-
1
-
-
0035374653
-
Living dangerously: How Helicobacter pylori survives in the human stomach
-
Montecucco, C.; Rappuoli, R. Living dangerously: How Helicobacter pylori survives in the human stomach. Nat. Rev. Mol. Cell Biol. 2001, 2, 457-466.
-
(2001)
Nat. Rev. Mol. Cell Biol
, vol.2
, pp. 457-466
-
-
Montecucco, C.1
Rappuoli, R.2
-
2
-
-
0036370334
-
Helicobacter pylori and gastrointestinal tract adenocarcinomas
-
Peek, R.M.; Blaser, M.J. Helicobacter pylori and gastrointestinal tract adenocarcinomas. Nat. Rev. Cancer 2002, 2, 28-37.
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 28-37
-
-
Peek, R.M.1
Blaser, M.J.2
-
4
-
-
4444349432
-
Persistent bacterial infections: The interface of the pathogen and the host immune system
-
Monack, D.M.; Mueller, A.; Falkow, S. Persistent bacterial infections: The interface of the pathogen and the host immune system. Nat. Rev. Microbiol. 2004, 2, 747-765.
-
(2004)
Nat. Rev. Microbiol
, vol.2
, pp. 747-765
-
-
Monack, D.M.1
Mueller, A.2
Falkow, S.3
-
5
-
-
33746501942
-
Pathogenesis of Helicobacter pylori infection
-
Kusters, J.G.; van Vliet, A.H.; Kuipers, E.J. Pathogenesis of Helicobacter pylori infection. Clin. Microbiol. Rev. 2006, 19, 449-490.
-
(2006)
Clin. Microbiol. Rev
, vol.19
, pp. 449-490
-
-
Kusters, J.G.1
van Vliet, A.H.2
Kuipers, E.J.3
-
6
-
-
34547549860
-
Carcinogenesis of Helicobacter pylori
-
Correa, P.; Houghton, J. Carcinogenesis of Helicobacter pylori. Gastroenterology 2007, 133, 659-672.
-
(2007)
Gastroenterology
, vol.133
, pp. 659-672
-
-
Correa, P.1
Houghton, J.2
-
7
-
-
85047691456
-
Helicobacter pylori persistence: Biology and disease
-
Blaser, M.J.; Atherton, J.C. Helicobacter pylori persistence: Biology and disease. J. Clin. Invest. 2004, 113, 321-333.
-
(2004)
J. Clin. Invest
, vol.113
, pp. 321-333
-
-
Blaser, M.J.1
Atherton, J.C.2
-
8
-
-
15944418287
-
Helicobacter pylori VacA, a paradigm for toxin multifunctionality
-
Cover, T.L.; Blanke, S.R. Helicobacter pylori VacA, a paradigm for toxin multifunctionality. Nat. Rev. Microbiol. 2005, 3, 320-332.
-
(2005)
Nat. Rev. Microbiol
, vol.3
, pp. 320-332
-
-
Cover, T.L.1
Blanke, S.R.2
-
9
-
-
13444304088
-
Interaction of Helicobacter pylori with host cells: Function of secreted and translocated molecules
-
Rieder, G.; Fischer, W.; Haas, R. Interaction of Helicobacter pylori with host cells: Function of secreted and translocated molecules. Curr. Opin. Microbiol. 2005, 8, 67-73.
-
(2005)
Curr. Opin. Microbiol
, vol.8
, pp. 67-73
-
-
Rieder, G.1
Fischer, W.2
Haas, R.3
-
10
-
-
34447092208
-
Immunology of Helicobacter pylori: Insights into the failure of the immune response and perspectives on vaccine studies
-
Wilson, K.T.; Crabtree, J.E. Immunology of Helicobacter pylori: Insights into the failure of the immune response and perspectives on vaccine studies. Gastroenterology 2007, 133, 288-308.
-
(2007)
Gastroenterology
, vol.133
, pp. 288-308
-
-
Wilson, K.T.1
Crabtree, J.E.2
-
11
-
-
47549090077
-
Role of type IV secretion in Helicobacter pylori pathogenesis
-
Backert, S.; Selbach, M. Role of type IV secretion in Helicobacter pylori pathogenesis. Cell Microbiol. 2008, 10, 1573-1581.
-
(2008)
Cell Microbiol
, vol.10
, pp. 1573-1581
-
-
Backert, S.1
Selbach, M.2
-
12
-
-
37349009928
-
Host-bacterial interactions in Helicobacter pylori infection
-
Amieva, M.R.; El-Omar, E.M. Host-bacterial interactions in Helicobacter pylori infection. Gastroenterology 2008, 134, 306-323.
-
(2008)
Gastroenterology
, vol.134
, pp. 306-323
-
-
Amieva, M.R.1
El-Omar, E.M.2
-
13
-
-
0012218357
-
Disease-specific Helicobacter pylori virulence factors: The Unfulfilled Promise
-
Graham, D.Y.; Yamaoka, Y. Disease-specific Helicobacter pylori virulence factors: The unfulfilled promise. Helicobacter 2000, 5, 3-9.
-
(2000)
Helicobacter
, vol.5
, pp. 3-9
-
-
Graham, D.Y.1
Yamaoka, Y.2
-
14
-
-
9244245293
-
Nod1 responds to peptidoglycan delivered by the Helicobacter pylori cag pathogenicity island
-
Viala, J.; Chaput, C.; Boneca, I.G.; Cardona, A.; Girardin, S.E.; Moran, A.P.; Athman, R.; Mémet, S.; Huerre, M.R.; Coyle, A.J.; DiStefano, P.S.; Sansonetti, P.J.; Labigne, A.; Bertin, J.; Philpott, D.J.; Ferrero, R.L. Nod1 responds to peptidoglycan delivered by the Helicobacter pylori cag pathogenicity island. Nat. Immunol. 2004, 5, 1166-1174.
-
(2004)
Nat. Immunol
, vol.5
, pp. 1166-1174
-
-
Viala, J.1
Chaput, C.2
Boneca, I.G.3
Cardona, A.4
Girardin, S.E.5
Moran, A.P.6
Athman, R.7
Mémet, S.8
Huerre, M.R.9
Coyle, A.J.10
Distefano, P.S.11
Sansonetti, P.J.12
Labigne, A.13
Bertin, J.14
Philpott, D.J.15
Ferrero, R.L.16
-
15
-
-
34047250343
-
Helicobacter pylori is invasive and it may be a facultative intracellular organism
-
Dubois, A.; Borén, T. Helicobacter pylori is invasive and it may be a facultative intracellular organism. Cell. Microbiol. 2007, 9, 1108-1116.
-
(2007)
Cell. Microbiol
, vol.9
, pp. 1108-1116
-
-
Dubois, A.1
Borén, T.2
-
16
-
-
34249048365
-
Helicobacter pylori evolution and phenotypic diversification in a changing host
-
Suerbaum, S.; Josenhans, C. Helicobacter pylori evolution and phenotypic diversification in a changing host. Nat. Rev. Microbiol. 2007, 5, 441-452.
-
(2007)
Nat. Rev. Microbiol
, vol.5
, pp. 441-452
-
-
Suerbaum, S.1
Josenhans, C.2
-
17
-
-
0042825898
-
Gastric cell apoptosis and H. pylori: Has the main function of VacA finally been identified?
-
Boquet, P.; Ricci, V.; Galmiche, A.; Gauthier, N.C. Gastric cell apoptosis and H. pylori: Has the main function of VacA finally been identified? Trends Microbiol. 2003, 11, 410-413.
-
(2003)
Trends Microbiol
, vol.11
, pp. 410-413
-
-
Boquet, P.1
Ricci, V.2
Galmiche, A.3
Gauthier, N.C.4
-
18
-
-
33645865541
-
Secretion systems and their effectors in bacterial pathogenesis
-
Backert, S.; Meyer, T.F. Type IV secretion systems and their effectors in bacterial pathogenesis. Curr. Opin. Microbiol. 2006, 9, 207-217.
-
(2006)
Curr. Opin. Microbiol
, vol.9
, pp. 207-217
-
-
Backert, S.1
Meyer, T.F.2
Type, I.V.3
-
19
-
-
35349031591
-
Helicobacter exploits integrin for type IV secretion and kinase activation
-
Kwok, T.; Zabler, D.; Urman, S.; Rohde, M.; Hartig, R.; Wessler, S.; Misselwitz, R.; Berger, J.; Sewald, N.; König, W.; Backert, S. Helicobacter exploits integrin for type IV secretion and kinase activation. Nature 2007, 449, 862-866.
-
(2007)
Nature
, vol.449
, pp. 862-866
-
-
Kwok, T.1
Zabler, D.2
Urman, S.3
Rohde, M.4
Hartig, R.5
Wessler, S.6
Misselwitz, R.7
Berger, J.8
Sewald, N.9
König, W.10
Backert, S.11
-
20
-
-
40849085080
-
SagA of CagA in Helicobacter pylori pathogenesis
-
Hatakeyama, M. SagA of CagA in Helicobacter pylori pathogenesis. Curr. Opin. Microbiol. 2008, 11, 30-37.
-
(2008)
Curr. Opin. Microbiol
, vol.11
, pp. 30-37
-
-
Hatakeyama, M.1
-
21
-
-
21544441173
-
NF-B activation and potentiation of proinflammatory responses by the Helicobacter pylori CagA protein
-
Brandt, S.; Kwok, T.; Hartig, R.; König, W.; Backert, S. NF-B activation and potentiation of proinflammatory responses by the Helicobacter pylori CagA protein. Proc. Natl. Acad. Sci. USA 2005, 102, 9300-9305.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 9300-9305
-
-
Brandt, S.1
Kwok, T.2
Hartig, R.3
König, W.4
Backert, S.5
-
22
-
-
34848863375
-
Helicobacter pylori dampens gut epithelial selfrenewal by inhibiting apoptosis, a bacterial strategy to enhance colonization of the stomach
-
Mimuro, H.; Suzuki, T.; Nagai, S.; Rieder, G.; Suzuki, M.; Nagai, T.; Fujita, Y.; Nagamatsu, K.; Ishijima, N.; Koyasu, S.; Haas, R.; Sasakawa, C. Helicobacter pylori dampens gut epithelial selfrenewal by inhibiting apoptosis, a bacterial strategy to enhance colonization of the stomach. Cell Host Microbe 2007, 2, 250-263.
