Activation of Helicobacter pylori VacA toxin by alkaline or acid conditions increases its binding to a 250-kDa receptor protein-tyrosine phosphatase β

Journal of Biological Chemistry

Volumn 274, Issue 51, 1999, Pages 36693-36699

  Yahiro, Kinnosuke ^a   Niidome, Takuro ^a   Kimura, Miyuki ^a   Hatakeyama, Tomomitsu ^a   Aoyagi, Haruhiko ^a   Kurazono, Hisao ^b   Imagawa, Ken Ichi ^c   Wada, Akihiro ^a   Moss, Joel ^d   Hirayama, Toshiya ^a  

^a NAGASAKI UNIVERSITY   (Japan)

^b UNIVERSITY OF TSUKUBA   (Japan)

^c OTSUKA PHARMACEUTICAL CO LTD   (Japan)

^d NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL TOXIN; CYTOTOXIN; GALACTOSE; MEMBRANE PROTEIN; N ACETYLGLUCOSAMINE; POLYCLONAL ANTIBODY; PROTEIN TYROSINE PHOSPHATASE;

ACIDIFICATION; ALKALINIZATION; ARTICLE; CELL VACUOLE; ENZYME BINDING; FLOW CYTOMETRY; HELICOBACTER PYLORI; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; IMMUNOPRECIPITATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN ASSEMBLY;

AMINO ACID SEQUENCE; BACTERIAL PROTEINS; BACTERIAL TOXINS; BINDING SITES; HELICOBACTER PYLORI; HUMANS; HYDROGEN-ION CONCENTRATION; MOLECULAR SEQUENCE DATA; NERVE TISSUE PROTEINS; PROTEIN BINDING; PROTEIN-TYROSINE-PHOSPHATASE;

ARACHIS HYPOGAEA; BACTERIA (MICROORGANISMS); HELICOBACTER PYLORI; NEGIBACTERIA;

EID: 0033579575     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.51.36693     Document Type: Article

References (31)

