lai L, Leone TC, Zechner C, Schaeffer PJ, Kelly SM, Flanagan DP and Medeiros DM, et al. Transcriptional coactivators PGC-1αand PGC-1βcontrol overlapping programs required for perinatal maturation of the heart. Genes Dev 2008, 22: 1948-1961. (Pubitemid 352008642)
-
(2008)
Genes and Development
, vol.22
, Issue.14
, pp. 1948-1961
-
-
Lai, L.1
Leone, T.C.2
Zechner, C.3
Schaeffer, P.J.4
Kelly, S.M.5
Flanagan, D.P.6
Medeiros, D.M.7
Kovacs, A.8
Kelly, D.P.9
-
26
-
-
34247590356
-
PGC-1β controls mitochondrial metabolism to modulate circadian activity, adaptive thermogenesis, and hepatic steatosis
-
DOI 10.1073/pnas.0611623104
-
Sonoda J, Mehl IR, Chong LW, Nofsinger RR and Evans RM. PGC-1βcontrols mitochondrial metabolism to modulate circadian activity, adaptive thermogenesis, and hepatic steatosis. Proc Natl Acad Sci USA 2007, 104: 5223-5228. (Pubitemid 47186203)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.12
, pp. 5223-5228
-
-
Sonoda, J.1
Mehl, I.R.2
Chong, L.-W.3
Nofsinger, R.R.4
Evans, R.M.5
-
27
-
-
33646124709
-
Complementary action of the PGC-1 coactivators in mitochondrial biogenesis and brown fat differentiation
-
Uldry M, Yang W, St-Pierre J, Lin J, Seale P and Spiegelman BM. Complementary action of the PGC-1 coactivators in mitochondrial biogenesis and brown fat differentiation. Cell Metab 2006, 3: 333-341.
-
(2006)
Cell Metab
, vol.3
, pp. 333-341
-
-
Uldry, M.1
Yang, W.2
St-Pierre, J.3
Lin, J.4
Seale, P.5
Spiegelman, B.M.6
-
28
-
-
33751022208
-
Ablation of PGC-1βresults in defective mitochondrial activity, thermogenesis, hepatic function, and cardiac performance
-
Lelliott CJ, Medina-Gomez G, Petrovic N, Kis A, Feldmann HM, Bjursell M and Parker N, et al. Ablation of PGC-1βresults in defective mitochondrial activity, thermogenesis, hepatic function, and cardiac performance. PLoS Biol 2006, 4: e369.
-
(2006)
PLoS Biol
, vol.4
-
-
Lelliott, C.J.1
Medina-Gomez, G.2
Petrovic, N.3
Kis, A.4
Feldmann, H.M.5
Bjursell, M.6
Parker, N.7
-
29
-
-
0037102256
-
Transcriptional coactivator PGC-1αdrives the formation of slow-twitch muscle fibres
-
Lin J, Wu H, Tarr PT, Zhang CY, Wu Z, Boss O and Michael LF, et al. Transcriptional coactivator PGC-1αdrives the formation of slow-twitch muscle fibres. Nature 2002, 418: 797-801.
-
(2002)
Nature
, vol.418
, pp. 797-801
-
-
Lin, J.1
Wu, H.2
Tarr, P.T.3
Zhang, C.Y.4
Wu, Z.5
Boss, O.6
Michael, L.F.7
-
30
-
-
34347272966
-
Overexpression of PGC-1αleads to muscle atrophy with depletion of ATP
-
Miura S, Tomitsuka E, Kamei Y, Yamazaki T, Kai Y, Tamura M and Kita K, et al. Overexpression of PGC-1αleads to muscle atrophy with depletion of ATP. Am J Pathol 2006, 169: 1129-1139.
-
(2006)
Am J Pathol
, vol.169
, pp. 1129-1139
-
-
Miura, S.1
Tomitsuka, E.2
Kamei, Y.3
Yamazaki, T.4
Kai, Y.5
Tamura, M.6
Kita, K.7
-
31
-
-
33845674997
-
The transcriptional coactivator PGC-1βdrives the formation of oxidative type IIX fibers in skeletal muscle
-
DOI 10.1016/j.cmet.2006.12.003, PII S1550413106004001
-
Arany Z, Lebrasseur N, Morris C, Smith E, Yang W, Ma Y and Chin S, et al. The transcriptional coactivator PGC-1βdrives the formation of oxidative type IIX fibers in skeletal muscle. Cell Metab 2007, 5: 35-46. (Pubitemid 44939399)
-
(2007)
Cell Metabolism
, vol.5
, Issue.1
, pp. 35-46
-
-
Arany, Z.1
Lebrasseur, N.2
Morris, C.3
Smith, E.4
Yang, W.5
Ma, Y.6
Chin, S.7
Spiegelman, B.M.8
-
32
-
-
0035855858
-
Control of hepatic gluconeogenesis through the transcriptional coaotivator PGC-1
-
DOI 10.1038/35093050
-
Yoon JC, Puigserver P, Chen G, Donovan J, Wu Z, Rhee J and Adelmant G, et al. Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1. Nature 2001, 413: 131-138. (Pubitemid 32867868)
-
(2001)
Nature
, vol.413
, Issue.6852
, pp. 131-138
-
-
Yoon, J.C.1
Puigserver, P.2
Chen, G.3
Donovan, J.4
Wu, Z.5
Rhee, J.6
Adelmant, G.7
Stafford, J.8
Kahn, C.R.9
Granner, D.K.10
Newgard, C.B.11
Spiegelman, B.M.12
-
33
-
-
64749096339
-
Regulation of homocysteine homeostasis through the transcriptional coactivator PGC-1α
-
Li S, Arning E, Liu C, Vitvitsky V, Hernandez C, Banerjee R and Bottiglieri T, et al. Regulation of homocysteine homeostasis through the transcriptional coactivator PGC-1α. Am J Physiol Endocrinol Metab 2009, 296: E543-E548.
