-
1
-
-
48749089453
-
The adult human brain in preclinical drug development
-
1:CAS:528:DC%2BD1cXptFOqsLs%3D 18617887
-
M Dragunow 2008 The adult human brain in preclinical drug development Nat Rev Drug Discov 7 659 666 1:CAS:528:DC%2BD1cXptFOqsLs%3D 18617887
-
(2008)
Nat Rev Drug Discov
, vol.7
, pp. 659-666
-
-
Dragunow, M.1
-
3
-
-
38049187707
-
Reprogramming of human somatic cells to pluripotency with defined factors
-
1:CAS:528:DC%2BD1cXksVGhtQ%3D%3D 18157115
-
IH Park R Zhao JA West A Yabuuchi H Huo TA Ince PH Lerou MW Lensch GQ Daley 2008 Reprogramming of human somatic cells to pluripotency with defined factors Nature 451 141 146 1:CAS:528:DC%2BD1cXksVGhtQ%3D%3D 18157115
-
(2008)
Nature
, vol.451
, pp. 141-146
-
-
Park, I.H.1
Zhao, R.2
West, J.A.3
Yabuuchi, A.4
Huo, H.5
Ince, T.A.6
Lerou, P.H.7
Lensch, M.W.8
Daley, G.Q.9
-
4
-
-
36248966518
-
Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors
-
DOI 10.1016/j.cell.2007.11.019, PII S0092867407014717
-
K Takahashi K Tanabe M Ohnuki M Narita T Ichisaka K Tomoda S Yamanaka 2007 Induction of pluripotent stem cells from adult human fibroblasts by defined factors Cell 131 861 872 1:CAS:528:DC%2BD2sXhsVCntbbK 18035408 (Pubitemid 350138099)
-
(2007)
Cell
, vol.131
, Issue.5
, pp. 861-872
-
-
Takahashi, K.1
Tanabe, K.2
Ohnuki, M.3
Narita, M.4
Ichisaka, T.5
Tomoda, K.6
Yamanaka, S.7
-
5
-
-
84902086995
-
Neural differentiation of human embryonic stem cells
-
1:CAS:528:DC%2BD1cXjtVOntrc%3D 18369746
-
M Dottori MF Pera 2008 Neural differentiation of human embryonic stem cells Methods Mol Biol 438 19 30 1:CAS:528:DC%2BD1cXjtVOntrc%3D 18369746
-
(2008)
Methods Mol Biol
, vol.438
, pp. 19-30
-
-
Dottori, M.1
Pera, M.F.2
-
6
-
-
0345688742
-
Comparative Evaluation of Various Human Feeders for Prolonged Undifferentiated Growth of Human Embryonic Stem Cells
-
M Richards S Tan CY Fong A Biswas WK Chan A Bongso 2003 Comparative evaluation of various human feeders for prolonged undifferentiated growth of human embryonic stem cells Stem Cells 21 546 556 1:CAS:528:DC%2BD3sXnvFeisrY%3D 12968109 (Pubitemid 37444111)
-
(2003)
Stem Cells
, vol.21
, Issue.5
, pp. 546-556
-
-
Richards, M.1
Tan, S.2
Fong, C.-Y.3
Biswas, A.4
Chan, W.-K.5
Bongso, A.6
-
7
-
-
20144380595
-
Basic fibroblast growth factor supports undifferentiated human embryonic stem cell growth without conditioned medium
-
DOI 10.1634/stemcells.2004-0211
-
C Xu E Rosler J Jiang JS Lebkowski JD Gold C O'Sullivan K Delavan-Boorsma M Mok A Bronstein MK Carpenter 2005 Basic fibroblast growth factor supports undifferentiated human embryonic stem cell growth without conditioned medium Stem Cells 23 315 323 1:CAS:528:DC%2BD2MXjtFyjtb4%3D 15749926 (Pubitemid 40404450)
-
(2005)
Stem Cells
, vol.23
, Issue.3
, pp. 315-323
-
-
Xu, C.1
Rosler, E.2
Jiang, J.3
Lebkowski, J.S.4
Gold, J.D.5
O'Sullivan, C.6
Delavan-Boorsma, K.7
Mok, M.8
Bronstein, A.9
Carpenter, M.K.10
-
8
-
-
0034794417
-
Feeder-free growth of undifferentiated human embryonic stem cells
-
DOI 10.1038/nbt1001-971
-
C Xu MS Inokuma J Denham K Golds P Kundu JD Gold MK Carpenter 2001 Feeder-free growth of undifferentiated human embryonic stem cells Nat Biotechnol 19 971 974 1:CAS:528:DC%2BD3MXntl2msbY%3D 11581665 (Pubitemid 32947578)
-
(2001)
Nature Biotechnology
, vol.19
, Issue.10
, pp. 971-974
-
-
Xu, C.1
Inokuma, M.S.2
Denham, J.3
Golds, K.4
Kundu, P.5
Gold, J.D.6
Carpenter, M.K.7
-
9
-
-
18744401357
-
Human embryonic stem cells derived without feeder cells
-
DOI 10.1016/S0140-6736(05)66473-2, PII S0140673605664732
-
I Klimanskaya Y Chung L Meisner J Johnson MD West R Lanza 2005 Human embryonic stem cells derived without feeder cells Lancet 365 1636 1641 1:CAS:528:DC%2BD2MXktVGku7w%3D 15885296 (Pubitemid 40693413)
-
(2005)
Lancet
, vol.365
, Issue.9471
, pp. 1636-1641
-
-
Klimanskaya, I.1
Chung, Y.2
Meisner, L.3
Johnson, J.4
West, M.D.5
Lanza, R.6
-
10
-
-
0035991647
-
Preimplantation human embryos and embryonic stem cells show comparable expression of stage-specific embryonic antigens
-
JK Henderson JS Draper HS Baillie S Fishel JA Thomson H Moore PW Andrews 2002 Preimplantation human embryos and embryonic stem cells show comparable expression of stage-specific embryonic antigens Stem Cells 20 329 337 1:CAS:528:DC%2BD38Xmt1Siurk%3D 12110702 (Pubitemid 34765092)
-
(2002)
Stem Cells
, vol.20
, Issue.4
, pp. 329-337
-
-
Henderson, J.K.1
Draper, J.S.2
Baillie, H.S.3
Fishel, S.4
Thomson, J.A.5
Moore, H.6
Andrews, P.W.7
-
11
-
-
0034101804
-
Embryonic stem cell lines from human blastocysts: Somatic differentiation in vitro
-
DOI 10.1038/74447
-
BE Reubinoff MF Pera CY Fong A Trounson A Bongso 2000 Embryonic stem cell lines from human blastocysts: somatic differentiation in vitro Nat Biotechnol 18 399 404 1:CAS:528:DC%2BD3cXis1Gmt74%3D 10748519 (Pubitemid 30217526)
-
(2000)
Nature Biotechnology
, vol.18
, Issue.4
, pp. 399-404
-
-
Reubinoff, B.E.1
Pera, M.F.2
Fong, C.-Y.3
Trounson, A.4
Bongso, A.5
-
12
-
-
0141651622
-
Characterization and culture of human embryonic stem cells
-
DOI 10.1016/S1050-1738(03)00125-7, PII S1050173803001257
-
AL Laslett AA Filipczyk MF Pera 2003 Characterization and culture of human embryonic stem cells Trends Cardiovasc Med 13 295 301 1:CAS:528: DC%2BD3sXns12mtbo%3D 14522470 (Pubitemid 37159395)
-
(2003)
Trends in Cardiovascular Medicine
, vol.13
, Issue.7
, pp. 295-301
-
-
Laslett, A.L.1
Filipczyk, A.A.2
Pera, M.F.3
-
13
-
-
0038143611
-
Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells
-
DOI 10.1016/S0092-8674(03)00392-1
-
I Chambers D Colby M Robertson J Nichols S Lee S Tweedie A Smith 2003 Functional expression cloning of nanog, a pluripotency sustaining factor in embryonic stem cells Cell 113 643 655 1:CAS:528:DC%2BD3sXksFehur8%3D 12787505 (Pubitemid 36694189)
-
(2003)
Cell
, vol.113
, Issue.5
, pp. 643-655
-
-
Chambers, I.1
Colby, D.2
Robertson, M.3
Nichols, J.4
Lee, S.5
Tweedie, S.6
Smith, A.7
-
14
-
-
1442311693
-
Oct-4 Knockdown Induces Similar Patterns of Endoderm and Trophoblast Differentiation Markers in Human and Mouse Embryonic Stem Cells
-
DC Hay L Sutherland J Clark T Burdon 2004 Oct-4 knockdown induces similar patterns of endoderm and trophoblast differentiation markers in human and mouse embryonic stem cells Stem Cells 22 225 235 1:CAS:528:DC%2BD2cXis1Sgsbc%3D 14990861 (Pubitemid 38282637)
-
(2004)
Stem Cells
, vol.22
, Issue.2
, pp. 225-235
-
-
Hay, D.C.1
Sutherland, L.2
Clark, J.3
Burdon, T.4
-
15
-
-
15544388092
-
High-efficiency RNA interference in human embryonic stem cells
-
DOI 10.1634/stemcells.2004-0252
-
H Zaehres MW Lensch L Daheron SA Stewart J Itskovitz-Eldor GQ Daley 2005 High-efficiency RNA interference in human embryonic stem cells Stem Cells 23 299 305 1:CAS:528:DC%2BD2MXjtFyjtLY%3D 15749924 (Pubitemid 40404448)
-
(2005)
Stem Cells
, vol.23
, Issue.3
, pp. 299-305
-
-
Zaehres, H.1
Lensch, M.W.2
Daheron, L.3
Stewart, S.A.4
Itskovitz-Eldor, J.5
Daley, G.Q.6
-
16
-
-
0037806031
-
The homeoprotein nanog is required for maintenance of pluripotency in mouse epiblast and ES cells
-
DOI 10.1016/S0092-8674(03)00393-3
-
K Mitsui Y Tokuzawa H Itoh K Segawa M Murakami K Takahashi M Maruyama M Maeda S Yamanaka 2003 The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells Cell 113 631 642 1:CAS:528:DC%2BD3sXksFehur4%3D 12787504 (Pubitemid 36694188)
-
(2003)
Cell
, vol.113
, Issue.5
, pp. 631-642
-
-
Mitsui, K.1
Tokuzawa, Y.2
Itoh, H.3
Segawa, K.4
Murakami, M.5
Takahashi, K.6
Maruyama, M.7
Maeda, M.8
Yamanaka, S.9
-
17
-
-
25444435417
-
Downregulation of NANOG induces differentiation of human embryonic stem cells to extraembryonic lineages
-
DOI 10.1634/stemcells.2005-0080
-
L Hyslop M Stojkovic L Armstrong T Walter P Stojkovic S Przyborski M Herbert A Murdoch T Strachan M Lako 2005 Downregulation of NANOG induces differentiation of human embryonic stem cells to extraembryonic lineages Stem Cells 23 1035 1043 1:CAS:528:DC%2BD2MXhtFCks73F 15983365 (Pubitemid 41377718)
-
(2005)
Stem Cells
, vol.23
, Issue.8
, pp. 1035-1043
-
-
Hyslop, L.1
Stojkovic, M.2
Armstrong, L.3
Walter, T.4
Stojkovic, P.5
Przyborski, S.6
Herbert, M.7
Murdoch, A.8
Strachan, T.9
Lako, M.10
-
18
-
-
85099486245
-
Factors involved in self-renewal and pluripotency of embryonic stem cells
-
Darr H, Benvenisty N (2006) Factors involved in self-renewal and pluripotency of embryonic stem cells. Handb Exp Pharmacol: 1-19.
