-
1
-
-
0036307727
-
Multiple oligomeric states of the Helicobacter pylori vacuolating toxin demonstrated by cryo-electron microscopy
-
M. Adrian, T.L. Cover, J. Dubochet, and J.E. Heuser Multiple oligomeric states of the Helicobacter pylori vacuolating toxin demonstrated by cryo-electron microscopy J. Mol. Biol. 318 2002 121 133
-
(2002)
J. Mol. Biol.
, vol.318
, pp. 121-133
-
-
Adrian, M.1
Cover, T.L.2
Dubochet, J.3
Heuser, J.E.4
-
4
-
-
85047691456
-
Helicobacter pylori persistence: Biology and disease
-
M.J. Blaser, and J.C. Atherton Helicobacter pylori persistence: biology and disease J. Clin. Invest. 113 2004 321 333
-
(2004)
J. Clin. Invest.
, vol.113
, pp. 321-333
-
-
Blaser, M.J.1
Atherton, J.C.2
-
5
-
-
9144220868
-
The Helicobacter pylori vacuolating toxin inhibits T cell activation by two independent mechanisms
-
M. Boncristiano, S.R. Paccani, S. Barone, C. Ulivieri, L. Patrussi, D. Ilver, A. Amedei, M.M. D'Elios, J.L. Telford, and C.T. Baldari The Helicobacter pylori vacuolating toxin inhibits T cell activation by two independent mechanisms J. Exp. Med. 198 2003 1887 1897
-
(2003)
J. Exp. Med.
, vol.198
, pp. 1887-1897
-
-
Boncristiano, M.1
Paccani, S.R.2
Barone, S.3
Ulivieri, C.4
Patrussi, L.5
Ilver, D.6
Amedei, A.7
D'Elios, M.M.8
Telford, J.L.9
Baldari, C.T.10
-
7
-
-
15944418287
-
Helicobacter pylori VacA, a paradigm for toxin multifunctionality
-
T.L. Cover, and S.R. Blanke Helicobacter pylori VacA, a paradigm for toxin multifunctionality Nat. Rev. Microbiol. 3 2005 320 332
-
(2005)
Nat. Rev. Microbiol.
, vol.3
, pp. 320-332
-
-
Cover, T.L.1
Blanke, S.R.2
-
8
-
-
0026739795
-
Purification and characterization of the vacuolating toxin from Helicobacter pylori
-
T.L. Cover, and M.J. Blaser Purification and characterization of the vacuolating toxin from Helicobacter pylori J. Biol. Chem. 267 1992 10570 10575
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 10570-10575
-
-
Cover, T.L.1
Blaser, M.J.2
-
9
-
-
0030809535
-
Acid-induced dissociation of VacA, the Helicobacter pylori vacuolating cytotoxin, reveals its pattern of assembly
-
T.L. Cover, P.I. Hanson, and J.E. Heuser Acid-induced dissociation of VacA, the Helicobacter pylori vacuolating cytotoxin, reveals its pattern of assembly J. Cell Biol. 138 1997 759 769
-
(1997)
J. Cell Biol.
, vol.138
, pp. 759-769
-
-
Cover, T.L.1
Hanson, P.I.2
Heuser, J.E.3
-
10
-
-
0033515072
-
The vacuolating toxin from Helicobacter pylori forms hexameric pores in lipid bilayers at low pH
-
D.M. Czajkowsky, H. Iwamoto, T.L. Cover, and Z. Shao The vacuolating toxin from Helicobacter pylori forms hexameric pores in lipid bilayers at low pH Proc. Natl. Acad. Sci. USA 96 1999 2001 2006
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 2001-2006
-
-
Czajkowsky, D.M.1
Iwamoto, H.2
Cover, T.L.3
Shao, Z.4
-
11
-
-
2442696577
-
The multiple cellular activities of the VacA cytotoxin of Helicobacter pylori
-
M. de Bernard, A. Cappon, G. Del Giudice, R. Rappuoli, and C. Montecucco The multiple cellular activities of the VacA cytotoxin of Helicobacter pylori Int. J. Med. Microbiol. 293 2004 589 597
-
(2004)
Int. J. Med. Microbiol.