-
(2007)
Cell Host Microbe
, vol.2
, pp. 250-263
-
-
Mimuro, H.1
Suzuki, T.2
Nagai, S.3
Rieder, G.4
Suzuki, M.5
Nagai, T.6
Fujita, Y.7
Nagamatsu, K.8
Ishijima, N.9
Koyasu, S.10
Haas, R.11
Sasakawa, C.12
-
23
-
-
64649100982
-
Host cell interactome of tyrosine-phosphorylated bacterial proteins
-
Selbach, M.; Paul, F.E.; Brandt, S.; Guye, P.; Daumke, O.; Backert, S.; Dehio, C.; Mann, M. Host cell interactome of tyrosine-phosphorylated bacterial proteins. Cell Host Microbe 2009, 5, 397-403.
-
(2009)
Cell Host Microbe
, vol.5
, pp. 397-403
-
-
Selbach, M.1
Paul, F.E.2
Brandt, S.3
Guye, P.4
Daumke, O.5
Backert, S.6
Dehio, C.7
Mann, M.8
-
24
-
-
0035930508
-
Cag+Helicobacter pylori induce transactivation of the epidermal growth factor receptor in AGS gastric epithelial cells
-
Keates, S.; Sougioultzis, S.; Keates, A.C.; Zhao, D.; Peek, R.M.; Shaw, L.M.; Kelly, C.P. cag+Helicobacter pylori induce transactivation of the epidermal growth factor receptor in AGS gastric epithelial cells. J. Biol. Chem. 2001, 276, 48127-48134.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 48127-48134
-
-
Keates, S.1
Sougioultzis, S.2
Keates, A.C.3
Zhao, D.4
Peek, R.M.5
Shaw, L.M.6
Kelly, C.P.7
-
25
-
-
0036313948
-
Helicobacter pylori-stimulated EGF receptor transactivation requires metalloprotease cleavage of HB-EGF
-
Wallasch, C.; Crabtree, J.E.; Bevec, D.; Robinson, P.A.; Wagner, H.; Ullrich, A. Helicobacter pylori-stimulated EGF receptor transactivation requires metalloprotease cleavage of HB-EGF. Biochem. Biophys. Res. Commun. 2002, 29, 695-701.
-
(2002)
Biochem. Biophys. Res. Commun
, vol.29
, pp. 695-701
-
-
Wallasch, C.1
Crabtree, J.E.2
Bevec, D.3
Robinson, P.A.4
Wagner, H.5
Ullrich, A.6
-
26
-
-
0035004343
-
Pathogenicity island-dependent activation of Rho GTPases Rac1 and Cdc42 in Helicobacter pylori infection
-
Churin, Y.; Kardalinou, E.; Meyer, T.F.; Naumann, M. Pathogenicity island-dependent activation of Rho GTPases Rac1 and Cdc42 in Helicobacter pylori infection. Mol. Microbiol. 2001, 40, 815-823.
-
(2001)
Mol. Microbiol
, vol.40
, pp. 815-823
-
-
Churin, Y.1
Kardalinou, E.2
Meyer, T.F.3
Naumann, M.4
-
27
-
-
27744471043
-
Interaction of CagA-Crk plays an important role in Helicobacter pylori-induced loss of gastric epithelial cell adhesion
-
Suzuki, M.; Mimuro, H.; Suzuki, T.; Park, M.; Yamamoto, T.; Sasakawa, C. Interaction of CagA-Crk plays an important role in Helicobacter pylori-induced loss of gastric epithelial cell adhesion. J. Exp. Med. 2005, 202, 1235-1247.
-
(2005)
J. Exp. Med
, vol.202
, pp. 1235-1247
-
-
Suzuki, M.1
Mimuro, H.2
Suzuki, T.3
Park, M.4
Yamamoto, T.5
Sasakawa, C.6
-
28
-
-
34250370846
-
Use of a novel coinfection system reveals a role for Rac1, H-Ras, and CrkII phosphorylation in Helicobacter pylori-induced host cell actin cytoskeletal rearrangements
-
Brandt, S.; Shafikhani, S.; Balachandran, P.; Jin, S.; Hartig, R.; König, W.; Engel, J.; Backert, S. Use of a novel coinfection system reveals a role for Rac1, H-Ras, and CrkII phosphorylation in Helicobacter pylori-induced host cell actin cytoskeletal rearrangements. FEMS Immunol. Med. Microbiol. 2007, 50, 190-205.
-
(2007)
FEMS Immunol. Med. Microbiol
, vol.50
, pp. 190-205
-
-
Brandt, S.1
Shafikhani, S.2
Balachandran, P.3
Jin, S.4
Hartig, R.5
König, W.6
Engel, J.7
Backert, S.8
-
29
-
-
0023912268
-
Cytotoxic activity in brothculture filtrates of Campylobacter pylori
-
Leunk, R.D.; Johnson, P.T.; David, B.C.; Kraft, W.G.; Morgan, D.R. Cytotoxic activity in brothculture filtrates of Campylobacter pylori. J. Med. Microbiol. 1988, 26, 93-99.
-
(1988)
J. Med. Microbiol
, vol.26
, pp. 93-99
-
-
Leunk, R.D.1
Johnson, P.T.2
David, B.C.3
Kraft, W.G.4
Morgan, D.R.5
-
30
-
-
0036089516
-
Proteome analysis of secreted proteins of the gastric pathogen Helicobacter pylori
-
Bumann, D.; Aksu, S.; Wendland, M.; Janek, K.; Zimny-Arndt, U.; Sabarth, N.; Meyer, T.F.; Jungblut, P.R. Proteome analysis of secreted proteins of the gastric pathogen Helicobacter pylori. Infect. Immun. 2002, 70, 3396-3403.
-
(2002)
Infect. Immun
, vol.70
, pp. 3396-3403
-
-
Bumann, D.1
Aksu, S.2
Wendland, M.3
Janek, K.4
Zimny-Arndt, U.5
Sabarth, N.6
Meyer, T.F.7
Jungblut, P.R.8
-
31
-
-
17044389822
-
Subproteomes of soluble and structure-bound Helicobacter pylori proteins analyzed by two-dimensional gel electrophoresis and mass spectrometry
-
Backert, S.; Kwok, T.; Schmid, M.; Selbach, M.; Moese, S.; Peek, R.M.; König, W.; Meyer, T.F.; Jungblut, P.R. Subproteomes of soluble and structure-bound Helicobacter pylori proteins analyzed by two-dimensional gel electrophoresis and mass spectrometry. Proteomics 2005, 5, 1331-1345.
-
(2005)
Proteomics
, vol.5
, pp. 1331-1345
-
-
Backert, S.1
Kwok, T.2
Schmid, M.3
Selbach, M.4
Moese, S.5
Peek, R.M.6
König, W.7
Meyer, T.F.8
Jungblut, P.R.9
-
32
-
-
0028355422
-
Gene structure of the Helicobacter pylori cytotoxin and evidence of its key role in gastric disease
-
Telford, J.L.; Ghiara, P.; Dell'Orco, M.; Comanducci, M.; Burroni, D.; Bugnoli, M.; Tecce, M.F.; Censini, S.; Covacci, A.; Xiang, Z. Gene structure of the Helicobacter pylori cytotoxin and evidence of its key role in gastric disease. J. Exp. Med. 1994, 179, 1653-1658.
-
(1994)
J. Exp. Med
, vol.179
, pp. 1653-1658
-
-
Telford, J.L.1
Ghiara, P.2
Dell'orco, M.3
Comanducci, M.4
Burroni, D.5
Bugnoli, M.6
Tecce, M.F.7
Censini, S.8
Covacci, A.9
Xiang, Z.10
-
33
-
-
0029898566
-
Oligomeric and subunit structure of the Helicobacter pylori vacuolating cytotoxin
-
Lupetti, P.; Heuser, J.E.; Manetti, R.; Massari, P.; Lanzavecchia, S.; Bellon, P.L.; Dallai, R.; Rappuoli, R.; Telford, J.L. Oligomeric and subunit structure of the Helicobacter pylori vacuolating cytotoxin. J. Cell Biol. 1996, 133, 801-807.
-
(1996)
J. Cell Biol
, vol.133
, pp. 801-807
-
-
Lupetti, P.1
Heuser, J.E.2
Manetti, R.3
Massari, P.4
Lanzavecchia, S.5
Bellon, P.L.6
Dallai, R.7
Rappuoli, R.8
Telford, J.L.9
-
34
-
-
0030663325
-
Helicobacter pylori vacuolating toxin accumulates within the endosomal-vacuolar compartment of cultured gastric cells and potentiates the vacuolating activity of ammonia
-
Ricci, V.; Sommi, P.; Fiocca, R.; Romano, M.; Solcia, E.; Ventura, U. Helicobacter pylori vacuolating toxin accumulates within the endosomal-vacuolar compartment of cultured gastric cells and potentiates the vacuolating activity of ammonia. J. Pathol. 1997, 183, 453-459.
-
(1997)
J. Pathol
, vol.183
, pp. 453-459
-
-
Ricci, V.1
Sommi, P.2
Fiocca, R.3
Romano, M.4
Solcia, E.5
Ventura, U.6
-
35
-
-
34548495047
-
A new Helicobacter pylori vacuolating cytotoxin determinant, the intermediate region, is associated with gastric cancer
-
Rhead, J.L.; Letley, D.P.; Mohammadi, M.; Hussein, N.; Mohagheghi, M.A.; Eshagh Hosseini, M.; Atherton, J.C. A new Helicobacter pylori vacuolating cytotoxin determinant, the intermediate region, is associated with gastric cancer. Gastroenterology 2007, 133, 926-936.