-
(2006)
Handb Exp Pharmacol
, pp. 1-19
-
-
Darr, H.1
Benvenisty, N.2
-
19
-
-
33748429062
-
Molecular control of pluripotency
-
DOI 10.1016/j.gde.2006.08.009, PII S0959437X06001602, Differentation and Gene Regulation
-
LA Boyer D Mathur R Jaenisch 2006 Molecular control of pluripotency Curr Opin Genet Dev 16 455 462 1:CAS:528:DC%2BD28Xps1Ogurg%3D 16920351 (Pubitemid 44345206)
-
(2006)
Current Opinion in Genetics and Development
, vol.16
, Issue.5
, pp. 455-462
-
-
Boyer, L.A.1
Mathur, D.2
Jaenisch, R.3
-
20
-
-
0032582513
-
Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4
-
DOI 10.1016/S0092-8674(00)81769-9
-
J Nichols B Zevnik K Anastassiadis H Niwa D Klewe-Nebenius I Chambers H Scholer A Smith 1998 Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor oct4 Cell 95 379 391 1:CAS:528:DyaK1cXntlCqt74%3D 9814708 (Pubitemid 28507326)
-
(1998)
Cell
, vol.95
, Issue.3
, pp. 379-391
-
-
Nichols, J.1
Zevnik, B.2
Anastassiadis, K.3
Niwa, H.4
Klewe-Nebenius, D.5
Chambers, I.6
Scholer, H.7
Smith, A.8
-
21
-
-
25144525014
-
Core transcriptional regulatory circuitry in human embryonic stem cells
-
DOI 10.1016/j.cell.2005.08.020, PII S0092867405008251
-
LA Boyer TI Lee MF Cole SE Johnstone SS Levine JP Zucker MG Guenther RM Kumar HL Murray RG Jenner DK Gifford DA Melton R Jaenisch RA Young 2005 Core transcriptional regulatory circuitry in human embryonic stem cells Cell 122 947 956 1:CAS:528:DC%2BD2MXhtVOrurbJ 16153702 (Pubitemid 41345211)
-
(2005)
Cell
, vol.122
, Issue.6
, pp. 947-956
-
-
Boyer, L.A.1
Tong, I.L.2
Cole, M.F.3
Johnstone, S.E.4
Levine, S.S.5
Zucker, J.P.6
Guenther, M.G.7
Kumar, R.M.8
Murray, H.L.9
Jenner, R.G.10
Gifford, D.K.11
Melton, D.A.12
Jaenisch, R.13
Young, R.A.14
-
22
-
-
14844359620
-
Octamer and sox elements are required for transcriptional cis regulation of Nanog gene expression
-
DOI 10.1128/MCB.25.6.2475-2485.2005
-
T Kuroda M Tada H Kubota H Kimura SY Hatano H Suemori N Nakatsuji T Tada 2005 Octamer and sox elements are required for transcriptional cis regulation of nanog gene expression Mol Cell Biol 25 2475 2485 1:CAS:528:DC%2BD2MXisVOiu7w%3D 15743839 (Pubitemid 40354640)
-
(2005)
Molecular and Cellular Biology
, vol.25
, Issue.6
, pp. 2475-2485
-
-
Kuroda, T.1
Tada, M.2
Kubota, H.3
Kimura, H.4
Hatano, S.-Y.5
Suemori, H.6
Nakatsuji, N.7
Tada, T.8
-
23
-
-
21644434480
-
Transcriptional regulation of Nanog by OCT4 and SOX2
-
DOI 10.1074/jbc.M502573200
-
DJ Rodda JL Chew LH Lim YH Loh B Wang HH Ng P Robson 2005 Transcriptional regulation of nanog by oct4 and sox2 J Biol Chem 280 24731 24737 1:CAS:528:DC%2BD2MXlsFyqs78%3D 15860457 (Pubitemid 40934562)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.26
, pp. 24731-24737
-
-
Rodda, D.J.1
Chew, J.-L.2
Lim, L.-H.3
Loh, Y.-H.4
Wang, B.5
Ng, H.-H.6
Robson, P.7
-
24
-
-
41349090105
-
Generation of human induced pluripotent stem cells from dermal fibroblasts
-
DOI 10.1073/pnas.0711983105
-
WE Lowry L Richter R Yachechko AD Pyle J Tchieu R Sridharan AT Clark K Plath 2008 Generation of human induced pluripotent stem cells from dermal fibroblasts Proc Natl Acad Sci USA 105 2883 2888 1:CAS:528:DC%2BD1cXjtVSisr0%3D 18287077 (Pubitemid 351723638)
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.8
, pp. 2883-2888
-
-
Lowry, W.E.1
Richter, L.2
Yachechko, R.3
Pyle, A.D.4
Tchieu, J.5
Sridharan, R.6
Clark, A.T.7
Plath, K.8
-
25
-
-
38049028459
-
Generation of induced pluripotent stem cells without myc from mouse and human fibroblasts
-
1:CAS:528:DC%2BD1cXisFGmuw%3D%3D 18059259
-
M Nakagawa M Koyanagi K Tanabe K Takahashi T Ichisaka T Aoi K Okita Y Mochiduki N Takizawa S Yamanaka 2008 Generation of induced pluripotent stem cells without myc from mouse and human fibroblasts Nat Biotechnol 26 101 106 1:CAS:528:DC%2BD1cXisFGmuw%3D%3D 18059259
-
(2008)
Nat Biotechnol
, vol.26
, pp. 101-106
-
-
Nakagawa, M.1
Koyanagi, M.2
Tanabe, K.3
Takahashi, K.4
Ichisaka, T.5
Aoi, T.6
Okita, K.7
Mochiduki, Y.8
Takizawa, N.9
Yamanaka, S.10
-
26
-
-
34548445454
-
Generation of Induced Pluripotent Stem Cells in the Absence of Drug Selection
-
DOI 10.1016/j.stem.2007.08.008, PII S1934590907001270
-
R Blelloch M Venere J Yen M Ramalho-Santos 2007 Generation of induced pluripotent stem cells in the absence of drug selection Cell Stem Cell 1 245 247 1:CAS:528:DC%2BD2sXhtFagu7rN 18371358 (Pubitemid 47355331)
-
(2007)
Cell Stem Cell
, vol.1
, Issue.3
, pp. 245-247
-
-
Blelloch, R.1
Venere, M.2
Yen, J.3
Ramalho-Santos, M.4
-
27
-
-
55749104227
-
Induction of pluripotent stem cells from primary human fibroblasts with only oct4 and sox2
-
1:CAS:528:DC%2BD1cXhtlCktrvE 18849973
-
D Huangfu K Osafune R Maehr W Guo A Eijkelenboom S Chen W Muhlestein DA Melton 2008 Induction of pluripotent stem cells from primary human fibroblasts with only oct4 and sox2 Nat Biotechnol 26 1269 1275 1:CAS:528:DC%2BD1cXhtlCktrvE 18849973
-
(2008)
Nat Biotechnol
, vol.26
, pp. 1269-1275
-
-
Huangfu, D.1
Osafune, K.2
Maehr, R.3
Guo, W.4
Eijkelenboom, A.5
Chen, S.6
Muhlestein, W.7
Melton, D.A.8
-
28
-
-
60649084367
-
Induced pluripotent stem cells: Current progress and potential for regenerative medicine
-
1:CAS:528:DC%2BD1MXhvF2mur4%3D 19162546
-
G Amabile A Meissner 2009 Induced pluripotent stem cells: current progress and potential for regenerative medicine Trends Mol Med 15 59 68 1:CAS:528:DC%2BD1MXhvF2mur4%3D 19162546
-
(2009)
Trends Mol Med
, vol.15
, pp. 59-68
-
-
Amabile, G.1
Meissner, A.2
-
29
-
-
36749043230
-
Induced pluripotent stem cell lines derived from human somatic cells
-
1:CAS:528:DC%2BD2sXhsVGjsLbN 18029452
-
J Yu MA Vodyanik K Smuga-Otto J Antosiewicz-Bourget JL Frane S Tian J Nie GA Jonsdottir V Ruotti R Stewart II Slukvin JA Thomson 2007 Induced pluripotent stem cell lines derived from human somatic cells Science 318 1917 1920 1:CAS:528:DC%2BD2sXhsVGjsLbN 18029452
-
(2007)
Science
, vol.318
, pp. 1917-1920
-
-
Yu, J.1
Vodyanik, M.A.2
Smuga-Otto, K.3
Antosiewicz-Bourget, J.4
Frane, J.L.5
Tian, S.6
Nie, J.7
Jonsdottir, G.A.8
Ruotti, V.9
Stewart, R.10
Slukvin, I.I.11
Thomson, J.A.12
-
31
-
-
75349088911
-
The nuclear receptor nr5a2 can replace oct4 in the reprogramming of murine somatic cells to pluripotent cells
-
Heng JC, Feng B, Han J, Jiang J, Kraus P, Ng JH, Orlov YL, Huss M, Yang L, Lufkin T, Lim B, Ng HH (2010) The nuclear receptor nr5a2 can replace oct4 in the reprogramming of murine somatic cells to pluripotent cells. Cell Stem Cell 6:167-174
-
(2010)
Cell Stem Cell
, vol.6
, pp. 167-174
-
-
Heng, J.C.1
Feng, B.2
Han, J.3
Jiang, J.4
Kraus, P.5
Ng, J.H.6
Orlov, Y.L.7
Huss, M.8
Yang, L.9
Lufkin, T.10
Lim, B.11
Ng, H.H.12
-
32
-
-
46949085597
-
Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds
-
DOI 10.1038/nbt1418, PII NBT1418
-
D Huangfu R Maehr W Guo A Eijkelenboom M Snitow AE Chen DA Melton 2008 Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds Nat Biotechnol 26 795 797 1:CAS:528: DC%2BD1cXot1entL0%3D 18568017 (Pubitemid 351961456)
-
(2008)
Nature Biotechnology
, vol.26
, Issue.7
, pp. 795-797
-
-
Huangfu, D.1
Maehr, R.2
Guo, W.3
Eijkelenboom, A.4
Snitow, M.5
Chen, A.E.6
Melton, D.A.7
-
33
-
-
46449094276
-
Dissecting direct reprogramming through integrative genomic analysis
-
DOI 10.1038/nature07056, PII NATURE07056
-
TS Mikkelsen J Hanna X Zhang M Ku M Wernig P Schorderet BE Bernstein R Jaenisch ES Lander A Meissner 2008 Dissecting direct reprogramming through integrative genomic analysis Nature 454 49 55 1:CAS:528:DC%2BD1cXotVertb4%3D 18509334 (Pubitemid 351931978)
-
(2008)
Nature
, vol.454
, Issue.7200
, pp. 49-55
-
-
Mikkelsen, T.S.1
Hanna, J.2
Zhang, X.3
Ku, M.4
Wernig, M.5
Schorderet, P.6
Bernstein, B.E.7
Jaenisch, R.8
Lander, E.S.9
Meissner, A.10
-
34
-
-
70350732790
-
A chemical platform for improved induction of human iPSCs
-
1:CAS:528:DC%2BD1MXht1OgsrzE 19838168
-
T Lin R Ambasudhan X Yuan W Li S Hilcove R Abujarour X Lin HS Hahm E Hao A Hayek S Ding 2009 A chemical platform for improved induction of human iPSCs Nat Methods 6 805 808 1:CAS:528:DC%2BD1MXht1OgsrzE 19838168
-
(2009)
Nat Methods
, vol.6
, pp. 805-808
-
-
Lin, T.1
Ambasudhan, R.2
Yuan, X.3
Li, W.4
Hilcove, S.5
Abujarour, R.6
Lin, X.7
Hahm, H.S.8
Hao, E.9
Hayek, A.10
Ding, S.11
-
35
-
-
0032491416
-
Embryonic stem cell lines derived from human blastocysts
-
JA Thomson J Itskovitz-Eldor SS Shapiro MA Waknitz JJ Swiergiel VS Marshall JM Jones 1998 Embryonic stem cell lines derived from human blastocysts Science 282 1145 1147 1:CAS:528:DyaK1cXntleisLg%3D 9804556 (Pubitemid 28516247)
-
(1998)
Science
, vol.282
, Issue.5391
, pp. 1145-1147
-
-
Thomson, J.A.1
-
36
-
-
0036714330
-
Human feeders support prolonged undifferentiated growth of human inner cell masses and embryonic stem cells
-
DOI 10.1038/nbt726
-