-
(2009)
Am J Physiol Endocrinol Metab
, vol.296
-
-
Li, S.1
Arning, E.2
Liu, C.3
Vitvitsky, V.4
Hernandez, C.5
Banerjee, R.6
Bottiglieri, T.7
-
34
-
-
34249275727
-
Transcriptional coactivator PGC-1α integrates the mammalian clock and energy metabolism
-
DOI 10.1038/nature05767, PII NATURE05767
-
Liu C, Li S, Liu T, Borjigin J and Lin JD. Transcriptional coactivator PGC-1αintegrates the mammalian clock and energy metabolism. Nature 2007, 447: 477-481. (Pubitemid 46816732)
-
(2007)
Nature
, vol.447
, Issue.7143
, pp. 477-481
-
-
Liu, C.1
Li, S.2
Liu, T.3
Borjigin, J.4
Lin, J.D.5
-
35
-
-
19944430411
-
Hyperlipidemic effects of dietary saturated fats mediated through PGC-1β coactivation of SREBP
-
DOI 10.1016/j.cell.2004.11.043, PII S009286740401147X
-
Lin J, Yang R, Tarr PT, Wu PH, Handschin C, Li S and Yang W, et al. Hyperlipidemic effects of dietary saturated fats mediated through PGC-1βcoactivation of SREBP. Cell 2005, 120: 261-273. (Pubitemid 40174768)
-
(2005)
Cell
, vol.120
, Issue.2
, pp. 261-273
-
-
Lin, J.1
Yang, R.2
Tarr, P.T.3
Wu, P.-H.4
Handschin, C.5
Li, S.6
Yang, W.7
Pei, L.8
Uldry, M.9
Tontonoz, P.10
Newgard, C.B.11
Spiegelman, B.M.12
-
36
-
-
77957674906
-
Regulation of hepatic ApoC3 expression by PGC-1βmediates hypolipidemic effect of nicotinic acid
-
Hernandez C, Molusky M, Li Y, Li S and Lin JD. Regulation of hepatic ApoC3 expression by PGC-1βmediates hypolipidemic effect of nicotinic acid. Cell Metab 2010, 12: 411-419.
-
(2010)
Cell Metab
, vol.12
, pp. 411-419
-
-
Hernandez, C.1
Molusky, M.2
Li, Y.3
Li, S.4
Lin, J.D.5
-
37
-
-
0038686576
-
Suppression of β cell energy metabolism and insulin release by PGC-1α
-
DOI 10.1016/S1534-5807(03)00170-9, PII S1534580703001709
-
Yoon JC, Xu G, Deeney JT, Yang SN, Rhee J, Puigserver P and Levens AR, et al. Suppression of b cell energy metabolism and insulin release by PGC-1α. Dev Cell 2003, 5: 73-83. (Pubitemid 36827343)
-
(2003)
Developmental Cell
, vol.5
, Issue.1
, pp. 73-83
-
-
Yoon, J.C.1
Xu, G.2
Deeney, J.T.3
Yang, S.-N.4
Rhee, J.5
Puigserver, P.6
Levens, A.R.7
Yang, R.8
Zhang, C.-Y.9
Lowell, B.B.10
Berggren, P.-O.11
Newgard, C.B.12
Bonner-Weir, S.13
Weir, G.14
Spiegelman, B.M.15
-
38
-
-
60549086405
-
Transcriptional coactivator peroxisome proliferator-activated receptor (PPAR) g coactivator-1βis involved in the regulation of glucose-stimulated insulin secretion in INS-1E cells
-
Oberkofler H, Hafner M, Felder T, Krempler F and Patsch W. Transcriptional coactivator peroxisome proliferator-activated receptor (PPAR) g coactivator-1βis involved in the regulation of glucose-stimulated insulin secretion in INS-1E cells. J Mol Med 2009, 87: 299-306.
-
(2009)
J Mol Med
, vol.87
, pp. 299-306
-
-
Oberkofler, H.1
Hafner, M.2
Felder, T.3
Krempler, F.4
Patsch, W.5
-
39
-
-
5344252327
-
Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1α null mice
-
DOI 10.1016/j.cell.2004.09.013, PII S0092867404008864
-
Lin J, Wu PH, Tarr PT, Lindenberg KS, St-Pierre J, Zhang CY and Mootha VK, et al. Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1αnull mice. Cell 2004, 119: 121-135. (Pubitemid 39349325)
-
(2004)
Cell
, vol.119
, Issue.1
, pp. 121-135
-
-
Lin, J.1
Wu, P.-H.2
Tarr, P.T.3
Lindenberg, K.S.4
St-Pierre, J.5
Zhang, C.-Y.6
Mootha, V.K.7
Jager, S.8
Vianna, C.R.9
Reznick, R.M.10
Cui, L.11
Manieri, M.12
Donovan, M.X.13
Wu, Z.14
Cooper, M.P.15
Fan, M.C.16
Rohas, L.M.17
Zavacki, A.M.18
Cinti, S.19
Shulman, G.I.20
Lowell, B.B.21
Krainc, D.22
Spiegelman, B.M.23
more..
-
40
-
-
21144446106
-
PGC-1αdeficiency causes multisystem energy metabolic derangements: Muscle dysfunction, abnormal weight control and hepatic steatosis
-
Leone TC, Lehman JJ, Finck BN, Schaeffer PJ, Wende AR, Boudina S and Courtois M, et al. PGC-1αdeficiency causes multisystem energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosis. PLoS Biol 2005, 3: e101.
