메뉴 건너뛰기




Volumn 6, Issue 1, 2011, Pages 105-120

Potential for serotonergic agents to treat elevated intraocular pressure and glaucoma: Focus on 5-HT2 receptor agonists

Author keywords

eye; glaucoma; intraocular pressure; serotonin

Indexed keywords

(3 CHLOROPHENYL)PIPERAZINE; 1 [5 (2 THIENYLMETHOXY) 3 INDOLYL] 2 PROPANAMINE; 2 DIPROPYLAMINO 8 HYDROXYTETRALIN; 4 IODO 2,5 DIMETHOXYAMPHETAMINE; 6 CHLORO 2 (1 PIPERAZINYL)PYRAZINE; 6 CHLORO 5 METHYL 1 [[2 [(2 METHYL 3 PYRIDYL)OXY] 5 PYRIDYL]CARBAMOYL]INDOLINE; 8 [5 [2,4 DIMETHOXY 5 (4 TRIFLUOROMETHYLPHENYLSULFONAMIDO)PHENYL] 5 OXOPENTYL] 1,3,8 TRIAZASPIRO[4.5]DECANE 2,4 DIONE; AL 34662; AL 6598; ALPHA METHYLSEROTONIN; BETAXOLOL; BRIMONIDINE; BRINZOLAMIDE; CABERGOLINE; CINANSERIN; DORZOLAMIDE; FLESINOXAN; FLUOXETINE; KETANSERIN; PILOCARPINE; PROSTAGLANDIN RECEPTOR STIMULATING AGENT; RITANSERIN; RS 127445; SDZSER 082; SEROTONIN 2 AGONIST; SEROTONIN 2 ANTAGONIST; SEROTONIN 2 RECEPTOR; TRAVOPROST; UNCLASSIFIED DRUG; UNINDEXED DRUG; VOLINANSERIN;

EID: 79951873808     PISSN: 17469899     EISSN: 17469902     Source Type: Journal    
DOI: 10.1586/eop.10.69     Document Type: Review
Times cited : (4)

References (134)
  • 1
    • 77950945877 scopus 로고    scopus 로고
    • New therapies to treat sight loss in an aging population
    • Conroy DM, Acton ML. New therapies to treat sight loss in an aging population. Drug Discov. Today 15, 256-259 (2010).
    • (2010) Drug Discov. Today , vol.15 , pp. 256-259
    • Conroy, D.M.1    Acton, M.L.2
  • 2
    • 72449167431 scopus 로고    scopus 로고
    • Alzheimer's disease and glaucoma: Is there a causal relationship?
    • Wostyn P, Audenaert K, De Deyn PP. Alzheimer's disease and glaucoma: is there a causal relationship? Br. J. Ophthalmol. 93, 1557-1559 (2009).
    • (2009) Br. J. Ophthalmol. , vol.93 , pp. 1557-1559
    • Wostyn, P.1    Audenaert, K.2    De Deyn, P.P.3
  • 3
    • 2442643730 scopus 로고    scopus 로고
    • Primary open angle glaucoma
    • Weinreb RN, Khaw PT. Primary open angle glaucoma. Lancet 363, 1711-1720 (2004).
    • (2004) Lancet , vol.363 , pp. 1711-1720
    • Weinreb, R.N.1    Khaw, P.T.2
  • 4
    • 1842530296 scopus 로고    scopus 로고
    • Causes and Prevalence of Visual Impairment among Adults in the United States
    • DOI 10.1001/archopht.122.4.477
    • Congdon N, O'Colmain B, Klaver CC et al. Causes and prevalence of visual impairment among (Pubitemid 38456282)
    • (2004) Archives of Ophthalmology , vol.122 , Issue.4 , pp. 477-485
    • Congdon, N.1
  • 6
    • 33644655886 scopus 로고    scopus 로고
    • The number of people with glaucoma worldwide in 2010 and 2020
    • DOI 10.1136/bjo.2005.081224
    • Quigley HA, Broman AT. The number of people with glaucoma worldwide in 2010 and 2020. Br. J. Ophthalmol. 90, 262-267 (2006). (Pubitemid 43325451)
    • (2006) British Journal of Ophthalmology , vol.90 , Issue.3 , pp. 262-267
    • Quigley, H.1    Broman, A.T.2
  • 7
    • 56549118858 scopus 로고    scopus 로고
    • Risk factors for glaucoma onset and progression
    • Coleman AL, Miglior S. Risk factors for glaucoma onset and progression. Surv. Ophthalmol. 53, S3-S10 (2008).
    • (2008) Surv. Ophthalmol. , vol.53
    • Coleman, A.L.1    Miglior, S.2
  • 8
    • 35848942149 scopus 로고    scopus 로고
    • What Increases Outflow Resistance in Primary Open-angle Glaucoma?
    • DOI 10.1016/j.survophthal.2007.08.002, PII S0039625707001798
    • Tamm ER, Fuchshofer R. What increases outflow resistance in primary open-angle glaucoma? Surv. Ophthalmol. 52(Suppl. 2), S101-S104 (2007). (Pubitemid 350060958)
    • (2007) Survey of Ophthalmology , vol.52 , Issue.SUPPL.
    • Tamm, E.R.1    Fuchshofer, R.2
  • 9
    • 64249131959 scopus 로고    scopus 로고
    • The trabecular meshwork outflow pathways: Structural and functional aspects
    • Tamm ER. The trabecular meshwork outflow pathways: structural and functional aspects. Exp. Eye Res. 88, 648-655 (2009).
    • (2009) Exp. Eye Res. , vol.88 , pp. 648-655
    • Tamm, E.R.1
  • 10
    • 64249083215 scopus 로고    scopus 로고
    • Uveoscleral outflow -A review
    • Alm A, Nilsson SF. Uveoscleral outflow -a review. Exp. Eye Res. 88, 760-768 (2009).
    • (2009) Exp. Eye Res. , vol.88 , pp. 760-768
    • Alm, A.1    Nilsson, S.F.2
  • 11
    • 41049089213 scopus 로고    scopus 로고
    • Extracellular matrix turnover and outflow resistance
    • Acott TS, Kelley MJ. Extracellular matrix turnover and outflow resistance. Exp. Eye Res. 86, 543-561 (2008).