M Richards CY Fong WK Chan PC Wong A Bongso 2002 Human feeders support prolonged undifferentiated growth of human inner cell masses and embryonic stem cells Nat Biotechnol 20 933 936 1:CAS:528:DC%2BD38Xms1ahsL8%3D 12161760 (Pubitemid 35001132)
-
(2002)
Nature Biotechnology
, vol.20
, Issue.9
, pp. 933-936
-
-
Richards, M.1
Fong, C.-Y.2
Chan, W.-K.3
Wong, P.-C.4
Bongso, A.5
-
37
-
-
0038724202
-
Human feeder layers for human embryonic stem cells
-
DOI 10.1095/biolreprod.102.012583
-
M Amit V Margulets H Segev K Shariki I Laevsky R Coleman J Itskovitz-Eldor 2003 Human feeder layers for human embryonic stem cells Biol Reprod 68 2150 2156 1:CAS:528:DC%2BD3sXks1Ggsb8%3D 12606388 (Pubitemid 36687007)
-
(2003)
Biology of Reproduction
, vol.68
, Issue.6
, pp. 2150-2156
-
-
Amit, M.1
Margulets, V.2
Segev, H.3
Shariki, K.4
Laevsky, I.5
Coleman, R.6
Itskovitz-Eldor, J.7
-
38
-
-
22244450014
-
Large-scale propagation of four undifferentiated human embryonic stem cell lines in a feeder-free culture system
-
DOI 10.1002/dvdy.20459
-
E Sjogren-Jansson M Zetterstrom K Moya J Lindqvist R Strehl PS Eriksson 2005 Large-scale propagation of four undifferentiated human embryonic stem cell lines in a feeder-free culture system Dev Dyn 233 1304 1314 15965986 (Pubitemid 40995128)
-
(2005)
Developmental Dynamics
, vol.233
, Issue.4
, pp. 1304-1314
-
-
Sjogren-Jansson, E.1
Zetterstrom, M.2
Moya, K.3
Lindqvist, J.4
Strehl, R.5
Eriksson, P.S.6
-
39
-
-
33646474117
-
Long-term self-renewal and directed differentiation of human embryonic stem cells in chemically defined conditions
-
1:CAS:528:DC%2BD28XkslCksLg%3D 16632596
-
S Yao S Chen J Clark E Hao GM Beattie A Hayek S Ding 2006 Long-term self-renewal and directed differentiation of human embryonic stem cells in chemically defined conditions Proc Natl Acad Sci USA 103 6907 6912 1:CAS:528:DC%2BD28XkslCksLg%3D 16632596
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 6907-6912
-
-
Yao, S.1
Chen, S.2
Clark, J.3
Hao, E.4
Beattie, G.M.5
Hayek, A.6
Ding, S.7
-
40
-
-
23844444042
-
Characterization and culture of human embryonic stem cells
-
DOI 10.1038/nbt1102
-
LM Hoffman MK Carpenter 2005 Characterization and culture of human embryonic stem cells Nat Biotechnol 23 699 708 1:CAS:528:DC%2BD2MXkvVShs7o%3D 15940242 (Pubitemid 41716360)
-
(2005)
Nature Biotechnology
, vol.23
, Issue.6
, pp. 699-708
-
-
Hoffman, L.M.1
Carpenter, M.K.2
-
41
-
-
46749118841
-
Use of xenofree matrices and molecularly-defined media to control human embryonic stem cell pluripotency: Effect of low physiological TGF-β concentrations
-
DOI 10.1089/scd.2007.0279
-
I Peiffer R Barbet YP Zhou ML Li MN Monier A Hatzfeld JA Hatzfeld 2008 Use of xenofree matrices and molecularly-defined media to control human embryonic stem cell pluripotency: effect of low physiological TGF-beta concentrations Stem Cells Dev 17 519 533 1:CAS:528:DC%2BD1cXnslKktrY%3D 18513159 (Pubitemid 351948204)
-
(2008)
Stem Cells and Development
, vol.17
, Issue.3
, pp. 519-533
-
-
Peiffer, I.1
Barbet, R.2
Zhou, Y.-P.3
Li, M.-L.4
Monier, M.-N.5
Hatzfeld, A.6
Hatzfeld, J.A.7
-
42
-
-
32344438401
-
Derivation of human embryonic stem cells in defined conditions
-
DOI 10.1038/nbt1177, PII NBT1177
-
TE Ludwig ME Levenstein JM Jones WT Berggren ER Mitchen JL Frane LJ Crandall CA Daigh KR Conard MS Piekarczyk RA Llanas JA Thomson 2006 Derivation of human embryonic stem cells in defined conditions Nat Biotechnol 24 185 187 1:CAS:528:DC%2BD28XhtFGqsrg%3D 16388305 (Pubitemid 43221701)
-
(2006)
Nature Biotechnology
, vol.24
, Issue.2
, pp. 185-187
-
-
Ludwig, T.E.1
Levenstein, M.E.2
Jones, J.M.3
Berggren, W.T.4
Mitchen, E.R.5
Frane, J.L.6
Crandall, L.J.7
Daigh, C.A.8
Conard, K.R.9
Piekarczyk, M.S.10
Llanas, R.A.11
Thomson, J.A.12
-
43
-
-
16444373230
-
Activin A maintains pluripotency of human embryonic stem cells in the absence of feeder layers
-
DOI 10.1634/stemcells.2004-0279
-
GM Beattie AD Lopez N Bucay A Hinton MT Firpo CC King A Hayek 2005 Activin a maintains pluripotency of human embryonic stem cells in the absence of feeder layers Stem Cells 23 489 495 1:CAS:528:DC%2BD2MXjslGjsrY%3D 15790770 (Pubitemid 40478488)
-
(2005)
Stem Cells
, vol.23
, Issue.4
, pp. 489-495
-
-
Beattie, G.M.1
Lopez, A.D.2
Bucay, N.3
Hinton, A.4
Firpo, M.T.5
King, C.C.6
Hayek, A.7
-
44
-
-
51649093059
-
Heparin promotes the growth of human embryonic stem cells in a defined serum-free medium
-
1:CAS:528:DC%2BD1cXhtFChs7rM 18725626
-
MK Furue J Na JP Jackson T Okamoto M Jones D Baker R Hata HD Moore JD Sato PW Andrews 2008 Heparin promotes the growth of human embryonic stem cells in a defined serum-free medium Proc Natl Acad Sci USA 105 13409 13414 1:CAS:528:DC%2BD1cXhtFChs7rM 18725626
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 13409-13414
-
-
Furue, M.K.1
Na, J.2
Jackson, J.P.3
Okamoto, T.4
Jones, M.5
Baker, D.6
Hata, R.7
Moore, H.D.8
Sato, J.D.9
Andrews, P.W.10
-
45
-
-
1242276404
-
Feeder Layer- and Serum-Free Culture of Human Embryonic Stem Cells
-
DOI 10.1095/biolreprod.103.021147
-
M Amit C Shariki V Margulets J Itskovitz-Eldor 2004 Feeder layer- and serum-free culture of human embryonic stem cells Biol Reprod 70 837 845 1:CAS:528:DC%2BD2cXhs1Chtr8%3D 14627547 (Pubitemid 38233724)
-
(2004)
Biology of Reproduction
, vol.70
, Issue.3
, pp. 837-845
-
-
Amit, M.1
Shariki, C.2
Margulets, V.3
Itskovitz-Eldor, J.4
-
46
-
-
67650659087
-
Comparison of biomaterials and extracellular matrices as a culture platform for multiple, independently derived human embryonic stem cell lines
-
1:CAS:528:DC%2BD1MXos1Wjsrk%3D 19132919
-
H Hakala K Rajala M Ojala S Panula S Areva M Kellomaki R Suuronen H Skottman 2009 Comparison of biomaterials and extracellular matrices as a culture platform for multiple, independently derived human embryonic stem cell lines Tissue Eng Part A 15 1775 1785 1:CAS:528:DC%2BD1MXos1Wjsrk%3D 19132919
-
(2009)
Tissue Eng Part A
, vol.15
, pp. 1775-1785
-
-
Hakala, H.1
Rajala, K.2
Ojala, M.3
Panula, S.4
Areva, S.5
Kellomaki, M.6
Suuronen, R.7
Skottman, H.8
-
49
-
-
48349108772
-
The benefit of human embryonic stem cell encapsulation for prolonged feeder-free maintenance
-
1:CAS:528:DC%2BD1cXps1Srt74%3D 18639332
-
N Siti-Ismail AE Bishop JM Polak A Mantalaris 2008 The benefit of human embryonic stem cell encapsulation for prolonged feeder-free maintenance Biomaterials 29 3946 3952 1:CAS:528:DC%2BD1cXps1Srt74%3D 18639332
-
(2008)
Biomaterials
, vol.29
, pp. 3946-3952
-
-
Siti-Ismail, N.1
Bishop, A.E.2
Polak, J.M.3
Mantalaris, A.4
-
50
-
-
0034669082
-
Clonally derived human embryonic stem cell lines maintain pluripotency and proliferative potential for prolonged periods of culture
-
1:CAS:528:DC%2BD3cXnvVeks70%3D 11071754
-
M Amit MK Carpenter MS Inokuma CP Chiu CP Harris MA Waknitz J Itskovitz-Eldor JA Thomson 2000 Clonally derived human embryonic stem cell lines maintain pluripotency and proliferative potential for prolonged periods of culture Dev Biol 227 271 278 1:CAS:528:DC%2BD3cXnvVeks70%3D 11071754
-
(2000)
Dev Biol
, vol.227
, pp. 271-278
-
-
Amit, M.1
Carpenter, M.K.2
Inokuma, M.S.3
Chiu, C.P.4
Harris, C.P.5
Waknitz, M.A.6
Itskovitz-Eldor, J.7
Thomson, J.A.8
-
51
-
-
0041560908
-
Molecular signature of human embryonic stem cells and its comparison with the mouse
-
DOI 10.1016/S0012-1606(03)00256-2
-
N Sato IM Sanjuan M Heke M Uchida F Naef AH Brivanlou 2003 Molecular signature of human embryonic stem cells and its comparison with the mouse Dev Biol 260 404 413 1:CAS:528:DC%2BD3sXmt1WqtL0%3D 12921741 (Pubitemid 36960088)
-
(2003)
Developmental Biology
, vol.260
, Issue.2
, pp. 404-413
-
-
Sato, N.1
Munoz Sanjuan, I.2
Heke, M.3
Uchida, M.4
Naef, F.5
Brivanlou, A.H.6
-
52
-
-
28444438841
-
Defining the role of Wnt/β-catenin signaling in the survival, proliferation, and self-renewal of human embryonic stem cells
-
DOI 10.1634/stemcells.2005-0034
-
G Dravid Z Ye H Hammond G Chen A Pyle P Donovan X Yu L Cheng 2005 Defining the role of wnt/beta-catenin signaling in the survival, proliferation, and self-renewal of human embryonic stem cells Stem Cells 23 1489 1501 1:CAS:528:DC%2BD28Xmtw%3D%3D 16002782 (Pubitemid 41740998)
-
(2005)
Stem Cells
, vol.23
, Issue.10
, pp. 1489-1501
-
-
Dravid, G.1
Ye, Z.2
Hammond, H.3
Chen, G.4
Pyle, A.5
Donovan, P.6
Yu, X.7
Cheng, L.8
-
53
-
-
1242267927
-
Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor
-
DOI 10.1038/nm979
-
N Sato L Meijer L Skaltsounis P Greengard AH Brivanlou 2004 Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor Nat Med 10 55 63 1:CAS:528:DC%2BD2cXlsFGm 14702635 (Pubitemid 38524699)
-
(2004)
Nature Medicine
, vol.10
, Issue.1
, pp. 55-63
-
-
Sato, N.1
Meijer, L.2
Skaltsounis, L.3
Greengard, P.4
Brivanlou, A.H.5
-
54
-
-
33846251988
-
Promoting human embryonic stem cell renewal or differentiation by modulating Wnt signal and culture conditions
-
