메뉴 건너뛰기




Volumn 222, Issue 2, 2005, Pages 247-254

p16 gene methylation lacks correlation with angiogenesis and prognosis in multiple myeloma

Author keywords

Angiogenesis; Multiple myeloma; p16; Prognosis

Indexed keywords

DEXAMETHASONE; DOXORUBICIN; MELPHALAN; PREDNISONE; PROTEIN P16; VASCULOTROPIN; VINCRISTINE;

EID: 18044390654     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2004.09.038     Document Type: Article
Times cited : (21)

References (34)
  • 3
    • 0343048351 scopus 로고    scopus 로고
    • De novo methylation of tumor suppressor gene p16/INK4A is a frequent finding in multiple myeloma patients at diagnosis
    • M. Gonzalez, M.V. Mateos, R. Garcia-Sanz, A. Balanzategui, R. Lopez-Perez, and M.C. Chillon De novo methylation of tumor suppressor gene p16/INK4A is a frequent finding in multiple myeloma patients at diagnosis Leukemia 14 2000 183 187
    • (2000) Leukemia , vol.14 , pp. 183-187
    • Gonzalez, M.1    Mateos, M.V.2    Garcia-Sanz, R.3    Balanzategui, A.4    Lopez-Perez, R.5    Chillon, M.C.6
  • 4
    • 18544379572 scopus 로고    scopus 로고
    • Methylation is an inactivating mechanism of the p16 gene in multiple myeloma associated with high plasma cell proliferation and short survival
    • M.V. Mateos, R. Garcia-Sanz, R. Lopez-Perez, M.J. Moro, E. Ocio, and J. Hernandez Methylation is an inactivating mechanism of the p16 gene in multiple myeloma associated with high plasma cell proliferation and short survival Br. J. Haematol. 118 2002 1034 1040
    • (2002) Br. J. Haematol. , vol.118 , pp. 1034-1040
    • Mateos, M.V.1    Garcia-Sanz, R.2    Lopez-Perez, R.3    Moro, M.J.4    Ocio, E.5    Hernandez, J.6
  • 6
    • 0035992360 scopus 로고    scopus 로고
    • Bone marrow angiogenesis in 400 patients with monoclonal gammopathy of undetermined significance, multiple myeloma, and primary amyloidosis
    • S.V. Rajkumar, R.A. Mesa, R. Fonseca, G. Schroeder, M.F. Plevak, and A. Dispenzieri Bone marrow angiogenesis in 400 patients with monoclonal gammopathy of undetermined significance, multiple myeloma, and primary amyloidosis Clin. Cancer Res. 8 2002 2210 2216
    • (2002) Clin. Cancer Res. , vol.8 , pp. 2210-2216
    • Rajkumar, S.V.1    Mesa, R.A.2    Fonseca, R.3    Schroeder, G.4    Plevak, M.F.5    Dispenzieri, A.6
  • 7
    • 0036037427 scopus 로고    scopus 로고
    • Microvessel density, a surrogate marker of angiogenesis, is significantly related to survival in multiple myeloma patients
    • G. Pruneri, M. Ponzoni, A.J.M. Ferreri, N. Decarli, M. Tresoldi, and F. Raggi Microvessel density, a surrogate marker of angiogenesis, is significantly related to survival in multiple myeloma patients Br. J. Haematol. 118 2002 817 820
    • (2002) Br. J. Haematol. , vol.118 , pp. 817-820
    • Pruneri, G.1    Ponzoni, M.2    Ferreri, A.J.M.3    Decarli, N.4    Tresoldi, M.5    Raggi, F.6
  • 8
    • 0036842215 scopus 로고    scopus 로고
    • Vascular permeability factor/vascular endothelial growth factor: A critical cytokine in tumor angiogenesis and a potential target for diagnosis and therapy
    • H.F. Dvorak Vascular permeability factor/vascular endothelial growth factor: a critical cytokine in tumor angiogenesis and a potential target for diagnosis and therapy J. Clin. Oncol. 20 2002 4368 4380