-
(2005)
PLoS Biol
, vol.3
-
-
Leone, T.C.1
Lehman, J.J.2
Finck, B.N.3
Schaeffer, P.J.4
Wende, A.R.5
Boudina, S.6
Courtois, M.7
-
41
-
-
36048931015
-
Abnormal glucose homeostasis in skeletal muscle-specific PGC-1α knockout mice reveals skeletal muscle-pancreatic β cell crosstalk
-
DOI 10.1172/JCI31785
-
Handschin C, Choi CS, Chin S, Kim S, Kawamori D, Kurpad AJ and Neubauer N, et al. Abnormal glucose homeostasis in skeletal muscle-specific PGC-1αknockout mice reveals skeletal muscle-pancreatic beta cell crosstalk. J Clin Invest 2007, 117: 3463-3474. (Pubitemid 350097002)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.11
, pp. 3463-3474
-
-
Handschin, C.1
Cheol, S.C.2
Chin, S.3
Kim, S.4
Kawamori, D.5
Kurpad, A.J.6
Neubauer, N.7
Hu, J.8
Mootha, V.K.9
Kim, Y.-B.10
Kulkarni, R.N.11
Shulman, G.I.12
Spiegelman, B.M.13
-
42
-
-
12144286554
-
Cardiac-Specific Induction of the Transcriptional Coactivator Peroxisome Proliferator-Activated Receptor γ Coactivator-1α Promotes Mitochondrial Biogenesis and Reversible Cardiomyopathy in a Developmental Stage-Dependent Manner
-
DOI 10.1161/01.RES.0000117088.36577.EB
-
Russell LK, Mansfield CM, Lehman JJ, Kovacs A, Courtois M, Saffitz JE and Medeiros DM, et al. Cardiac-specific induction of the transcriptional coactivator PGC-1αpromotes mitochondrial biogenesis and reversible cardiomyopathy in a developmental stage-dependent manner. Circ Res 2004, 94: 525-533. (Pubitemid 38326288)
-
(2004)
Circulation Research
, vol.94
, Issue.4
, pp. 525-533
-
-
Russell, L.K.1
Mansfield, C.M.2
Lehman, J.J.3
Kovacs, A.4
Courtois, M.5
Saffitz, J.E.6
Medeiros, D.M.7
Valencik, M.L.8
McDonald, J.A.9
Kelly, D.P.10
-
43
-
-
33751400561
-
Hypomorphic mutation of PGC-1β causes mitochondrial dysfunction and liver insulin resistance
-
DOI 10.1016/j.cmet.2006.11.003, PII S1550413106003652
-
Vianna CR, Huntgeburth M, Coppari R, Choi CS, Lin J, Krauss S and Barbatelli G, et al. Hypomorphic mutation of PGC-1βcauses mitochondrial dysfunction and liver insulin resistance. Cell Metab 2006, 4: 453-464. (Pubitemid 44817352)
-
(2006)
Cell Metabolism
, vol.4
, Issue.6
, pp. 453-464
-
-
Vianna, C.R.1
Huntgeburth, M.2
Coppari, R.3
Choi, C.S.4
Lin, J.5
Krauss, S.6
Barbatelli, G.7
Tzameli, I.8
Kim, Y.-B.9
Cinti, S.10
Shulman, G.I.11
Spiegelman, BruceM.12
Lowell, B.B.13
-
44
-
-
33749042331
-
Transcriptional repression of PGC-1α by mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration
-
DOI 10.1016/j.cell.2006.09.015, PII S0092867406012050
-
Cui L, Jeong H, Borovecki F, Parkhurst CN, Tanese N and Krainc D. Transcriptional repression of PGC-1αby mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration. Cell 2006, 127: 59-69. (Pubitemid 44466642)
-
(2006)
Cell
, vol.127
, Issue.1
, pp. 59-69
-
-
Cui, L.1
Jeong, H.2
Borovecki, F.3
Parkhurst, C.N.4
Tanese, N.5
Krainc, D.6
-
45
-
-
14644425217
-
Mitochondrial energy metabolism in heart failure: A question of balance
-
DOI 10.1172/JCI200524405
-
Huss JM and Kelly DP. Mitochondrial energy metabolism in heart failure: a question of balance. J Clin Invest 2005, 115: 547-555. (Pubitemid 40322224)
-
(2005)
Journal of Clinical Investigation
, vol.115
, Issue.3
, pp. 547-555
-
-
Huss, J.M.1
Kelly, D.P.2
-
46
-
-
22144434964
-
Transcriptional coactivator PGC-1α controls the energy state and contractile function of cardiac muscle
-
DOI 10.1016/j.cmet.2005.03.002, PII S1550413105000811
-
Arany Z, He H, Lin J, Hoyer K, Handschin C, Toka O and Ahmad F, et al. Transcriptional coactivator PGC-1αcontrols the energy state and contractile function of cardiac muscle. Cell Metab 2005, 1: 259-271. (Pubitemid 43960608)
-
(2005)
Cell Metabolism
, vol.1
, Issue.4
, pp. 259-271
-
-
Arany, Z.1
He, H.2
Lin, J.3
Hoyer, K.4
Handschin, C.5
Toka, O.6
Ahmad, F.7
Matsui, T.8
Chin, S.9
Wu, P.-H.10
Rybkin, I.I.11
Shelton, J.M.12
Manieri, M.13
Cinti, S.14
Schoen, F.J.15
Bassel-Duby, R.16
Rosenzweig, A.17
Ingwall, J.S.18
Spiegelman, B.M.19
-
47
-
-
0037127204
-
