Broadening deoxysugar glycodiversity: Natural and engineered transaldolases unlock a complementary substrate space

Chemistry - A European Journal

Volumn 17, Issue 9, 2011, Pages 2623-2632

  Rale, Madhura ^a   Schneider, Sarah ^b   Sprenger, Georg A ^b   Samland, Anne K ^b   Fessner, Wolf Dieter ^a  

^a DARMSTADT UNIVERSITY OF TECHNOLOGY   (Germany)

^b UNIVERSITY OF STUTTGART   (Germany)

Author keywords

biocatalysis; carbohydrates; enzymes; protein engineering; stereoselectivity

Indexed keywords

ACTIVE SITE; ALDOLASES; ALIPHATIC ALDEHYDES; BINDING POCKETS; BIOCATALYSIS; BIOPROFILE; CARBOLIGATION; DEOXY SUGAR; DEOXYGENATIONS; DONOR SUBSTRATES; E. COLI; GLYCOSYLATED; MATRIX; PROPANONE; PROTECTIVE GROUP; PROTEIN ENGINEERING; REGIOCONTROL; STEREOSPECIFIC; SUBSTRATE BINDING; SUBSTRATE STRUCTURE; SUGAR MOIETY; SUPERIOR CATALYSTS; TRANSALDOLASE;

ACETONE; ALDEHYDES; BIOCHEMICAL ENGINEERING; CATALYSTS; ENZYMES; ESCHERICHIA COLI; GENETIC ENGINEERING; ORGANIC COMPOUNDS; STEREOSELECTIVITY; SUGARS;

SUBSTRATES;

BIOLOGICAL PRODUCT; CARBOHYDRATE; ESCHERICHIA COLI PROTEIN; FSAA PROTEIN, E COLI; LYASE; TRANSALDOLASE;

ARTICLE; CATALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; ENZYME SPECIFICITY; ENZYMOLOGY; ESCHERICHIA COLI; GENETICS; METABOLISM; PROTEIN ENGINEERING; STEREOISOMERISM; X RAY CRYSTALLOGRAPHY;

ALDEHYDE-LYASES; BIOLOGICAL PRODUCTS; CARBOHYDRATES; CATALYSIS; CRYSTALLOGRAPHY, X-RAY; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; MOLECULAR STRUCTURE; PROTEIN ENGINEERING; STEREOISOMERISM; SUBSTRATE SPECIFICITY; TRANSALDOLASE;

EID: 79951785412     PISSN: 09476539     EISSN: 15213765     Source Type: Journal    
DOI: 10.1002/chem.201002942     Document Type: Article

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