-
2
-
-
0007592085
-
Plasma cell proliferative disorders
-
Hoffman R (ed). Churchill Livingstone: New York
-
Kyle RA. Plasma cell proliferative disorders. In: Hoffman R (ed). Hematology: Basic Principles and Practice, 3rd edn. Churchill Livingstone: New York, 1999, pp 1021-1038.
-
(1999)
Hematology: Basic Principles and Practice, 3rd Edn.
, pp. 1021-1038
-
-
Kyle, R.A.1
-
3
-
-
0037148921
-
A long-term study of prognosis in monoclonal gammopathy of undetermined significance
-
Kyle RA, Therneau TM, Rajkumar SV, et al. A long-term study of prognosis in monoclonal gammopathy of undetermined significance. N Engl J Med 2002;346:564-569.
-
(2002)
N Engl J Med
, vol.346
, pp. 564-569
-
-
Kyle, R.A.1
Therneau, T.M.2
Rajkumar, S.V.3
-
4
-
-
0031985198
-
Multiple myeloma: Increasing evidence for a multistep transformation process
-
Hallek M, Bergsagel PL, Anderson KC. Multiple myeloma: increasing evidence for a multistep transformation process. Blood 1998;91:3-21.
-
(1998)
Blood
, vol.91
, pp. 3-21
-
-
Hallek, M.1
Bergsagel, P.L.2
Anderson, K.C.3
-
5
-
-
6444243522
-
DNA mismatch repair pathway defects in the pathogenesis and evolution of myeloma
-
Velangi MR, Matheson EC, Morgan GJ, et al. DNA mismatch repair pathway defects in the pathogenesis and evolution of myeloma. Carcinogenesis 2004;25:1795-1803.
-
(2004)
Carcinogenesis
, vol.25
, pp. 1795-1803
-
-
Velangi, M.R.1
Matheson, E.C.2
Morgan, G.J.3
-
6
-
-
0036274359
-
The fundamental role of epigenetic events in cancer
-
Jones PA, Baylin SB. The fundamental role of epigenetic events in cancer. Nat Rev Genet 2002;3:415-428.
-
(2002)
Nat Rev Genet
, vol.3
, pp. 415-428
-
-
Jones, P.A.1
Baylin, S.B.2
-
7
-
-
0025891856
-
Allele-specific hypermethylation of the retinoblastoma tumor-suppressor gene
-
Sakai T, Toguchida J, Ohtani N, et al. Allele-specific hypermethylation of the retinoblastoma tumor-suppressor gene. Am J Hum Genet 1991;48:880-888.
-
(1991)
Am J Hum Genet
, vol.48
, pp. 880-888
-
-
Sakai, T.1
Toguchida, J.2
Ohtani, N.3
-
8
-
-
0036240381
-
Impaired expression and promotor hypermethylation of O6-methylguanine-DNA methyltransferase in retinoblastoma tissues
-
Choy KW, Pang CP, To KF, et al. Impaired expression and promotor hypermethylation of O6-methylguanine-DNA methyltransferase in retinoblastoma tissues. Invest Ophthalmol Vis Sci 2002;43:1344-1349.
-
(2002)
Invest Ophthalmol Vis Sci
, vol.43
, pp. 1344-1349
-
-
Choy, K.W.1
Pang, C.P.2
To, K.F.3
-
9
-
-
18844394738
-
Roles of mismatch repair proteins hMSH2 and hMLH1 in the development of sporadic breast cancer
-
Murata H, Khattar NH, Gu L, et al. Roles of mismatch repair proteins hMSH2 and hMLH1 in the development of sporadic breast cancer. Cancer Lett 2005;223:143-150.
-
(2005)
Cancer Lett
, vol.223
, pp. 143-150
-
-
Murata, H.1
Khattar, N.H.2
Gu, L.3
-
10
-
-
2442628250
-
DNA methylation profiles of lymphoid and hematopoietic malignancies
-
Takahashi T, Shivapurkar N, Reddy J, et al. DNA methylation profiles of lymphoid and hematopoietic malignancies. Clin Cancer Res 2004;10:2928-2935.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 2928-2935
-
-
Takahashi, T.1
Shivapurkar, N.2
Reddy, J.3
-
11
-
-
13144290928
-
Methylation profiles of thirty four promoter-CpG islands and concordant methylation behaviours of sixteen genes that may contribute to carcinogenesis of astrocytoma
-
Yu J, Zhang H, Gu J, et al. Methylation profiles of thirty four promoter-CpG islands and concordant methylation behaviours of sixteen genes that may contribute to carcinogenesis of astrocytoma. BMC Cancer 2004;4:65-80.