    • (2002) J. Clin. Oncol. , vol.20 , pp. 4368-4380
    • Dvorak, H.F.1
  • 9
    • 0035880256 scopus 로고    scopus 로고
    • Vascular endothelial growth factor triggers signaling cascades mediating multiple myeloma cell growth and migration
    • K. Podar, Y.T. Tay, F.E. Davies, S. Lentzsch, M. Sattler, and T. Hideshima Vascular endothelial growth factor triggers signaling cascades mediating multiple myeloma cell growth and migration Blood 98 2001 428 435
    • (2001) Blood , vol.98 , pp. 428-435
    • Podar, K.1    Tay, Y.T.2    Davies, F.E.3    Lentzsch, S.4    Sattler, M.5    Hideshima, T.6
  • 10
    • 0033178714 scopus 로고    scopus 로고
    • Restoration of wild-type p16 down-regulates vascular endothelial growth factor expression and inhibits angiogenesis in human gliomas
    • H. Harada, K. Nakagawa, S. Iwata, M. Saito, Y. Kumon, and S. Sakaki Restoration of wild-type p16 down-regulates vascular endothelial growth factor expression and inhibits angiogenesis in human gliomas Cancer Res. 59 1999 3783 3789
    • (1999) Cancer Res. , vol.59 , pp. 3783-3789
    • Harada, H.1    Nakagawa, K.2    Iwata, S.3    Saito, M.4    Kumon, Y.5    Sakaki, S.6
  • 12
    • 0031985198 scopus 로고    scopus 로고
    • Multiple myeloma: Increasing evidence for a multistep transformation process
    • M. Hallek, P.L. Bergsagel, and K.C. Anderson Multiple myeloma: increasing evidence for a multistep transformation process Blood 91 1998 3 21
    • (1998) Blood , vol.91 , pp. 3-21
    • Hallek, M.1    Bergsagel, P.L.2    Anderson, K.C.3
  • 13
    • 0022973287 scopus 로고
    • Staging and kinetics of multiple myeloma
    • B.G.M. Durie, and S.E. Salmon Staging and kinetics of multiple myeloma Semin. Oncol. 13 1986 300 309
    • (1986) Semin. Oncol. , vol.13 , pp. 300-309
    • Durie, B.G.M.1    Salmon, S.E.2
  • 14
    • 0033566692 scopus 로고    scopus 로고
    • Quantitative analysis of aberrant p16 methylation using real-time quantitative methylation-specific polymerase chain reaction
    • Y.M.D. Lo, I.H.N. Wong, J. Zhang, M.S.C. Tein, M.H.L. Ng, and N.M. Hjelm Quantitative analysis of aberrant p16 methylation using real-time quantitative methylation-specific polymerase chain reaction Cancer Res. 59 1999 3899 3903
    • (1999) Cancer Res. , vol.59 , pp. 3899-3903
    • Lo, Y.M.D.1    Wong, I.H.N.2    Zhang, J.3    Tein, M.S.C.4    Ng, M.H.L.5    Hjelm, N.M.6
  • 15
    • 0034746509 scopus 로고    scopus 로고
    • Hypermethylation of p16INK4A gene promoter during the progression of plasma cell dyscrasia
    • T. Uchida, T. Kinoshita, T. Ohno, H. Ohashi, H. Nagai, and H. Saito Hypermethylation of p16INK4A gene promoter during the progression of plasma cell dyscrasia Leukemia 15 2001 157 165
    • (2001) Leukemia , vol.15 , pp. 157-165
    • Uchida, T.1    Kinoshita, T.2    Ohno, T.3    Ohashi, H.4    Nagai, H.5    Saito, H.6
  • 18
    • 0033737604 scopus 로고    scopus 로고
    • Correlations of partial and extensive methylation at the p14 (ARF) locus with reduced mRNA expression in colorectal cancer cell lines and clinicopathological features in primary tumors
    • S. Zheng, P. Chen, A. McMillan, A. Lafuente, M.J. Lafuente, and A. Ballesta Correlations of partial and extensive methylation at the p14 (ARF) locus with reduced mRNA expression in colorectal cancer cell lines and clinicopathological features in primary tumors Carcinogenesis 21 2000 2057 2064