Peroxisome proliferator-activated receptor γ coactivator 1β (PGC-1β), a novel PGC-1-related transcription coactivator associated with host cell factor
-
DOI 10.1074/jbc.C100631200
-
Lin J, Puigserver P, Donovan J, Tarr P and Spiegelman BM. Peroxisome proliferator-activated receptor gamma coactivator 1β(PGC-1β), a novel PGC-1-related transcription coactivator associated with host cell factor. J Biol Chem 2002, 277: 1645-1648. (Pubitemid 34968733)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.3
, pp. 1645-1648
-
-
Lin, J.1
Puigserver, P.2
Donovan, J.3
Tarr, P.4
Spiegelman, B.M.5
-
48
-
-
0036903174
-
Adaptations of skeletal muscle to exercise: Rapid increase in the transcriptional coactivator PGC-1
-
DOI 10.1096/fj.02-0367com
-
Baar K, Wende AR, Jones TE, Marison M, Nolte LA, Chen M and Kelly DP, et al. Adaptations of skeletal muscle to exercise: rapid increase in the transcriptional coactivator PGC-1. FASEB J 2002, 16: 1879-1886. (Pubitemid 35462607)
-
(2002)
FASEB Journal
, vol.16
, Issue.14
, pp. 1879-1886
-
-
Baar, K.1
Wende, A.R.2
Jones, T.E.3
Marison, M.4
Nolte, L.A.5
Chen, M.6
Kelly, D.P.7
Holloszy, J.O.8
-
49
-
-
0034596268
-
CDNA cloning and mRNA analysis of PGC-1 in epitrochlearis muscle in swimming-exercised rats
-
DOI 10.1006/bbrc.2000.3134
-
Goto M, Terada S, Kato M, Katoh M, Yokozeki T, Tabata I and Shimokawa T. cDNA cloning and mRNA analysis of PGC-1 in epitrochlearis muscle in swimming-exercised rats. Biochem Biophys Res Commun 2000, 274: 350-354. (Pubitemid 30614322)
-
(2000)
Biochemical and Biophysical Research Communications
, vol.274
, Issue.2
, pp. 350-354
-
-
Goto, M.1
Terada, S.2
Kato, M.3
Katoh, M.4
Yokozeki, T.5
Tabata, I.6
Shimokawa, T.7
-
50
-
-
0347993714
-
PGC-1α mRNA expression is influenced by metabolic perturbation in exercising human skeletal muscle
-
DOI 10.1152/japplphysiol.00765.2003
-
Norrbom J, Sundberg CJ, Ameln H, Kraus WE, Jansson E and Gustafsson T. PGC-1αmRNA expression is influenced by metabolic perturbation in exercising human skeletal muscle. J Appl Physiol 2004, 96: 189-194. (Pubitemid 38032000)
-
(2004)
Journal of Applied Physiology
, vol.96
, Issue.1
, pp. 189-194
-
-
Norrbom, J.1
Sundberg, C.J.2
Ameln, H.3
Kraus, W.E.4
Jansson, E.5
Gustafsson, T.6
-
51
-
-
21244477127
-
Exercise stimulates Pgc-1α transcription in skeletal muscle through activation of the p38 MAPK pathway
-
DOI 10.1074/jbc.M408862200
-
Akimoto T, Pohnert SC, Li P, Zhang M, Gumbs C, Rosenberg PB and Williams RS, et al. Exercise stimulates PGC-1αtranscription in skeletal muscle through activation of the p38 MAPK pathway. J Biol Chem 2005, 280: 19587-19593. (Pubitemid 41379480)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.20
, pp. 19587-19593
-
-
Akimoto, T.1
Pohnert, S.C.2
Li, P.3
Zhang, M.4
Gumbs, C.5
Rosenberg, P.B.6
Williams, R.S.7
Yan, Z.8
-
52
-
-
0037066459
-
Regulation of mitochondrial biogenesis in skeletal muscle by caMK
-
DOI 10.1126/science.1071163
-
Wu H, Kanatous SB, Thurmond FA, Gallardo T, Isotani E, Bassel-Duby R and Williams RS. Regulation of mitochondrial biogenesis in skeletal muscle by CaMK. Science 2002, 296: 349-352. (Pubitemid 34303690)
-
(2002)
Science
, vol.296
, Issue.5566
, pp. 349-352
-
-
Wu, H.1
Kanatous, S.B.2
Thurmond, F.A.3
Gallardo, T.4
Isotani, E.5
Bassel-Duby, R.6
Williams, R.S.7
-
53
-
-
0037058977
-
AMP kinase is required for mitochondrial biogenesis in skeletal muscle in response to chronic energy deprivation
-
DOI 10.1073/pnas.252625599
-
Zong H, Ren JM, Young LH, Pypaert M, Mu J, Birnbaum MJ and Shulman GI. AMP kinase is required for mitochondrial biogenesis in skeletal muscle in response to chronic energy deprivation. Proc Natl Acad Sci USA 2002, 99: 15983-15987. (Pubitemid 35462735)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.25
, pp. 15983-15987
-
-
Zong, H.1
Ren, J.M.2
Young, L.H.3
Pypaert, M.4
Mu, J.5
Birnbaum, M.J.6
Shulman, G.I.7
-
54
-
-
77952892253
-
PGC-1α-mediated adaptations in skeletal muscle
-
Olesen J, Kiilerich K and Pilegaard H. PGC-1α-mediated adaptations in skeletal muscle. Pflugers Arch 2010, 460: 153-162.