, vol.293
, pp. 589-597
-
-
De Bernard, M.1
Cappon, A.2
Del Giudice, G.3
Rappuoli, R.4
Montecucco, C.5
-
12
-
-
0036427905
-
Cryo-negative staining reduces electron-beam sensitivity of vitrified biological particles
-
S. De Carlo, C. El-Bez, C. Alvarez-Rua, J. Borge, and J. Dubochet Cryo-negative staining reduces electron-beam sensitivity of vitrified biological particles J. Struct. Biol. 138 2002 216 226
-
(2002)
J. Struct. Biol.
, vol.138
, pp. 216-226
-
-
De Carlo, S.1
El-Bez, C.2
Alvarez-Rua, C.3
Borge, J.4
Dubochet, J.5
-
13
-
-
0027418576
-
The portal protein of bacteriophage SPP1: A DNA pump with 13-fold symmetry
-
P. Dube, P. Tavares, R. Lurz, and M. van Heel The portal protein of bacteriophage SPP1: a DNA pump with 13-fold symmetry EMBO J. 12 1993 1303 1309
-
(1993)
EMBO J.
, vol.12
, pp. 1303-1309
-
-
Dube, P.1
Tavares, P.2
Lurz, R.3
Van Heel, M.4
-
14
-
-
0029975088
-
SPIDER and WEB: Processing and visualization of images in 3D electron microscopy and related fields
-
J. Frank, M. Radermacher, P. Penczek, J. Zhu, Y. Li, M. Ladjadj, and A. Leith SPIDER and WEB: processing and visualization of images in 3D electron microscopy and related fields J. Struct. Biol. 116 1996 190 199
-
(1996)
J. Struct. Biol.
, vol.116
, pp. 190-199
-
-
Frank, J.1
Radermacher, M.2
Penczek, P.3
Zhu, J.4
Li, Y.5
Ladjadj, M.6
Leith, A.7
-
15
-
-
0037370481
-
Mice deficient in protein tyrosine phosphatase receptor type Z are resistant to gastric ulcer induction by VacA of Helicobacter pylori
-
A. Fujikawa, D. Shirasaka, S. Yamamoto, H. Ota, K. Yahiro, M. Fukada, T. Shintani, A. Wada, N. Aoyama, T. Hirayama, H. Fukamachi, and M. Noda Mice deficient in protein tyrosine phosphatase receptor type Z are resistant to gastric ulcer induction by VacA of Helicobacter pylori Nat. Genet. 33 2003 375 381
-
(2003)
Nat. Genet.
, vol.33
, pp. 375-381
-
-
Fujikawa, A.1
Shirasaka, D.2
Yamamoto, S.3
Ota, H.4
Yahiro, K.5
Fukada, M.6
Shintani, T.7
Wada, A.8
Aoyama, N.9
Hirayama, T.10
Fukamachi, H.11
Noda, M.12
-
16
-
-
0034388020
-
The N-terminal 34 kDa fragment of Helicobacter pylori vacuolating cytotoxin targets mitochondria and induces cytochrome c release
-
A. Galmiche, J. Rassow, A. Doye, S. Cagnol, J.C. Chambard, S. Contamin, V. de Thillot, I. Just, V. Ricci, E. Solcia, E. Van Obberghen, and P. Boquet The N-terminal 34 kDa fragment of Helicobacter pylori vacuolating cytotoxin targets mitochondria and induces cytochrome c release EMBO J. 19 2000 6361 6370
-
(2000)
EMBO J.
, vol.19
, pp. 6361-6370
-
-
Galmiche, A.1
Rassow, J.2
Doye, A.3
Cagnol, S.4
Chambard, J.C.5
Contamin, S.6
De Thillot, V.7
Just, I.8
Ricci, V.9
Solcia, E.10
Van Obberghen, E.11
Boquet, P.12
-
17
-
-
9444223670
-
The Helicobacter pylori vacuolating cytotoxin: From cellular vacuolation to immunosuppressive activities
-
B. Gebert, W. Fischer, and R. Haas The Helicobacter pylori vacuolating cytotoxin: from cellular vacuolation to immunosuppressive activities Rev. Physiol. Biochem. Pharmacol. 152 2004 205 220
-
(2004)
Rev. Physiol. Biochem. Pharmacol.
