Structure of tagatose-1,6-bisphosphate aldolase. Insight into chiral discrimination, mechanism, and specificity of class II aldolases

Journal of Biological Chemistry

Volumn 277, Issue 24, 2002, Pages 22018-22024

  Hall, David R ^a,b,c,d   Bond, Charles S ^a,b,c,d   Leonard, Gordon A ^a,b,c,d   Ian Watt, C ^a,b,c,d   Berry, Alan ^a,b,c,d   Hunter, William N ^a,b,c,d  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

^b EUROPEAN SYNCHROTRON RADIATION FACILITY   (France)

^c UNIVERSITY OF MANCHESTER   (United Kingdom)

^d UNIVERSITY OF LEEDS   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALDEHYDES; CATALYSIS; CRYSTAL STRUCTURE; ESCHERICHIA COLI; HYDROGEN BONDS; POLYCONDENSATION; ZINC;

BIOTRANSFORMATION CHEMISTRY; CHIRAL DISCRIMINATION;

ENZYMES;

CATION; DIHYDROXYACETONE PHOSPHATE; FRUCTOSE BISPHOSPHATE ALDOLASE; GLYCERALDEHYDE 3 PHOSPHATE; HISTIDINE; PHOSPHOGLYCOLOHYDROXAMATE; TAGATOSE; TAGATOSE 1,6 DIPHOSPHATE ALDOLASE; TYROSINE; UNCLASSIFIED DRUG; ZINC ION;

ARTICLE; BIOTRANSFORMATION; CATALYSIS; CHIRALITY; CRYSTAL STRUCTURE; ENZYME MODIFICATION; ENZYME STRUCTURE; ESCHERICHIA COLI; HYDROGEN BOND; NONHUMAN; POLYMERIZATION; PRIORITY JOURNAL;

ALDEHYDE-LYASES; AMINO ACID SEQUENCE; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; ESCHERICHIA COLI; HEXOSES; MODELS, CHEMICAL; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN CONFORMATION; SUBSTRATE SPECIFICITY;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 0037077203     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M202464200     Document Type: Article

References (35)