-
(2010)
Pflugers Arch
, vol.460
, pp. 153-162
-
-
Olesen, J.1
Kiilerich, K.2
Pilegaard, H.3
-
55
-
-
33749242948
-
PGC-1α and PGC-1β have both similar and distinct effects on myofiber switching toward an oxidative phenotype
-
DOI 10.1152/ajpendo.00591.2005
-
Mortensen OH, Frandsen L, Schjerling P, Nishimura E and Grunnet N. PGC-1αand PGC-1βhave both similar and distinct effects on myofiber switching toward an oxidative phenotype. Am J Physiol Endocrinol Metab 2006, 291: E807-E816. (Pubitemid 44484924)
-
(2006)
American Journal of Physiology - Endocrinology and Metabolism
, vol.291
, Issue.4
-
-
Mortensen, O.H.1
Frandsen, L.2
Schjerling, P.3
Nishimura, E.4
Grunnet, N.5
-
56
-
-
33747507302
-
PGC-1β down-regulation is associated with reduced ERRα activity and MCAD expression in skeletal muscle of senescence-accelerated mice
-
Rodríguez-Calvo R, JovéM, Coll T, Camins A, Sánchez RM, Alegret M and Merlos M, et al. PGC-1βdown-regulation is associated with reduced ERRα activity and MCAD expression in skeletal muscle of senescence-accelerated mice. J Gerontol A Biol Sci Med Sci 2006, 61: 773-780. (Pubitemid 44260159)
-
(2006)
Journals of Gerontology - Series A Biological Sciences and Medical Sciences
, vol.61
, Issue.8
, pp. 773-780
-
-
Rodriguez-Calvo, R.1
Jove, M.2
Coll, T.3
Camins, A.4
Sanchez, R.M.5
Alegret, M.6
Merlos, M.7
Pallas, M.8
Laguna, J.C.9
Vazquez-Carrera, M.10
-
57
-
-
2442701392
-
PGC-1 promotes insulin resistance in liver through PPAR-α-dependent induction of TRB-3
-
DOI 10.1038/nm1044
-
Koo SH, Satoh H, Herzig S, Lee CH, Hedrick S, Kulkarni R and Evans RM, et al. PGC-1 promotes insulin resistance in liver through PPAR-α-dependent induction of TRB-3. Nat Med 2004, 10: 530-534. (Pubitemid 38667913)
-
(2004)
Nature Medicine
, vol.10
, Issue.5
, pp. 530-534
-
-
Koo, S.-H.1
Satoh, H.2
Herzig, S.3
Lee, C.-H.4
Hedrick, S.5
Kulkarni, R.6
Evans, R.M.7
Olefsky, J.8
Montminy, M.9
-
58
-
-
32444451567
-
Coactivation of Foxa2 through PGC-1βpromotes liver fatty acid oxidation and triglyceride/VLDL secretion
-
Wolfrum C and Stoffel M. Coactivation of Foxa2 through PGC-1βpromotes liver fatty acid oxidation and triglyceride/VLDL secretion. Cell Metab 2006, 3: 99-110.
-
(2006)
Cell Metab
, vol.3
, pp. 99-110
-
-
Wolfrum, C.1
Stoffel, M.2
-
59
-
-
60649109153
-
The role of peroxisome proliferator-activated receptor gamma coactivator-1 beta in the pathogenesis of fructose-induced insulin resistance
-
Nagai Y, Yonemitsu S, Erion DM, Iwasaki T, Stark R, Weismann D and Dong J, et al. The role of peroxisome proliferator-activated receptor gamma coactivator-1 beta in the pathogenesis of fructose-induced insulin resistance. Cell Metab 2009, 9: 252-264.
-
(2009)
Cell Metab
, vol.9
, pp. 252-264
-
-
Nagai, Y.1
Yonemitsu, S.2
Erion, D.M.3
Iwasaki, T.4
Stark, R.5
Weismann, D.6
Dong, J.7
-
60
-
-
0345548705
-
Peroxisome proliferator-activated receptor γ coactivator-1- dependent uncoupling protein-2 expression in pancreatic islets of rats: A novel pathway for neural control of insulin secretion
-
DOI 10.1007/s00125-003-1222-5
-
De Souza CT, Gasparetti AL, Pereira-da-Silva M, Araújo EP, Carvalheira JB, Saad MJ and Boschero AC, et al. Peroxisome proliferator- activated receptor gamma coactivator-1-dependent uncoupling protein-2 expression in pancreatic islets of rats: a novel pathway for neural control of insulin secretion. Diabetologia 2003, 46: 1522-1531. (Pubitemid 37518573)
-
(2003)
Diabetologia
, vol.46
, Issue.11
, pp. 1522-1531
-
-
De Souza, C.T.1
Gasparetti, A.L.2
Pereira-da-Silva, M.3
Araujo, E.P.4
Carvalheira, J.B.5
Saad, M.J.A.6
Boschero, A.C.7
Carneiro, E.M.8
Velloso, L.A.9
-
61
-
-
14244266050
-
Free fatty acids increase PGC-1α expression in isolated rat islets
-
DOI 10.1016/j.febslet.2005.01.046
-
Zhang P, Liu C, Zhang C, Zhang Y, Shen P, Zhang J and Zhang CY. Free fatty acids increase PGC-1αexpression in isolated rat islets. FEBS Lett 2005, 579: 1446-1452. (Pubitemid 40289194)
-
(2005)
FEBS Letters
, vol.579
, Issue.6
, pp. 1446-1452
-
-
Zhang, P.1
Liu, C.2
Zhang, C.3
Zhang, Y.4
Shen, P.5
Zhang, J.6
Zhang, C.-Y.7
-
62
-
-
0036950665
-
The forkhead transcription factor Foxo1 links insulin signaling to Pdx1 regulation of pancreatic β cell growth
-
DOI 10.1172/JCI200216857
-
Kitamura T, Nakae J, Kitamura Y, Kido Y, Biggs WH, III, Wright CV and White MF, et al. The forkhead transcription factor Foxo1 links insulin signaling to Pdx1 regulation of pancreatic b cell growth. J Clin Invest 2002, 110: 1839-1847. (Pubitemid 36076491)
-
(2002)
Journal of Clinical Investigation
, vol.110
, Issue.12
, pp. 1839-1847
-
-
Kitamura, T.1
Nakae, J.2
Kitamura, Y.3
Kido, Y.4
Biggs III, W.H.5
Wright, C.V.E.6
White, M.F.7
Arden, K.C.8
Accili, D.9
-
63
-
-
41149172495
-
Epigenetic regulation of PPARGC1A in human type 2 diabetic islets and effect on insulin secretion
-
Ling C, Del Guerra S, Lupi R, Rönn T, Granhall C, Luthman H and Masiello P, et al. Epigenetic regulation of PPARGC1A in human type 2 diabetic islets and effect on insulin secretion. Diabetologia 2008, 51: 615-622.