-
(2007)
Gastroenterology
, vol.133
, pp. 926-936
-
-
Rhead, J.L.1
Letley, D.P.2
Mohammadi, M.3
Hussein, N.4
Mohagheghi, M.A.5
Eshagh, H.M.6
Atherton, J.C.7
-
36
-
-
13144253096
-
The m2 form of the Helicobacter pylori cytotoxin has cell typespecific vacuolating activity
-
Pagliaccia, C.; de Bernard, M.; Lupetti, P.; Ji, X.; Burroni, D.; Cover, T.L.; Papini, E.; Rappuoli, R.; Telford, J.L.; Reyrat, J.M. The m2 form of the Helicobacter pylori cytotoxin has cell typespecific vacuolating activity. Proc. Natl. Acad. Sci. USA 1998, 95, 10212-10217.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 10212-10217
-
-
Pagliaccia, C.1
de Bernard, M.2
Lupetti, P.3
Ji, X.4
Burroni, D.5
Cover, T.L.6
Papini, E.7
Rappuoli, R.8
Telford, J.L.9
Reyrat, J.M.10
-
37
-
-
0033538416
-
3D imaging of the 58 kDa cell binding subunit of the Helicobacter pylori cytotoxin
-
Reyrat, J.M.; Lanzavecchia, S.; Lupetti, P.; de Bernard, M.; Pagliaccia, C.; Pelicic, V.; Charrel, M.; Ulivieri, C.; Norais, N.; Ji, X.; Cabiaux, V.; Papini, E.; Rappuoli, R.; Telford, J.L. 3D imaging of the 58 kDa cell binding subunit of the Helicobacter pylori cytotoxin. J. Mol. Biol. 1999, 290, 459-470.
-
(1999)
J. Mol. Biol
, vol.290
, pp. 459-470
-
-
Reyrat, J.M.1
Lanzavecchia, S.2
Lupetti, P.3
de Bernard, M.4
Pagliaccia, C.5
Pelicic, V.6
Charrel, M.7
Ulivieri, C.8
Norais, N.9
Ji, X.10
Cabiaux, V.11
Papini, E.12
Rappuoli, R.13
Telford, J.L.14
-
38
-
-
0028818757
-
Low pH activates the vacuolating toxin of Helicobacter pylori, which becomes acid and pepsin resistant
-
de Bernard, M.; Papini, E.; de Filippis, V.; Gottardi, E.; Telford, J.; Manetti, R.; Fontana, A.; Rappuoli, R.; Montecucco, C. Low pH activates the vacuolating toxin of Helicobacter pylori, which becomes acid and pepsin resistant. J. Biol.Chem. 1995, 270, 23937-23940.
-
(1995)
J. Biol.Chem
, vol.270
, pp. 23937-23940
-
-
de Bernard, M.1
Papini, E.2
de Filippis, V.3
Gottardi, E.4
Telford, J.5
Manetti, R.6
Fontana, A.7
Rappuoli, R.8
Montecucco, C.9
-
39
-
-
0033579575
-
Activation of Helicobacter pylori VacA toxin by alkaline or acid conditions increases its binding to a 250-kDa receptor protein-tyrosine phosphatase β
-
Yahiro, K.; Niidome, T.; Kimura, M.; Hatakeyama, T.; Aoyagi, H.; Kurazono, H.; Imagawa, K.; Wada, A.; Moss, J.; Hirayama, T. Activation of Helicobacter pylori VacA toxin by alkaline or acid conditions increases its binding to a 250-kDa receptor protein-tyrosine phosphatase β. J. Biol. Chem. 1999, 274, 36693-36699.
-
(1999)
J. Biol. Chem
, vol.274
, pp. 36693-36699
-
-
Yahiro, K.1
Niidome, T.2
Kimura, M.3
Hatakeyama, T.4
Aoyagi, H.5
Kurazono, H.6
Imagawa, K.7
Wada, A.8
Moss, J.9
Hirayama, T.10
-
40
-
-
0030809535
-
Acid-induced dissociation of VacA, the Helicobacter pylori vacuolating cytotoxin, reveals its pattern of assembly
-
Cover, T.L.; Hanson, P.I.; Heuser, J.E. Acid-induced dissociation of VacA, the Helicobacter pylori vacuolating cytotoxin, reveals its pattern of assembly. J. Cell Biol. 1997, 138, 759-769.
-
(1997)
J. Cell Biol
, vol.138
, pp. 759-769
-
-
Cover, T.L.1
Hanson, P.I.2
Heuser, J.E.3
-
41
-
-
0033515072
-
The vacuolating toxin from Helicobacter pylori forms hexameric pores in lipid bilayers at low pH
-
Czajkowsky, D.M.; Iwamoto, H.; Cover, T.L.; Shao, Z. The vacuolating toxin from Helicobacter pylori forms hexameric pores in lipid bilayers at low pH. Proc. Natl. Acad. Sci. USA 1999, 96, 2001-2006.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 2001-2006
-
-
Czajkowsky, D.M.1
Iwamoto, H.2
Cover, T.L.3
Shao, Z.4
-
42
-
-
0032981962
-
Helicobacter pylori vacuolating toxin forms anionselective channels in planar lipid bilayers: Possible implications for the mechanism of cellular vacuolation
-
Tombola, F.: Carlesso, C.; Szabó, I.; de Bernard, M.; Reyrat, J.M.; Telford, J.L.; Rappuoli, R.; Montecucco, C.; Papini, E.; Zoratti, M. Helicobacter pylori vacuolating toxin forms anionselective channels in planar lipid bilayers: Possible implications for the mechanism of cellular vacuolation. Biophys. J. 1999, 76, 1401-1409.
-
(1999)
Biophys. J
, vol.76
, pp. 1401-1409
-
-
Tombola, F.1
Carlesso, C.2
Szabó, I.3
de Bernard, M.4
Reyrat, J.M.5
Telford, J.L.6
Rappuoli, R.7
Montecucco, C.8
Papini, E.9
Zoratti, M.10
-
43
-
-
0033007098
-
VacA from Helicobacter pylori: A hexameric chloride channel
-
Iwamoto, H.; Czajkowsky, D.M.; Cover, T.L.; Szabo, G.; Shao, Z. VacA from Helicobacter pylori: A hexameric chloride channel. FEBS Lett. 1999, 450, 101-104.
-
(1999)
FEBS Lett
, vol.450
, pp. 101-104
-
-
Iwamoto, H.1
Czajkowsky, D.M.2
Cover, T.L.3
Szabo, G.4
Shao, Z.5
-
44
-
-
25144442682
-
High resolution structural analysis of Helicobacter pylori VacA toxin oligomers by cryo-negative staining electron microscopy
-
El-Bez, C.; Adrian, M.; Dubochet, J.; Cover, T.L. High resolution structural analysis of Helicobacter pylori VacA toxin oligomers by cryo-negative staining electron microscopy. J. Struct. Biol. 2005, 151, 215-228.
-
(2005)
J. Struct. Biol
, vol.151
, pp. 215-228
-
-
El-Bez, C.1
Adrian, M.2
Dubochet, J.3
Cover, T.L.4
-
45
-
-
0033515453
-
Identification of the minimal intracellular vacuolating domain of the Helicobacter pylori vacuolating toxin
-
Ye, D.; Willhite, D.C.; Blanke, S.R. Identification of the minimal intracellular vacuolating domain of the Helicobacter pylori vacuolating toxin. J. Biol. Chem. 1999, 274, 9277-9282.
-
(1999)
J. Biol. Chem
, vol.274
, pp. 9277-9282
-
-
Ye, D.1
Willhite, D.C.2
Blanke, S.R.3
-
46
-
-
0346457086
-
Interactions between p-33 and p-55 domains of the Helicobacter pylori vacuolating cytotoxin (VacA)
-
Torres, V.J.; McClain, M.S.; Cover, T.L. Interactions between p-33 and p-55 domains of the Helicobacter pylori vacuolating cytotoxin (VacA). J. Biol. Chem. 2004, 279, 2324-2331.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 2324-2331
-
-
Torres, V.J.1
McClain, M.S.2
Cover, T.L.3
-
47
-
-
20444426199
-
Functional properties of the p33 and p55 domains of the Helicobacter pylori vacuolating cytotoxin
-
Torres, V.J.; Ivie, S.E.; McClain, M.S.; Cover, T.L. Functional properties of the p33 and p55 domains of the Helicobacter pylori vacuolating cytotoxin. J. Biol. Chem. 2005, 280, 21107-21114.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 21107-21114
-
-
Torres, V.J.1
Ivie, S.E.2
McClain, M.S.3
Cover, T.L.4
-
48
-
-
0033621333
-
Dominant negative mutant of Helicobacter pylori vacuolating toxin (VacA) inhibits VacA-induced cell vacuolation
-
Vinion-Dubiel, A.D.; McClain, M.S.; Czajkowsky, D.M.; Iwamoto, H.; Ye, D.; Cao, P.; Schraw, W.; Szabo, G.; Blanke, S.R.; Shao, Z.; Cover, T.L. A dominant negative mutant of Helicobacter pylori vacuolating toxin (VacA) inhibits VacA-induced cell vacuolation. J. Biol. Chem. 1999, 274, 37736-37742.
-
(1999)
J. Biol. Chem
, vol.274
, pp. 37736-37742
-
-
Vinion-Dubiel, A.D.1
McClain, M.S.2
Czajkowsky, D.M.3
Iwamoto, H.4
Ye, D.5
Cao, P.6
Schraw, W.7
Szabo, G.8
Blanke, S.R.9
Shao, Z.10
Cover, T.L.A.11
-
49
-
-
0037561932
-
Essential role of a GXXXG motif for membrane channel formation by Helicobacter pylori vacuolating toxin
-
McClain, M.S.; Iwamoto, H.; Cao, P.; Vinion-Dubiel, A.D.; Li, Y.; Szabo, G.; Shao, Z.; Cover, T.L. Essential role of a GXXXG motif for membrane channel formation by Helicobacter pylori vacuolating toxin. J. Biol. Chem. 2003, 278, 12101-12108.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 12101-12108
-
-
McClain, M.S.1
Iwamoto, H.2
Cao, P.3
Vinion-Dubiel, A.D.4
Li, Y.5
Szabo, G.6
Shao, Z.7
Cover, T.L.8
-
50
-
-
0034687542
-
Expression and binding analysis of GST-VacA fusions reveals that the C-terminal approximately 100-residue segment of exotoxin is crucial for binding in HeLa cells. Biochem. Biophys
-
Wang, H.J.; Wang, W.C. Expression and binding analysis of GST-VacA fusions reveals that the C-terminal approximately 100-residue segment of exotoxin is crucial for binding in HeLa cells. Biochem. Biophys. Res. Commun. 2000, 278, 449-454.