-
(2004)
BMC Cancer
, vol.4
, pp. 65-80
-
-
Yu, J.1
Zhang, H.2
Gu, J.3
-
12
-
-
16544395591
-
DNA methylation and cancer
-
Das PM, Singal R. DNA methylation and cancer. J Clin Oncol 2004;22:4632-4642.
-
(2004)
J Clin Oncol
, vol.22
, pp. 4632-4642
-
-
Das, P.M.1
Singal, R.2
-
13
-
-
0032706744
-
hMLH1 promoter hypermethylation is an early event in human endometrial tumorigenesis
-
Esteller M, Catasus L, Matias-Guiu X, et al. hMLH1 promoter hypermethylation is an early event in human endometrial tumorigenesis. Am J Pathol 1999;155:1767-1772.
-
(1999)
Am J Pathol
, vol.155
, pp. 1767-1772
-
-
Esteller, M.1
Catasus, L.2
Matias-Guiu, X.3
-
14
-
-
0031908505
-
The effect of different chemotherapeutic agents on the enrichment of DNA mismatch repair-deficient tumour cells
-
Fink D, Nebel S, Norris PS, et al. The effect of different chemotherapeutic agents on the enrichment of DNA mismatch repair-deficient tumour cells. Br J Cancer 1998;77:703-708.
-
(1998)
Br J Cancer
, vol.77
, pp. 703-708
-
-
Fink, D.1
Nebel, S.2
Norris, P.S.3
-
15
-
-
0031748851
-
Analysis of DNA mismatch repair proteins in human medulloblastoma
-
Lee SE, Johnson SP, Hale LP, et al. Analysis of DNA mismatch repair proteins in human medulloblastoma. Clin Cancer Res 1998;4:1415-1419.
-
(1998)
Clin Cancer Res
, vol.4
, pp. 1415-1419
-
-
Lee, S.E.1
Johnson, S.P.2
Hale, L.P.3
-
17
-
-
0027314411
-
Microsatellite instability in cancer of the proximal colon
-
Thibodeau SN, Bren G, Schaid D. Microsatellite instability in cancer of the proximal colon. Science 1993;260:816-819.
-
(1993)
Science
, vol.260
, pp. 816-819
-
-
Thibodeau, S.N.1
Bren, G.2
Schaid, D.3
-
18
-
-
12444269008
-
BRAF/K-ras mutation, microsatellite instability, and promoter hypermethylation of hMLH1/MGMT in human gastric carcinomas
-
Wu M, Semba S, Oue N, et al. BRAF/K-ras mutation, microsatellite instability, and promoter hypermethylation of hMLH1/MGMT in human gastric carcinomas. Gastric Cancer 2004;7:246-253.
-
(2004)
Gastric Cancer
, vol.7
, pp. 246-253
-
-
Wu, M.1
Semba, S.2
Oue, N.3
-
19
-
-
13644266447
-
Dormant hypermethylated tumour suppressor genes: Questions and answers
-
Esteller M. Dormant hypermethylated tumour suppressor genes: questions and answers. J Pathol 2005;205:172-180.
-
(2005)
J Pathol
, vol.205
, pp. 172-180
-
-
Esteller, M.1
-
20
-
-
1942469956
-
MGMT: Its role in cancer aetiology and cancer therapeutics
-
Gerson SL. MGMT: its role in cancer aetiology and cancer therapeutics. Nat Rev Cancer 2004;4:296-307.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 296-307
-
-
Gerson, S.L.1
-
21
-
-
0030874380
-
Methylation of discrete regions of the O6-methylguanine DNA methyltransferase (MGMT) CpG island is associated with heterochromatinization of the MGMT transcription start site and silencing of the gene
-
Watts GS, Pieper RO, Costello JF, et al. Methylation of discrete regions of the O6-methylguanine DNA methyltransferase (MGMT) CpG island is associated with heterochromatinization of the MGMT transcription start site and silencing of the gene. Mol Cell Biol 1997;17:5612-5619.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 5612-5619
-
-
Watts, G.S.1
Pieper, R.O.2
Costello, J.F.3
-
22
-
-
0029162051
-
The methylation status of the gene for O6-methylguanine-DNA methyltransferase in human Mer+ and Mer- cells
-
Skorpen F, Krokan HE. The methylation status of the gene for O6-methylguanine-DNA methyltransferase in human Mer+ and Mer- cells. Carcinogenesis 1995;16: 1857-1863.