DOI 10.1038/sj.cr.7310138, PII 7310138
-
L Cai Z Ye BY Zhou P Mali C Zhou L Cheng 2007 Promoting human embryonic stem cell renewal or differentiation by modulating Wnt signal and culture conditions Cell Res 17 62 72 1:CAS:528:DC%2BD2sXksleqsQ%3D%3D 17211448 (Pubitemid 46096426)
-
(2007)
Cell Research
, vol.17
, Issue.1
, pp. 62-72
-
-
Cai, L.1
Ye, Z.2
Zhou, B.Y.3
Mali, P.4
Zhou, C.5
Cheng, L.6
-
55
-
-
53349091628
-
Defining early lineage specification of human embryonic stem cells by the orchestrated balance of canonical Wnt/beta-catenin, Activin/Nodal and BMP signaling
-
1:CAS:528:DC%2BD1cXht1Sns7fN 18667462
-
T Sumi N Tsuneyoshi N Nakatsuji H Suemori 2008 Defining early lineage specification of human embryonic stem cells by the orchestrated balance of canonical Wnt/beta-catenin, Activin/Nodal and BMP signaling Development 135 2969 2979 1:CAS:528:DC%2BD1cXht1Sns7fN 18667462
-
(2008)
Development
, vol.135
, pp. 2969-2979
-
-
Sumi, T.1
Tsuneyoshi, N.2
Nakatsuji, N.3
Suemori, H.4
-
56
-
-
7744241519
-
Wnt signaling and the regulation of stem cell function
-
DOI 10.1016/j.ceb.2004.08.006, PII S095506740400119X
-
M Kleber L Sommer 2004 Wnt signaling and the regulation of stem cell function Curr Opin Cell Biol 16 681 687 1:CAS:528:DC%2BD2cXpsVOrur4%3D 15530781 (Pubitemid 39463120)
-
(2004)
Current Opinion in Cell Biology
, vol.16
, Issue.6
, pp. 681-687
-
-
Kleber, M.1
Sommer, L.2
-
57
-
-
33846931113
-
Fibroblast growth factor 2 modulates transforming growth factor β signaling in mouse embryonic fibroblasts and human ESCs (hESCs) to support hESC self-renewal
-
DOI 10.1634/stemcells.2006-0476
-
B Greber H Lehrach J Adjaye 2007 Fibroblast growth factor 2 modulates transforming growth factor beta signaling in mouse embryonic fibroblasts and human ESCs (hESCs) to support hESC self-renewal Stem Cells 25 455 464 1:CAS:528:DC%2BD2sXivVOlt7g%3D 17038665 (Pubitemid 46232801)
-
(2007)
Stem Cells
, vol.25
, Issue.2
, pp. 455-464
-
-
Greber, B.1
Lehrach, H.2
Adjaye, J.3
-
58
-
-
25444503012
-
Expression and potential role of fibroblast growth factor 2 and its receptors in human embryonic stem cells
-
DOI 10.1634/stemcells.2004-0303
-
P Dvorak D Dvorakova S Koskova M Vodinska M Najvirtova D Krekac A Hampl 2005 Expression and potential role of fibroblast growth factor 2 and its receptors in human embryonic stem cells Stem Cells 23 1200 1211 1:CAS:528:DC%2BD2MXhtFCks7jF 15955829 (Pubitemid 41377735)
-
(2005)
Stem Cells
, vol.23
, Issue.8
, pp. 1200-1211
-
-
Dvorak, P.1
Dvorakova, D.2
Koskova, S.3
Vodinska, M.4
Najvirtova, M.5
Krekac, D.6
Hampl, A.7
-
59
-
-
33947233409
-
MEK/ERK signaling contributes to the maintenance of human embryonic stem cell self-renewal
-
DOI 10.1111/j.1432-0436.2006.00143.x
-
J Li G Wang C Wang Y Zhao H Zhang Z Tan Z Song M Ding H Deng 2007 Mek/erk signaling contributes to the maintenance of human embryonic stem cell self-renewal Differentiation 75 299 307 1:CAS:528:DC%2BD2sXktVOjsLg%3D 17286604 (Pubitemid 46434953)
-
(2007)
Differentiation
, vol.75
, Issue.4
, pp. 299-307
-
-
Li, J.1
Wang, G.2
Wang, C.3
Zhao, Y.4
Zhang, H.5
Tan, Z.6
Song, Z.7
Ding, M.8
Deng, H.9
-
60
-
-
69249098573
-
A complex role for FGF-2 in self-renewal, survival, and adhesion of human embryonic stem cells
-
1:CAS:528:DC%2BD1MXht1ajsr%2FO 19544431
-
L Eiselleova K Matulka V Kriz M Kunova Z Schmidtova J Neradil B Tichy D Dvorakova S Pospisilova A Hampl P Dvorak 2009 A complex role for FGF-2 in self-renewal, survival, and adhesion of human embryonic stem cells Stem Cells 27 1847 1857 1:CAS:528:DC%2BD1MXht1ajsr%2FO 19544431
-
(2009)
Stem Cells
, vol.27
, pp. 1847-1857
-
-
Eiselleova, L.1
Matulka, K.2
Kriz, V.3
Kunova, M.4
Schmidtova, Z.5
Neradil, J.6
Tichy, B.7
Dvorakova, D.8
Pospisilova, S.9
Hampl, A.10
Dvorak, P.11
-
61
-
-
18744375483
-
Basic FGF and suppression of BMP signaling sustain undifferentiated proliferation of human ES cells
-
DOI 10.1038/nmeth744
-
RH Xu RM Peck DS Li X Feng T Ludwig JA Thomson 2005 Basic FGF and suppression of BMP signaling sustain undifferentiated proliferation of human ES cells Nat Methods 2 185 190 1:CAS:528:DC%2BD2MXisVGisrc%3D 15782187 (Pubitemid 41122125)
-
(2005)
Nature Methods
, vol.2
, Issue.3
, pp. 185-190
-
-
Xu, R.-H.1
Peck, R.M.2
Li, D.S.3
Feng, X.4
Ludwig, T.5
Thomson, J.A.6
-
62
-
-
33747614295
-
Activin A maintains self-renewal and regulates fibroblast growth factor, Wnt, and bone morphogenic protein pathways in human embryonic stem cells
-
DOI 10.1634/stemcells.2005-0299
-
L Xiao X Yuan SJ Sharkis 2006 Activin A maintains self-renewal and regulates fibroblast growth factor, wnt, and bone morphogenic protein pathways in human embryonic stem cells Stem Cells 24 1476 1486 1:CAS:528: DC%2BD28XhtFKlsbbM 16456129 (Pubitemid 44464664)
-
(2006)
Stem Cells
, vol.24
, Issue.6
, pp. 1476-1486
-
-
Xiao, L.1
Yuan, X.2
Sharkis, S.J.3
-
63
-
-
16244400050
-
TGFβ/activin/nodal signaling is necessary for the maintenance of pluripotency in human embryonic stem cells
-
DOI 10.1242/dev.01706
-
D James AJ Levine D Besser A Hemmati-Brivanlou 2005 TGFbeta/activin/nodal signaling is necessary for the maintenance of pluripotency in human embryonic stem cells Development 132 1273 1282 1:CAS:528:DC%2BD2MXjsFentLs%3D 15703277 (Pubitemid 40528787)
-
(2005)
Development
, vol.132
, Issue.6
, pp. 1273-1282
-
-
James, D.1
Levine, A.J.2
Besser, D.3
Hemmati-Brivanlou, A.4
-
64
-
-
20144389935
-
Noggin and bFGF cooperate to maintain the pluripotency of human embryonic stem cells in the absence of feeder layers
-
DOI 10.1016/j.bbrc.2005.03.058
-
G Wang H Zhang Y Zhao J Li J Cai P Wang S Meng J Feng C Miao M Ding D Li H Deng 2005 Noggin and bFGF cooperate to maintain the pluripotency of human embryonic stem cells in the absence of feeder layers Biochem Biophys Res Commun 330 934 942 1:CAS:528:DC%2BD2MXivV2jurg%3D 15809086 (Pubitemid 40462176)
-
(2005)
Biochemical and Biophysical Research Communications
, vol.330
, Issue.3
, pp. 934-942
-
-
Wang, G.1
Zhang, H.2
Zhao, Y.3
Li, J.4
Cai, J.5
Wang, P.6
Meng, S.7
Feng, J.8
Miao, C.9
Ding, M.10
Li, D.11
Deng, H.12
-
65
-
-
48149098004
-
Nanog is a direct target of TGFbeta/activin-mediated smad signaling in human ESCs
-
1:CAS:528:DC%2BD1cXhtVegtr%2FO 18682241
-
RH Xu TL Sampsell-Barron F Gu S Root RM Peck G Pan J Yu J Antosiewicz-Bourget S Tian R Stewart JA Thomson 2008 Nanog is a direct target of TGFbeta/activin-mediated smad signaling in human ESCs Cell Stem Cell 3 196 206 1:CAS:528:DC%2BD1cXhtVegtr%2FO 18682241
-
(2008)
Cell Stem Cell
, vol.3
, pp. 196-206
-
-
Xu, R.H.1
Sampsell-Barron, T.L.2
Gu, F.3
Root, S.4
Peck, R.M.5
Pan, G.6
Yu, J.7
Antosiewicz-Bourget, J.8
Tian, S.9
Stewart, R.10
Thomson, J.A.11
-
66
-
-
27644486756
-
Activin/Nodal and FGF pathways cooperate to maintain pluripotency of human embryonic stem cells
-
DOI 10.1242/jcs.02553
-
L Vallier M Alexander RA Pedersen 2005 Activin/nodal and FGF pathways cooperate to maintain pluripotency of human embryonic stem cells J Cell Sci 118 4495 4509 1:CAS:528:DC%2BD2MXht1WnurrP 16179608 (Pubitemid 41556347)
-
(2005)
Journal of Cell Science
, vol.118
, Issue.19
, pp. 4495-4509
-
-
Vallier, L.1
Alexander, M.2
Pedersen, R.A.3
-
67
-
-
34548307176
-
IGF and FGF cooperatively establish the regulatory stem cell niche of pluripotent human cells in vitro
-
DOI 10.1038/nature06027, PII NATURE06027
-
SC Bendall MH Stewart P Menendez D George K Vijayaragavan T Werbowetski-Ogilvie V Ramos-Mejia A Rouleau J Yang M Bosse G Lajoie M Bhatia 2007 IGF and FGF cooperatively establish the regulatory stem cell niche of pluripotent human cells in vitro Nature 448 1015 1021 1:CAS:528: DC%2BD2sXps12ns7g%3D 17625568 (Pubitemid 47345578)
-
(2007)
Nature
, vol.448
, Issue.7157
, pp. 1015-1021
-
-
Bendall, S.C.1
Stewart, M.H.2
Menendez, P.3
George, D.4
Vijayaragavan, K.5
Werbowetski-Ogilvie, T.6
Ramos-Mejia, V.7
Rouleau, A.8
Yang, J.9
Bosse, M.10
Lajoie, G.11
Bhatia, M.12
-
68
-
-
77649241203
-
Screening the mammalian extracellular proteome for regulators of embryonic human stem cell pluripotency
-
Gonzalez R, Jennings LL, Knuth M, Orth AP, Klock HE, Ou W, Feuerhelm J, Hull MV, Koesema E, Wang Y, Zhang J, Wu C, Cho CY, Su AI, Batalov S, Chen H, Johnson K, Laffitte B, Nguyen DG, Snyder EY, Schultz PG, Harris JL, Lesley SA (2010) Screening the mammalian extracellular proteome for regulators of embryonic human stem cell pluripotency. Proc Natl Acad Sci USA 107:3552-3557
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 3552-3557
-
-
Gonzalez, R.1
Jennings, L.L.2
Knuth, M.3
Orth, A.P.4
Klock, H.E.5
Ou, W.6
Feuerhelm, J.7
Hull, M.V.8
Koesema, E.9
Wang, Y.10
Zhang, J.11
Wu, C.12
Cho, C.Y.13
Su, A.I.14
Batalov, S.15
Chen, H.16
Johnson, K.17
Laffitte, B.18
Nguyen, D.G.19
Snyder, E.Y.20
Schultz, P.G.21
Harris, J.L.22
Lesley, S.A.23
more..