    • (2008) Exp. Eye Res. , vol.86 , pp. 543-561
    • Acott, T.S.1    Kelley, M.J.2
  • 13
    • 33646938250 scopus 로고    scopus 로고
    • Recent developments in understanding the pathophysiology of elevated intraocular pressure
    • DOI 10.1016/j.csr.2005.09.008, PII 0005573520060400000009
    • Tan, JCH, Peters DM, Kaufman PL. Recent developments in understanding the pathophysiology of elevated intraocular pressure. Curr. Opin. Ophthalmol. 17, 168-174 (2006). (Pubitemid 43790813)
    • (2006) Current Opinion in Ophthalmology , vol.17 , Issue.2 , pp. 168-174
    • Tan, J.C.H.1    Peters, D.M.2    Kaufman, P.L.3
  • 15
    • 31344441760 scopus 로고    scopus 로고
    • Glutamate level in optic nerve head is increased by artificial elevation of intraocular pressure in rabbits
    • DOI 10.1016/j.exer.2005.08.004, PII S0014483505002460
    • Okuno T, Oku H, Sugiyama T, Ikeda T. Glutamate level in optic nerve head is increased by artificial elevation of intraocular pressure in rabbits. Exp. Eye Res. 82, 465-470 (2006). (Pubitemid 43138960)
    • (2006) Experimental Eye Research , vol.82 , Issue.3 , pp. 465-470
    • Okuno, T.1    Oku, H.2    Sugiyama, T.3    Ikeda, T.4
  • 16
    • 0036278328 scopus 로고    scopus 로고
    • Endothelin: Is it a contributor to glaucoma pathophysiology?
    • Yorio T, Krishnamoorthy R, Prasanna G. Endothelin: is it a contributor to glaucoma pathophysiology? J. Glaucoma 11, 259-270 (2002). (Pubitemid 34620104)
    • (2002) Journal of Glaucoma , vol.11 , Issue.3 , pp. 259-270
    • Yorio, T.1    Krishnamoorthy, R.2    Prasanna, G.3
  • 17
    • 0020656514 scopus 로고
    • Blockage of axonal transport in optic nerve induced by elevation of intraocular pressure. Effect of arterial hypertension induced by angiotensin I
    • Sossi N, Anderson DR. Blockage of axonal transport in optic nerve induced by elevation of intraocular pressure. Effect of arterial hypertension induced by angiotensin I. Arch. Ophthalmol. 101, 94-97 (1983). (Pubitemid 13167179)
    • (1983) Archives of Ophthalmology , vol.101 , Issue.1 , pp. 94-97
    • Sossi, N.1    Anderson, D.R.2
  • 20
    • 61449140114 scopus 로고    scopus 로고
    • Primary open-angle glaucoma: Diagnostic approaches and management
    • Hazin R, Hendrick AM, Kahook MY. Primary open-angle glaucoma: diagnostic approaches and management. J. Natl Med. Assoc. 101, 46-50 (2009).
    • (2009) J. Natl Med. Assoc. , vol.101 , pp. 46-50
    • Hazin, R.1    Hendrick, A.M.2    Kahook, M.Y.3
  • 21
    • 0038132019 scopus 로고    scopus 로고
    • Ophthalmic drug discovery
    • DOI 10.1038/nrd1106
    • Clark AF, Yorio T. Ophthalmic drug discovery. Nat. Rev. Drug Discov. 2, 448-459 (2003). (Pubitemid 37361726)
    • (2003) Nature Reviews Drug Discovery , vol.2 , Issue.6 , pp. 448-459
    • Clark, A.F.1    Yorio, T.2
  • 24
    • 50249138163 scopus 로고    scopus 로고
    • Pharmacological management of primary open-angle glaucoma: Second-line options and beyond
    • Webers CA, Beckers HJ, Nuijts RM, Schouten JS. Pharmacological management of primary open-angle glaucoma: second-line options and beyond. Drugs Aging 25, 729-759 (2008).
    • (2008) Drugs Aging , vol.25 , pp. 729-759
    • Webers, C.A.1    Beckers, H.J.2    Nuijts, R.M.3    Schouten, J.S.4
  • 26
    • 73149117367 scopus 로고    scopus 로고
    • Pharmacotherapy of intraocular pressure: Part II. Carbonic anhydrase inhibitors, prostaglandin analogues and prostamides
    • Costagliola C, dell'Omo R, Romano MR, Rinaldi M, Zeppa L, Parmeggiani F. Pharmacotherapy of intraocular pressure: part II. Carbonic anhydrase inhibitors, prostaglandin analogues and prostamides. Expert Opin. Pharmacother. 10, 2859-2870 (2009).
    • (2009) Expert Opin. Pharmacother. , vol.10 , pp. 2859-2870
    • Costagliola, C.1    Dell'Omo, R.2    Romano, M.R.3    Rinaldi, M.4    Zeppa, L.5    Parmeggiani, F.6
  • 27
    • 40949133026 scopus 로고    scopus 로고
    • Glaucoma: A review of adjunctive therapy and new management strategies
    • Whitson JT. Glaucoma: a review of adjunctive therapy and new management strategies. Expert Opin. Pharmacother. 8, 3237-3249 (2007).
    • (2007) Expert Opin. Pharmacother. , vol.8 , pp. 3237-3249
    • Whitson, J.T.1
  • 28
    • 69249214004 scopus 로고    scopus 로고
    • Brimonidine tartrate 0.15%, dorzolamide hydrochloride 2%, and brinzolamide 1% compared as adjunctive therapy to prostaglandin analogs
    • Bournias TE, Lai J. Brimonidine tartrate 0.15%, dorzolamide hydrochloride 2%, and brinzolamide 1% compared as adjunctive therapy to prostaglandin analogs. Ophthalmology 116, 1719-1724 (2009).
    • (2009) Ophthalmology , vol.116 , pp. 1719-1724
    • Bournias, T.E.1    Lai, J.2
  • 29
    • 77950354281 scopus 로고    scopus 로고
    • Clinical efficacy and neuroprotective effects of brimonidine in the management of glaucoma and ocular hypertension
    • Galanopoulos A, Goldberg I. Clinical efficacy and neuroprotective effects of brimonidine in the management of glaucoma and ocular hypertension. Clin. Ophthalmol. 3, 117-122 (2009).