-
(1995)
Carcinogenesis
, vol.16
, pp. 1857-1863
-
-
Skorpen, F.1
Krokan, H.E.2
-
23
-
-
0033557903
-
Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia
-
Esteller M, Hamilton SR, Burger PC, et al. Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia. Cancer Res 1999;59:793-797.
-
(1999)
Cancer Res
, vol.59
, pp. 793-797
-
-
Esteller, M.1
Hamilton, S.R.2
Burger, P.C.3
-
24
-
-
0035874892
-
Promoter hypermethylation of the DNA repair gene O(6)-methylguanine-DNA methyltransferase is associated with the presence of G:C to A:T transition mutations in p53 in human colorectal tumorigenesis
-
Esteller M, Risques RA, Toyota M, et al. Promoter hypermethylation of the DNA repair gene O(6)-methylguanine-DNA methyltransferase is associated with the presence of G:C to A:T transition mutations in p53 in human colorectal tumorigenesis. Cancer Res 2001;61:4689-4692.
-
(2001)
Cancer Res
, vol.61
, pp. 4689-4692
-
-
Esteller, M.1
Risques, R.A.2
Toyota, M.3
-
25
-
-
8944235348
-
A plasmocyte selective monoclonal antibody (B-B4) recognizes syndecan-1
-
Wijdenes J, Vooijs WC, Clement C, et al. A plasmocyte selective monoclonal antibody (B-B4) recognizes syndecan-1. Br J Haematol 1996;94:318-323.
-
(1996)
Br J Haematol
, vol.94
, pp. 318-323
-
-
Wijdenes, J.1
Vooijs, W.C.2
Clement, C.3
-
26
-
-
0029843950
-
Methylation-specific PCR: A novel PCR assay for methylation status of CpG islands
-
USA
-
Herman JG, Graff JR, Myohanen S, et al. Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands. Proc Natl Acad Sci USA 1996;93:9821-9826.
-
(1996)
Proc Natl Acad Sci
, vol.93
, pp. 9821-9826
-
-
Herman, J.G.1
Graff, J.R.2
Myohanen, S.3
-
27
-
-
0037287135
-
Promoter hypermethylation and inactivation of hMLH1, a DNA mismatch repair gene, in head and neck squamous cell carcinoma
-
Liu K, Zuo C, Luo QK, et al. Promoter hypermethylation and inactivation of hMLH1, a DNA mismatch repair gene, in head and neck squamous cell carcinoma. Diagn Mol Pathol 2003;12:50-56.
-
(2003)
Diagn Mol Pathol
, vol.12
, pp. 50-56
-
-
Liu, K.1
Zuo, C.2
Luo, Q.K.3
-
28
-
-
0038270068
-
Loss of expression of DNA repair enzymes MGMT, hMLH1, and hMSH2 during tumor progression in gastric cancer
-
Kitajima Y, Miyazaki K, Matsukura S, et al. Loss of expression of DNA repair enzymes MGMT, hMLH1, and hMSH2 during tumor progression in gastric cancer. Gastric Cancer 2003;6:86-95.
-
(2003)
Gastric Cancer
, vol.6
, pp. 86-95
-
-
Kitajima, Y.1
Miyazaki, K.2
Matsukura, S.3
-
29
-
-
20344396907
-
Mismatch repair genes (hMLH1, hPMS1, hPMS2, GTBP/hMSH6, hMSH2) in the pathogenesis of hepatocellular carcinoma
-
Zekri AR, Sabry GM, Bahnassy AA, et al. Mismatch repair genes (hMLH1, hPMS1, hPMS2, GTBP/hMSH6, hMSH2) in the pathogenesis of hepatocellular carcinoma. World J Gastroenterol 2005;11:3020-3026.
-
(2005)
World J Gastroenterol
, vol.11
, pp. 3020-3026
-
-
Zekri, A.R.1
Sabry, G.M.2
Bahnassy, A.A.3
-
30
-
-
13144266670
-
Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma
-
USA
-
Herman JG, Umar A, Polyak K, et al. Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma. Proc Natl Acad Sci USA 1998;95:6870-6875.