-
(2000)
Res. Commun
, vol.278
, pp. 449-454
-
-
Wang, H.J.1
Wang, W.C.2
-
51
-
-
36048946721
-
Crystal structure of the Helicobacter pylori vacuolating toxin p55 domain
-
Gangwer, K.A.; Mushrush, D.J.; Stauff, D.L.; Spiller, B.; McClain, M.S.; Cover, T.L.; Lacy, D.B. Crystal structure of the Helicobacter pylori vacuolating toxin p55 domain. Proc. Natl. Acad. Sci. USA 2007, 104, 16293-16298.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 16293-16298
-
-
Gangwer, K.A.1
Mushrush, D.J.2
Stauff, D.L.3
Spiller, B.4
McClain, M.S.5
Cover, T.L.6
Lacy, D.B.7
-
52
-
-
0033748047
-
High cell sensitivity to Helicobacter pylori VacA toxin depends on a GPI-anchored protein and is not blocked by inhibition of the clathrin-mediated pathway of endocytosis
-
Ricci, V.; Galmiche, A.; Doye, A.; Necchi, V.; Solcia, E.; Boquet, P. High cell sensitivity to Helicobacter pylori VacA toxin depends on a GPI-anchored protein and is not blocked by inhibition of the clathrin-mediated pathway of endocytosis. Mol. Biol. Cell. 2000, 11, 3897-3909.
-
(2000)
Mol. Biol. Cell
, vol.11
, pp. 3897-3909
-
-
Ricci, V.1
Galmiche, A.2
Doye, A.3
Necchi, V.4
Solcia, E.5
Boquet, P.6
-
53
-
-
26244459823
-
Helicobacter pylori VacA cytotoxin: A probe for a clathrin-independent and Cdc42-dependent pinocytic pathway routed to late endosomes
-
Gauthier, N.C.; Monzo, P.; Kaddai, V.; Doye, A.; Ricci, V.; Boquet, P. Helicobacter pylori VacA cytotoxin: A probe for a clathrin-independent and Cdc42-dependent pinocytic pathway routed to late endosomes. Mol. Biol. Cell. 2005, 16, 4852-4866.
-
(2005)
Mol. Biol. Cell
, vol.16
, pp. 4852-4866
-
-
Gauthier, N.C.1
Monzo, P.2
Kaddai, V.3
Doye, A.4
Ricci, V.5
Boquet, P.6
-
54
-
-
0038482093
-
Protein-tyrosine phosphatase alpha, RPTPα, is a Helicobacter pylori VacA receptor
-
Yahiro, K.; Wada, A.; Nakayama, M.; Kimura, T.; Ogushi, K.; Niidome, T.; Aoyagi, H.; Yoshino, K.; Yonezawa, K.; Moss, J.; Hirayama, T. Protein-tyrosine phosphatase alpha, RPTPα, is a Helicobacter pylori VacA receptor. J. Biol. Chem. 2003, 278, 19183-19189.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 19183-19189
-
-
Yahiro, K.1
Wada, A.2
Nakayama, M.3
Kimura, T.4
Ogushi, K.5
Niidome, T.6
Aoyagi, H.7
Yoshino, K.8
Yonezawa, K.9
Moss, J.10
Hirayama, T.11
-
55
-
-
0037370481
-
Mice deficient in protein tyrosine phosphatase receptor type Z are resistant to gastric ulcer induction by VacA of Helicobacter pylori
-
Fujikawa, A.; Shirasaka, D.; Yamamoto, S.; Ota, H.; Yahiro, K.; Fukada, M.; Shintani, T.; Wada, A.; Aoyama, N.; Hirayama, T.; Fukamachi, H.; Noda, M. Mice deficient in protein tyrosine phosphatase receptor type Z are resistant to gastric ulcer induction by VacA of Helicobacter pylori. Nat. Genet. 2003, 33, 375-381.
-
(2003)
Nat. Genet
, vol.33
, pp. 375-381
-
-
Fujikawa, A.1
Shirasaka, D.2
Yamamoto, S.3
Ota, H.4
Yahiro, K.5
Fukada, M.6
Shintani, T.7
Wada, A.8
Aoyama, N.9
Hirayama, T.10
Fukamachi, H.11
Noda, M.12
-
56
-
-
0029559119
-
Lipid interaction of the 37-kDa and 58-kDa fragments of the Helicobacter pylori cytotoxin
-
Moll, G.; Papini, E.; Colonna, R.; Burroni, D.; Telford, J.; Rappuoli, R.; Montecucco, C. Lipid interaction of the 37-kDa and 58-kDa fragments of the Helicobacter pylori cytotoxin. Eur. J. Biochem. 1995, 234, 947-952.
-
(1995)
Eur. J. Biochem
, vol.234
, pp. 947-952
-
-
Moll, G.1
Papini, E.2
Colonna, R.3
Burroni, D.4
Telford, J.5
Rappuoli, R.6
Montecucco, C.7
-
57
-
-
0032551711
-
The acid activation of Helicobacter pylori toxin VacA: Structural and membrane binding studies
-
Molinari, M.; Galli, C.; de Bernard, M.; Norais, N.; Ruysschaert, J.M.; Rappuoli, R.; Montecucco, C. The acid activation of Helicobacter pylori toxin VacA: Structural and membrane binding studies. Biochem. Biophys. Res. Commun. 1998, 248, 334-340.
-
(1998)
Biochem. Biophys. Res. Commun
, vol.248
, pp. 334-340
-
-
Molinari, M.1
Galli, C.2
de Bernard, M.3
Norais, N.4
Ruysschaert, J.M.5
Rappuoli, R.6
Montecucco, C.7
-
58
-
-
0035068436
-
Helicobacter pylori vacuolating cytotoxin binding to a putative cell surface receptor, heparan sulfate, studied by surface plasmon resonance
-
Utt, M.; Danielsson, B.; Wadström, T. Helicobacter pylori vacuolating cytotoxin binding to a putative cell surface receptor, heparan sulfate, studied by surface plasmon resonance. FEMS Immunol. Med. Microbiol. 2001, 30, 109-113.
-
(2001)
FEMS Immunol. Med. Microbiol
, vol.30
, pp. 109-113
-
-
Utt, M.1
Danielsson, B.2
Wadström, T.3
-
59
-
-
44949199208
-
Sphingomyelin functions as a novel receptor for Helicobacter pylori VacA
-
doi:10.1371/journal.ppat.1000073
-
Gupta, V.R.; Patel, H.K.; Kostolansky, S.S.; Ballivian, R.A.; Eichberg, J.; Blanke, S.R. Sphingomyelin functions as a novel receptor for Helicobacter pylori VacA. PLoS Pathog. 2008, 4, doi:10.1371/journal.ppat.1000073.
-
(2008)
PLoS Pathog
, vol.4
-
-
Gupta, V.R.1
Patel, H.K.2
Kostolansky, S.S.3
Ballivian, R.A.4
Eichberg, J.5
Blanke, S.R.6
-
60
-
-
24344483178
-
Helicobacter pylori VacA cytotoxin interacts with fibronectin and alters HeLa cell adhesion and cytoskeletal organization in vitro
-
Hennig, E.E.; Godlewski, M.M.; Butruk, E.; Ostrowski, J. Helicobacter pylori VacA cytotoxin interacts with fibronectin and alters HeLa cell adhesion and cytoskeletal organization in vitro. FEMS Immunol. Med. Microbiol. 2005, 44, 143-150.
-
(2005)
FEMS Immunol. Med. Microbiol
, vol.44
, pp. 143-150
-
-
Hennig, E.E.1
Godlewski, M.M.2
Butruk, E.3
Ostrowski, J.4
-
61
-
-
0032563331
-
Vacuolation induced by cytotoxin from Helicobacter pylori is mediated by the EGF receptor in HeLa cells
-
Seto, K.; Hayashi-Kuwabara, Y.; Yoneta, T.; Suda, H.; Tamaki, H. Vacuolation induced by cytotoxin from Helicobacter pylori is mediated by the EGF receptor in HeLa cells. FEBS Lett. 1998, 431, 347-350.
-
(1998)
FEBS Lett
, vol.431
, pp. 347-350
-
-
Seto, K.1
Hayashi-Kuwabara, Y.2
Yoneta, T.3
Suda, H.4
Tamaki, H.5
-
62
-
-
38049042859
-
Integrin subunit CD18 Is the T-lymphocyte receptor for the Helicobacter pylori vacuolating cytotoxin
-
Sewald, X.; Gebert-Vogl, B.; Prassl, S.; Barwig, I.; Weiss, E.; Fabbri, M.; Osicka, R.; Schiemann, M.; Busch, D.H.; Semmrich, M.; Holzmann, B.; Sebo, P.; Haas, R. Integrin subunit CD18 Is the T-lymphocyte receptor for the Helicobacter pylori vacuolating cytotoxin. Cell Host Microbe 2008, 3, 20-29.
-
(2008)
Cell Host Microbe
, vol.3
, pp. 20-29
-
-
Sewald, X.1
Gebert-Vogl, B.2
Prassl, S.3
Barwig, I.4
Weiss, E.5
Fabbri, M.6
Osicka, R.7
Schiemann, M.8
Busch, D.H.9
Semmrich, M.10
Holzmann, B.11
Sebo, P.12
Haas, R.13
-
63
-
-
0034686079
-
Morphologic differentiation of HL-60 cells is associated with appearance of RPTPβ and induction of Helicobacter pylori VacA sensitivity
-
Padilla, P.I.; Wada, A.; Yahiro, K.; Kimura, M.; Niidome, T.; Aoyagi, H.; Kumatori, A.; Anami, M.; Hayashi, T.; Fujisawa, J.; Saito, H.; Moss, J.; Hirayama, T. Morphologic differentiation of HL-60 cells is associated with appearance of RPTPβ and induction of Helicobacter pylori VacA sensitivity. J. Biol. Chem. 2000, 275, 15200-15206.