    • (2009) Clin. Ophthalmol. , vol.3 , pp. 117-122
    • Galanopoulos, A.1    Goldberg, I.2
  • 30
    • 40349103258 scopus 로고    scopus 로고
    • History of neuroprotection and rationale as a therapy for glaucoma
    • Levins LA, Peeples P. History of neuroprotection and rationale as a therapy for glaucoma. Am. J. Manag. Care 14, S11-S14 (2008). (Pubitemid 351341923)
    • (2008) American Journal of Managed Care , vol.14 , Issue.SUPPL. 1
    • Levin, L.A.1    Peeples, P.2
  • 31
    • 66249085210 scopus 로고    scopus 로고
    • Recent clinical findings with memantine should not mean that the idea of neuroprotection in glaucoma is abandoned
    • Osborne NN. Recent clinical findings with memantine should not mean that the idea of neuroprotection in glaucoma is abandoned. Acta Ophthalmol. 87, 450-454 (2009).
    • (2009) Acta Ophthalmol. , vol.87 , pp. 450-454
    • Osborne, N.N.1
  • 32
    • 0019195457 scopus 로고
    • Retinal indolamine accumulating neurons
    • Ehinger B, Floren I. Retinal indolamine accumulating neurons. Neurochem. Int. 1, 209-229 (1980).
    • (1980) Neurochem. Int. , vol.1 , pp. 209-229
    • Ehinger, B.1    Floren, I.2
  • 33
    • 0019506399 scopus 로고
    • Serotonin nerve endings and regulation of pupillary diameter
    • Moro F, Scapagnin U, Scaletta S, Drago F. Serotonin nerve endings in the regulation of papillary diameter. Ann. Ophthalmol. 13, 487-490 (1981). (Pubitemid 11096999)
    • (1981) Annals of Ophthalmology , vol.13 , Issue.4 , pp. 487-490
    • Moro, R.1    Scapagnini, U.2    Scaletta, S.3    Drago, F.4
  • 34
    • 0023723116 scopus 로고
    • Evidence for presence of serotonergic nerves and receptors in the iris-ciliary body complex of the rabbit
    • Tobin AB, Unger W, Osborne NN. Evidence for presence of serotonergic nerves and receptors in the iris-ciliary body complex of the rabbit. J. Neurosci. 8, 3713-3721 (1988).
    • (1988) J. Neurosci. , vol.8 , pp. 3713-3721
    • Tobin, A.B.1    Unger, W.2    Osborne, N.N.3
  • 35
    • 85007742480 scopus 로고
    • Morphological characterization and distribution of indolamine- accumulating cells in the rat retina
    • Matsumoto Y, Ueda S, Kawata M. Morphological characterization and distribution of indolamine-accumulating cells in the rat retina. Acta Histochem. Cytochem. 25, 45-51 (1992).
    • (1992) Acta Histochem. Cytochem. , vol.25 , pp. 45-51
    • Matsumoto, Y.1    Ueda, S.2    Kawata, M.3
  • 36
    • 0023137555 scopus 로고
    • An indoleamine system in photoreceptor cell terminals of the Long-Evans rat retina
    • Redburn DA, Churchill L. An indoleamine system in photoreceptor cell terminals of the Long-Evans rat retina. J. Neurosci. 7, 319-329 (1987). (Pubitemid 17017462)
    • (1987) Journal of Neuroscience , vol.7 , Issue.2 , pp. 319-329
    • Redburn, D.A.1    Churchill, L.2
  • 40
    • 0023187478 scopus 로고
    • Levels of norepinephrine, epinephrine, dopamine, serotonin and N-acetylserotonin in aqueous humour
    • Trope GE, Sole M, Aedy L, Madapallimattam A. Levels of norepinephrine, epinephrine, dopamine, serotonin and N-acetylserotonin in aqueous humor. Can. J. Ophthalmol. 22, 152-154 (1987). (Pubitemid 17111513)
    • (1987) Canadian Journal of Ophthalmology , vol.22 , Issue.3 , pp. 152-154
    • Trope, G.E.1    Sole, M.2    Aedy, L.3    Madapallimattam, A.4
  • 43
    • 0343390317 scopus 로고    scopus 로고
    • 5-HT1A and 5-HT7 receptor expression in the mammalian retina
    • Pootanakit K, Brunken WJ. 5-HT1A and 5-HT7 receptor expression in the mammalian retina. Brain Res. 875, 152-156 (2002).
    • (2002) Brain Res. , vol.875 , pp. 152-156
    • Pootanakit, K.1    Brunken, W.J.2
  • 44
    • 0032587910 scopus 로고    scopus 로고
    • 5-HT(2a) receptors in the rabbit retina: Potential presynaptic modulators
    • DOI 10.1017/S0952523899162035
    • Pootanakit K, Prior KJ, Hunter DJ, Brunken WJ. 5-HT2A receptors in the rabbit retina: potential presynaptic modulators. Vis. Neurosci. 16, 221-230 (1999). (Pubitemid 29188116)
    • (1999) Visual Neuroscience , vol.16 , Issue.2 , pp. 221-230
    • Pootanakit, K.1    Prior, K.J.2    Hunter, D.D.3    Brunken, W.J.4
  • 45
    • 0032889809 scopus 로고
    • Serotonin-2A receptor mRNA expression in rat retinal pigment epithelial cells
    • Nash M, Flanigan T, Leslie R, Osborne NN. Serotonin-2A receptor mRNA expression in rat retinal pigment epithelial cells. Ophthalmic Res. 31, 1-4 (1993).