-
(1998)
Proc Natl Acad Sci
, vol.95
, pp. 6870-6875
-
-
Herman, J.G.1
Umar, A.2
Polyak, K.3
-
31
-
-
0031024824
-
Mutations and loss of expression of a mismatch repair gene, hMLH1, in leukemia and lymphoma cell lines
-
Hangaishi A, Ogawa S, Mitani K, et al. Mutations and loss of expression of a mismatch repair gene, hMLH1, in leukemia and lymphoma cell lines. Blood 1997;89:1740-1747.
-
(1997)
Blood
, vol.89
, pp. 1740-1747
-
-
Hangaishi, A.1
Ogawa, S.2
Mitani, K.3
-
32
-
-
14744274735
-
Methylation analysis of the cell cycle control genes in myelofibrosis with myeloid metaplasia
-
Kumagai T, Tefferi A, Jones L, et al. Methylation analysis of the cell cycle control genes in myelofibrosis with myeloid metaplasia. Leuk Res 2005;29:511-515.
-
(2005)
Leuk Res
, vol.29
, pp. 511-515
-
-
Kumagai, T.1
Tefferi, A.2
Jones, L.3
-
33
-
-
4844221344
-
Promoter methylation and expression of DNA repair genes hMLH1 and MGMT in acute myeloid leukemia
-
Lenz G, Hutter G, Hiddemann W, et al. Promoter methylation and expression of DNA repair genes hMLH1 and MGMT in acute myeloid leukemia. Ann Hematol 2004;83:628-633.
-
(2004)
Ann Hematol
, vol.83
, pp. 628-633
-
-
Lenz, G.1
Hutter, G.2
Hiddemann, W.3
-
35
-
-
6344229983
-
DNA methylation changes in multiple myeloma
-
Galm O, Wilop S, Reichelt J, et al. DNA methylation changes in multiple myeloma. Leukemia 2004;18:1687-1692.
-
(2004)
Leukemia
, vol.18
, pp. 1687-1692
-
-
Galm, O.1
Wilop, S.2
Reichelt, J.3
-
36
-
-
0036194344
-
Mismatch repair gene expression in malignant lymphoproliferative disorders of B-cell origin
-
Kotoula V, Hytiroglou P, Kaloutsi V, et al. Mismatch repair gene expression in malignant lymphoproliferative disorders of B-cell origin. Leuk Lymphoma 2002;43:393-399.
-
(2002)
Leuk Lymphoma
, vol.43
, pp. 393-399
-
-
Kotoula, V.1
Hytiroglou, P.2
Kaloutsi, V.3
-
37
-
-
2642532716
-
DNA-methylation analysis identifies the E-cadherin gene as a potential marker of disease progression in patients with monoclonal gammopathies
-
Seidl S, Ackermann J, Kaufmann H, et al. DNA-methylation analysis identifies the E-cadherin gene as a potential marker of disease progression in patients with monoclonal gammopathies. Cancer 2004;100:2598-2606.
-
(2004)
Cancer
, vol.100
, pp. 2598-2606
-
-
Seidl, S.1
Ackermann, J.2
Kaufmann, H.3
-
38
-
-
2942572047
-
Aberrant promoter methylation of multiple genes throughout the clinico-pathologic spectrum of B-cell neoplasia
-
Rossi D, Capello D, Gloghini A, et al. Aberrant promoter methylation of multiple genes throughout the clinico-pathologic spectrum of B-cell neoplasia. Haematologica 2004;89:154-164.
-
(2004)
Haematologica
, vol.89
, pp. 154-164
-
-
Rossi, D.1
Capello, D.2
Gloghini, A.3
-
39
-
-
1042289347
-
Methylation profiling in multiple myeloma
-
Chim CS, Kwong YL, Fung TK, et al. Methylation profiling in multiple myeloma. Leuk Res 2004;28:379-385.
-
(2004)
Leuk Res
, vol.28
, pp. 379-385
-
-
Chim, C.S.1
Kwong, Y.L.2
Fung, T.K.3
-
40
-
-
0037005988
-
Hypermethylation of the DNA repair gene O(6)-methylguanine DNA methyltransferase and survival of patients with diffuse large B-cell lymphoma
-
Esteller M, Gaidano G, Goodman SN, et al. Hypermethylation of the DNA repair gene O(6)-methylguanine DNA methyltransferase and survival of patients with diffuse large B-cell lymphoma. J Natl Cancer Inst 2002;94:26-32.