-
(2000)
J. Biol. Chem
, vol.275
, pp. 15200-15206
-
-
Padilla, P.I.1
Wada, A.2
Yahiro, K.3
Kimura, M.4
Niidome, T.5
Aoyagi, H.6
Kumatori, A.7
Anami, M.8
Hayashi, T.9
Fujisawa, J.10
Saito, H.11
Moss, J.12
Hirayama, T.13
-
64
-
-
33845503473
-
Clustering of Helicobacter pylori VacA in lipid rafts, mediated by its receptor, receptor-like protein tyrosine phosphatase β, is required for intoxication in AZ-521 Cells
-
Nakayama, M.; Hisatsune, J.; Yamasaki, E.; Nishi, Y.; Wada, A.; Kurazono, H.; Sap, J.; Yahiro, K.; Moss, J.; Hirayama, T. Clustering of Helicobacter pylori VacA in lipid rafts, mediated by its receptor, receptor-like protein tyrosine phosphatase β, is required for intoxication in AZ-521 Cells. Infect. Immun. 2006, 74, 6571-6580.
-
(2006)
Infect. Immun
, vol.74
, pp. 6571-6580
-
-
Nakayama, M.1
Hisatsune, J.2
Yamasaki, E.3
Nishi, Y.4
Wada, A.5
Kurazono, H.6
Sap, J.7
Yahiro, K.8
Moss, J.9
Hirayama, T.10
-
65
-
-
34247376586
-
Human gastric glycosphingolipids recognized by Helicobacter pylori vacuolating cytotoxin VacA
-
Roche, N.; Ilver, D.; Angstrom, J.; Barone, S.; Telford, J.L.; Teneberg, S. Human gastric glycosphingolipids recognized by Helicobacter pylori vacuolating cytotoxin VacA. Microbes Infect. 2007, 9, 605-614.
-
(2007)
Microbes Infect
, vol.9
, pp. 605-614
-
-
Roche, N.1
Ilver, D.2
Angstrom, J.3
Barone, S.4
Telford, J.L.5
Teneberg, S.6
-
66
-
-
0037072947
-
Association of Helicobacter pylori vacuolating toxin (VacA) with lipid rafts
-
Schraw, W.; Li, Y.; McClain, M.S.; van der Goot, F.G.; Cover, T.L. Association of Helicobacter pylori vacuolating toxin (VacA) with lipid rafts. J. Biol. Chem. 2002, 277, 34642-34650.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 34642-34650
-
-
Schraw, W.1
Li, Y.2
McClain, M.S.3
van der, G.F.G.4
Cover, T.L.5
-
67
-
-
0037418698
-
Binding and internalization of Helicobacter pylori VacA via ellular lipid rafts in epithelial cells
-
Kuo, C.H.; Wang, W.C. Binding and internalization of Helicobacter pylori VacA via ellular lipid rafts in epithelial cells. Biochem. Biophys. Res. Commun. 2003, 303, 640-644.
-
(2003)
Biochem. Biophys. Res. Commun
, vol.303
, pp. 640-644
-
-
Kuo, C.H.1
Wang, W.C.2
-
68
-
-
23844511511
-
Cytotoxicity and recognition of receptor-like protein tyrosine phosphatases, RPTPα and RPTPβ, by Helicobacter pylori m2VacA
-
De Guzman, B.B.; Hisatsune, J.; Nakayama, M.; Yahiro, K.; Wada, A.; Yamasaki, E.; Nishi, Y.; Yamazaki, S.; Azuma, T.; Ito, Y.; Ohtani, M.; van der Wijk, T.; den Hertog, J.; Moss, J.; Hirayama, T. Cytotoxicity and recognition of receptor-like protein tyrosine phosphatases, RPTPα and RPTPβ, by Helicobacter pylori m2VacA. Cell. Microbiol. 2005, 7, 1285-1293.
-
(2005)
Cell. Microbiol
, vol.7
, pp. 1285-1293
-
-
De Guzman, B.B.1
Hisatsune, J.2
Nakayama, M.3
Yahiro, K.4
Wada, A.5
Yamasaki, E.6
Nishi, Y.7
Yamazaki, S.8
Azuma, T.9
Ito, Y.10
Ohtani, M.11
van der, W.T.12
den Hertog, J.13
Moss, J.14
Hirayama, T.15
-
69
-
-
0035940979
-
RACK1 protein interacts with Helicobacter pylori VacA cytotoxin: The yeast two-hybrid approach. Biochem
-
Hennig, E.E.; Butruk, E.; Ostrowski, J. RACK1 protein interacts with Helicobacter pylori VacA cytotoxin: The yeast two-hybrid approach. Biochem. Biophys. Res. Commun. 2001, 289, 103-110.
-
(2001)
Biophys. Res. Commun
, vol.289
, pp. 103-110
-
-
Hennig, E.E.1
Butruk, E.2
Ostrowski, J.3
-
70
-
-
0030868990
-
Vacuoles induced by Helicobacter pylori toxin contain both late endosomal and lysosomal markers
-
Molinari, M.; Galli, C.; Norais, N.; Telford, J.L.; Rappuoli, R.; Luzio, J.P.; Montecucco, C. Vacuoles induced by Helicobacter pylori toxin contain both late endosomal and lysosomal markers. J. Biol. Chem. 1997, 272, 25339-25344.
-
(1997)
J. Biol. Chem
, vol.272
, pp. 25339-25344
-
-
Molinari, M.1
Galli, C.2
Norais, N.3
Telford, J.L.4
Rappuoli, R.5
Luzio, J.P.6
Montecucco, C.7
-
71
-
-
34247528572
-
Early endosomes associated with dynamic F-actin structures are required for late trafficking of H
-
Gauthier, N.C.; Monzo, P.; Gonzalez, T.; Doye, A.; Oldani, A.; Gounon, P.; Ricci, V.; Cormont, M.; Boquet P. Early endosomes associated with dynamic F-actin structures are required for late trafficking of H. pylori VacA toxin. J. Cell Biol. 2007, 177, 343-354.
-
(2007)
Pylori VacA Toxin. J. Cell Biol
, vol.177
, pp. 343-354
-
-
Gauthier, N.C.1
Monzo, P.2
Gonzalez, T.3
Doye, A.4
Oldani, A.5
Gounon, P.6
Ricci, V.7
Cormont, M.8
Boquet, P.9
-
72
-
-
0027423455
-
Cell vacuolization induced by Helicobacter pylori: Inhibition by bafilomycins A1, B1, C1 and D
-
Papini, E.; de Bernard, M.; Bugnoli, M.; Milia, E.; Rappuoli, R.; Montecucco, C. Cell vacuolization induced by Helicobacter pylori: Inhibition by bafilomycins A1, B1, C1 and D. FEMS Microbiol. Lett. 1993, 113, 155-159.
-
(1993)
FEMS Microbiol. Lett
, vol.113
, pp. 155-159
-
-
Papini, E.1
de Bernard, M.2
Bugnoli, M.3
Milia, E.4
Rappuoli, R.5
Montecucco, C.6
-
73
-
-
0031032509
-
The small GTP binding protein rab7 is essential for cellular vacuolation induced by Helicobacter pylori cytotoxin
-
Papini, E.; Satin, B.; Bucci, C.; de Bernard, M.; Telford, J.L.; Manetti, R.; Rappuoli, R.; Zerial, M.; Montecucco, C. The small GTP binding protein rab7 is essential for cellular vacuolation induced by Helicobacter pylori cytotoxin. EMBO J. 1997, 16, 15-24.
-
(1997)
EMBO J
, vol.16
, pp. 15-24
-
-
Papini, E.1
Satin, B.2
Bucci, C.3
de Bernard, M.4
Telford, J.L.5
Manetti, R.6
Rappuoli, R.7
Zerial, M.8
Montecucco, C.9
-
74
-
-
0034640406
-
Cell vacuolation induced by the VacA cytotoxin of Helicobacter pylori is regulated by the Rac1 GTPase
-
Hotchin, N.A.; Cover, T.L.; Akhtar, N. Cell vacuolation induced by the VacA cytotoxin of Helicobacter pylori is regulated by the Rac1 GTPase. J. Biol. Chem. 2000, 275, 14009-14012.
-
(2000)
J. Biol. Chem
, vol.275
, pp. 14009-14012
-
-
Hotchin, N.A.1
Cover, T.L.2
Akhtar, N.3
-
75
-
-
0037195810
-
PIKfyve Kinase and SKD1 AAA ATPase define distinct endocytic compartments. Only PIKfyve expression inhibits the cell-vacuolating activity of Helicobacter pylori VacA toxin
-
Ikonomov, O.C.; Sbrissa, D.; Yoshimori, T.; Cover, T.L.; Shisheva, A. PIKfyve Kinase and SKD1 AAA ATPase define distinct endocytic compartments. Only PIKfyve expression inhibits the cell-vacuolating activity of Helicobacter pylori VacA toxin. J. Biol. Chem. 2002, 277, 46785-46790.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 46785-46790
-
-
Ikonomov, O.C.1
Sbrissa, D.2
Yoshimori, T.3
Cover, T.L.4
Shisheva, A.5
-
76
-
-
0036158945
-
Cell vacuolization induced by Helicobacter pylori VacA cytotoxin does not depend on late endosomal SNAREs
-
de Bernard, M.; Moschioni, M.; Habermann, A.; Griffiths, G.; Montecucco, C. Cell vacuolization induced by Helicobacter pylori VacA cytotoxin does not depend on late endosomal SNAREs. Cell. Microbiol. 2002, 4, 11-18.