    • (1993) Ophthalmic Res. , vol.31 , pp. 1-4
    • Nash, M.1    Flanigan, T.2    Leslie, R.3    Osborne, N.N.4
  • 46
    • 0142231546 scopus 로고    scopus 로고
    • Characterization of serotonergic receptors in rabbit, porcine and human conjunctivae
    • DOI 10.1076/ceyr.27.4.205.16600
    • Turner HC, Alvarez LJ, Candia OA, Bernstein AM. Characterization of serotonergic receptors in rabbit, porcine and human conjunctivae. Curr. Eye Res. 27, 205-215 (2003). (Pubitemid 37315479)
    • (2003) Current Eye Research , vol.27 , Issue.4 , pp. 205-215
    • Turner, H.C.1    Alvarez, L.J.2    Candia, O.A.3    Bernstein, A.M.4
  • 47
    • 0032324763 scopus 로고    scopus 로고
    • 7 receptors in rabbit ocular and brain tissues
    • DOI 10.1016/S0306-4522(98)00181-X, PII S030645229800181X
    • Chidlow G, Le Corre, Osborne NN. Localization of 5-hydroxytryptamine-1A and 5-hydroxytryptamine-7 receptors in rabbit ocular and brain tissues. Neuroscience 87, 675-689 (1998). (Pubitemid 28396553)
    • (1998) Neuroscience , vol.87 , Issue.3 , pp. 675-689
    • Chidlow, G.1    Le Corre, S.2    Osborne, N.N.3
  • 48
    • 1842728388 scopus 로고    scopus 로고
    • Expression of serotonin receptor mRNAs in human ciliary body: A polymerase chain reaction study
    • DOI 10.1007/s00417-003-0785-7
    • Chidlow G, Hiscott PS, Osborne NN. Expression of serotonin receptor mRNAs in human ciliary body: a polymerase chain reaction study. Graefe's Arch. Clin. Exp. Ophthalmol. 242, 259-264 (2004). (Pubitemid 38477213)
    • (2004) Graefe's Archive for Clinical and Experimental Ophthalmology , vol.242 , Issue.3 , pp. 259-264
    • Chidlow, G.1    Hiscott, P.S.2    Osborne, N.N.3
  • 49
    • 33748416317 scopus 로고    scopus 로고
    • Serotonin receptor subtype mRNA expression in human ocular tissues, determined by RT-PCR
    • Sharif NA, Senchyna M. Serotonin receptor subtype mRNA expression in human ocular tissues determined by RT-PCR. Mol. Vis. 12, 1040-1047 (2006). (Pubitemid 44340518)
    • (2006) Molecular Vision , vol.12 , pp. 1040-1047
    • Sharif, N.A.1    Senchyna, M.2
  • 50
    • 0023121581 scopus 로고
    • Characterization of serotonin receptors in the iris + ciliary body of the albino rat
    • Mallorga P, Sugrue MF. Characterization of serotonin receptors in the iris-ciliary body of the albino rabbit. Curr. Eye Res. 6, 527-532 (1987). (Pubitemid 17039764)
    • (1987) Current Eye Research , vol.6 , Issue.3 , pp. 527-532
    • Mallorga, P.1    Sugrue, M.F.2
  • 52
    • 0028971437 scopus 로고
    • Characteristics of [3H]-5-hydroxytryptamine binding to iris-ciliary body tissue of the rabbit
    • Chidlow G, DeSantis LM, Sharif NA, Osborne NN. Characteristics of [3H]-5-hydroxytryptamine binding to iris-ciliary body tissue of the rabbit. Invest. Ophthalmol. Vis. Sci. 36, 2238-2245 (1995).
    • (1995) Invest. Ophthalmol. Vis. Sci. , vol.36 , pp. 2238-2245
    • Chidlow, G.1    Desantis, L.M.2    Sharif, N.A.3    Osborne, N.N.4
  • 53
    • 33748436596 scopus 로고    scopus 로고
    • 2) receptor-mediated signal transduction in human ciliary muscle cells: Role in ocular hypotension
    • DOI 10.1089/jop.2006.22.389
    • Sharif NA, Kelly CR, Crider JY, Davis TL. Serotonin-2 (5-HT2) receptor-mediated signal transduction in human ciliary muscle cells: role in ocular hypotension. J. Ocul. Pharmacol. Ther. 22, 389-401 (2006). (Pubitemid 46106477)
    • (2006) Journal of Ocular Pharmacology and Therapeutics , vol.22 , Issue.6 , pp. 389-401
    • Sharif, N.A.1    Kelly, C.R.2    Crider, J.Y.3    Davis, T.L.4
  • 55
    • 0022416985 scopus 로고
    • Indoleamine-sensitive adenylate cyclase in rabbit retina: Characterization and distribution
    • DOI 10.1111/j.1471-4159.1985.tb04007.x
    • Blazynski C, Ferrendelli JA, Cohen AI. Indolamine-sensitive adenylate cyclase in rabbit retina: characterization and distribution. J. Neurochem. 45, 440-447 (1985). (Pubitemid 15233943)
    • (1985) Journal of Neurochemistry , vol.45 , Issue.2 , pp. 440-447
    • Blazynski, C.1    Ferrendelli, J.A.2    Cohen, A.I.3
  • 56
    • 0023178344 scopus 로고
    • 4 turnover in rabbit cornea
    • Akhtar RA. Effects of norepinephrine and 5-hydroxytryptamine on phosphoinositide-PO4 turnover in rabbit cornea. Exp. Eye Res. 44, 849-862 (1987). (Pubitemid 17113224)
    • (1987) Experimental Eye Research , vol.44 , Issue.6 , pp. 849-862
    • Akhtar, R.A.1
  • 57
    • 0023621225 scopus 로고
    • Serotonergic and cholinergic stimulation of inositol phosphate formation in the rabbit retina. Evidence for the presence of serotonin and muscarinic receptors
    • Cutcliffe N, Osborne NN. Serotonergic and cholinergic stimulation of inositol phosphate formation in the rabbit retina. Evidence for the presence of serotonin and muscarinic receptors. Brain Res. 421, 95-104 (1987). (Pubitemid 18021617)
    • (1987) Brain Research , vol.421 , Issue.1-2 , pp. 95-104
    • Cutcliffe, N.1    Osborne, N.N.2
  • 58
    • 0027304897 scopus 로고
    • 1) receptors negatively coupled to adenylate cyclase in rabbit and human iris-ciliary processes
    • DOI 10.1006/exer.1993.1116
    • Barnett NL, Osborne NN. The presence of serotonin (5-HT1) receptor negatively coupled to adenylate cyclase in rabbit and human iris-ciliary process. Exp. Eye Res. 57, 209-216 (1993). (Pubitemid 23252714)
    • (1993) Experimental Eye Research , vol.57 , Issue.2 , pp. 209-216
    • Barnett, N.L.1    Osborne, N.N.2
  • 59
    • 0024391794 scopus 로고
    • Evidence for the presence of serotonin receptors negatively coupled to adenylate cyclase in the rabbit iris-ciliary body
    • Tobin AB, Osborne NN. Evidence for the presence of serotonin receptors negatively coupled to adenylate cyclase in the rabbit iris-ciliary body. J. Neurochem. 53, 686-691 (1989). (Pubitemid 19207358)
    • (1989) Journal of Neurochemistry , vol.53 , Issue.3 , pp. 686-691
    • Tobin, A.B.1    Osborne, N.N.2
  • 60
    • 0026093812 scopus 로고
    • 5-HT1A receptors positively coupled to cAMP formation in the rabbit retina
    • Osborne NN, Ghazi H. 5-HT1A receptors positively coupled to cAMP formation in the rabbit retina. Neurochem. Int. 19, 407-511 (1991).
