Hypermethylation of p16INK4A gene promoter during the progression of plasma cell dyscrasia

Leukemia

Volumn 15, Issue 1, 2001, Pages 157-165

  Uchida, T ^a,b   Kinoshita, T ^a   Ohno, T ^a   Ohashi, H ^a   Nagai, H ^a   Saito, H ^a  

^a NAGOYA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b NAGOYA DAINI RED CROSS HOSPITAL   (Japan)

Author keywords

Disease progression; P15INK4B; P16INK4A; Plasma cell dyscrasia; Promoter hypermethylation; Tumor suppressor gene

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR; DNA; PROTEIN P15; PROTEIN P16; BIOLOGICAL MARKER; CARRIER PROTEIN; PROTEIN P16INK4A;

ADULT; AGED; ARTICLE; BONE MARROW CELL; CONTROLLED STUDY; CORRELATION FUNCTION; DISEASE COURSE; DNA METHYLATION; FEMALE; GENE ACTIVATION; GENE DELETION; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; MALE; MALIGNANT NEOPLASTIC DISEASE; MONONUCLEAR CELL; MULTIPLE MYELOMA; PLASMA CELL DYSCRASIA; PLASMACYTOMA; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION; SMEAR; TUMOR SUPPRESSOR GENE; GENETICS; PARAPROTEINEMIA; PATHOPHYSIOLOGY; PROGNOSIS;

BIOLOGICAL MARKERS; CARRIER PROTEINS; CYCLIN-DEPENDENT KINASE INHIBITOR P16; DNA METHYLATION; HUMANS; PARAPROTEINEMIAS; PROGNOSIS; PROMOTER REGIONS (GENETICS);

EID: 0034746509     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.leu.2401991     Document Type: Article

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