Exploring substrate binding and discrimination in fructose 1,6- bisphosphate and tagatose 1,6-bisphosphate aldolases

European Journal of Biochemistry

Volumn 267, Issue 6, 2000, Pages 1858-1868

  Zgiby, Shaza M ^b   Thomson, Graeme J ^b   Qamar, Seema ^a,b   Berry, Alan ^b  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b UNIVERSITY OF LEEDS   (United Kingdom)

Author keywords

Aldolase; Fructose 1,6 bisphosphate; Protein engineering; Site directed mutagenesis; Tagatose 1,6 bisphosphate

Indexed keywords

FRUCTOSE BISPHOSPHATASE; FRUCTOSE BISPHOSPHATE ALDOLASE; GLYCERALDEHYDE 3 PHOSPHATE; TAGATOSE;

AMINO ACID SUBSTITUTION; ARTICLE; CATALYSIS; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME CONFORMATION; ENZYME KINETICS; ENZYME SPECIFICITY; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ALDEHYDE-LYASES; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; BACTERIAL PROTEINS; BINDING SITES; CATALYSIS; CLONING, MOLECULAR; CRYSTALLOGRAPHY, X-RAY; ENZYME INDUCTION; ESCHERICHIA COLI; FRUCTOSE-BISPHOSPHATE ALDOLASE; FRUCTOSEDIPHOSPHATES; HEXOSEDIPHOSPHATES; KINETICS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEIN BINDING; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; STEREOISOMERISM; SUBSTRATE SPECIFICITY;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; PHRAGMITES;

EID: 0000517820     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.2000.01191.x     Document Type: Article

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