    • (1991) Neurochem. Int. , vol.19 , pp. 407-511
    • Osborne, N.N.1    Ghazi, H.2
  • 61
    • 0027330347 scopus 로고
    • 2, receptor-mediated phosphoinositide turnover and mobilization of calcium in cultured rat retinal pigment epithelium cells
    • DOI 10.1016/0042-6989(93)90097-G
    • Osborne NN, Fitzgibbon F, Nash M, Liu NP, Leslie R, Cholewinski A. Serotonergic, 5-HT2, receptor-mediated phosphoinositide turnover and mobilization of calcium in cultured rat retinal pigment epithelium cells. Vis. Res. 33, 2171-2179 (1993). (Pubitemid 23266215)
    • (1993) Vision Research , vol.33 , Issue.16 , pp. 2171-2179
    • Osborne, N.N.1    Fitzgibbon, F.2    Nash, M.3    Liu, N.-P.4    Leslie, R.5    Cholewinski, A.6
  • 64
  • 67
    • 0037424557 scopus 로고    scopus 로고
    • 3 receptors in the bovine ciliary muscle
    • DOI 10.1016/S0014-2999(03)01320-7
    • Lograno MS, Romano MR. Pharmacological characterization of the 5-HT1A, 5-HT2 and 5-HT3 receptors in the bovine ciliary muscle. Eur. J. Pharmacol. 464, 69-74 (2003). (Pubitemid 36205067)
    • (2003) European Journal of Pharmacology , vol.464 , Issue.1 , pp. 69-74
    • Lograno, M.D.1    Romano, M.R.2
  • 68
    • 0026826302 scopus 로고
    • The effects of serotonin drugs on horizontal and ganglion cells in the rabbit retina
    • Mangel SS, Brunken WJ. The effects of serotonin drugs on horizontal and ganglion cells in the rabbit retina. Vis. Neurosci. 8, 213-218 (1992).
    • (1992) Vis. Neurosci. , vol.8 , pp. 213-218
    • Mangel, S.S.1    Brunken, W.J.2
  • 69
    • 0027472292 scopus 로고
    • The properties of the serotonergic system in the retina
    • Brunken WJ, Jin XT, Pis-Lopez AM. The properties of the serotonergic system in the retina. Prog. Ret. Res. 16, 75-99 (1993).
    • (1993) Prog. Ret. Res. , vol.16 , pp. 75-99
    • Brunken, W.J.1    Jin, X.T.2    Pis-Lopez, A.M.3
  • 70
    • 0027601193 scopus 로고
    • A role for 5-HT3 receptors in visual processing in the mammalian retina
    • Brunken WJ, Jin XT. A role for 5-HT3 receptors in visual processing in the mammalian retina. Vis. Neurosci. 10, 511-522 (1993).
    • (1993) Vis. Neurosci. , vol.10 , pp. 511-522
    • Brunken, W.J.1    Jin, X.T.2
  • 71
    • 0024182046 scopus 로고
    • The effects of serotonin agonists and antagonists on the response properties of complex ganglion cells of the rabbit retina
    • Brunken WJ, Daw NW. The effects of serotonin agonists and antagonists on the response properties of complex ganglion cells of the rabbit retina. Vis. Neurosci. 1, 181-188 (1988).
    • (1988) Vis. Neurosci. , vol.1 , pp. 181-188
    • Brunken, W.J.1    Daw, N.W.2
  • 73
    • 0015952018 scopus 로고
    • Effects of intravenous infusions of histamine, 5-hydroxytryptamine, bradykinin and prostaglandins on intraocular pressure
    • Chiang TS. Effects of intravenous infusions of histamine, 5-hydroxytryptamine, bradykinin and prostaglandins on intraocular pressure. Arch. Int. Pharmacodyn. Ther. 207, 131-138 (1974).
    • (1974) Arch. Int. Pharmacodyn. Ther. , vol.207 , pp. 131-138
    • Chiang, T.S.1
  • 74
    • 3042517006 scopus 로고    scopus 로고
    • SSRIs and intraocular pressure modifications: Evidence, therapeutic implications and possible mechanisms
    • DOI 10.2165/00023210-200418080-00001
    • Costagliola C, Parmeggiani F, Sebastiani A. SSRIs and intraocular pressure modifications: evidence, therapeutic implications and possible mechanisms. CNS Drugs 18, 475-484 (2004). (Pubitemid 38829944)
    • (2004) CNS Drugs , vol.18 , Issue.8 , pp. 475-484
    • Costagliola, C.1    Parmeggiani, F.2    Sebastiani, A.3
  • 75
    • 0023547656 scopus 로고
    • Effect of serotonin and its antagonist (ketanserin) on intraocular pressure in the rabbit
    • Krootila K, Palkama A, Uusitalo H. Effects of serotonin and its antagonist (ketanserin) on intraocular pressure in the rabbit. J. Ocul. Pharmacol. 3, 279-290 (1987). (Pubitemid 18063029)
    • (1987) Journal of Ocular Pharmacology , vol.3 , Issue.4 , pp. 279-290
    • Krootila, K.1    Palkama, A.2    Uusitalo, H.3
  • 77
    • 0032775497 scopus 로고    scopus 로고
    • 8OH-DPAT-induced ocular hypotension: Sites and mechanisms of action
    • DOI 10.1006/exer.1999.0694
    • Chu TC, Ogidigben MJ, Potter DE. 8-OH-DPAT-induced ocular hypotension: sites and mechanisms of action. Exp. Eye Res. 69, 227-238 (1999). (Pubitemid 29369296)
    • (1999) Experimental Eye Research , vol.69 , Issue.2 , pp. 227-238
    • Chu, T.-C.1    Ogidigben, M.J.2    Potter, D.E.3
  • 78
    • 0033383538 scopus 로고    scopus 로고
    • The 5-HT(1A) receptor agonist 8-OH-DPAT lowers intraocular pressure in normotensive NZW rabbits
    • DOI 10.1006/exer.1999.0756
    • Chidlow G, Nash MS, DeSantis L, Osborne NN. The 5-HT1A receptor agonist 8-OH-DPAT lowers intraocular pressure in normotensive NZW rabbits. Exp. Eye Res. 69, 587-593 (1999). (Pubitemid 30046883)
    • (1999) Experimental Eye Research , vol.69 , Issue.6 , pp. 587-593
    • Chidlow, G.1    Nash, M.S.2    De Santis, L.M.3    Osborne, N.N.4
  • 79
    • 0035436707 scopus 로고    scopus 로고
    • 1- adrenoceptor antagonist, lowers intraocular pressure in NZW rabbits
    • DOI 10.1076/ceyr.23.2.144.5480
    • Chidlow G, Cupido A, Melena J, Osborne NN. Flesinoxan, a 5-HT1A receptor agonist/5-HT1-adrenoceptor antagonist, lowers intraocular pressure in NZW rabbits. Curr. Eye Res. 23, 144-153 (2001). (Pubitemid 34499638)
    • (2001) Current Eye Research , vol.23 , Issue.2 , pp. 144-153
    • Chidlow, G.1    Cupido, A.2    Melena, J.3    Osborne, N.N.4
  • 82
    • 0026696862 scopus 로고
    • Ocular hypotensive actions of serotonin antagonist-ketanserin and analogs
    • Chiou GC, Li BH. Ocular hypotensive actions of serotonin antagonist-ketanserin and analogs. J. Ocular Pharmacol. Ther. 8, 11-21 (1992).