-
(2008)
Diabetologia
, vol.51
, pp. 615-622
-
-
Ling, C.1
Del Guerra, S.2
Lupi, R.3
Rönn, T.4
Granhall, C.5
Luthman, H.6
Masiello, P.7
-
64
-
-
33744534726
-
GCN5 acetyltransferase complex controls glucose metabolism through transcriptional repression of PGC-1α
-
DOI 10.1016/j.cmet.2006.04.013, PII S1550413106001537
-
Lerin C, Rodgers JT, Kalume DE, Kim SH, Pandey A and Puigserver P. GCN5 acetyltransferase complex controls glucose metabolism through transcriptional repression of PGC-1α. Cell Metab 2006, 3: 429-438. (Pubitemid 43811779)
-
(2006)
Cell Metabolism
, vol.3
, Issue.6
, pp. 429-438
-
-
Lerin, C.1
Rodgers, J.T.2
Kalume, D.E.3
Kim, S.-h.4
Pandey, A.5
Puigserver, P.6
-
65
-
-
14544282413
-
Nutrient control of glucose homeostasis through a complex of PGC-1α and SIRT1
-
DOI 10.1038/nature03354
-
Rodgers JT, Lerin C, Haas W, Gygi SP, Spiegelman BM and Puigserver P. Nutrient control of glucose homeostasis through a complex of PGC-1αand SIRT1. Nature 2005, 434: 113-118. (Pubitemid 40349395)
-
(2005)
Nature
, vol.434
, Issue.7029
, pp. 113-118
-
-
Rodgers, J.T.1
Lerin, C.2
Haas, W.3
Gygi, S.P.4
Spiegelman, B.M.5
Puigserver, P.6
-
66
-
-
18244399631
-
Cytokine Stimulation of Energy Expenditure through p38 MAP Kinase Activation of PPARγ Coactivator-1
-
DOI 10.1016/S1097-2765(01)00390-2
-
Puigserver P, Rhee J, Lin J, Wu Z, Yoon JC, Zhang CY and Krauss S, et al. Cytokine stimulation of energy expenditure through p38 MAP kinase activation of PPARγcoactivator-1. Mol Cell 2001, 8: 971-982. (Pubitemid 34031800)
-
(2001)
Molecular Cell
, vol.8
, Issue.5
, pp. 971-982
-
-
Puigserver, P.1
Rhee, J.2
Lin, J.3
Wu, Z.4
Yoon J.Cliff5
Zhang, C.-Y.6
Krauss, S.7
Mootha, V.K.8
Lowell, B.B.9
Spiegelman, B.M.10
-
67
-
-
34547545892
-
AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1α
-
DOI 10.1073/pnas.0705070104
-
Jager S, Handschin C, St-Pierre J and Spiegelman BM. AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1α. Proc Natl Acad Sci USA 2007, 104: 12017-12022. (Pubitemid 47185622)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.29
, pp. 12017-12022
-
-
Jaer, S.1
Handschin, C.2
St-Pierre, J.3
Spiegelman, B.M.4
-
68
-
-
34250740323
-
Akt/PKB regulates hepatic metabolism by directly inhibiting PGC-1α transcription coactivator
-
DOI 10.1038/nature05861, PII NATURE05861
-
Li X, Monks B, Ge Q and Birnbaum MJ. Akt/PKB regulates hepatic metabolism by directly inhibiting PGC-1αtranscription coactivator. Nature 2007, 447: 1012-1016. (Pubitemid 46975750)
-
(2007)
Nature
, vol.447
, Issue.7147
, pp. 1012-1016
-
-
Li, X.1
Monks, B.2
Ge, Q.3
Birnbaum, M.J.4
-
69
-
-
22344440666
-
Activation of nuclear receptor coactivator PGC-1α by arginine methylation
-
DOI 10.1101/gad.1295005
-
Teyssier C, Ma H, Emter R, Kralli A and Stallcup MR. Activation of nuclear receptor coactivator PGC-1αby arginine methylation. Genes Dev 2005, 19: 1466-1473. (Pubitemid 41003013)
-
(2005)
Genes and Development
, vol.19
, Issue.12
, pp. 1466-1473
-
-
Teyssier, C.1
Ma, H.2
Emter, R.3
Kralli, A.4
Stallcup, M.R.5
-
70
-
-
70350031566
-
SUMOylation attenuates the function of PGC-1α
-
Rytinki MM and Palvimo JJ. SUMOylation attenuates the function of PGC-1α. J Biol Chem 2009, 284: 26184-26193.
-
(2009)
J Biol Chem
, vol.284
, pp. 26184-26193
-
-
Rytinki, M.M.1
Palvimo, J.J.2
-
71
-
-
67349276169
-
+ metabolism and SIRT1 activity
-
+ metabolism and SIRT1 activity. Nature 2009, 458: 1056-1060.
-
(2009)
Nature
, vol.458
, pp. 1056-1060
-
-
Cantó, C.1
Gerhart-Hines, Z.2
Feige, J.N.3
Lagouge, M.4
Noriega, L.5
Milne, J.C.6
Elliott, P.J.7
-
72
-
-
67749124479
-
GCN5-mediated transcriptional control of the metabolic coactivator PGC-1βthrough lysine acetylation
-
Kelly TJ, Lerin C, Haas W, Gygi SP and Puigserver P. GCN5-mediated transcriptional control of the metabolic coactivator PGC-1βthrough lysine acetylation. J Biol Chem 2009, 284: 19945-19952.