1. NIH Consensus Development Panel on Helicobacter pylori in Peptic Ulcer Disease (1994) J. Am. Med. Assoc. 272, 65-69
2. Ghiara, P., Marchetti, M., Blaser, M. J., Tummuru, M. K. R., Cover, T. L., Segal, E. D., Tompkins, L. S., and Rappuoli, R. (1995) Infect. Immun. 63, 4154-4160
3. Telford, J. L., Ghiara, P., Dell'Orco, M., Comanducci, M., Burroni, D., Bugnoli, M., Tecce, M. F., Censini, S., Covacci, A., Xiang, Z. Y., Papini, E., Montecucco, C., Parente, L., and Rappuoli, R. (1994) J. Exp. Med. 179, 1653-1658
4. Atherton, J. C., Cao, P., Peek, R. M., Jr., Tummuru, M. K. R., Blaser, M. J., and Cover, T. L. (1995) J. Biol Chem. 270, 17771-17777
5. Cover, T. L., Tummuru, M. K., Cao, P., Thompson, S. A., and Blaser, M. J. (1994) J. Biol. Chem. 269, 10566-10573
6. Cover, T. L., and Blaser, M. J. (1992) J. Biol. Chem. 267, 10570-10575
7. Manetti, R., Massari, P., Burroni, D., de Bernard, M., Marchini, A., Olivieri, R., Papini, E., Montecucco, C., Rappuoli, R., and Telford, J. L. (1995) Infect. Immun. 63, 4476-4480
8. de Bernard, M., Papini, E., de Filippis, V., Gottardi, E., Telford, J., Manetti, R., Fontana, A., Rappuoli, R., and Montecucco, C. (1995) J. Biol. Chem. 270, 23937-23940
9. Eaton, K. A., Brooks, C. L., Morgan, D. R., and Krakowka, S. (1991) Infect. Immun. 59, 2470-2475
10. Chen, X. G., Correa, P., Offerhaus, J., Rodriguez, E., Janney, F., Hoffmann, E., Fox, J., Hunter, J., and Diavolitsis, S. (1983) Am J. Clin. Pathol. 86, 575-582
11. Caselli, M., Figura, N., Trevisani, L., Pazzi, P., Guglielmetti, P., Bovolenta, M. R., and Stabellini, G. (1989) Am. J. Gastroenterol. 84, 511-513
12. Hessey, S. J., Spencer, J., Wyatt, J. I., Sobala, G., Rathbone, B. J., Axon, A. T. R., and Dixon, M. F. (1990) Gut 31, 134-138
13. Smoot, D. T., Resau, J. H., Naab, T., Desbordes, B. C., Gilliam, T., Bull-Henry, K., Curry, S. B., Nidiry, J., Sewchand, J., Mills-Robertson, K., Frontin, K., Abebe, E., Dillon, M., Chippendale, G. R., Phelps, P. C., Scott, V. F., and Mobley, H. L. T. (1993) Infect. Immun. 61, 350-355
14. Frieri, G., de Petris, G., Aggio, A., Santarelli, D., Ligas, E., Rosoni, R., and Caprill, R. (1995) Digestion 56, 107-110
15. Yahiro, K., Niidome, T., Hatakeyama, T., Aoyagi, H., Kurazono, H., Padilla, P. I., Wada, A., and Hirayama, T. (1997) Biochem. Biophys. Res. Commun. 238, 629-632
16. Cover, T. L., Puryear, W., Perez-Perez, G. I., and Blaser, M. J. (1991) Infect. Immun. 59, 1264-1270
17. Laemmli, U. K. (1970) Nature 227, 680-685
18. Shibuya, N., Goldstein, I. J., Van Damme, E. J. M., and Peumans, W. J. (1988) J. Biol. Chem. 263, 728-734
19. Shibuya, N., Goldstein, I. J., Broekaert, W. F., Nsimaba-Lubaki, M., Peeters, B., and Peumans, W. J. (1987) J. Biol. Chem. 262, 1596-1601
20. Wang, W.-C., and Cummings, R. D. (1986) J. Biol. Chem. 263, 4576-4585
21. Neurohr, K. J., Young, N. M., and Mantsch, H. H. (1980) J. Biol. Chem. 255, 9205-9209
22. Crowley, J. F., Goldstein, I. J., Arnarp, J., and Lönngren, J. (1984) Arch. Biochem. Biophys. 231, 524-533
23. Iwamatsu, A., and Yoshida-Kubomura, N. (1996) J. Biochem. (Tokyo) 120, 29-34
24. Bradford, M. M. (1976) Anal. Biochem. 72, 248-254
25. Cover, T. L., Hanson, P. I., and Heuser, J. E. (1997) J. Cell Biol. 138, 759-769
26. Krueger, N. X., and Saito, H. (1992) Proc. Natl. Acad. Sci. U.S.A. 89, 7417-7421
27. Levy, J. B., Canoll, P. D., Silvennoinen, O., Barnea, G., Morse, B., Honegger, A. M., Huang, J. T., Cannizzaro, L. A., Park, S. H., Druck, T., Huebner, K., Sap, J., Ehrlich, M., Musacchio, J. M., and Schlessinger, J. (1993) J. Biol. Chem. 268, 10573-10581
28. Czajkowsky, D. M., Iwamoto, H., Cover, T. L., and Shao, Z. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 2001-2006
29. Massari, P., Manetti, R., Burroni, D., Nuti, S., Norais, N., Rappuoli, R., and Telford, J. L. (1998) Infect. Immun. 66, 3981-3984
30. Nishiwaki, T., Maeda, N., and Noda, M. (1998) J. Biochem. (Tokyo) 123, 458-467
31. Pai R, Wyle, F. A., Cover, T. L., Itani, R. M., Domek, M. J., and Tarnawski, A. S. (1998) Am. J. Pathol. 152, 1617-1624