    • (1992) J. Ocular Pharmacol. Ther. , vol.8 , pp. 11-21
    • Chiou, G.C.1    Li, B.H.2
  • 85
    • 0035652730 scopus 로고    scopus 로고
    • Effect of ketanserin administration on intraocular pressure
    • DOI 10.1159/000050901
    • Takat D, Guler C, Arici M, Topalkara A, Erdogan H. Effect of ketanserin administration on intraocular pressure. Ophthalmologica 215, 419-423 (2001). (Pubitemid 34008788)
    • (2001) Ophthalmologica , vol.215 , Issue.6 , pp. 419-423
    • Tekat, D.1    Guler, C.2    Arici, M.K.3    Topalkara, A.4    Erdogan, H.5
  • 86
    • 0012133788 scopus 로고
    • The effect of anplag (sarpogrelate HCl), novel selective 5-HT2 antagonist on intraocular pressure in glaucoma patients
    • Takenaka H, Mano T, Maeno T, Okada M, Okano Y, Mitsuka M. The effect of anplag (sarpogrelate HCl), novel selective 5-HT2 antagonist on intraocular pressure in glaucoma patients. Invest. Ophthalmol. Vis. Sci. 36, S734 (1995).
    • (1995) Invest. Ophthalmol. Vis. Sci. , vol.36
    • Takenaka, H.1    Mano, T.2    Maeno, T.3    Okada, M.4    Okano, Y.5    Mitsuka, M.6
  • 90
    • 0036119338 scopus 로고    scopus 로고
    • Molecular, pharmacological and functional diversity of 5-HT receptors
    • DOI 10.1016/S0091-3057(01)00746-8, PII S0091305701007468
    • Hoyer D, Hannon JP, Martin GR. Molecular, pharmacological and functional diversity of 5-HT receptors. Pharmacol. Biochem. Behav. 71, 533-554 (2002). (Pubitemid 34219205)
    • (2002) Pharmacology Biochemistry and Behavior , vol.71 , Issue.4 , pp. 533-554
    • Hoyer, D.1    Hannon, J.P.2    Martin, G.R.3
  • 91
    • 0026006805 scopus 로고
    • Effect of bunazosin hydrochloride on intraocular pressure and aqueous humor dynamics in normotensive human eyes
    • Oshika T, Araie A, Sugiyama T, Nakajima M, Azuma I. Effect of bunazosin hydrochloride on intraocular pressure and aqueous humor dynamics in normotensive human eyes. Arch. Ophthalmol. 109, 1569-1574 (1991).
    • (1991) Arch. Ophthalmol. , vol.109 , pp. 1569-1574
    • Oshika, T.1    Araie, A.2    Sugiyama, T.3    Nakajima, M.4    Azuma, I.5
  • 92
    • 0030743820 scopus 로고    scopus 로고
    • Effect of 5-methylurapidil, an α(1a)-adrenergic antagonist and 5-hydroxytryptamine(1a) agonist, on aqueous humor dynamics in monkeys and rabbits
    • DOI 10.1076/ceyr.16.8.769.8988
    • Wang RF, Lee PY, Mittag TW, Podos SM, Serle JB. Effect of 5-methyl-urapidil, an a-1a-adrenergic antagonist and 5-hydroxytrptamine-1A agonist, on aqueous humor dynamics in monkeys and rabbits. Curr. Eye Res. 16, 769-775 (1997). (Pubitemid 27354975)
    • (1997) Current Eye Research , vol.16 , Issue.8 , pp. 769-775
    • Wang, R.-F.1    Lee, P.-Y.2    Mittag, T.W.3    Podos, S.M.4    Serle, J.B.5
  • 93
    • 0034937635 scopus 로고    scopus 로고
    • Affinity of serotonin receptor antagonists and agonists to recombinant and native a1-adrenoceptor subtypes
    • Yoshio R, Taniguchi T, Itoh H, Muramatsu I. Affinity of serotonin receptor antagonists and agonists to recombinant and native a1-adrenoceptor subtypes. Jpn J. Pharmacol. 86, 189-195 (2001).
    • (2001) Jpn J. Pharmacol. , vol.86 , pp. 189-195
    • Yoshio, R.1    Taniguchi, T.2    Itoh, H.3    Muramatsu, I.4
  • 94
    • 33947403538 scopus 로고    scopus 로고
    • AL-34662: A potent, selective, and efficacious ocular hypotensive serotonin-2 receptor agonist
    • DOI 10.1089/jop.2006.0093
    • Sharif NA, McLaughlin MA, Kelly CR. AL-34662: a potent, selective and efficacious ocular hypotensive serotonin-2 receptor agonist. J. Ocular Pharmacol. Ther. 23, 1-13 (2007). (Pubitemid 46449294)
    • (2007) Journal of Ocular Pharmacology and Therapeutics , vol.23 , Issue.1 , pp. 1-13
    • Sharif, N.A.1    McLaughlin, M.A.2    Kelly, C.R.3
  • 96
    • 0141566616 scopus 로고    scopus 로고
    • 2 receptor agonist with ocular hypotensive activity: (S)-(+)-1-(2-aminopropyl)-8,9-dihydropyrano[3,2-e]indole
    • DOI 10.1021/jm030205t
    • May JM, Chen H-H, Rusinko A, Lynch VM, Sharif NA, McLaughlin MA. A novel and selective 5-HT2 receptor agonist with ocular hypotensive activity: (S)-(+)-1-(2-aminopropyl)-8,9-dihydropyrano-[3,2-e] indole. J. Med. Chem. 46, 4188-4195 (2003). (Pubitemid 37122461)
    • (2003) Journal of Medicinal Chemistry , vol.46 , Issue.19 , pp. 4188-4195
    • May, J.A.1    Chen, H.-H.2    Rusinko, A.3    Lynch, V.M.4    Sharif, N.A.5    McLaughlin, M.A.6
  • 97
    • 61549104131 scopus 로고    scopus 로고
    • Cabergoline: Pharmacology, ocular hypotensive studies in multiple species, and aqueous humor dynamic modulation in cynomolgus monkey eyes
    • Sharif NA, McLaughlin, MA, Kelly CR et al. Cabergoline: pharmacology, ocular hypotensive studies in multiple species, and aqueous humor dynamic modulation in cynomolgus monkey eyes. Exp. Eye Res. 88, 386-397 (2006).
