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Volumn 92, Issue 6, 2005, Pages 1165-1172

Aberrant DNA methylation associated with silencing BNIP3 gene expression in haematopoietic tumours

Author keywords

Chromatin; DNA methylation; Epigenetics

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; DNA; HISTONE H3; METHYLTRANSFERASE INHIBITOR; PROTEIN BCL 2; PROTEIN BNIP3; BNIP3 PROTEIN, HUMAN; MEMBRANE PROTEIN; ONCOPROTEIN;

EID: 20244368980     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjc.6602422     Document Type: Article
Times cited : (97)

References (38)
  • 3
    • 0033601073 scopus 로고    scopus 로고
    • Methylation-induced repression - Belts, braces, and chromatin
    • Bird AP, Wolffe AP (1999) Methylation-induced repression - belts, braces, and chromatin. Cell 99: 451-454
    • (1999) Cell , vol.99 , pp. 451-454
    • Bird, A.P.1    Wolffe, A.P.2
  • 5
    • 0034255036 scopus 로고    scopus 로고
    • Expression of the gene encoding the proapoptotic Nip3 protein is induced by hypoxia
    • Bruick RK (2000) Expression of the gene encoding the proapoptotic Nip3 protein is induced by hypoxia. Proc Natl Acad Sci USA 97: 9082-9087
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 9082-9087
    • Bruick, R.K.1
  • 6
    • 0032948005 scopus 로고    scopus 로고
    • Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer
    • Cameron EE, Bachman KE, Myohanen S, Herman JG, Baylin SB (1999) Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer. Nat Genet 21: 103-107
    • (1999) Nat Genet , vol.21 , pp. 103-107
    • Cameron, E.E.1    Bachman, K.E.2    Myohanen, S.3    Herman, J.G.4    Baylin, S.B.5
  • 10
    • 0037047692 scopus 로고    scopus 로고
    • Hypoxia, BNip3 proteins, and the mitochondrial death pathway in cardiomyocytes
    • Crow MT (2002) Hypoxia, BNip3 proteins, and the mitochondrial death pathway in cardiomyocytes. Circ Res 91: 183-185
    • (2002) Circ Res , vol.91 , pp. 183-185
    • Crow, M.T.1
  • 11
    • 0037115392 scopus 로고    scopus 로고
    • Dependence of histone modifications and gene expression on DNA hypermethylation in cancer
    • Fahrner JA, Eguchi S, Herman JG, Baylin SB (2002) Dependence of histone modifications and gene expression on DNA hypermethylation in cancer. Cancer Res 62: 7213-7218
    • (2002) Cancer Res , vol.62 , pp. 7213-7218
    • Fahrner, J.A.1    Eguchi, S.2    Herman, J.G.3    Baylin, S.B.4
  • 14
    • 0036359548 scopus 로고    scopus 로고
    • Hypoxia - A key regulatory factor in tumour growth
    • Harris AL (2002) Hypoxia - a key regulatory factor in tumour growth. Nat Rev Cancer 2: 38-47
    • (2002) Nat Rev Cancer , vol.2 , pp. 38-47
    • Harris, A.L.1
  • 15
    • 0036274359 scopus 로고    scopus 로고
    • The fundamental role of epigenetic events in cancer
    • Jones PA, Baylin SB (2002) The fundamental role of epigenetic events in cancer. Nat Rev Genet 3: 415-428
    • (2002) Nat Rev Genet , vol.3 , pp. 415-428
    • Jones, P.A.1    Baylin, S.B.2
  • 16
    • 0032960181 scopus 로고    scopus 로고
    • Cancer epigenetics comes of age
    • Jones PA, Laird PW (1999) Cancer epigenetics comes of age. Nat Genet 21: 163-167
    • (1999) Nat Genet , vol.21 , pp. 163-167
    • Jones, P.A.1    Laird, P.W.2
  • 17
    • 0042346386 scopus 로고    scopus 로고
    • Enrichment for histone H3 lysine 9 methylation at Alu repeats in human cells
    • Kondo Y, Issa JP (2003) Enrichment for histone H3 lysine 9 methylation at Alu repeats in human cells. J Biol Chem 278: 27658-27662
    • (2003) J Biol Chem , vol.278 , pp. 27658-27662
    • Kondo, Y.1    Issa, J.P.2
  • 18
    • 0036789917 scopus 로고    scopus 로고
    • Hypoxia and acidosis activate cardiac myocyte death through the Bcl-2 family protein BNIP3