, vol.152
, pp. 205-220
-
-
Gebert, B.1
Fischer, W.2
Haas, R.3
-
18
-
-
0042932364
-
Helicobacter pylori vacuolating cytotoxin inhibits T lymphocyte activation
-
B. Gebert, W. Fischer, E. Weiss, R. Hoffmann, and R. Haas Helicobacter pylori vacuolating cytotoxin inhibits T lymphocyte activation Science 301 2003 1099 1102
-
(2003)
Science
, vol.301
, pp. 1099-1102
-
-
Gebert, B.1
Fischer, W.2
Weiss, E.3
Hoffmann, R.4
Haas, R.5
-
19
-
-
0033007098
-
VacA from Helicobacter pylori: A hexameric chloride channel
-
H. Iwamoto, D.M. Czajkowsky, T.L. Cover, G. Szabo, and Z. Shao VacA from Helicobacter pylori: a hexameric chloride channel FEBS Lett. 450 1999 101 104
-
(1999)
FEBS Lett.
, vol.450
, pp. 101-104
-
-
Iwamoto, H.1
Czajkowsky, D.M.2
Cover, T.L.3
Szabo, G.4
Shao, Z.5
-
20
-
-
0037076540
-
GXXXG and AXXXA: Common alpha-helical interaction motifs in proteins, particularly in extremophiles
-
G. Kleiger, R. Grothe, P. Mallick, and D. Eisenberg GXXXG and AXXXA: common alpha-helical interaction motifs in proteins, particularly in extremophiles Biochemistry 41 2002 5990 5997
-
(2002)
Biochemistry
, vol.41
, pp. 5990-5997
-
-
Kleiger, G.1
Grothe, R.2
Mallick, P.3
Eisenberg, D.4
-
21
-
-
0034923765
-
Vacuolating cytotoxin of Helicobacter pylori induces apoptosis in the human gastric epithelial cell line AGS
-
D. Kuck, B. Kolmerer, C. Iking-Konert, P.H. Krammer, W. Stremmel, and J. Rudi Vacuolating cytotoxin of Helicobacter pylori induces apoptosis in the human gastric epithelial cell line AGS Infect. Immun. 69 2001 5080 5087
-
(2001)
Infect. Immun.
, vol.69
, pp. 5080-5087
-
-
Kuck, D.1
Kolmerer, B.2
Iking-Konert, C.3
Krammer, P.H.4
Stremmel, W.5
Rudi, J.6
-
22
-
-
0031928120
-
Three-dimensional reconstruction of metal replicas of the Helicobacter pylori vacuolating cytotoxin
-
S. Lanzavecchia, P.L. Bellon, P. Lupetti, R. Dallai, R. Rappuoli, and J.L. Telford Three-dimensional reconstruction of metal replicas of the Helicobacter pylori vacuolating cytotoxin J. Struct. Biol. 121 1998 9 18
-
(1998)
J. Struct. Biol.
, vol.121
, pp. 9-18
-
-
Lanzavecchia, S.1
Bellon, P.L.2
Lupetti, P.3
Dallai, R.4
Rappuoli, R.5
Telford, J.L.6
-
23
-
-
0023912268
-
Cytotoxic activity in broth-culture filtrates of Campylobacter pylori. J
-
R.D. Leunk, P.T. Johnson, B.C. David, W.G. Kraft, and D.R. Morgan Cytotoxic activity in broth-culture filtrates of Campylobacter pylori. J Med. Microbiol. 26 1988 93 99
-
(1988)
Med. Microbiol.