    • (2006) Exp. Eye Res. , vol.88 , pp. 386-397
    • Sharif, N.A.1    McLaughlin, M.A.2    Kelly, C.R.3
  • 100
    • 0030431577 scopus 로고    scopus 로고
    • Preclinical characterization of the potential of the putative atypical antipsychotic MDL 100,907 as a potent 5-HT2A antagonist with a favorable CNS safety profile
    • Kehne JH, Baron BM, Carr AA et al. Preclinical characterization of the potential of the putative atypical antipsychotic MDL 100,907 as a potent 5-HT2A antagonist with a favorable CNS safety profile. J. Pharmacol. Exp. Ther. 277, 968-981 (1996).
    • (1996) J. Pharmacol. Exp. Ther. , vol.277 , pp. 968-981
    • Kehne, J.H.1    Baron, B.M.2    Carr, A.A.3
  • 101
    • 0030087741 scopus 로고    scopus 로고
    • Pharmacologic characterization of the human 5-hydroxytryptamine2B receptor: Evidence for species differences
    • .101 Wainscott DB, Lucaites VL, Kursar JD, Baez M, Nelson DL. Pharmacologic characterization of the human 5-hydroxytryptamine2B receptor: evidence for species differences. J. Pharmacol. Exp. Ther. 276, 720-726 (1996).
    • (1996) J. Pharmacol. Exp. Ther. , vol.276 , pp. 720-726
    • Wainscott, D.B.1    Lucaites, V.L.2    Kursar, J.D.3    Baez, M.4    Nelson, D.L.5
  • 107
    • 0034002380 scopus 로고    scopus 로고
    • The regulation of trabecular meshwork and ciliary muscle contractility
    • DOI 10.1016/S1350-9462(99)00015-4, PII S1350946299000154
    • Wiederholt M, Thieme H, Stumpff F. The regulation of trabecular meshwork and ciliary muscle contractility. Prog. Retinal Eye Res. 19, 271-295 (2000). (Pubitemid 30122724)
    • (2000) Progress in Retinal and Eye Research , vol.19 , Issue.3 , pp. 271-295
    • Wiederholt, M.1    Thieme, H.2    Stumpff, F.3
  • 108
    • 64249118693 scopus 로고    scopus 로고
    • Mechanobiology of trabecular meshwork cells
    • WuDunn D. Mechanobiology of trabecular meshwork cells. Exp. Eye Res. 88, 718-723 (2009).
    • (2009) Exp. Eye Res. , vol.88 , pp. 718-723
    • Wudunn, D.1
  • 110
    • 0034741547 scopus 로고    scopus 로고
    • Levobetaxolol (betaxon™) and other β-adrenergic antagonists: Preclinical pharmacology, IOP-lowering activity and sites of action in human eyes
    • Sharif NA, Xu SX, Crider JY, McLaughlin M, Davis TL. Levobetaxolol (Betaxon™) and other b-adrenergic antagonists: preclinical pharmacology, IOP-lowering activity and sites of action in human eyes. J. Ocular Pharmacol. Ther. 17, 305-317 (2001). (Pubitemid 32888804)
    • (2001) Journal of Ocular Pharmacology and Therapeutics , vol.17 , Issue.4 , pp. 305-317
    • Sharif, N.A.1    Xu, S.X.2    Crider, J.Y.3    McLaughlin, M.4    Davis, T.L.5
  • 111
    • 12844283851 scopus 로고    scopus 로고
    • Effects of travoprost on aqueous humor dynamics in monkeys
    • DOI 10.1097/01.ijg.0000146361.15163.ea
    • Toris CB, Zhan GL, Camras CB, McLaughlin MA. Effects of travoprost on aqueous humor dynamics in monkeys. J. Glaucoma 14, 70-73 (2005). (Pubitemid 40165496)
    • (2005) Journal of Glaucoma , vol.14 , Issue.1 , pp. 70-73
    • Toris, C.B.1    Zhan, G.-L.2    Camras, C.B.3    McLaughlin, M.A.4
  • 112
    • 0242712187 scopus 로고    scopus 로고
    • 2A receptors: Increasing cGMP levels in rat frontal cortex
    • DOI 10.1016/S0028-3908(03)00287-9
    • Regina MJ, Winter JC, Rabin RA. Characterization of a novel effect of serotonin 5-HT1A and 5-HT2A receptors: increasing cGMP levels in rat frontal cortex. Neuropharmacology 45, 1041-1049 (2003). (Pubitemid 37412249)
    • (2003) Neuropharmacology , vol.45 , Issue.8 , pp. 1041-1049
    • Regina, M.J.1    Winter, J.C.2    Rabin, R.A.3
  • 113
    • 47249133883 scopus 로고    scopus 로고
    • NO-induced regulation of human trabecular meshwork cell volume and aqueous humor outflow facility involve the BKCa ion channel
    • Dismuke WM, Mbadugha CC, Ellis DZ. NO-induced regulation of human trabecular meshwork cell volume and aqueous humor outflow facility involve the BKCa ion channel. Am. J. Physiol. Cell Physiol. 294, C1378-C1386 (2008).
    • (2008) Am. J. Physiol. Cell Physiol. , vol.294
    • Dismuke, W.M.1    Mbadugha, C.C.2    Ellis, D.Z.3
  • 114
    • 67649992691 scopus 로고    scopus 로고
    • Human trabecular meshwork cell volume decrease by NO-independent soluble guanylate cyclase activators YC-1 and BAY-58-2667 involves the BKCa ion channel
    • Dismuke WM, Sharif NA, Ellis DZ. Human trabecular meshwork cell volume decrease by NO-independent soluble guanylate cyclase activators YC-1 and BAY-58-2667 involves the BKCa ion channel. Invest. Ophthalmol. Vis. Sci. 50, 3353-3359 (2009).