-
(2002)
Cell. Microbiol
, vol.4
, pp. 11-18
-
-
de Bernard, M.1
Moschioni, M.2
Habermann, A.3
Griffiths, G.4
Montecucco, C.5
-
77
-
-
0037815195
-
Involvement of syntaxin 7 in human gastric epithelial cell vacuolation induced by the Helicobacter pylori-produced cytotoxin VacA
-
Suzuki, J.; Ohnishi, H.; Wada, A.; Hirayama, T.; Ohno, H.; Ueda, N.; Yasuda, H.; Iiri, T.; Wada, Y.; Futai, M.; Mashima, H. Involvement of syntaxin 7 in human gastric epithelial cell vacuolation induced by the Helicobacter pylori-produced cytotoxin VacA. J. Biol. Chem. 2003, 278, 25585-25590.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 25585-25590
-
-
Suzuki, J.1
Ohnishi, H.2
Wada, A.3
Hirayama, T.4
Ohno, H.5
Ueda, N.6
Yasuda, H.7
Iiri, T.8
Wada, Y.9
Futai, M.10
Mashima, H.11
-
78
-
-
0035132561
-
Dynamin is involved in human epithelial cell vacuolation caused by the Helicobacter pylori-produced cytotoxin VacA
-
Suzuki, J.; Ohnsihi, H.; Shibata, H.; Wada, A.; Hirayama, T.; Iiri, T.; Ueda, N.; Kanamaru, C.; Tsuchida, T.; Mashima, H.; Yasuda, H.; Fujita, T. Dynamin is involved in human epithelial cell vacuolation caused by the Helicobacter pylori-produced cytotoxin VacA. J. Clin. Invest. 2001, 107, 363-370.
-
(2001)
J. Clin. Invest
, vol.107
, pp. 363-370
-
-
Suzuki, J.1
Ohnsihi, H.2
Shibata, H.3
Wada, A.4
Hirayama, T.5
Iiri, T.6
Ueda, N.7
Kanamaru, C.8
Tsuchida, T.9
Mashima, H.10
Yasuda, H.11
Fujita, T.12
-
79
-
-
0031741917
-
Identification of the Helicobacter pylori VacA toxin domain active in the cell cytosol
-
de Bernard, M.; Burroni, D.; Papini, E.; Rappuoli, R.; Telford, J.; Montecucco, C. Identification of the Helicobacter pylori VacA toxin domain active in the cell cytosol. Infect. Immun. 1998, 66, 6014-6016.
-
(1998)
Infect. Immun
, vol.66
, pp. 6014-6016
-
-
de Bernard, M.1
Burroni, D.2
Papini, E.3
Rappuoli, R.4
Telford, J.5
Montecucco, C.6
-
80
-
-
0036223741
-
Functional complementation reveals the importance of intermolecular monomer interactions for Helicobacter pylori VacA vacuolating activity
-
Ye, D.; Blanke, S.R. Functional complementation reveals the importance of intermolecular monomer interactions for Helicobacter pylori VacA vacuolating activity. Mol. Microbiol. 2002, 43, 1243-1253.
-
(2002)
Mol. Microbiol
, vol.43
, pp. 1243-1253
-
-
Ye, D.1
Blanke, S.R.2
-
81
-
-
0036081573
-
Fluorescence resonance energy transfer microscopy of the Helicobacter pylori vacuolating cytotoxin within mammalian cells
-
Willhite, D.C.; Ye, D.; Blanke, S.R. Fluorescence resonance energy transfer microscopy of the Helicobacter pylori vacuolating cytotoxin within mammalian cells. Infect. Immun. 2002, 70, 3824-3832.
-
(2002)
Infect. Immun
, vol.70
, pp. 3824-3832
-
-
Willhite, D.C.1
Ye, D.2
Blanke, S.R.3
-
82
-
-
1942501695
-
Membrane channel structure of Helicobacter pylori vacuolating toxin: Role of multiple GXXXG motifs in cylindrical channels
-
Kim, S.; Chamberlain, A.K.; Bowie, J.U. Membrane channel structure of Helicobacter pylori vacuolating toxin: Role of multiple GXXXG motifs in cylindrical channels. Proc. Natl. Acad. Sci. USA 2004, 101, 5988-5991.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 5988-5991
-
-
Kim, S.1
Chamberlain, A.K.2
Bowie, J.U.3
-
83
-
-
13044317274
-
Formation of anion-selective channels in the cell plasma membrane by the toxin VacA of Helicobacter pylori is required for its biological activity
-
Szabó, I.; Brutsche, S.; Tombola, F.; Moschioni, M.; Satin, B.; Telford, J.L.; Rappuoli, R.; Montecucco, C.; Papini, E.; Zoratti, M. Formation of anion-selective channels in the cell plasma membrane by the toxin VacA of Helicobacter pylori is required for its biological activity. EMBO J. 1999, 18, 5517-5527.
-
(1999)
EMBO J
, vol.18
, pp. 5517-5527
-
-
Szabó, I.1
Brutsche, S.2
Tombola, F.3
Moschioni, M.4
Satin, B.5
Telford, J.L.6
Rappuoli, R.7
Montecucco, C.8
Papini, E.9
Zoratti, M.10
-
84
-
-
0006534562
-
Vacuolating cytotoxin purified from Helicobacter pylori causes mitochondrial damage in human gastric cells
-
Kimura, M.; Goto, S.; Wada, A.; Yahiro, K.; Niidome, T.; Hatakeyama, T.; Aoyagi, H.; Hirayama, T.; Kondo, T. Vacuolating cytotoxin purified from Helicobacter pylori causes mitochondrial damage in human gastric cells. Microb. Pathog. 1999, 26, 45-52.
-
(1999)
Microb. Pathog
, vol.26
, pp. 45-52
-
-
Kimura, M.1
Goto, S.2
Wada, A.3
Yahiro, K.4
Niidome, T.5
Hatakeyama, T.6
Aoyagi, H.7
Hirayama, T.8
Kondo, T.9
-
85
-
-
0034388020
-
The N-terminal 34 kDa fragment of Helicobacter pylori vacuolating cytotoxin targets mitochondria and induces cytochrome c release
-
Galmiche, A.; Rassow, J.; Doye, A.; Cagnol, S.; Chambard, J.C.; Contamin, S.; de Thillot, V.; Just, I.; Ricci, V.; Solcia, E.; Van Obberghen, E.; Boquet, P. The N-terminal 34 kDa fragment of Helicobacter pylori vacuolating cytotoxin targets mitochondria and induces cytochrome c release. EMBO J. 2000, 19, 6361-6370.
-
(2000)
EMBO J
, vol.19
, pp. 6361-6370
-
-
Galmiche, A.1
Rassow, J.2
Doye, A.3
Cagnol, S.4
Chambard, J.C.5
Contamin, S.6
de Thillot, V.7
Just, I.8
Ricci, V.9
Solcia, E.10
van Obberghen, E.11
Boquet, P.12
-
86
-
-
0034923765
-
Vacuolating cytotoxin of Helicobacter pylori induces apoptosis in the human gastric epithelial cell line AGS
-
Kuck, D.; Kolmerer, B.; Iking-Konert, C.; Krammer, P.H.; Stremmel, W.; Rudi, J. Vacuolating cytotoxin of Helicobacter pylori induces apoptosis in the human gastric epithelial cell line AGS. Infect. Immun. 2001, 69, 5080-5087.
-
(2001)
Infect. Immun
, vol.69
, pp. 5080-5087
-
-
Kuck, D.1
Kolmerer, B.2
Iking-Konert, C.3
Krammer, P.H.4
Stremmel, W.5
Rudi, J.6
-
87
-
-
0037373880
-
Induction of gastric epithelial cell apoptosis by Helicobacter pylori vacuolating cytotoxin
-
Cover, T.L.; Krishna, U.S.; Israel, D.A.; Peek, R.M. Induction of gastric epithelial cell apoptosis by Helicobacter pylori vacuolating cytotoxin. Cancer Res. 2003, 63, 951-957.
-
(2003)
Cancer Res
, vol.63
, pp. 951-957
-
-
Cover, T.L.1
Krishna, U.S.2
Israel, D.A.3
Peek, R.M.4
-
88
-
-
70350230158
-
Relationship between Vac A toxin and ammonia in Helicobacter pylori-induced apoptosis in human gastric epithelial cells
-
Chiozzi, V.; Mazzini, G.; Oldani, A.; Sciullo, A.; Ventura, U.; Romano, M.; Boquet, P.; Ricci, V. Relationship between Vac A toxin and ammonia in Helicobacter pylori-induced apoptosis in human gastric epithelial cells. J. Physiol. Pharmacol. 2009, 60, 23-30.
-
(2009)
J. Physiol. Pharmacol
, vol.60
, pp. 23-30
-
-
Chiozzi, V.1
Mazzini, G.2
Oldani, A.3
Sciullo, A.4
Ventura, U.5
Romano, M.6
Boquet, P.7
Ricci, V.8
-
89
-
-
0032528956
-
Selective increase of the permeability of polarized epithelial cell monolayers by Helicobacter pylori vacuolating toxin
-
Papini, E.; Satin, B.; Norais, N.; de Bernard, M.; Telford, J.L.; Rappuoli, R.; Montecucco, C. Selective increase of the permeability of polarized epithelial cell monolayers by Helicobacter pylori vacuolating toxin. J. Clin. Invest. 1998, 102, 813-820.
-
(1998)
J. Clin. Invest
, vol.102
, pp. 813-820
-
-
Papini, E.1
Satin, B.2
Norais, N.3
de Bernard, M.4
Telford, J.L.5
Rappuoli, R.6
Montecucco, C.7
-
90
-
-
0032842774
-
Helicobacter pylori VacA cytotoxin associated with the bacteria increases epithelial permeability independently of its vacuolating activity
-
Pelicic, V.; Reyrat, J.M.; Sartori, L.; Pagliaccia, C.; Rappuoli, R.; Telford, J.L.; Montecucco, C.; Papini, E. Helicobacter pylori VacA cytotoxin associated with the bacteria increases epithelial permeability independently of its vacuolating activity. Microbiology 1999, 145, 2043-2050.
-
(1999)
Microbiology
, vol.145
, pp. 2043-2050
-
-
Pelicic, V.1
Reyrat, J.M.2
Sartori, L.3
Pagliaccia, C.4
Rappuoli, R.5
Telford, J.L.6
Montecucco, C.7
Papini, E.8
-
91
-
-
0034836586
-
The Helicobacter pylori VacA toxin is a urea permease that promotes urea diffusion across epithelia
-
Tombola, F.; Morbiato, L.; Del Giudice, G.; Rappuoli, R.; Zoratti, M.; Papini, E. The Helicobacter pylori VacA toxin is a urea permease that promotes urea diffusion across epithelia. J. Clin. Invest. 2001, 108, 929-937.