, vol.26
, pp. 93-99
-
-
Leunk, R.D.1
Johnson, P.T.2
David, B.C.3
Kraft, W.G.4
Morgan, D.R.5
-
24
-
-
1642464598
-
Clustering and redistribution of late endocytic compartments in response to Helicobacter pylori vacuolating toxin
-
Y. Li, A. Wandinger-Ness, J.R. Goldenring, and T.L. Cover Clustering and redistribution of late endocytic compartments in response to Helicobacter pylori vacuolating toxin Mol. Biol. Cell. 15 2004 1946 1959
-
(2004)
Mol. Biol. Cell.
, vol.15
, pp. 1946-1959
-
-
Li, Y.1
Wandinger-Ness, A.2
Goldenring, J.R.3
Cover, T.L.4
-
25
-
-
0029898566
-
Oligomeric and subunit structure of the Helicobacter pylori vacuolating cytotoxin
-
P. Lupetti, J.E. Heuser, R. Manetti, P. Massari, S. Lanzavecchia, P.L. Bellon, R. Dallai, R. Rappuoli, and J.L. Telford Oligomeric and subunit structure of the Helicobacter pylori vacuolating cytotoxin J. Cell Biol. 133 1996 801 807
-
(1996)
J. Cell Biol.
, vol.133
, pp. 801-807
-
-
Lupetti, P.1
Heuser, J.E.2
Manetti, R.3
Massari, P.4
Lanzavecchia, S.5
Bellon, P.L.6
Dallai, R.7
Rappuoli, R.8
Telford, J.L.9
-
26
-
-
0035145404
-
Amino-terminal hydrophobic region of Helicobacter pylori vacuolating cytotoxin (VacA) mediates transmembrane protein dimerization
-
M.S. McClain, P. Cao, and T.L. Cover Amino-terminal hydrophobic region of Helicobacter pylori vacuolating cytotoxin (VacA) mediates transmembrane protein dimerization Infect. Immun. 69 2001 1181 1184
-
(2001)
Infect. Immun.
, vol.69
, pp. 1181-1184
-
-
McClain, M.S.1
Cao, P.2
Cover, T.L.3
-
27
-
-
0034750730
-
A 12-amino-acid segment, present in type s2 but not type s1 Helicobacter pylori VacA proteins, abolishes cytotoxin activity and alters membrane channel formation
-
M.S. McClain, P. Cao, H. Iwamoto, A.D. Vinion-Dubiel, G. Szabo, Z. Shao, and T.L. Cover A 12-amino-acid segment, present in type s2 but not type s1 Helicobacter pylori VacA proteins, abolishes cytotoxin activity and alters membrane channel formation J. Bacteriol. 183 2001 6499 6508
-
(2001)
J. Bacteriol.
, vol.183
, pp. 6499-6508
-
-
McClain, M.S.1
Cao, P.2
Iwamoto, H.3
Vinion-Dubiel, A.D.4
Szabo, G.5
Shao, Z.6
Cover, T.L.7
-
28
-
-
0037561932
-
Essential role of a GXXXG motif for membrane channel formation by Helicobacter pylori vacuolating toxin
-
M.S. McClain, H. Iwamoto, P. Cao, A.D. Vinion-Dubiel, Y. Li, G. Szabo, Z. Shao, and T.L. Cover Essential role of a GXXXG motif for membrane channel formation by Helicobacter pylori vacuolating toxin J. Biol. Chem. 278 2003 12101 12108
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 12101-12108
-
-
McClain, M.S.1
Iwamoto, H.2
Cao, P.3
Vinion-Dubiel, A.D.4
Li, Y.5
Szabo, G.6
Shao, Z.7
Cover, T.L.8
-
29
-
-
0032551711
-
The acid activation of Helicobacter pylori toxin VacA: Structural and membrane binding studies
-
M. Molinari, C. Galli, M. de Bernard, N. Norais, J.M. Ruysschaert, R. Rappuoli, and C. Montecucco The acid activation of Helicobacter pylori toxin VacA: structural and membrane binding studies Biochem. Biophys. Res. Commun. 248 1998 334 340
-
(1998)
Biochem. Biophys. Res. Commun.
