Pharmacological characterisation of human 5-HT2 receptor subtypes

European Journal of Pharmacology

Volumn 414, Issue 1, 2001, Pages 23-30

  Jerman, Jeffrey C ^a   Brough, Stephen J ^a   Gager, Tracey ^a   Wood, Martyn ^a   Coldwell, Martyn C ^a   Smart, Darren ^a   Middlemiss, Derek N ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

Author keywords

5 HT2 receptor; Anxiety; Ca2+; Depression; FLIPR (fluorometric imaging plate reader); SH SY5Y; Sodium butyrate

Indexed keywords

1 (1 METHYL 5 INDOLYL) 3 (3 METHYL 5 ISOTHIAZOLYL)UREA; 1 [5 (2 THIENYLMETHOXY) 3 INDOLYL] 2 PROPANAMINE; 1 ISOPROPYL 6 METHYLERGOLINE 8 CARBOXYLIC ACID 2 HYDROXY 1 METHYLPROPYL ESTER; 1,2,3,5 TETRAHYDRO 5 METHYL 1 (3 PYRIDYLCARBAMOYL)PYRROLO[2,3 F]INDOLE; 5 METHOXY 3 (1,2,3,6 TETRAHYDRO 4 PYRIDYL) 1H INDOLE; 6 CHLORO 2 (1 PIPERAZINYL)PYRAZINE; 8 CHLORO 2,3,4,5 TETRAHYDRO 3 METHYL 5 PHENYL 1H 3 BENZAZEPIN 7 OL HYDROGEN MALEATE; RECEPTOR SUBTYPE; SEROTONIN 2 AGONIST; SEROTONIN 2 ANTAGONIST; SEROTONIN 2 RECEPTOR; UNCLASSIFIED DRUG;

ANXIETY NEUROSIS; ARTICLE; DEPRESSION; DRUG EFFICACY; DRUG POTENCY; HORMONE RECEPTOR INTERACTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION;

BUTYRATES; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; RECEPTOR, SEROTONIN, 5-HT2A; RECEPTOR, SEROTONIN, 5-HT2B; RECEPTOR, SEROTONIN, 5-HT2C; RECEPTORS, SEROTONIN; SEROTONIN AGONISTS; SEROTONIN ANTAGONISTS;

EID: 0035936837     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(01)00775-0     Document Type: Article

References (21)

1. 2C receptors
2. Butyrate rapidly induces growth inhibition and differentiation in HT-29 cells
3. 2B) in rat stomach fundus longitudinal muscle
4. 2 receptor subtypes: A family re-united
5. Signal transduction differences between 5-hydroxytryptamine type 2A and type 2C receptor systems
6. Effector pathway-dependent relative efficacy at serotonin type 2A and 2C receptors: Evidence for agonist-directed trafficking of receptor stimulus
7. 2C receptors
8. Non-linear regression using spreadsheets
9. A rapid and sensitive method for the quantitation of microgram quantities of protein utilising the principle of protein-dye binding
10. 50) of an enzymatic reaction
11. Induction of beta 2-adrenergic receptor mRNA and ligand binding in HeLa cells
12. 5-Hydroxytryptamine receptors and effector coupling mechanisms in peripheral tissues
13. International union of pharmacology classification of receptors for 5-hydroxtryptamine (serotonin)
14. Induction of catecholamine-responsive adenylate cyclase in HeLa cells by sodium butyrate. Evidence for a more efficient stimulatory regulatory component
15. Receptors for 5-hydroxytryptamine: Current perspectives on classification and nomenclature
16. 2C receptors expressed in the human neuroblastoma cell line SH-SY5Y: Comparative stimulation by hallucinogenic drugs
17. 2C receptors in CHO-K1 cells
18. i using the fluometric imaging plate reader (FLIPR)
19. 2B receptor-mediated calcium release from ryanodine-sensitive intracellular stores in human pulmonary artery endothelial cells
20. 2B receptor mediates contraction in the mesenteric artery of mineralocorticoid hypertensive rats
21. 2C receptors in functional studies