-
69
-
-
37049008721
-
Self-renewal of human embryonic stem cells requires insulin-like growth factor-1 receptor and ERBB2 receptor signaling
-
DOI 10.1182/blood-2007-03-082586
-
L Wang TC Schulz ES Sherrer DS Dauphin S Shin AM Nelson CB Ware M Zhan CZ Song X Chen SN Brimble A McLean MJ Galeano EW Uhl KA D'Amour JD Chesnut MS Rao CA Blau AJ Robins 2007 Self-renewal of human embryonic stem cells requires insulin-like growth factor-1 receptor and ERBB2 receptor signaling Blood 110 4111 4119 1:CAS:528:DC%2BD2sXhtl2qsbzL 17761519 (Pubitemid 350248470)
-
(2007)
Blood
, vol.110
, Issue.12
, pp. 4111-4119
-
-
Wang, L.1
Schulz, T.C.2
Sherrer, E.S.3
Dauphin, D.S.4
Shin, S.5
Nelson, A.M.6
Ware, C.B.7
Zhan, M.8
Song, C.-Z.9
Chen, X.10
Brimble, S.N.11
McLean, A.12
Galeano, M.J.13
Uhl, E.W.14
D'Amour, K.A.15
Chesnut, J.D.16
Rao, M.S.17
Blau, C.A.18
Robins, A.J.19
-
70
-
-
33744758028
-
The role of PI3K/AKT, MAPK/ERK and NFκβ signalling in the maintenance of human embryonic stem cell pluripotency and viability highlighted by transcriptional profiling and functional analysis
-
DOI 10.1093/hmg/ddl112
-
L Armstrong O Hughes S Yung L Hyslop R Stewart I Wappler H Peters T Walter P Stojkovic J Evans M Stojkovic M Lako 2006 The role of PI3K/AKT, MAPK/ERK and NFkappabeta signalling in the maintenance of human embryonic stem cell pluripotency and viability highlighted by transcriptional profiling and functional analysis Hum Mol Genet 15 1894 1913 1:CAS:528:DC%2BD28Xksl2hu7c%3D 16644866 (Pubitemid 43821780)
-
(2006)
Human Molecular Genetics
, vol.15
, Issue.11
, pp. 1894-1913
-
-
Armstrong, L.1
Hughes, O.2
Yung, S.3
Hyslop, L.4
Stewart, R.5
Wappler, I.6
Peters, H.7
Walter, T.8
Stojkovic, P.9
Evans, J.10
Stojkovic, M.11
Lako, M.12
-
71
-
-
34547960488
-
MicroRNA functions
-
1:CAS:528:DC%2BD2sXhtlartr3M 17506695
-
N Bushati SM Cohen 2007 MicroRNA functions Annu Rev Cell Dev Biol 23 175 205 1:CAS:528:DC%2BD2sXhtlartr3M 17506695
-
(2007)
Annu Rev Cell Dev Biol
, vol.23
, pp. 175-205
-
-
Bushati, N.1
Cohen, S.M.2
-
72
-
-
77957967631
-
MicroRNAs in human embryonic and cancer stem cells
-
Navarro A, Monzo M MicroRNAs in human embryonic and cancer stem cells. Yonsei Med J 51:622-632
-
Yonsei Med J
, vol.51
, pp. 622-632
-
-
Navarro, A.1
Monzo, M.2
-
73
-
-
66149160608
-
Embryonic stem cell-specific micrornas promote induced pluripotency
-
1:CAS:528:DC%2BD1MXksVekt78%3D 19363475
-
RL Judson JE Babiarz M Venere R Blelloch 2009 Embryonic stem cell-specific micrornas promote induced pluripotency Nat Biotechnol 27 459 461 1:CAS:528:DC%2BD1MXksVekt78%3D 19363475
-
(2009)
Nat Biotechnol
, vol.27
, pp. 459-461
-
-
Judson, R.L.1
Babiarz, J.E.2
Venere, M.3
Blelloch, R.4
-
74
-
-
37549028759
-
MicroRNA expression pattern of undifferentiated and differentiated human embryonic stem cells
-
1:CAS:528:DC%2BD1cXhtVOnsw%3D%3D 18004940
-
U Lakshmipathy B Love LA Goff R Jornsten R Graichen RP Hart JD Chesnut 2007 MicroRNA expression pattern of undifferentiated and differentiated human embryonic stem cells Stem Cells Dev 16 1003 1016 1:CAS:528: DC%2BD1cXhtVOnsw%3D%3D 18004940
-
(2007)
Stem Cells Dev
, vol.16
, pp. 1003-1016
-
-
Lakshmipathy, U.1
Love, B.2
Goff, L.A.3
Jornsten, R.4
Graichen, R.5
Hart, R.P.6
Chesnut, J.D.7
-
75
-
-
73849085104
-
Identification of micrornas regulated by activin A in human embryonic stem cells
-
1:CAS:528:DC%2BD1MXhs1Sqt7jF 19885849
-
ZY Tsai S Singh SL Yu LP Kao BZ Chen BC Ho PC Yang SS Li 2010 Identification of micrornas regulated by activin A in human embryonic stem cells J Cell Biochem 109 93 102 1:CAS:528:DC%2BD1MXhs1Sqt7jF 19885849
-
(2010)
J Cell Biochem
, vol.109
, pp. 93-102
-
-
Tsai, Z.Y.1
Singh, S.2
Yu, S.L.3
Kao, L.P.4
Chen, B.Z.5
Ho, B.C.6
Yang, P.C.7
Li, S.S.8
-
76
-
-
79951576560
-
Identification of microRNAs expressed highly in pancreatic islet-like cell clusters differentiated from human embryonic stem cells
-
in press
-
Chen BZ, Yu SL, Singh S, Kao LP, Tsai ZY, Yang PC, Chen BH, Li SS (2010) Identification of microRNAs expressed highly in pancreatic islet-like cell clusters differentiated from human embryonic stem cells. Cell Biol Int (in press)
-
(2010)
Cell Biol Int
-
-
Chen, B.Z.1
Yu, S.L.2
Singh, S.3
Kao, L.P.4
Tsai, Z.Y.5
Yang, P.C.6
Chen, B.H.7
Li, S.S.8
-
77
-
-
77955603296
-
Live cell monitoring of hiPSC generation and differentiation using differential expression of endogenous microRNAs
-
20676373
-
M Kamata M Liang S Liu Y Nagaoka IS Chen 2010 Live cell monitoring of hiPSC generation and differentiation using differential expression of endogenous microRNAs PLoS One 5 e11834 20676373
-
(2010)
PLoS One
, vol.5
, pp. 11834
-
-
Kamata, M.1
Liang, M.2
Liu, S.3
Nagaoka, Y.4
Chen, I.S.5
-
79
-
-
67349149082
-
MicroRNA-145 regulates oct4, sox2, and klf4 and represses pluripotency in human embryonic stem cells
-
1:CAS:528:DC%2BD1MXosVCltrY%3D 19409607
-
N Xu T Papagiannakopoulos G Pan JA Thomson KS Kosik 2009 MicroRNA-145 regulates oct4, sox2, and klf4 and represses pluripotency in human embryonic stem cells Cell 137 647 658 1:CAS:528:DC%2BD1MXosVCltrY%3D 19409607
-
(2009)
Cell
, vol.137
, pp. 647-658
-
-
Xu, N.1
Papagiannakopoulos, T.2
Pan, G.3
Thomson, J.A.4
Kosik, K.S.5
-
80
-
-
0035480032
-
Anoikis mechanisms
-
DOI 10.1016/S0955-0674(00)00251-9
-
SM Frisch RA Screaton 2001 Anoikis mechanisms Curr Opin Cell Biol 13 555 562 1:CAS:528:DC%2BD3MXmsFersLs%3D 11544023 (Pubitemid 32817013)
-
(2001)
Current Opinion in Cell Biology
, vol.13
, Issue.5
, pp. 555-562
-
-
Frisch, S.M.1
Screaton, R.A.2
-
81
-
-
34250206996
-
A ROCK inhibitor permits survival of dissociated human embryonic stem cells
-
DOI 10.1038/nbt1310, PII NBT1310
-
K Watanabe M Ueno D Kamiya A Nishiyama M Matsumura T Wataya JB Takahashi S Nishikawa K Muguruma Y Sasai 2007 A rock inhibitor permits survival of dissociated human embryonic stem cells Nat Biotechnol 25 681 686 1:CAS:528:DC%2BD2sXmtlers7o%3D 17529971 (Pubitemid 46897207)
-
(2007)
Nature Biotechnology
, vol.25
, Issue.6
, pp. 681-686
-
-
Watanabe, K.1
Ueno, M.2
Kamiya, D.3
Nishiyama, A.4
Matsumura, M.5
Wataya, T.6
Takahashi, J.B.7
Nishikawa, S.8
Nishikawa, S.-I.9
Muguruma, K.10
Sasai, Y.11
-
82
-
-
71749114493
-
Inhibition of caspase-mediated anoikis is critical for basic fibroblast growth factor-sustained culture of human pluripotent stem cells
-
1:CAS:528:DC%2BD1MXhsVymu7nK 19828453
-
X Wang G Lin K Martins-Taylor H Zeng RH Xu 2009 Inhibition of caspase-mediated anoikis is critical for basic fibroblast growth factor-sustained culture of human pluripotent stem cells J Biol Chem 284 34054 34064 1:CAS:528:DC%2BD1MXhsVymu7nK 19828453
-
(2009)
J Biol Chem
, vol.284
, pp. 34054-34064
-
-
Wang, X.1
Lin, G.2
Martins-Taylor, K.3
Zeng, H.4
Xu, R.H.5
-
83
-
-
33644864033
-
Neurotrophins mediate human embryonic stem cell survival
-
DOI 10.1038/nbt1189, PII N1189
-
AD Pyle LF Lock PJ Donovan 2006 Neurotrophins mediate human embryonic stem cell survival Nat Biotechnol 24 344 350 1:CAS:528:DC%2BD28XitFGis7w%3D 16444268 (Pubitemid 43372159)
-
(2006)
Nature Biotechnology
, vol.24
, Issue.3
, pp. 344-350
-
-
Pyle, A.D.1
Lock, L.F.2
Donovan, P.J.3
-
84
-
-
38349062515
-
Human Es cell-derived neural rosettes reveal a functionally distinct early neural stem cell stage
-
1:CAS:528:DC%2BD1cXhtFOrsrg%3D 18198334
-
Y Elkabetz G Panagiotakos G Al Shamy ND Socci V Tabar L Studer 2008 Human Es cell-derived neural rosettes reveal a functionally distinct early neural stem cell stage Genes Dev 22 152 165 1:CAS:528:DC%2BD1cXhtFOrsrg%3D 18198334
-
(2008)
Genes Dev
, vol.22
, pp. 152-165
-
-
Elkabetz, Y.1
Panagiotakos, G.2
Al Shamy, G.3
Socci, N.D.4
Tabar, V.5
Studer, L.6
-
85
-
-
0035200623
-
In vitro differentiation of transplantable neural precursors from human embryonic stem cells
-
DOI 10.1038/nbt1201-1129
-