-
(2001)
J. Clin. Invest
, vol.108
, pp. 929-937
-
-
Tombola, F.1
Morbiato, L.2
del Giudice, G.3
Rappuoli, R.4
Zoratti, M.5
Papini, E.6
-
92
-
-
0038780624
-
Disruption of the epithelial apical-junctional complex by Helicobacter pylori CagA
-
Amieva, M.R.; Vogelmann, R.; Covacci, A.; Tompkins, L.S.; Nelson, W.J.; Falkow, S. Disruption of the epithelial apical-junctional complex by Helicobacter pylori CagA. Science 2003, 300, 1430-1434.
-
(2003)
Science
, vol.300
, pp. 1430-1434
-
-
Amieva, M.R.1
Vogelmann, R.2
Covacci, A.3
Tompkins, L.S.4
Nelson, W.J.5
Falkow, S.6
-
93
-
-
0033860667
-
Effect of Helicobacter pylori on polymorphonuclear leukocyte migration across polarized T84 epithelial cell monolayers: Role of vacuolating toxin VacA and cag pathogenicity island
-
Hofman, V.; Ricci, V.; Galmiche, A.; Brest, P.; Auberger, P.; Rossi, B.; Boquet, P.; Hofman, P. Effect of Helicobacter pylori on polymorphonuclear leukocyte migration across polarized T84 epithelial cell monolayers: Role of vacuolating toxin VacA and cag pathogenicity island. Infect. Immun. 2000, 68, 5225-5233.
-
(2000)
Infect. Immun
, vol.68
, pp. 5225-5233
-
-
Hofman, V.1
Ricci, V.2
Galmiche, A.3
Brest, P.4
Auberger, P.5
Rossi, B.6
Boquet, P.7
Hofman, P.8
-
94
-
-
59849102721
-
Helicobacter pylori dysregulation of gastric epithelial tight junctions by ureasemediated myosin II activation
-
Wroblewski, L.E.; Shen, L.; Ogden, S.; Romero-Gallo, J.; Lapierre, L.A.; Israel, D.A.; Turner, J.R.; Peek, R.M. Helicobacter pylori dysregulation of gastric epithelial tight junctions by ureasemediated myosin II activation. Gastroenterology 2009, 136, 236-246.
-
(2009)
Gastroenterology
, vol.136
, pp. 236-246
-
-
Wroblewski, L.E.1
Shen, L.2
Ogden, S.3
Romero-Gallo, J.4
Lapierre, L.A.5
Israel, D.A.6
Turner, J.R.7
Peek, R.M.8
-
95
-
-
48149105975
-
Molecular mechanisms of epithelial-barrier disruption by Helicobacter pylori
-
Wessler, S.; Backert, S. Molecular mechanisms of epithelial-barrier disruption by Helicobacter pylori. Trends Microbiol. 2008, 16, 397-405.
-
(2008)
Trends Microbiol
, vol.16
, pp. 397-405
-
-
Wessler, S.1
Backert, S.2
-
96
-
-
0031974233
-
Selective inhibition of Ii-dependent antigen presentation by Helicobacter pylori toxin VacA
-
Molinari, M.; Salio, M.; Galli, C.; Norais, N.; Rappuoli, R.; Lanzavecchia, A.; Montecucco, C. Selective inhibition of Ii-dependent antigen presentation by Helicobacter pylori toxin VacA. J. Exp. Med. 1998, 187, 135-140.
-
(1998)
J. Exp. Med
, vol.187
, pp. 135-140
-
-
Molinari, M.1
Salio, M.2
Galli, C.3
Norais, N.4
Rappuoli, R.5
Lanzavecchia, A.6
Montecucco, C.7
-
97
-
-
0037237573
-
Helicobacter pylori strains expressing the vacuolating cytotoxin interrupt phagosome maturation in macrophages by recruiting and retaining TACO (coronin 1) protein
-
Zheng, P.Y.; Jones, N.L. Helicobacter pylori strains expressing the vacuolating cytotoxin interrupt phagosome maturation in macrophages by recruiting and retaining TACO (coronin 1) protein. Cell. Microbiol. 2003, 5, 25-40.
-
(2003)
Cell. Microbiol
, vol.5
, pp. 25-40
-
-
Zheng, P.Y.1
Jones, N.L.2
-
98
-
-
68549125345
-
Pylori escape host immunoreaction through inhibiting ILK expression by VacA
-
Yuan, J.; Li, P.; Tao, J.; Shi, X.; Hu, B.; Chen, H.; Guo, X. H. pylori escape host immunoreaction through inhibiting ILK expression by VacA. Cell. Mol. Immunol. 2009, 6, 191-197.
-
(2009)
Cell. Mol. Immunol
, vol.6
, pp. 191-197
-
-
Yuan, J.1
Li, P.2
Tao, J.3
Shi, X.4
Hu, B.5
Chen, H.6
Guo, X.H.7
-
99
-
-
0033770798
-
Helicobacter pylori inhibits phagocytosis by professional phagocytes involving type IV secretion components
-
Ramarao, N.; Gray-Owen, S.D.; Backert, S.; Meyer, T.F. Helicobacter pylori inhibits phagocytosis by professional phagocytes involving type IV secretion components. Mol. Microbiol. 2000, 37, 1389-1404.
-
(2000)
Mol. Microbiol
, vol.37
, pp. 1389-1404
-
-
Ramarao, N.1
Gray-Owen, S.D.2
Backert, S.3
Meyer, T.F.4
-
100
-
-
0345602791
-
Helicobacter pylori-induced homotypic phagosome fusion in human monocytes is independent of the bacterial vacA and cag status
-
Rittig, M.G.; Shaw, B.; Letley, D.P.; Thomas, R.J.; Argent, R.H.; Atherton, J.C. Helicobacter pylori-induced homotypic phagosome fusion in human monocytes is independent of the bacterial vacA and cag status. Cell. Microbiol. 2003, 5, 887-899.
-
(2003)
Cell. Microbiol
, vol.5
, pp. 887-899
-
-
Rittig, M.G.1
Shaw, B.2
Letley, D.P.3
Thomas, R.J.4
Argent, R.H.5
Atherton, J.C.6
-
101
-
-
0042932364
-
Helicobacter pylori vacuolating cytotoxin inhibits T lymphocyte activation
-
Gebert, B.; Fischer, W.; Weiss, E.; Hoffmann, R.; Haas, R. Helicobacter pylori vacuolating cytotoxin inhibits T lymphocyte activation. Science 2003, 301, 1099-1102.
-
(2003)
Science
, vol.301
, pp. 1099-1102
-
-
Gebert, B.1
Fischer, W.2
Weiss, E.3
Hoffmann, R.4
Haas, R.5
-
102
-
-
9144220868
-
The Helicobacter pylori vacuolating toxin inhibits T cell activation by two independent mechanisms
-
Boncristiano, M.; Paccani, S.R.; Barone, S.; Ulivieri, C.; Patrussi, L.; Ilver, D.; Amedei, A.; D'Elios, M.M.; Telford, J.L.; Baldari, C.T. The Helicobacter pylori vacuolating toxin inhibits T cell activation by two independent mechanisms. J. Exp. Med. 2003, 198, 1887-1897.
-
(2003)
J. Exp. Med
, vol.198
, pp. 1887-1897
-
-
Boncristiano, M.1
Paccani, S.R.2
Barone, S.3
Ulivieri, C.4
Patrussi, L.5
Ilver, D.6
Amedei, A.7
D'elios, M.M.8
Telford, J.L.9
Baldari, C.T.10
-
103
-
-
2442682964
-
Inhibition of primary human T cell proliferation by Helicobacter pylori vacuolating toxin (VacA) is independent of VacA effects on IL-2 secretion
-
Sundrud, M.S.; Torres, V.J.; Unutmaz, D.; Cover, T.L. Inhibition of primary human T cell proliferation by Helicobacter pylori vacuolating toxin (VacA) is independent of VacA effects on IL-2 secretion. Proc. Natl. Acad. Sci. USA 2004, 101, 7727-7732.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 7727-7732
-
-
Sundrud, M.S.1
Torres, V.J.2
Unutmaz, D.3
Cover, T.L.4
-
104
-
-
10744222029
-
Helicobacter pylori VacA activates the p38/activating transcription factor 2-mediated signal pathway in AZ-521 cells
-
Nakayama, M.; Kimura, M.; Wada, A.; Yahiro, K.; Ogushi, K.; Niidome, T.; Fujikawa, A.; Shirasaka, D.; Aoyama, N.; Kurazono, H.; Noda, M.; Moss, J.; Hirayama, T. Helicobacter pylori VacA activates the p38/activating transcription factor 2-mediated signal pathway in AZ-521 cells. J. Biol. Chem. 2004, 279, 7024-7028.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 7024-7028
-
-
Nakayama, M.1
Kimura, M.2
Wada, A.3
Yahiro, K.4
Ogushi, K.5
Niidome, T.6
Fujikawa, A.7
Shirasaka, D.8
Aoyama, N.9
Kurazono, H.10
Noda, M.11
Moss, J.12
Hirayama, T.13
-
105
-
-
44449153085
-
Molecular characterization of Helicobacter pylori VacA induction of IL-8 in U937 cells reveals a prominent role for p38MAPK in activating transcription factor-2, cAMP response element binding protein, and NF-kappaB activation
-
Hisatsune, J.; Nakayama, M.; Isomoto, H.; Kurazono, H.; Mukaida, N.; Mukhopadhyay, A.K.; Azuma, T.; Yamaoka, Y.; Sap, J.; Yamasaki, E.; Yahiro, K.; Moss, J.; Hirayama, T. Molecular characterization of Helicobacter pylori VacA induction of IL-8 in U937 cells reveals a prominent role for p38MAPK in activating transcription factor-2, cAMP response element binding protein, and NF-kappaB activation. J. Immunol. 2008, 180, 5017-5027.
-
(2008)
J. Immunol
, vol.180
, pp. 5017-5027
-
-
Hisatsune, J.1
Nakayama, M.2
Isomoto, H.3
Kurazono, H.4
Mukaida, N.5
Mukhopadhyay, A.K.6
Azuma, T.7
Yamaoka, Y.8
Sap, J.9
Yamasaki, E.10
Yahiro, K.11
Moss, J.12
Hirayama, T.13
-
106
-
-
68349084684
-
Helicobacter pylori VacA activates NF-kappaB in T cells via the classical but not alternative pathway
-
Takeshima, E.; Tomimori, K.; Takamatsu, R.; Ishikawa, C.; Kinjo, F.; Hirayama, T.; Fujita, J.; Mori, N. Helicobacter pylori VacA activates NF-kappaB in T cells via the classical but not alternative pathway. Helicobacter 2009, 14, 271-279.