    • (2009) Invest. Ophthalmol. Vis. Sci. , vol.50 , pp. 3353-3359
    • Dismuke, W.M.1    Sharif, N.A.2    Ellis, D.Z.3
  • 117
    • 33646687247 scopus 로고    scopus 로고
    • Effects of a prostaglandin DP receptor agonist, AL-6598, on aqueous humor dynamics in a nonhuman primate model of glaucoma
    • DOI 10.1089/jop.2006.22.86
    • Toris CB, Zhan GL, Feilmeier MR, Camras CB, McLaughlin MA. Effects of a prostaglandin DP receptor agonist, AL-6598, on aqueous humor dynamics in a nonhuman primate model of glaucoma. J. Ocul. Pharmacol. Ther. 22, 86-92 (2006). (Pubitemid 43742944)
    • (2006) Journal of Ocular Pharmacology and Therapeutics , vol.22 , Issue.2 , pp. 86-92
    • Toris, C.B.1    Zhan, G.-L.2    Feilmeier, M.R.3    Camras, C.B.4    McLaughlin, M.A.5
  • 121
    • 0346887097 scopus 로고    scopus 로고
    • Contrast sensitivity improves after brimonidine therapy in primary open angle glaucoma: A case for neuroprotection
    • DOI 10.1136/bjo.87.12.1463
    • Evans DW, Hosking SL, Gherghel D, Bartlett JD. Contrast sensitivity improves after brimonidine therapy in primary open-angle glaucoma: a case for neuroprotection. Br. J. Ophthalmol. 87, 1463-1465 (2003). (Pubitemid 38010548)
    • (2003) British Journal of Ophthalmology , vol.87 , Issue.12 , pp. 1463-1465
    • Evans, D.W.1    Hosking, S.L.2    Gherghel, D.3    Bartlett, J.D.4
  • 122
    • 68149114500 scopus 로고    scopus 로고
    • Brinzolamide/ timolol: In open-angle glaucoma and ocular hypertension
    • Croxtall JD, Scott LJ. Brinzolamide/ timolol: in open-angle glaucoma and ocular hypertension. Drugs Aging 26, 437-446 (2009).
    • (2009) Drugs Aging , vol.26 , pp. 437-446
    • Croxtall, J.D.1    Scott, L.J.2
  • 123
    • 33745060439 scopus 로고    scopus 로고
    • Trabecular meshwork as a new target for the treatment of glaucoma
    • DOI 10.1358/dnp.2006.19.3.985929
    • Ferrer E. Trabecular meshwork as a new target for the treatment of glaucoma. Drug News Perspect. 19, 151-158 (2006). (Pubitemid 43886097)
    • (2006) Drug News and Perspectives , vol.19 , Issue.3 , pp. 151-158
    • Ferrer, E.1
  • 124
    • 77951025151 scopus 로고    scopus 로고
    • Strategies for optic nerve rescue and regeneration in glaucoma and optic neuropathies
    • Dalhmann-Noor AH, Vijay S, Strid Limb G, Khaw PT. Strategies for optic nerve rescue and regeneration in glaucoma and optic neuropathies. Drug Discov. Today 15, 287-299 (2010).
    • (2010) Drug Discov. Today , vol.15 , pp. 287-299
    • Dalhmann-Noor, A.H.1    Vijay, S.2    Strid Limb, G.3    Khaw, P.T.4
  • 125
    • 51749123987 scopus 로고    scopus 로고
    • Promoting optic nerve regeneration in adult mice with a pharmaceutical approach
    • Cho KS, Chen DF. Promoting optic nerve regeneration in adult mice with a pharmaceutical approach. Neurochem. Res. 33, 2126-2133 (2008).
    • (2008) Neurochem. Res. , vol.33 , pp. 2126-2133
    • Cho, K.S.1    Chen, D.F.2
  • 126
    • 49049120741 scopus 로고    scopus 로고
    • Engrafted chicken neural tube-derived stem cells support the innate propensity for axonal regeneration within the rat optic nerve
    • Charalambous P, Hurst LA, Thanos S. Engrafted chicken neural tube-derived stem cells support the innate propensity for axonal regeneration within the rat optic nerve. Invest. Ophthalmol. Vis. Sci. 49, 3513-3524 (2008).
    • (2008) Invest. Ophthalmol. Vis. Sci. , vol.49 , pp. 3513-3524
    • Charalambous, P.1    Hurst, L.A.2    Thanos, S.3
  • 127
    • 0030894739 scopus 로고    scopus 로고
    • In vivo and in vitro experiments show that betaxolol is a retinal neuroprotective agent
    • DOI 10.1016/S0006-8993(96)01393-5, PII S0006899396013935
    • Osborne NN, Cazevielle C, Carvalho AL et al. In vivo and in vitro experiments show that betaxolol is a retinal neuroprotective agent. Brain Res. 751, 113-123 (1997). (Pubitemid 27122142)
    • (1997) Brain Research , vol.751 , Issue.1 , pp. 113-123
    • Osborne, N.N.1    Cazevieille, C.2    Carvalho, A.L.3    Larsen, A.K.4    Desantis, L.5
  • 128
  • 130
    • 56449124760 scopus 로고    scopus 로고
    • How does lowering of intraocular pressure protect the optic nerve?
    • Mackenzie P, Cioffi G. How does lowering of intraocular pressure protect the optic nerve? Surv. Ophthalmol. 53(Suppl. 1), S39-S43 (2008).
    • (2008) Surv. Ophthalmol. , vol.53 , Issue.SUPPL. 1
    • MacKenzie, P.1    Cioffi, G.2
  • 131
    • 71149106854 scopus 로고    scopus 로고
    • SOCS3 deletion promotes optic nerve regeneration
    • Smith PD, Sun F, Park KK et al. SOCS3 deletion promotes optic nerve regeneration. Neuron 64, 617-623 (2009).
    • (2009) Neuron , vol.64 , pp. 617-623
    • Smith, P.D.1    Sun, F.2    Park, K.K.3
  • 134
    • 77952765906 scopus 로고    scopus 로고
    • Mitochondria: Their role in ganglion cell death and survival in primary open angle glaucoma
    • Osborne NN. Mitochondria: their role in ganglion cell death and survival in primary open angle glaucoma. Exp. Eye Res. 90, 750-757 (2010).
    • (2010) Exp. Eye Res. , vol.90 , pp. 750-757
    • Osborne, N.N.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.