    • Kubasiak LA, Hernandez OM, Bishopric NH, Webster KA (2002) Hypoxia and acidosis activate cardiac myocyte death through the Bcl-2 family protein BNIP3. Proc Natl Acad Sci USA 99: 12825-12830
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 12825-12830
    • Kubasiak, L.A.1    Hernandez, O.M.2    Bishopric, N.H.3    Webster, K.A.4
  • 19
    • 0035942170 scopus 로고    scopus 로고
    • Selective association of the methyl-CpG binding protein MBD2 with the silent p14/p16 locus in human neoplasia
    • Magdinier F, Wolffe AP (2001) Selective association of the methyl-CpG binding protein MBD2 with the silent p14/p16 locus in human neoplasia. Proc Natl Acad Sci USA 98: 4990-4995
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 4990-4995
    • Magdinier, F.1    Wolffe, A.P.2
  • 21
    • 0037111665 scopus 로고    scopus 로고
    • BCR/ABL induces expression of vascular endothelial growth factor and its transcriptional activator, hypoxia inducible factor-1 alpha, through a pathway involving phosphoinositide 3-kinase and the mammalian target of rapamycin
    • Mayerhofer M, Valent P, Sperr WR, Griffin JD, Sillaber C (2002) BCR/ABL induces expression of vascular endothelial growth factor and its transcriptional activator, hypoxia inducible factor-1 alpha, through a pathway involving phosphoinositide 3-kinase and the mammalian target of rapamycin. Blood 100: 3767-3775
    • (2002) Blood , vol.100 , pp. 3767-3775
    • Mayerhofer, M.1    Valent, P.2    Sperr, W.R.3    Griffin, J.D.4    Sillaber, C.5
  • 22
    • 0036387011 scopus 로고    scopus 로고
    • DNA methylation changes in leukaemia
    • Melki JR, Clark SJ (2002) DNA methylation changes in leukaemia. Semin Cancer Biol 12: 347-357
    • (2002) Semin Cancer Biol , vol.12 , pp. 347-357
    • Melki, J.R.1    Clark, S.J.2
  • 23
    • 0035890665 scopus 로고    scopus 로고
    • Altered chromatin structure associated with methylation-induced gene silencing in cancer cells: Correlation of accessibility, methylation, MeCP2 binding and acetylation
    • Nguyen CT, Gonzales FA, Jones PA (2001) Altered chromatin structure associated with methylation-induced gene silencing in cancer cells: correlation of accessibility, methylation, MeCP2 binding and acetylation. Nucleic Acids Res 29: 4598-4606
    • (2001) Nucleic Acids Res , vol.29 , pp. 4598-4606
    • Nguyen, C.T.1    Gonzales, F.A.2    Jones, P.A.3
  • 24
    • 0037112369 scopus 로고    scopus 로고
    • Histone H3-lysine 9 methylation is associated with aberrant gene silencing in cancer cells and is rapidly reversed by 5-aza-2′- deoxycytidine
    • Nguyen CT, Weisenberger DJ, Velicescu M, Gonzales FA, Lin JC, Liang G, Jones PA (2002) Histone H3-lysine 9 methylation is associated with aberrant gene silencing in cancer cells and is rapidly reversed by 5-aza-2′- deoxycytidine. Cancer Res 62: 6456-6461
    • (2002) Cancer Res , vol.62 , pp. 6456-6461
    • Nguyen, C.T.1    Weisenberger, D.J.2    Velicescu, M.3    Gonzales, F.A.4    Lin, J.C.5    Liang, G.6    Jones, P.A.7
  • 25
    • 0037047647 scopus 로고    scopus 로고
    • Inducible expression of BNIP3 provokes mitochondrial defects and hypoxia-mediated cell death of ventricular myocytes
    • Regula KM, Ens K, Kirshenbaum LA (2002) Inducible expression of BNIP3 provokes mitochondrial defects and hypoxia-mediated cell death of ventricular myocytes. Circ Res 91: 226-231
    • (2002) Circ Res , vol.91 , pp. 226-231
    • Regula, K.M.1    Ens, K.2    Kirshenbaum, L.A.3
  • 27
    • 0031918244 scopus 로고    scopus 로고
    • Regulation of proliferation-survival decisions during tumor cell hypoxia
    • Schmaltz C, Hardenbergh PH, Wells A, Fisher DE (1998) Regulation of proliferation-survival decisions during tumor cell hypoxia. Mol Cell Biol 18: 2845-2854
    • (1998) Mol Cell Biol , vol.18 , pp. 2845-2854
    • Schmaltz, C.1    Hardenbergh, P.H.2    Wells, A.3    Fisher, D.E.4