-
(2009)
Helicobacter
, vol.14
, pp. 271-279
-
-
Takeshima, E.1
Tomimori, K.2
Takamatsu, R.3
Ishikawa, C.4
Kinjo, F.5
Hirayama, T.6
Fujita, J.7
Mori, N.8
-
107
-
-
13844315698
-
The Helicobacter pylori VacA cytotoxin activates RBL-2H3 cells by inducing cytosolic calcium oscillations
-
de Bernard, M.; Cappon, A.; Pancotto, L.; Ruggiero, P.; Rivera, J.; Del Giudice, G.; ontecucco, C. The Helicobacter pylori VacA cytotoxin activates RBL-2H3 cells by inducing cytosolic calcium oscillations. Cell. Microbiol. 2005, 7, 191-198.
-
(2005)
Cell. Microbiol
, vol.7
, pp. 191-198
-
-
de Bernard, M.1
Cappon, A.2
Pancotto, L.3
Ruggiero, P.4
Rivera, J.5
del Giudice, G.6
Montecucco, C.7
-
108
-
-
0037087302
-
Cutting edge: VacA, a vacuolating cytotoxin of Helicobacter pylori, directly activates mast cells for migration and production of proinflammatory cytokines
-
Supajatura, V.; Ushio, H.; Wada, A.; Yahiro, K.; Okumura, K.; Ogawa, H.; Hirayama, T.; Ra, C. Cutting edge: VacA, a vacuolating cytotoxin of Helicobacter pylori, directly activates mast cells for migration and production of proinflammatory cytokines. J. Immunol. 2002, 168, 2603-2607.
-
(2002)
J. Immunol
, vol.168
, pp. 2603-2607
-
-
Supajatura, V.1
Ushio, H.2
Wada, A.3
Yahiro, K.4
Okumura, K.5
Ogawa, H.6
Hirayama, T.7
Ra, C.8
-
109
-
-
73349087208
-
Helicobacter pylori counteracts the apoptotic action of its VacA toxin by injecting the CagA protein into gastric epithelial cells
-
doi:10.1371/journal.ppat.1000603
-
Oldani, A.; Cormont, M.; Hofman, V.; Chiozzi, V.; Oregioni, O; Canonici, A; Sciullo, A; Sommi, P.; Fabbri, A.; Ricci, V.; Boquet P. Helicobacter pylori counteracts the apoptotic action of its VacA toxin by injecting the CagA protein into gastric epithelial cells. PLoS Pathog. 2009, 5, doi:10.1371/journal.ppat.1000603.
-
(2009)
PLoS Pathog
, vol.5
-
-
Oldani, A.1
Cormont, M.2
Hofman, V.3
Chiozzi, V.4
Oregioni, O.5
Canonici, A.6
Sciullo, A.7
Sommi, P.8
Fabbri, A.9
Ricci, V.10
Boquet, P.11
-
110
-
-
22144474386
-
Functional antagonism between Helicobacter pylori CagA and vacuolating toxin VacA in control of the NFAT signalling pathway in gastric epithelial cells
-
Yokoyama, K.; Higashi, H.; Ishikawa, S.; Fujii, Y.; Kondo, S.; Kato, H.; Azuma, T.; Wada, A.; Hirayama, T.; Aburatani, H.; Hatakeyama, M. Functional antagonism between Helicobacter pylori CagA and vacuolating toxin VacA in control of the NFAT signalling pathway in gastric epithelial cells. Proc. Natl. Acad. Sci. USA 2005, 102, 9661-9666.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 9661-9666
-
-
Yokoyama, K.1
Higashi, H.2
Ishikawa, S.3
Fujii, Y.4
Kondo, S.5
Kato, H.6
Azuma, T.7
Wada, A.8
Hirayama, T.9
Aburatani, H.10
Hatakeyama, M.11
-
111
-
-
38949164779
-
Functional association between the Helicobacter pylori virulence factors VacA and CagA
-
Argent, R.H.; Thomas, R.J.; Letley, D.P.; Rittig, M.G.; Hardie, K.R.; Atherton, J.C. Functional association between the Helicobacter pylori virulence factors VacA and CagA. J Med. Microbiol. 2008, 57, 145-150.
-
(2008)
J Med. Microbiol
, vol.57
, pp. 145-150
-
-
Argent, R.H.1
Thomas, R.J.2
Letley, D.P.3
Rittig, M.G.4
Hardie, K.R.5
Atherton, J.C.6
-
112
-
-
59849112591
-
Importance of EGF receptor, HER2/Neu and Erk1/2 kinase signalling for host cell elongation and scattering induced by the Helicobacter pylori CagA protein: Antagonistic effects of the vacuolating cytotoxin VacA
-
Tegtmeyer, N.; Zabler, D.; Schmidt, D.; Hartig, R.; Brandt, S.; Backert, S. Importance of EGF receptor, HER2/Neu and Erk1/2 kinase signalling for host cell elongation and scattering induced by the Helicobacter pylori CagA protein: Antagonistic effects of the vacuolating cytotoxin VacA. Cell. Microbiol. 2009, 11, 488-505.
-
(2009)
Cell. Microbiol
, vol.11
, pp. 488-505
-
-
Tegtmeyer, N.1
Zabler, D.2
Schmidt, D.3
Hartig, R.4
Brandt, S.5
Backert, S.6
-
113
-
-
8944232864
-
Effect of Helicobacter pylori on gastric epithelial cell migration and proliferation in vitro: Role of VacA and CagA
-
Ricci, V.; Ciacci, C.; Zarrilli, R.; Sommi, P.; Tummuru, M.K.; Del Vecchio Blanco, C.; Bruni, C.B.; Cover, T.L.; Blaser, M.J.; Romano, M. Effect of Helicobacter pylori on gastric epithelial cell migration and proliferation in vitro: Role of VacA and CagA. Infect. Immun. 1996, 64, 2829-2833.
-
(1996)
Infect. Immun
, vol.64
, pp. 2829-2833
-
-
Ricci, V.1
Ciacci, C.2
Zarrilli, R.3
Sommi, P.4
Tummuru, M.K.5
del Vecchio, B.C.6
Bruni, C.B.7
Cover, T.L.8
Blaser, M.J.9
Romano, M.10
-
114
-
-
0031778021
-
Helicobacter pylori culture supernatant interferes with epidermal growth factor-activated signal transduction in human gastric KATO III cells
-
Pai, R.; Wyle, F.A.; Cover, T.L.; Itani, R.M.; Domek, M.J.; Tarnawski, A.S. Helicobacter pylori culture supernatant interferes with epidermal growth factor-activated signal transduction in human gastric KATO III cells. Am. J. Pathol. 1998, 152, 1617-1624.
-
(1998)
Am. J. Pathol
, vol.152
, pp. 1617-1624
-
-
Pai, R.1
Wyle, F.A.2
Cover, T.L.3
Itani, R.M.4
Domek, M.J.5
Tarnawski, A.S.6
-
115
-
-
0033747967
-
Helicobacter pylori vacuolating cytotoxin (VacA) alters cytoskeleton-associated proteins and interferes with re-epithelialization of wounded gastric epithelial monolayers
-
Pai, R.; Sasaki, E.; Tarnawski, A.S. Helicobacter pylori vacuolating cytotoxin (VacA) alters cytoskeleton-associated proteins and interferes with re-epithelialization of wounded gastric epithelial monolayers. Cell Biol. Int. 2000, 24, 291-301.
-
(2000)
Cell Biol. Int
, vol.24
, pp. 291-301
-
-
Pai, R.1
Sasaki, E.2
Tarnawski, A.S.3
-
116
-
-
0347132270
-
Helicobacter pylori infection inhibits healing of the wounded duodenal epithelium in vitro
-
Tabel, G.; Hoa, N.T.; Tarnawski, A.; Chen, J.; Domek, M; Ma, T.Y. Helicobacter pylori infection inhibits healing of the wounded duodenal epithelium in vitro. J. Lab. Clin. Med. 2003, 142, 421-430.
-
(2003)
J. Lab. Clin. Med
, vol.142
, pp. 421-430
-
-
Tabel, G.1
Hoa, N.T.2
Tarnawski, A.3
Chen, J.4
Domek, M.5
Ma, T.Y.6
-
117
-
-
0030764202
-
Effect of Helicobacter pylori vacuolating toxin on maturation and extracellular release of procathepsin D and on epidermal growth factor degradation
-
Satin, B.; Norais, N.; Telford, J.; Rappuoli, R.; Murgia, M.; Montecucco, C.; Papini, E. Effect of Helicobacter pylori vacuolating toxin on maturation and extracellular release of procathepsin D and on epidermal growth factor degradation. J. Biol. Chem. 1997, 272, 25022-25028.
-
(1997)
J. Biol. Chem
, vol.272
, pp. 25022-25028
-
-
Satin, B.1
Norais, N.2
Telford, J.3
Rappuoli, R.4
Murgia, M.5
Montecucco, C.6
Papini, E.7
-
118
-
-
59449108480
-
Helicobacter pylori VacA-induced inhibition of GSK3 through the PI3K/Akt signalling pathway
-
Nakayama, M.; Hisatsune, J.; Yamasaki, E.; Isomoto, H.; Kurazono, H.; Hatakeyama, M.; Azuma, T.; Yamaoka, Y.; Yahiro, K.; Moss, J.; Hirayama, T. Helicobacter pylori VacA-induced inhibition of GSK3 through the PI3K/Akt signalling pathway. J. Biol. Chem. 2009, 284, 1612-1619.
-
(2009)
J. Biol. Chem
, vol.284
, pp. 1612-1619
-
-
Nakayama, M.1
Hisatsune, J.2
Yamasaki, E.3
Isomoto, H.4
Kurazono, H.5
Hatakeyama, M.6
Azuma, T.7
Yamaoka, Y.8
Yahiro, K.9
Moss, J.10
Hirayama, T.11
|