SC Zhang M Wernig ID Duncan O Brustle JA Thomson 2001 In vitro differentiation of transplantable neural precursors from human embryonic stem cells Nat Biotechnol 19 1129 1133 1:CAS:528:DC%2BD3MXptV2rtrc%3D 11731781 (Pubitemid 33115698)
-
(2001)
Nature Biotechnology
, vol.19
, Issue.12
, pp. 1129-1133
-
-
Zhang, S.-C.1
Wernig, M.2
Duncan, I.D.3
Brustle, O.4
Thomson, J.A.5
-
86
-
-
68549140371
-
Human ESC-derived neural rosettes and neural stem cell progression
-
1:CAS:528:DC%2BD1MXos1ertbY%3D 19204067
-
Y Elkabetz L Studer 2008 Human ESC-derived neural rosettes and neural stem cell progression Cold Spring Harb Symp Quant Biol 73 377 387 1:CAS:528:DC%2BD1MXos1ertbY%3D 19204067
-
(2008)
Cold Spring Harb Symp Quant Biol
, vol.73
, pp. 377-387
-
-
Elkabetz, Y.1
Studer, L.2
-
87
-
-
0035203881
-
Neural progenitors from human embryonic stem cells
-
DOI 10.1038/nbt1201-1134
-
BE Reubinoff P Itsykson T Turetsky MF Pera E Reinhartz A Itzik T Ben-Hur 2001 Neural progenitors from human embryonic stem cells Nat Biotechnol 19 1134 1140 1:CAS:528:DC%2BD3MXptV2rt70%3D 11731782 (Pubitemid 33115699)
-
(2001)
Nature Biotechnology
, vol.19
, Issue.12
, pp. 1134-1140
-
-
Reubinoff, B.E.1
Itsykson, P.2
Turetsky, T.3
Pera, M.F.4
Reinhartz, E.5
Itzik, A.6
Ben-Hur, T.7
-
88
-
-
59849107734
-
Human embryonic stem cell differentiation toward regional specific neural precursors
-
1:CAS:528:DC%2BD1MXisVeqsbY%3D 18845761
-
S Erceg M Ronaghi M Stojkovic 2009 Human embryonic stem cell differentiation toward regional specific neural precursors Stem Cells 27 78 87 1:CAS:528:DC%2BD1MXisVeqsbY%3D 18845761
-
(2009)
Stem Cells
, vol.27
, pp. 78-87
-
-
Erceg, S.1
Ronaghi, M.2
Stojkovic, M.3
-
90
-
-
0034633526
-
Effects of eight growth factors on the differentiation of cells derived from human embryonic stem cells
-
1:CAS:528:DC%2BD3cXnsF2ruro%3D 11027332
-
M Schuldiner O Yanuka J Itskovitz-Eldor DA Melton N Benvenisty 2000 Effects of eight growth factors on the differentiation of cells derived from human embryonic stem cells Proc Natl Acad Sci USA 97 11307 11312 1:CAS:528:DC%2BD3cXnsF2ruro%3D 11027332
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 11307-11312
-
-
Schuldiner, M.1
Yanuka, O.2
Itskovitz-Eldor, J.3
Melton, D.A.4
Benvenisty, N.5
-
91
-
-
33847646399
-
A scaleable and defined system for generating neural stem cells from human embryonic stem cells
-
DOI 10.1634/stemcells.2006-0562
-
AJ Joannides C Fiore-Heriche AA Battersby P Athauda-Arachchi IA Bouhon L Williams K Westmore PJ Kemp A Compston ND Allen S Chandran 2007 A scaleable and defined system for generating neural stem cells from human embryonic stem cells Stem Cells 25 731 737 1:CAS:528:DC%2BD2sXktlegsr4%3D 17095704 (Pubitemid 46354233)
-
(2007)
Stem Cells
, vol.25
, Issue.3
, pp. 731-737
-
-
Joannides, A.J.1
Fiore-Heriche, C.2
Battersby, A.A.3
Athauda-Arachchi, P.4
Bouhon, I.A.5
Williams, L.6
Westmore, K.7
Kemp, P.J.8
Compston, A.9
Allen, N.D.10
Chandran, S.11
-
92
-
-
23644455006
-
Derivation of neural precursors from human embryonic stem cells in the presence of noggin
-
DOI 10.1016/j.mcn.2005.05.004, PII S1044743105001119
-
P Itsykson N Ilouz T Turetsky RS Goldstein MF Pera I Fishbein M Segal BE Reubinoff 2005 Derivation of neural precursors from human embryonic stem cells in the presence of noggin Mol Cell Neurosci 30 24 36 1:CAS:528: DC%2BD2MXnslyju7w%3D 16081300 (Pubitemid 41133337)
-
(2005)
Molecular and Cellular Neuroscience
, vol.30
, Issue.1
, pp. 24-36
-
-
Itsykson, P.1
Ilouz, N.2
Turetsky, T.3
Goldstein, R.S.4
Pera, M.F.5
Fishbein, I.6
Segal, M.7
Reubinoff, B.E.8
-
93
-
-
69249202573
-
Highly efficient differentiation and enrichment of spinal motor neurons derived from human and monkey embryonic stem cells
-
19701462
-
T Wada M Honda I Minami N Tooi Y Amagai N Nakatsuji K Aiba 2009 Highly efficient differentiation and enrichment of spinal motor neurons derived from human and monkey embryonic stem cells PLoS One 4 e6722 19701462
-
(2009)
PLoS One
, vol.4
, pp. 6722
-
-
Wada, T.1
Honda, M.2
Minami, I.3
Tooi, N.4
Amagai, Y.5
Nakatsuji, N.6
Aiba, K.7
-
94
-
-
77953912037
-
Robust enhancement of neural differentiation from human ES and iPS cells regardless of their innate difference in differentiation propensity
-
1:CAS:528:DC%2BC3cXns1Cltr0%3D 20376579
-
DS Kim JS Lee JW Leem YJ Huh JY Kim HS Kim IH Park GQ Daley DY Hwang DW Kim 2010 Robust enhancement of neural differentiation from human ES and iPS cells regardless of their innate difference in differentiation propensity Stem Cell Rev 6 270 281 1:CAS:528:DC%2BC3cXns1Cltr0%3D 20376579
-
(2010)
Stem Cell Rev
, vol.6
, pp. 270-281
-
-
Kim, D.S.1
Lee, J.S.2
Leem, J.W.3
Huh, Y.J.4
Kim, J.Y.5
Kim, H.S.6
Park, I.H.7
Daley, G.Q.8
Hwang, D.Y.9
Kim, D.W.10
-
95
-
-
62149125434
-
Highly efficient neural conversion of human ES and iPS cells by dual inhibition of smad signaling
-
1:CAS:528:DC%2BD1MXisVOrtrc%3D 19252484
-
SM Chambers CA Fasano EP Papapetrou M Tomishima M Sadelain L Studer 2009 Highly efficient neural conversion of human ES and iPS cells by dual inhibition of smad signaling Nat Biotechnol 27 275 280 1:CAS:528:DC%2BD1MXisVOrtrc%3D 19252484
-
(2009)
Nat Biotechnol
, vol.27
, pp. 275-280
-
-
Chambers, S.M.1
Fasano, C.A.2
Papapetrou, E.P.3
Tomishima, M.4
Sadelain, M.5
Studer, L.6
-
96
-
-
20044383922
-
In vitro and in vivo analyses of human embryonic stem cell-derived dopamine neurons
-
DOI 10.1111/j.1471-4159.2004.03006.x
-
CH Park YK Minn JY Lee DH Choi MY Chang JW Shim JY Ko HC Koh MJ Kang JS Kang DJ Rhie YS Lee H Son SY Moon KS Kim SH Lee 2005 In vitro and in vivo analyses of human embryonic stem cell-derived dopamine neurons J Neurochem 92 1265 1276 1:CAS:528:DC%2BD2MXitlehsrg%3D 15715675 (Pubitemid 40344315)
-
(2005)
Journal of Neurochemistry
, vol.92
, Issue.5
, pp. 1265-1276
-
-
Park, C.-H.1
Minn, Y.-K.2
Lee, J.-Y.3
Choi, D.H.4
Chang, M.-Y.5
Shim, J.-W.6
Ko, J.-Y.7
Koh, H.-C.8
Kang, M.J.9
Kang, J.S.10
Rhie, D.-J.11
Lee, Y.-S.12
Son, H.13
Moon, S.Y.14
Kim, K.-S.15
Lee, S.-H.16
-
97
-
-
8644259350
-
Dopaminergic differentiation of human embryonic stem cells
-
X Zeng J Cai J Chen Y Luo ZB You E Fotter Y Wang B Harvey T Miura C Backman GJ Chen MS Rao WJ Freed 2004 Dopaminergic differentiation of human embryonic stem cells Stem Cells 22 925 940 1:CAS:528:DC%2BD2cXhtFSiu7bL 15536184 (Pubitemid 39507080)
-
(2004)
Stem Cells
, vol.22
, Issue.6
, pp. 925-940
-
-
Zeng, X.1
Cai, J.2
Chen, J.3
Luo, Y.4
You, Z.-B.5
Fotter, E.6
Wang, Y.7
Harvey, B.8
Miura, T.9
Backman, C.10
Chen, G.-J.11
Rao, M.S.12
Freed, W.J.13
-
98
-
-
4444308824
-
Generation of tyrosine hydroxylase positive neurons from human embryonic stem cells after coculture with cellular substrates and exposure to GDNF
-
KA Buytaert-Hoefen E Alvarez CR Freed 2004 Generation of tyrosine hydroxylase positive neurons from human embryonic stem cells after coculture with cellular substrates and exposure to GDNF Stem Cells 22 669 674 1:CAS:528:DC%2BD2cXnvFOlur4%3D 15342931 (Pubitemid 39166925)
-
(2004)
Stem Cells
, vol.22
, Issue.5
, pp. 669-674
-
-
Buytaert-Hoefen, K.A.1
Alvarez, E.2
Freed, C.R.3
-
99
-
-
4344592974
-
Derivation of midbrain dopamine neurons from human embryonic stem cells
-
DOI 10.1073/pnas.0404700101
-
AL Perrier V Tabar T Barberi ME Rubio J Bruses N Topf NL Harrison L Studer 2004 Derivation of midbrain dopamine neurons from human embryonic stem cells Proc Natl Acad Sci USA 101 12543 12548 1:CAS:528:DC%2BD2cXnsVensLc%3D 15310843 (Pubitemid 39122060)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.34
, pp. 12543-12548
-
-
Perrier, A.L.1
Tabar, V.2
Barberi, T.3
Rubio, M.E.4
Bruses, J.5
Topf, N.6
Harrison, N.L.7
Studer, L.8
-
100
-
-
10744229091
-
Neural subtype specification of fertilization and nuclear transfer embryonic stem cells and application in parkinsonian mice
-
DOI 10.1038/nbt870
-