-
(2002)
J Natl Cancer Inst
, vol.94
, pp. 26-32
-
-
Esteller, M.1
Gaidano, G.2
Goodman, S.N.3
-
41
-
-
0242361132
-
Frequent aberrant promoter hypermethylation of O6-methylguanine-DNA methyltransferase and death-associated protein kinase genes in immunodeficiency-related lymphomas
-
Rossi D, Gaidano G, Gloghini A, et al. Frequent aberrant promoter hypermethylation of O6-methylguanine-DNA methyltransferase and death-associated protein kinase genes in immunodeficiency-related lymphomas. Br J Haematol 2003;123:475-478.
-
(2003)
Br J Haematol
, vol.123
, pp. 475-478
-
-
Rossi, D.1
Gaidano, G.2
Gloghini, A.3
-
42
-
-
0030972856
-
Methylnitrosourea-induced tumorigenesis in MGMT gene knockout mice
-
Sakumi K, Shiraishi A, Shimizu S, et al. Methylnitrosourea-induced tumorigenesis in MGMT gene knockout mice. Cancer Res 1997;57:2415-2418.
-
(1997)
Cancer Res
, vol.57
, pp. 2415-2418
-
-
Sakumi, K.1
Shiraishi, A.2
Shimizu, S.3
-
43
-
-
14244259066
-
Epigenetic silencing of the human nucleotide excision repair gene, hHR23B, in Interleukin-6-responsive Multiple Myeloma KAS-6/1 Cells
-
Peng B, Hodge DR, Thomas SB, et al. Epigenetic silencing of the human nucleotide excision repair gene, hHR23B, in Interleukin-6-responsive Multiple Myeloma KAS-6/1 Cells. J Biol Chem 2005;280:4182-4187.
-
(2005)
J Biol Chem
, vol.280
, pp. 4182-4187
-
-
Peng, B.1
Hodge, D.R.2
Thomas, S.B.3
-
44
-
-
0942279488
-
Generating mutations but providing chemosensitivity: The role of O6-methylguanine DNA methyltransferase in human cancer
-
Esteller M, Herman JG. Generating mutations but providing chemosensitivity: the role of O6-methylguanine DNA methyltransferase in human cancer. Oncogene 2004;23:1-8.
-
(2004)
Oncogene
, vol.23
, pp. 1-8
-
-
Esteller, M.1
Herman, J.G.2
-
45
-
-
0032574814
-
Separation of killing and tumorigenic effects of an alkylating agent in mice defective in two of the DNA repair genes
-
USA
-
Kawate H, Sakumi K, Tsuzuki T, et al. Separation of killing and tumorigenic effects of an alkylating agent in mice defective in two of the DNA repair genes. Proc Natl Acad Sci USA 1998;95:5116-5120.
-
(1998)
Proc Natl Acad Sci
, vol.95
, pp. 5116-5120
-
-
Kawate, H.1
Sakumi, K.2
Tsuzuki, T.3
-
46
-
-
0033955906
-
A defect in a single allele of the Mlh1 gene causes dissociation of the killing and tumorigenic actions of an alkylating carcinogen in methyltransferase-deficient mice
-
Kawate H, Itoh R, Sakumi K, et al. A defect in a single allele of the Mlh1 gene causes dissociation of the killing and tumorigenic actions of an alkylating carcinogen in methyltransferase-deficient mice. Carcinogenesis 2000;21:301-305.
-
(2000)
Carcinogenesis
, vol.21
, pp. 301-305
-
-
Kawate, H.1
Itoh, R.2
Sakumi, K.3
-
47
-
-
0031804961
-
DNA mismatch repair and cancer
-
Prolla TA. DNA mismatch repair and cancer. Curr Opin Cell Biol 1998;10:311-316.
-
(1998)
Curr Opin Cell Biol
, vol.10
, pp. 311-316
-
-
Prolla, T.A.1
-
48
-
-
13444270782
-
Support for hMLH1 and MGMT silencing as a mechanism of tumorigenesis in the hyperplastic-adenoma-carcinoma (serrated) carcinogenic pathway in the colon
-
Oh K, Redston M, Odze RD. Support for hMLH1 and MGMT silencing as a mechanism of tumorigenesis in the hyperplastic-adenoma-carcinoma (serrated) carcinogenic pathway in the colon. Hum Pathol 2005;36:101-111.
-
(2005)
Hum Pathol
, vol.36
, pp. 101-111
-
-
Oh, K.1
Redston, M.2
Odze, R.D.3
|