-
(2009)
J Biol Chem
, vol.284
, pp. 19945-19952
-
-
Kelly, T.J.1
Lerin, C.2
Haas, W.3
Gygi, S.P.4
Puigserver, P.5
-
73
-
-
0037477855
-
Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1
-
DOI 10.1073/pnas.1032913100
-
Patti ME, Butte AJ, Crunkhorn S, Cusi K, Berria R, Kashyap S and Miyazaki Y, et al. Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: potential role of PGC1 and NRF1. Proc Natl Acad Sci USA 2003, 100: 8466-8471. (Pubitemid 36842568)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.14
, pp. 8466-8471
-
-
Patti, M.E.1
Butte, A.J.2
Crunkhorn, S.3
Cusi, K.4
Berria, R.5
Kashyap, S.6
Miyazaki, Y.7
Kohane, I.8
Costello, M.9
Saccone, R.10
Landaker, E.J.11
Goldfine, A.B.12
Mun, E.13
DeFronzo, R.14
Finlayson, J.15
Kahn, C.R.16
Mandarino, L.J.17
-
74
-
-
0942279549
-
Expression of the thermogenic nuclear hormone receptor coactivator PGC-1α is reduced in the adipose tissue of morbidly obese subjects
-
DOI 10.1038/sj.ijo.0802482
-
Semple RK, Crowley VC, Sewter CP, Laudes M, Christodoulides C, Considine RV and Vidal-Puig A, et al. Expression of the thermogenic nuclear hormone receptor coactivator PGC-1αis reduced in the adipose tissue of morbidly obese subjects. Int J Obes Relat Metab Disord 2004, 28: 176-179. (Pubitemid 38142007)
-
(2004)
International Journal of Obesity
, vol.28
, Issue.1
, pp. 176-179
-
-
Semple, R.K.1
Crowley, V.C.2
Sewter, C.P.3
Laudes, M.4
Christodoulides, C.5
Considine, R.V.6
Vidal-Puig, A.7
O'Rahilly, S.8
-
75
-
-
85047689659
-
Mitochondrial remodeling in adipose tissue associated with obesity and treatment with rosiglitazone
-
DOI 10.1172/JCI200421752
-
Wilson-Fritch L, Nicoloro S, Chouinard M, Lazar MA, Chui PC, Leszyk J and Straubhaar J, et al. Mitochondrial remodeling in adipose tissue associated with obesity and treatment with rosiglitazone. J Clin Invest 2004, 114: 1281-1289. (Pubitemid 40385299)
-
(2004)
Journal of Clinical Investigation
, vol.114
, Issue.9
, pp. 1281-1289
-
-
Wilson-Fritch, L.1
Nicoloro, S.2
Chouinard, M.3
Lazar, M.A.4
Chui, P.C.5
Leszyk, J.6
Straubhaar, J.7
Czech, M.P.8
Corvera, S.9
-
76
-
-
0037326196
-
Peroxisome proliferator-activated receptor-γ coactivator 1α (PGC-1α): Transcriptional coactivator and metabolic regulator
-
DOI 10.1210/er.2002-0012
-
Puigserver P and Spiegelman BM. Peroxisome proliferator-activated receptor-γcoactivator 1α(PGC-1α): transcriptional coactivator and metabolic regulator. Endocr Rev 2003, 24: 78-90. (Pubitemid 36223280)
-
(2003)
Endocrine Reviews
, vol.24
, Issue.1
, pp. 78-90
-
-
Puigserver, P.1
Spiegelman, B.M.2
-
77
-
-
58149401189
-
Paradoxical effects of increased expression of PGC-1αon muscle mitochondrial function and insulin-stimulated muscle glucose metabolism
-
Choi CS, Befroy DE, Codella R, Kim S, Reznick RM, Hwang YJ and Liu ZX, et al. Paradoxical effects of increased expression of PGC-1αon muscle mitochondrial function and insulin-stimulated muscle glucose metabolism. Proc Natl Acad Sci USA 2008, 105: 19926-19931.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 19926-19931
-
-
Choi, C.S.1
Befroy, D.E.2
Codella, R.3
Kim, S.4
Reznick, R.M.5
Hwang, Y.J.6
Liu, Z.X.7
-
78
-
-
0035676129
-
Mutation analysis of peroxisome proliferator-activated receptor-γ coactivator-1 (PGC-1) and relationships of identified amino acid polymorphisms to Type II diabetes mellitus
-
DOI 10.1007/s001250100032
-
Ek J, Andersen G, Urhammer SA, Gaede PH, Drivsholm T, Borch Johnsen K and Hansen T, et al. Mutation analysis of peroxisome proliferator-activated receptor-gamma coactivator-1 (PGC-1) and relationships of identified amino acid polymorphisms to type II diabetes mellitus. Diabetologia 2001, 44: 2220-2226. (Pubitemid 34015475)
-
(2001)
Diabetologia
, vol.44
, Issue.12
, pp. 2220-2226
-
-
Ek, J.1
Andersen, G.2
Urhammer, S.A.3
Gaede, P.H.4
Drivsholm, T.5
Borch-Johnsen, K.6
Hansen, T.7
Pedersen, O.8
-
79
-
-
77954649186
-
PPAR transcriptional activator complex polymorphisms and the promise of individualized therapy for heart failure
-
Mistry NF and Cresci S. PPAR transcriptional activator complex polymorphisms and the promise of individualized therapy for heart failure. Heart Fail Rev 2010, 15: 197-207.
-
(2010)
Heart Fail Rev
, vol.15
, pp. 197-207
-
-
Mistry, N.F.1
Cresci, S.2
-
80
-
-
42649104789
-
PGC-1αinhibits oleic acid induced proliferation and migration of rat vascular smooth muscle cells
-
Zhang Y, Liu C, Zhu L, Jiang X, Chen X, Qi X and Liang X, et al. PGC-1αinhibits oleic acid induced proliferation and migration of rat vascular smooth muscle cells. PLoS One 2007, 2: e1137.
-
(2007)
PLoS One
, vol.2
-
-
Zhang, Y.1
Liu, C.2
Zhu, L.3
Jiang, X.4
Chen, X.5
Qi, X.6
Liang, X.7
-
81
-
-
58449132292
-
PGC-1αis a key regulator of glucose-induced proliferation and migration in vascular smooth muscle cells
-
Zhu L, Sun G, Zhang H, Zhang Y, Chen X, Jiang X and Jiang X, et al. PGC-1αis a key regulator of glucose-induced proliferation and migration in vascular smooth muscle cells. PLoS One 2009, 4: e4182.