T Barberi P Klivenyi NY Calingasan H Lee H Kawamata K Loonam AL Perrier J Bruses ME Rubio N Topf V Tabar NL Harrison MF Beal MA Moore L Studer 2003 Neural subtype specification of fertilization and nuclear transfer embryonic stem cells and application in parkinsonian mice Nat Biotechnol 21 1200 1207 1:CAS:528:DC%2BD3sXns1Clsbg%3D 14502203 (Pubitemid 37186177)
-
(2003)
Nature Biotechnology
, vol.21
, Issue.10
, pp. 1200-1207
-
-
Barberi, T.1
Klivenyi, P.2
Calingasan, N.Y.3
Lee, H.4
Kawamata, H.5
Loonam, K.6
Perrier, A.L.7
Bruses, J.8
Rubio, M.E.9
Topf, N.10
Tabar, V.11
Harrison, N.L.12
Beal, M.F.13
Moore, M.A.S.14
Studer, L.15
-
101
-
-
37349128901
-
Neural precursors derived from human embryonic stem cells maintain long-term proliferation without losing the potential to differentiate into all three neural lineages, including dopaminergic neurons
-
DOI 10.1111/j.1471-4159.2007.04952.x
-
S Hong UJ Kang O Isacson KS Kim 2008 Neural precursors derived from human embryonic stem cells maintain long-term proliferation without losing the potential to differentiate into all three neural lineages, including dopaminergic neurons J Neurochem 104 316 324 1:CAS:528:DC%2BD1cXhtlSqsr8%3D 17944878 (Pubitemid 350293864)
-
(2008)
Journal of Neurochemistry
, vol.104
, Issue.2
, pp. 316-324
-
-
Hong, S.1
Kang, U.J.2
Isacson, O.3
Kim, K.-S.4
-
102
-
-
70349880527
-
Conditions for tumor-free and dopamine neuron-enriched grafts after transplanting human ES cell-derived neural precursor cells
-
1:CAS:528:DC%2BD1MXosFWhsro%3D 19603007
-
JY Ko HS Lee CH Park HC Koh YS Lee SH Lee 2009 Conditions for tumor-free and dopamine neuron-enriched grafts after transplanting human ES cell-derived neural precursor cells Mol Ther 17 1761 1770 1:CAS:528:DC%2BD1MXosFWhsro%3D 19603007
-
(2009)
Mol Ther
, vol.17
, pp. 1761-1770
-
-
Ko, J.Y.1
Lee, H.S.2
Park, C.H.3
Koh, H.C.4
Lee, Y.S.5
Lee, S.H.6
-
103
-
-
0033638174
-
Induction of midbrain dopaminergic neurons from ES cells by stromal cell-derived inducing activity
-
1:CAS:528:DC%2BD3cXnvVGlt78%3D 11086981
-
H Kawasaki K Mizuseki S Nishikawa S Kaneko Y Kuwana S Nakanishi SI Nishikawa Y Sasai 2000 Induction of midbrain dopaminergic neurons from ES cells by stromal cell-derived inducing activity Neuron 28 31 40 1:CAS:528: DC%2BD3cXnvVGlt78%3D 11086981
-
(2000)
Neuron
, vol.28
, pp. 31-40
-
-
Kawasaki, H.1
Mizuseki, K.2
Nishikawa, S.3
Kaneko, S.4
Kuwana, Y.5
Nakanishi, S.6
Nishikawa, S.I.7
Sasai, Y.8
-
104
-
-
0037022299
-
Generation of dopaminergic neurons and pigmented epithelia from primate ES cells by stromal cell-derived inducing activity
-
DOI 10.1073/pnas.032662199
-
H Kawasaki H Suemori K Mizuseki K Watanabe F Urano H Ichinose M Haruta M Takahashi K Yoshikawa S Nishikawa N Nakatsuji Y Sasai 2002 Generation of dopaminergic neurons and pigmented epithelia from primate ES cells by stromal cell-derived inducing activity Proc Natl Acad Sci USA 99 1580 1585 1:CAS:528:DC%2BD38Xht1Cltrk%3D 11818560 (Pubitemid 34136535)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.3
, pp. 1580-1585
-
-
Kawasaki, H.1
Suemori, H.2
Mizuseki, K.3
Watanabe, K.4
Urano, F.5
Ichinose, H.6
Haruta, M.7
Takahashi, M.8
Yoshikawa, K.9
Nishikawa, S.-I.10
Nakatsuji, N.11
Sasai, Y.12
-
105
-
-
0034136393
-
Differentiation of human embryonic stem cells into embryoid bodies compromising the three embryonic germ layers
-
1:STN:280:DC%2BD3cvgt1WksA%3D%3D 10859025
-
J Itskovitz-Eldor M Schuldiner D Karsenti A Eden O Yanuka M Amit H Soreq N Benvenisty 2000 Differentiation of human embryonic stem cells into embryoid bodies compromising the three embryonic germ layers Mol Med 6 88 95 1:STN:280:DC%2BD3cvgt1WksA%3D%3D 10859025
-
(2000)
Mol Med
, vol.6
, pp. 88-95
-
-
Itskovitz-Eldor, J.1
Schuldiner, M.2
Karsenti, D.3
Eden, A.4
Yanuka, O.5
Amit, M.6
Soreq, H.7
Benvenisty, N.8
-
106
-
-
11144354441
-
Generation of dopaminergic neurons in vitro from human embryonic stem cells treated with neurotrophic factors
-
DOI 10.1016/j.neulet.2004.01.073, PII S0304394004001429
-
S Park KS Lee YJ Lee HA Shin HY Cho KC Wang YS Kim HT Lee KS Chung EY Kim J Lim 2004 Generation of dopaminergic neurons in vitro from human embryonic stem cells treated with neurotrophic factors Neurosci Lett 359 99 103 1:CAS:528:DC%2BD2cXisF2ns78%3D 15050721 (Pubitemid 38446648)
-
(2004)
Neuroscience Letters
, vol.359
, Issue.1-2
, pp. 99-103
-
-
Park, S.1
Lee, K.S.2
Lee, Y.J.3
Shin, H.A.4
Cho, H.Y.5
Wang, K.C.6
Kim, Y.S.7
Lee, H.T.8
Chung, K.S.9
Kim, E.Y.10
Lim, J.11
-
108
-
-
62549127853
-
A rosette-type, self-renewing human ES cell-derived neural stem cell with potential for in vitro instruction and synaptic integration
-
1:CAS:528:DC%2BD1MXivF2jsrc%3D 19218428
-
P Koch T Opitz JA Steinbeck J Ladewig O Brustle 2009 A rosette-type, self-renewing human ES cell-derived neural stem cell with potential for in vitro instruction and synaptic integration Proc Natl Acad Sci USA 106 3225 3230 1:CAS:528:DC%2BD1MXivF2jsrc%3D 19218428
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 3225-3230
-
-
Koch, P.1
Opitz, T.2
Steinbeck, J.A.3
Ladewig, J.4
Brustle, O.5
-
109
-
-
65249134409
-
Development of human nervous tissue upon differentiation of embryonic stem cells in three-dimensional culture
-
O Preynat-Seauve DM Suter D Tirefort L Turchi T Virolle H Chneiweiss M Foti JA Lobrinus L Stoppini A Feki M Dubois-Dauphin KH Krause 2009 Development of human nervous tissue upon differentiation of embryonic stem cells in three-dimensional culture Stem Cells 27 509 520
-
(2009)
Stem Cells
, vol.27
, pp. 509-520
-
-
Preynat-Seauve, O.1
Suter, D.M.2
Tirefort, D.3
Turchi, L.4
Virolle, T.5
Chneiweiss, H.6
Foti, M.7
Lobrinus, J.A.8
Stoppini, L.9
Feki, A.10
Dubois-Dauphin, M.11
Krause, K.H.12
-
110
-
-
70450159769
-
Coordination of sonic hedgehog and Wnt signaling determines ventral and dorsal telencephalic neuron types from human embryonic stem cells
-
1:CAS:528:DC%2BC3cXislSkug%3D%3D 19906872
-
XJ Li X Zhang MA Johnson ZB Wang T Lavaute SC Zhang 2009 Coordination of sonic hedgehog and Wnt signaling determines ventral and dorsal telencephalic neuron types from human embryonic stem cells Development 136 4055 4063 1:CAS:528:DC%2BC3cXislSkug%3D%3D 19906872
-
(2009)
Development
, vol.136
, pp. 4055-4063
-
-
Li, X.J.1
Zhang, X.2
Johnson, M.A.3
Wang, Z.B.4
Lavaute, T.5
Zhang, S.C.6
-
111
-
-
34547102737
-
Directed neural differentiation of human embryonic stem cells via an obligated primitive anterior stage
-
DOI 10.1634/stemcells.2006-0707
-
MT Pankratz XJ Li TM Lavaute EA Lyons X Chen SC Zhang 2007 Directed neural differentiation of human embryonic stem cells via an obligated primitive anterior stage Stem Cells 25 1511 1520 1:CAS:528:DC%2BD2sXntlWrtL0%3D 17332508 (Pubitemid 47106020)
-
(2007)
Stem Cells
, vol.25
, Issue.6
, pp. 1511-1520
-
-
Pankratz, M.T.1
Li, X.-J.2
LaVaute, T.M.3
Lyons, E.A.4
Chen, X.5
Zhang, S.-C.6
-
112
-
-
77957664853
-
Pax6 is a human neuroectoderm cell fate determinant
-
1:CAS:528:DC%2BC3cXps12kt74%3D 20621053
-
X Zhang CT Huang J Chen MT Pankratz J Xi J Li Y Yang T Lavaute XJ Li M Ayala GI Bondarenko ZW Du Y Jin TG Golos SC Zhang 2010 Pax6 is a human neuroectoderm cell fate determinant Cell Stem Cell 7 90 100 1:CAS:528: DC%2BC3cXps12kt74%3D 20621053
-
(2010)
Cell Stem Cell
, vol.7
, pp. 90-100
-
-
Zhang, X.1
Huang, C.T.2
Chen, J.3
Pankratz, M.T.4
Xi, J.5
Li, J.6
Yang, Y.7
Lavaute, T.8
Li, X.J.9
Ayala, M.10
Bondarenko, G.I.11
Du, Z.W.12
Jin, Y.13
Golos, T.G.14
Zhang, S.C.15
-
113
-
-
70349569241
-
Notch signaling is required for maintaining stem-cell features of neuroprogenitor cells derived from human embryonic stem cells
-
19682396
-
SM Woo J Kim HW Han JI Chae MY Son S Cho HM Chung YM Han YK Kang 2009 Notch signaling is required for maintaining stem-cell features of neuroprogenitor cells derived from human embryonic stem cells BMC Neurosci 10 97 19682396
-
(2009)
BMC Neurosci
, vol.10
, pp. 97
-
-
Woo, S.M.1
Kim, J.2