    • (2000) Carcinogenesis , vol.21 , pp. 2057-2064
    • Zheng, S.1    Chen, P.2    McMillan, A.3    Lafuente, A.4    Lafuente, M.J.5    Ballesta, A.6
  • 19
    • 0028116158 scopus 로고
    • Rapid silver staining and recovery of PCR products separated on polyacrylamide gels
    • C.J. Sanguinetti, E. Dias Neto, and A.J. Simpson Rapid silver staining and recovery of PCR products separated on polyacrylamide gels Biotechniques 17 1994 914 921
    • (1994) Biotechniques , vol.17 , pp. 914-921
    • Sanguinetti, C.J.1    Dias Neto, E.2    Simpson, A.J.3
  • 20
    • 0031839956 scopus 로고    scopus 로고
    • Homozygous deletions at chromosome 9p21 involving p16 and p15 are associated with histologic progression in follicle center lymphoma
    • K.S.J. Elenitoba-Johnson, R.D. Gascoyne, M.S. Lim, M. Chhanabai, E.S. Jaffe, and M. Raffeld Homozygous deletions at chromosome 9p21 involving p16 and p15 are associated with histologic progression in follicle center lymphoma Blood 91 1998 4677 4685
    • (1998) Blood , vol.91 , pp. 4677-4685
    • Elenitoba-Johnson, K.S.J.1    Gascoyne, R.D.2    Lim, M.S.3    Chhanabai, M.4    Jaffe, E.S.5    Raffeld, M.6
  • 22
    • 0041995063 scopus 로고    scopus 로고
    • Expression of angiogenic cytokines by plasma cells: A comparison of MGUS, smoldering myeloma and newly diagnosed symptomatic myeloma
    • S. Kumar, T.E. Witzig, M.A. Thompson, J. Haug, L. Wellik, and M.M. Timm Expression of angiogenic cytokines by plasma cells: a comparison of MGUS, smoldering myeloma and newly diagnosed symptomatic myeloma Blood 100 2002 807a
    • (2002) Blood , vol.100
    • Kumar, S.1    Witzig, T.E.2    Thompson, M.A.3    Haug, J.4    Wellik, L.5    Timm, M.M.6
  • 23
    • 0035207927 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor and its receptors in multiple myeloma and other hematopoietic malignancies
    • W.T. Bellamy Expression of vascular endothelial growth factor and its receptors in multiple myeloma and other hematopoietic malignancies Semin. Oncol. 28 2001 551 559
    • (2001) Semin. Oncol. , vol.28 , pp. 551-559
    • Bellamy, W.T.1
  • 24
    • 33845382806 scopus 로고
    • Nonparametric estimation from incomplete observations
    • E. Kaplan, and P. Meier Nonparametric estimation from incomplete observations J. Am. Stat. Assoc. 53 1958 457 481
    • (1958) J. Am. Stat. Assoc. , vol.53 , pp. 457-481
    • Kaplan, E.1    Meier, P.2
  • 25
    • 0030694727 scopus 로고    scopus 로고
    • Characterization of p16INK4A expression in multiple myeloma and plasma cell leukemia
    • M. Urashima, G. Teoh, A. Ogata, D. Chauhan, S.P. Treon, and Y. Sugimoto Characterization of p16INK4A expression in multiple myeloma and plasma cell leukemia Clin. Cancer Res. 3 1997 2173 2179
    • (1997) Clin. Cancer Res. , vol.3 , pp. 2173-2179
    • Urashima, M.1    Teoh, G.2    Ogata, A.3    Chauhan, D.4    Treon, S.P.5    Sugimoto, Y.6
  • 28
    • 0033778419 scopus 로고    scopus 로고
    • Status of methylation of p16 gene in multiple myeloma: A comparative study of three methods for its detection
    • M.V. Mateos, M. Gonzalez, A. Balanzategui, R. Lopez-Perez, D. Gonzalez, and M.C. Chillon Status of methylation of p16 gene in multiple myeloma: a comparative study of three methods for its detection Clin. Biochem. 33 2000 415 418