, vol.248
, pp. 334-340
-
-
Molinari, M.1
Galli, C.2
De Bernard, M.3
Norais, N.4
Ruysschaert, J.M.5
Rappuoli, R.6
Montecucco, C.7
-
30
-
-
0029559119
-
Lipid interaction of the 37-kDa and 58-kDa fragments of the Helicobacter pylori cytotoxin
-
G. Moll, E. Papini, R. Colonna, D. Burroni, J. Telford, R. Rappuoli, and C. Montecucco Lipid interaction of the 37-kDa and 58-kDa fragments of the Helicobacter pylori cytotoxin Eur. J. Biochem. 234 1995 947 952
-
(1995)
Eur. J. Biochem.
, vol.234
, pp. 947-952
-
-
Moll, G.1
Papini, E.2
Colonna, R.3
Burroni, D.4
Telford, J.5
Rappuoli, R.6
Montecucco, C.7
-
31
-
-
0033962915
-
Structure and interaction of VacA of Helicobacter pylori with a lipid membrane
-
C. Pagliaccia, X.M. Wang, F. Tardy, J.L. Telford, J.M. Ruysschaert, and V. Cabiaux Structure and interaction of VacA of Helicobacter pylori with a lipid membrane Eur. J. Biochem. 267 2000 104 109
-
(2000)
Eur. J. Biochem.
, vol.267
, pp. 104-109
-
-
Pagliaccia, C.1
Wang, X.M.2
Tardy, F.3
Telford, J.L.4
Ruysschaert, J.M.5
Cabiaux, V.6
-
32
-
-
0037057683
-
Helicobacter pylori infection
-
S. Suerbaum, and P. Michetti Helicobacter pylori infection N. Engl. J. Med. 347 2002 1175 1186
-
(2002)
N. Engl. J. Med.
, vol.347
, pp. 1175-1186
-
-
Suerbaum, S.1
Michetti, P.2
-
33
-
-
2442682964
-
Inhibition of primary human T cell proliferation by Helicobacter pylori vacuolating toxin (VacA) is independent of VacA effects on IL-2 secretion
-
M.S. Sundrud, V.J. Torres, D. Unutmaz, and T.L. Cover Inhibition of primary human T cell proliferation by Helicobacter pylori vacuolating toxin (VacA) is independent of VacA effects on IL-2 secretion Proc. Natl. Acad. Sci. USA 101 2004 7727 7732
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 7727-7732
-
-
Sundrud, M.S.1
Torres, V.J.2
Unutmaz, D.3
Cover, T.L.4
-
34
-
-
13044317274
-
Formation of anion-selective channels in the cell plasma membrane by the toxin VacA of Helicobacter pylori is required for its biological activity
-
I. Szabo, S. Brutsche, F. Tombola, M. Moschioni, B. Satin, J.L. Telford, R. Rappuoli, C. Montecucco, E. Papini, and M. Zoratti Formation of anion-selective channels in the cell plasma membrane by the toxin VacA of Helicobacter pylori is required for its biological activity EMBO J. 18 1999 5517 5527
-
(1999)
EMBO J.
, vol.18
, pp. 5517-5527
-
-
Szabo, I.1
Brutsche, S.2
Tombola, F.3
Moschioni, M.4
Satin, B.5
Telford, J.L.6
Rappuoli, R.7
Montecucco, C.8
Papini, E.9
Zoratti, M.10
-
35
-
-
0032981962
-
Helicobacter pylori vacuolating toxin forms anion-selective channels in planar lipid bilayers: Possible implications for the mechanism of cellular vacuolation
-
F. Tombola, C. Carlesso, I. Szabo, M. de Bernard, J.M. Reyrat, J.L. Telford, R. Rappuoli, C. Montecucco, E. Papini, and M. Zoratti Helicobacter pylori vacuolating toxin forms anion-selective channels in planar lipid bilayers: possible implications for the mechanism of cellular vacuolation Biophys. J. 76 1999 1401 1409
-
(1999)
Biophys. J.