-
(2009)
PLoS One
, vol.4
-
-
Zhu, L.1
Sun, G.2
Zhang, H.3
Zhang, Y.4
Chen, X.5
Jiang, X.6
Jiang, X.7
-
82
-
-
19444365211
-
PGC-1α regulates the mitochondrial antioxidant defense system in vascular endothelial cells
-
DOI 10.1016/j.cardiores.2005.01.026, PII S0008636305000763
-
Valle I, Alvarez-Barrientos A, Arza E, Lamas S and Monsalve M. PGC-1αregulates the mitochondrial antioxidant defense system in vascular endothelial cells. Cardiovasc Res 2005, 66: 562-573. (Pubitemid 40725768)
-
(2005)
Cardiovascular Research
, vol.66
, Issue.3
, pp. 562-573
-
-
Valle, I.1
Alvarez-Barrientos, A.2
Arza, E.3
Lamas, S.4
Monsalve, M.5
-
83
-
-
60849109499
-
PGC-1αas modifier of onset age in huntington disease
-
Taherzadeh-Fard E, Saft C, Andrich J, Wieczorek S and Arning L. PGC-1αas modifier of onset age in Huntington disease. Mol Neurodegener 2009, 4: 10.
-
(2009)
Mol Neurodegener
, vol.4
, pp. 10
-
-
Taherzadeh-Fard, E.1
Saft, C.2
Andrich, J.3
Wieczorek, S.4
Arning, L.5
-
84
-
-
34147109662
-
PGC-1α regulates the neuromuscular junction program and ameliorates Duchenne muscular dystrophy
-
DOI 10.1101/gad.1525107
-
Handschin C, Kobayashi YM, Chin S, Seale P, Campbell KP and Spiegelman BM. PGC-1αregulates the neuromuscular junction program and ameliorates Duchenne muscular dystrophy. Genes Dev 2007, 21: 770-783. (Pubitemid 46572357)
-
(2007)
Genes and Development
, vol.21
, Issue.7
, pp. 770-783
-
-
Handschin, C.1
Kobayashi, Y.M.2
Chin, S.3
Seale, P.4
Campbell, K.P.5
Spiegelman, B.M.6
-
85
-
-
15444380906
-
The localization and reduction of nuclear staining of PPARγand PGC-1 in human breast cancer
-
Watkins G, Douglas-Jones A, Mansel RE and Jiang WG. The localization and reduction of nuclear staining of PPARγand PGC-1 in human breast cancer. Oncol Rep 2004, 12: 483-488.
-
(2004)
Oncol Rep
, vol.12
, pp. 483-488
-
-
Watkins, G.1
Douglas-Jones, A.2
Mansel, R.E.3
Jiang, W.G.4
-
86
-
-
0345167182
-
Peroxisome proliferator-activated receptors (PPARs) and associated transcription factors in colon cancer: Reduced expression of PPARγ-coactivator 1 (PGC-1)
-
DOI 10.1016/j.canlet.2003.08.024
-
Feilchenfeldt J, Bründler MA, Soravia C, Tötsch M and Meier CA. Peroxisome proliferator-activated receptors (PPARs) and associated transcription factors in colon cancer: reduced expression of PPARγ-coactivator 1 (PGC-1). Cancer Lett 2004, 203: 25-33. (Pubitemid 37506080)
-
(2004)
Cancer Letters
, vol.203
, Issue.1
, pp. 25-33
-
-
Feilchenfeldt, J.1
Brundler, M.-A.2
Soravia, C.3
Totsch, M.4
Meier, C.A.5
-
87
-
-
77950476069
-
Down-regulation of PGC-1αexpression in human hepatocellular carcinoma
-
Ba Y, Zhang CN, Zhang Y and Zhang CY. Down-regulation of PGC-1αexpression in human hepatocellular carcinoma. Zhonghua Zhong Liu Za Zhi 2008, 30: 593-597.
-
(2008)
Zhonghua Zhong Liu za Zhi
, vol.30
, pp. 593-597
-
-
Ba, Y.1
Zhang, C.N.2
Zhang, Y.3
Zhang, C.Y.4
-
88
-
-
34247346466
-
PGC-1α induces apoptosis in human epithelial ovarian cancer cells through a PPARγ-dependent pathway
-
DOI 10.1038/cr.2007.11, PII CR200711
-
Zhang Y, Ba Y, Liu C, Sun G, Ding L, Gao S and Hao J, et al. PGC-1αinduces apoptosis in human epithelial ovarian cancer cells through a PPARγ-dependent pathway. Cell Res 2007, 17: 363-373. (Pubitemid 46639941)
-
(2007)
Cell Research
, vol.17
, Issue.4
, pp. 363-373
-
-
Zhang, Y.1
Ba, Y.2
Liu, C.3
Sun, G.4
Ding, L.5
Gao, S.6
Hao, J.7
Yu, Z.8
Zhang, J.9
Zen, K.10
Tong, Z.11
Xiang, Y.12
Zhang, C.-Y.13
-
90
-
-
70450252013
-
Alternative mRNA splicing produces a novel biologically active short isoform of PGC-1α
-
Zhang Y, Huypens P, Adamson AW, Chang JS, Henagan TM, Boudreau A and Lenard NR, et al. Alternative mRNA splicing produces a novel biologically active short isoform of PGC-1α. J Biol Chem 2009, 284: 32813-32826.
-
(2009)
J Biol Chem
, vol.284
, pp. 32813-32826
-
-
Zhang, Y.1
Huypens, P.2
Adamson, A.W.3
Chang, J.S.4
Henagan, T.M.5
Boudreau, A.6
Lenard, N.R.7
|