    • (2000) Clin. Biochem. , vol.33 , pp. 415-418
    • Mateos, M.V.1    Gonzalez, M.2    Balanzategui, A.3    Lopez-Perez, R.4    Gonzalez, D.5    Chillon, M.C.6
  • 29
    • 0032552020 scopus 로고    scopus 로고
    • P53 induces angiogenesis-restricted dormancy in a mouse fibrosarcoma
    • L. Holmgren, G. Jacksson, and J. Arbiser p53 induces angiogenesis- restricted dormancy in a mouse fibrosarcoma Oncogene 17 1998 819 824
    • (1998) Oncogene , vol.17 , pp. 819-824
    • Holmgren, L.1    Jacksson, G.2    Arbiser, J.3
  • 30
    • 0035863470 scopus 로고    scopus 로고
    • RB2/p130 gene-enhanced expression down-regulates vascular endothelial growth factor expression and inhibits angiogenesis in vivo
    • P.P. Claudio, P. Stiegler, C.M. Howard, C. Bellan, C. Minimo, and G.M. Tosi RB2/p130 gene-enhanced expression down-regulates vascular endothelial growth factor expression and inhibits angiogenesis in vivo Cancer Res. 61 2001 462 468
    • (2001) Cancer Res. , vol.61 , pp. 462-468
    • Claudio, P.P.1    Stiegler, P.2    Howard, C.M.3    Bellan, C.4    Minimo, C.5    Tosi, G.M.6
  • 31
    • 0037154738 scopus 로고    scopus 로고
    • Effect of p53 status on tumor response to antiangiogenic therapy
    • J.L. Yu, J.W. Rak, B.L. Coomber, D.J. Hicklin, and R.S. Kerbel Effect of p53 status on tumor response to antiangiogenic therapy Science 295 2002 1526 1528
    • (2002) Science , vol.295 , pp. 1526-1528
    • Yu, J.L.1    Rak, J.W.2    Coomber, B.L.3    Hicklin, D.J.4    Kerbel, R.S.5
  • 32
    • 0034652785 scopus 로고    scopus 로고
    • Increasing methylation of the CDKN2A gene is associated with the progression of adult T-cell leukemia
    • K. Nosaka, M. Maeda, S. Tamiya, T. Sakai, H. Mitsuya, and M. Matsuoka Increasing methylation of the CDKN2A gene is associated with the progression of adult T-cell leukemia Cancer Res. 60 2000 1043 1048
    • (2000) Cancer Res. , vol.60 , pp. 1043-1048
    • Nosaka, K.1    Maeda, M.2    Tamiya, S.3    Sakai, T.4    Mitsuya, H.5    Matsuoka, M.6
  • 33
    • 0032521402 scopus 로고    scopus 로고
    • The role of DNA methylation in expression of the p19/p16 locus in human bladder cancer cell lines
    • M.L. Gonzalgo, T. Hayashida, C.M. Bender, M.M. Pao, Y.C. Tasai, and F.A. Gonzales The role of DNA methylation in expression of the p19/p16 locus in human bladder cancer cell lines Cancer Res. 58 1998 1245 1252
    • (1998) Cancer Res. , vol.58 , pp. 1245-1252
    • Gonzalgo, M.L.1    Hayashida, T.2    Bender, C.M.3    Pao, M.M.4    Tasai, Y.C.5    Gonzales, F.A.6
  • 34
    • 0037108309 scopus 로고    scopus 로고
    • Demethylation of a hypermethylated P15/INK4B gene in patients with myelodysplastic syndrome by 5-Aza-2′-deoxycytidine (decitabine) treatment
    • M. Daskalakis, T.T. Nguyen, C. Nguyen, P. Guldberg, G. Kohler, and P. Wijermans Demethylation of a hypermethylated P15/INK4B gene in patients with myelodysplastic syndrome by 5-Aza-2′-deoxycytidine (decitabine) treatment Blood 100 2002 2957 2964
    • (2002) Blood , vol.100 , pp. 2957-2964
    • Daskalakis, M.1    Nguyen, T.T.2    Nguyen, C.3    Guldberg, P.4    Kohler, G.5    Wijermans, P.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.