, vol.76
, pp. 1401-1409
-
-
Tombola, F.1
Carlesso, C.2
Szabo, I.3
De Bernard, M.4
Reyrat, J.M.5
Telford, J.L.6
Rappuoli, R.7
Montecucco, C.8
Papini, E.9
Zoratti, M.10
-
36
-
-
0030779852
-
Transmembrane beta-barrel of staphylococcal alpha-toxin forms in sensitive but not in resistant cells
-
A. Valeva, I. Walev, M. Pinkernell, B. Walker, H. Bayley, M. Palmer, and S. Bhakdi Transmembrane beta-barrel of staphylococcal alpha-toxin forms in sensitive but not in resistant cells Proc. Natl. Acad. Sci. USA 94 1997 11607 11611
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 11607-11611
-
-
Valeva, A.1
Walev, I.2
Pinkernell, M.3
Walker, B.4
Bayley, H.5
Palmer, M.6
Bhakdi, S.7
-
37
-
-
0029924449
-
Molecular architecture of a toxin pore: A 15-residue sequence lines the transmembrane channel of staphylococcal alpha-toxin
-
A. Valeva, A. Weisser, B. Walker, M. Kehoe, H. Bayley, S. Bhakdi, and M. Palmer Molecular architecture of a toxin pore: a 15-residue sequence lines the transmembrane channel of staphylococcal alpha-toxin EMBO J. 15 1996 1857 1864
-
(1996)
EMBO J.
, vol.15
, pp. 1857-1864
-
-
Valeva, A.1
Weisser, A.2
Walker, B.3
Kehoe, M.4
Bayley, H.5
Bhakdi, S.6
Palmer, M.7
-
38
-
-
0022128222
-
Characteristic views of E. coli and B. stearothermophilus 30S ribosomal subunits in the electron microscope
-
M. van Heel, and M. Stöffler-Meilicke Characteristic views of E. coli and B. stearothermophilus 30S ribosomal subunits in the electron microscope EMBO J. 4 1985 2389 2395
-
(1985)
EMBO J.
, vol.4
, pp. 2389-2395
-
-
Van Heel, M.1
Stöffler-Meilicke, M.2
-
39
-
-
0033621333
-
A dominant negative mutant of Helicobacter pylori vacuolating toxin (VacA) inhibits VacA-induced cell vacuolation
-
A.D. Vinion-Dubiel, M.S. McClain, D.M. Czajkowsky, H. Iwamoto, D. Ye, P. Cao, W. Schraw, G. Szabo, S.R. Blanke, Z. Shao, and T.L. Cover A dominant negative mutant of Helicobacter pylori vacuolating toxin (VacA) inhibits VacA-induced cell vacuolation J. Biol. Chem. 274 1999 37736 37742
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 37736-37742
-
-
Vinion-Dubiel, A.D.1
McClain, M.S.2
Czajkowsky, D.M.3
Iwamoto, H.4
Ye, D.5
Cao, P.6
Schraw, W.7
Szabo, G.8
Blanke, S.R.9
Shao, Z.10
Cover, T.L.11
-
40
-
-
0028341551
-
Identification of a putative membrane-inserted segment in the alpha-toxin of Staphylococcus aureus
-
R.J. Ward, M. Palmer, K. Leonard, and S. Bhakdi Identification of a putative membrane-inserted segment in the alpha-toxin of Staphylococcus aureus Biochemistry 33 1994 7477 7484
-
(1994)
Biochemistry
, vol.33
, pp. 7477-7484
-
-
Ward, R.J.1
Palmer, M.2
Leonard, K.3
Bhakdi, S.4
-
41
-
-
1642431978
-
Helicobacter pylori vacuolating cytotoxin enters cells, localizes to the mitochondria, and induces mitochondrial membrane permeability changes correlated to toxin channel activity
-
D.C. Willhite, and S.R. Blanke Helicobacter pylori vacuolating cytotoxin enters cells, localizes to the mitochondria, and induces mitochondrial membrane permeability changes correlated to toxin channel activity Cell. Microbiol. 6 2004 143 154
-
(2004)
Cell. Microbiol.
, vol.6
, pp. 143-154
-
-
Willhite, D.C.1
Blanke, S.R.2
|