  • 28
    • 0033233243 scopus 로고    scopus 로고
    • Regulation of mammalian O2 homeostasis by hypoxia-inducible factor 1
    • Semenza GL (1999) Regulation of mammalian O2 homeostasis by hypoxia-inducible factor 1. Annu Rev Cell Dev Biol 15: 551-578
    • (1999) Annu Rev Cell Dev Biol , vol.15 , pp. 551-578
    • Semenza, G.L.1
  • 29
    • 0037625237 scopus 로고    scopus 로고
    • Aberrant DNA methylation of p57KIP2 identifies a cell-cycle regulatory pathway with prognostic impact in adult acute lymphocytic leukemia
    • Shen L, Toyota M, Kondo Y, Obata T, Daniel S, Pierce S, Imai K, Kantarjian HM, Issa JP, Garcia-Manero G (2003) Aberrant DNA methylation of p57KIP2 identifies a cell-cycle regulatory pathway with prognostic impact in adult acute lymphocytic leukemia. Blood 101: 4131-4136
    • (2003) Blood , vol.101 , pp. 4131-4136
    • Shen, L.1    Toyota, M.2    Kondo, Y.3    Obata, T.4    Daniel, S.5    Pierce, S.6    Imai, K.7    Kantarjian, H.M.8    Issa, J.P.9    Garcia-Manero, G.10
  • 30
    • 1342333155 scopus 로고    scopus 로고
    • Expression of the cell death genes BNip3 and NIX in ductal carcinoma in situ of the breast; correlation of BNip3 levels with necrosis and grade
    • Sowter HM, Ferguson M, Pym C, Watson P, Fox SB, Han C, Harris AL (2003) Expression of the cell death genes BNip3 and NIX in ductal carcinoma in situ of the breast; correlation of BNip3 levels with necrosis and grade. J Pathol 201: 573-580
    • (2003) J Pathol , vol.201 , pp. 573-580
    • Sowter, H.M.1    Ferguson, M.2    Pym, C.3    Watson, P.4    Fox, S.B.5    Han, C.6    Harris, A.L.7
  • 31
    • 0035884701 scopus 로고    scopus 로고
    • HIF-1-dependent regulation of hypoxic induction of the cell death factors BNIP3 and NIX in human tumors
    • Sowter HM, Ratcliffe PJ, Watson P, Greenberg AH, Harris AL (2001) HIF-1-dependent regulation of hypoxic induction of the cell death factors BNIP3 and NIX in human tumors. Cancer Res 61: 6669-6673
    • (2001) Cancer Res , vol.61 , pp. 6669-6673
    • Sowter, H.M.1    Ratcliffe, P.J.2    Watson, P.3    Greenberg, A.H.4    Harris, A.L.5
  • 32
    • 0034662605 scopus 로고    scopus 로고
    • Inactivation of the 14-3-3 sigma gene is associated with 5′ CpG island hypermethylation in human cancers
    • Suzuki H, Itoh F, Toyota M, Kikuchi T, Kakiuchi H, Imai K (2000) Inactivation of the 14-3-3 sigma gene is associated with 5′ CpG island hypermethylation in human cancers. Cancer Res 60: 4353-4357
    • (2000) Cancer Res , vol.60 , pp. 4353-4357
    • Suzuki, H.1    Itoh, F.2    Toyota, M.3    Kikuchi, T.4    Kakiuchi, H.5    Imai, K.6
  • 33
    • 0032739329 scopus 로고    scopus 로고
    • CpG island methylator phenotypes in aging and cancer
    • Toyota M, Issa JP (1999) CpG island methylator phenotypes in aging and cancer. Semin Cancer Biol 9: 349-357
    • (1999) Semin Cancer Biol , vol.9 , pp. 349-357
    • Toyota, M.1    Issa, J.P.2
  • 37
    • 0030825309 scopus 로고    scopus 로고
    • COBRA: A sensitive and quantitative DNA methylation assay
    • Xiong Z, Laird PW (1997) COBRA: a sensitive and quantitative DNA methylation assay. Nucleic Acids Res 25: 2532-2534
    • (1997) Nucleic Acids Res , vol.25 , pp. 2532-2534
    • Xiong, Z.1    Laird, P.W.2
  • 38
    • 0032524656 scopus 로고    scopus 로고
    • Adenovirus E1B-19K/BCL-2 interacting protein BNIP3 contains a BH3 domain and a mitochondrial targeting sequence
    • Yasuda M, Theodorakis P, Subramanian T, Chinnadurai G (1998) Adenovirus E1B-19K/BCL-2 interacting protein BNIP3 contains a BH3 domain and a mitochondrial targeting sequence. J Biol Chem 273: 12415-12421
    • (1998) J Biol Chem , vol.273 , pp. 12415-12421
    • Yasuda, M.1    Theodorakis, P.2    Subramanian, T.3    Chinnadurai, G.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.