Han, H.W.3
Chae, J.I.4
Son, M.Y.5
Cho, S.6
Chung, H.M.7
Han, Y.M.8
Kang, Y.K.9
-
114
-
-
47749108736
-
Differentiation of human embryonic stem cells to regional specific neural precursors in chemically defined medium conditions
-
18461168
-
S Erceg S Lainez M Ronaghi P Stojkovic MA Perez-Arago V Moreno-Manzano R Moreno-Palanques R Planells-Cases M Stojkovic 2008 Differentiation of human embryonic stem cells to regional specific neural precursors in chemically defined medium conditions PLoS One 3 e2122 18461168
-
(2008)
PLoS One
, vol.3
, pp. 2122
-
-
Erceg, S.1
Lainez, S.2
Ronaghi, M.3
Stojkovic, P.4
Perez-Arago, M.A.5
Moreno-Manzano, V.6
Moreno-Palanques, R.7
Planells-Cases, R.8
Stojkovic, M.9
-
115
-
-
34047191826
-
Midbrain dopamine neuron differentiation: Factors and fates
-
DOI 10.1016/j.ydbio.2007.01.032, PII S0012160607000656
-
A Abeliovich R Hammond 2007 Midbrain dopamine neuron differentiation: factors and fates Dev Biol 304 447 454 1:CAS:528:DC%2BD2sXjvFeht7g%3D 17331494 (Pubitemid 46527580)
-
(2007)
Developmental Biology
, vol.304
, Issue.2
, pp. 447-454
-
-
Abeliovich, A.1
Hammond, R.2
-
116
-
-
0032966607
-
Specification of dopaminergic and serotonergic neurons in the vertebrate CNS
-
DOI 10.1016/S0959-4388(99)80004-X
-
M Hynes A Rosenthal 1999 Specification of dopaminergic and serotonergic neurons in the vertebrate CNS Curr Opin Neurobiol 9 26 36 1:CAS:528: DyaK1MXhvVWitbo%3D 10072377 (Pubitemid 29084087)
-
(1999)
Current Opinion in Neurobiology
, vol.9
, Issue.1
, pp. 26-36
-
-
Hynes, M.1
Rosenthal, A.2
-
117
-
-
0041409985
-
The isthmic organizer signal FGF8 is required for cell survival in the prospective midbrain and cerebellum
-
DOI 10.1242/dev.00487
-
CL Chi S Martinez W Wurst GR Martin 2003 The isthmic organizer signal FGF8 is required for cell survival in the prospective midbrain and cerebellum Development 130 2633 2644 1:CAS:528:DC%2BD3sXltFartrs%3D 12736208 (Pubitemid 37069580)
-
(2003)
Development
, vol.130
, Issue.12
, pp. 2633-2644
-
-
Chi, C.L.1
Martinez, S.2
Wurst, W.3
Martin, G.R.4
-
118
-
-
20344368813
-
Directed differentiation of dopaminergic neuronal subtypes from human embryonic stem cells
-
DOI 10.1634/stemcells.2004-0365
-
Y Yan D Yang ED Zarnowska Z Du B Werbel C Valliere RA Pearce JA Thomson SC Zhang 2005 Directed differentiation of dopaminergic neuronal subtypes from human embryonic stem cells Stem Cells 23 781 790 1:CAS:528:DC%2BD2MXlslCltb8%3D 15917474 (Pubitemid 40791793)
-
(2005)
Stem Cells
, vol.23
, Issue.6
, pp. 781-790
-
-
Yan, Y.1
Yang, D.2
Zarnowska, E.D.3
Du, Z.4
Werbel, B.5
Valliere, C.6
Pearce, R.A.7
Thomson, J.A.8
Zhang, S.-C.9
-
119
-
-
0038452606
-
Transforming growth factor-βs are essential for the development of midbrain dopaminergic neurons in vitro and in vivo
-
LM Farkas N Dunker E Roussa K Unsicker K Krieglstein 2003 Transforming growth factor-beta(s) are essential for the development of midbrain dopaminergic neurons in vitro and in vivo J Neurosci 23 5178 5186 1:CAS:528: DC%2BD3sXltlentLs%3D 12832542 (Pubitemid 36793246)
-
(2003)
Journal of Neuroscience
, vol.23
, Issue.12
, pp. 5178-5186
-
-
Farkas, L.M.1
Dunker, N.2
Roussa, E.3
Unsicker, K.4
Krieglstein, K.5
-
120
-
-
68949130137
-
A novel combination of factors, termed SPIE, which promotes dopaminergic neuron differentiation from human embryonic stem cells
-
19672298
-
T Vazin KG Becker J Chen CE Spivak CR Lupica Y Zhang L Worden WJ Freed 2009 A novel combination of factors, termed SPIE, which promotes dopaminergic neuron differentiation from human embryonic stem cells PLoS One 4 e6606 19672298
-
(2009)
PLoS One
, vol.4
, pp. 6606
-
-
Vazin, T.1
Becker, K.G.2
Chen, J.3
Spivak, C.E.4
Lupica, C.R.5
Zhang, Y.6
Worden, L.7
Freed, W.J.8
-
121
-
-
70349309626
-
Liver X receptors and oxysterols promote ventral midbrain neurogenesis in vivo and in human embryonic stem cells
-
1:CAS:528:DC%2BD1MXhsVCjtrvK 19796621
-
P Sacchetti KM Sousa AC Hall I Liste KR Steffensen S Theofilopoulos CL Parish C Hazenberg LA Richter O Hovatta JA Gustafsson E Arenas 2009 Liver X receptors and oxysterols promote ventral midbrain neurogenesis in vivo and in human embryonic stem cells Cell Stem Cell 5 409 419 1:CAS:528:DC%2BD1MXhsVCjtrvK 19796621
-
(2009)
Cell Stem Cell
, vol.5
, pp. 409-419
-
-
Sacchetti, P.1
Sousa, K.M.2
Hall, A.C.3
Liste, I.4
Steffensen, K.R.5
Theofilopoulos, S.6
Parish, C.L.7
Hazenberg, C.8
Richter, L.A.9
Hovatta, O.10
Gustafsson, J.A.11
Arenas, E.12
-
123
-
-
0033754542
-
Genetic and epigenetic control of midbrain dopaminergic neuron development
-
1:CAS:528:DC%2BD3cXotlyrtbc%3D 11061432
-
C Perrone-Capano U Di Porzio 2000 Genetic and epigenetic control of midbrain dopaminergic neuron development Int J Dev Biol 44 679 687 1:CAS:528:DC%2BD3cXotlyrtbc%3D 11061432
-
(2000)
Int J Dev Biol
, vol.44
, pp. 679-687
-
-
Perrone-Capano, C.1
Di Porzio, U.2
-
124
-
-
79954607367
-
Association of transcription factor polymorphisms PITX3 and EN1 with Parkinson's disease
-
(in press)
-
Haubenberger D, Reinthaler E, Mueller JC, Pirker W, Katzenschlager R, Froehlich R, Bruecke T, Daniel G, Auff E, Zimprich A (2009) Association of transcription factor polymorphisms PITX3 and EN1 with Parkinson's disease. Neurobiol Aging (in press)
-
(2009)
Neurobiol Aging
-
-
Haubenberger, D.1
Reinthaler, E.2
Mueller, J.C.3
Pirker, W.4
Katzenschlager, R.5
Froehlich, R.6
Bruecke, T.7
Daniel, G.8
Auff, E.9
Zimprich, A.10
-
125
-
-
0038389745
-
Transcriptional control of dopamine neuron development
-
A Wallen T Perlmann 2003 Transcriptional control of dopamine neuron development Ann N Y Acad Sci 991 48 60 1:CAS:528:DC%2BD3sXmtVCkur0%3D 12846973 (Pubitemid 36793800)
-
(2003)
Annals of the New York Academy of Sciences
, vol.991
, pp. 48-60
-
-
Wallen, A.1
Perlmann, T.2
-
126
-
-
33644531535
-
Cooperative transcription activation by NURR1 and PITX3 induces embryonic stem cell maturation to the midbrain dopamine neuron phenotype
-
1:CAS:528:DC%2BD28XksF2rtbs%3D 16477036
-
C Martinat JJ Bacci T Leete J Kim WB Vanti AH Newman JH Cha U Gether H Wang A Abeliovich 2006 Cooperative transcription activation by NURR1 and PITX3 induces embryonic stem cell maturation to the midbrain dopamine neuron phenotype Proc Natl Acad Sci USA 103 2874 2879 1:CAS:528:DC%2BD28XksF2rtbs%3D 16477036
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 2874-2879
-
-
Martinat, C.1
Bacci, J.J.2
Leete, T.3
Kim, J.4
Vanti, W.B.5
Newman, A.H.6
Cha, J.H.7
Gether, U.8
Wang, H.9
Abeliovich, A.10
-
127
-
-
59849099441
-
The role of Lmx1a in the differentiation of human embryonic stem cells into midbrain dopamine neurons in culture and after transplantation into a Parkinson 's disease model
-
1:CAS:528:DC%2BD1MXisVeqt70%3D 18832589
-
J Cai A Donaldson M Yang MS German G Enikolopov L Iacovitti 2009 The role of Lmx1a in the differentiation of human embryonic stem cells into midbrain dopamine neurons in culture and after transplantation into a Parkinson 's disease model Stem Cells 27 220 229 1:CAS:528:DC%2BD1MXisVeqt70%3D 18832589
-
(2009)
Stem Cells
, vol.27
, pp. 220-229
-
-
Cai, J.1
Donaldson, A.2
Yang, M.3
German, M.S.4
Enikolopov, G.5
Iacovitti, L.6
-
128
-
-
66149085781
-
Efficient production of mesencephalic dopamine neurons by Lmx1a expression in embryonic stem cells
-
1:CAS:528:DC%2BD1MXmt1Krsr4%3D 19383789
-
S Friling E Andersson LH Thompson ME Jonsson JB Hebsgaard E Nanou Z Alekseenko U Marklund S Kjellander N Volakakis O Hovatta A El Manira A Bjorklund T Perlmann J Ericson 2009 Efficient production of mesencephalic dopamine neurons by Lmx1a expression in embryonic stem cells Proc Natl Acad Sci USA 106 7613 7618 1:CAS:528:DC%2BD1MXmt1Krsr4%3D 19383789
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 7613-7618
-
-
Friling, S.1
Andersson, E.2
Thompson, L.H.3
Jonsson, M.E.4
Hebsgaard, J.B.5
Nanou, E.6
Alekseenko, Z.7
Marklund, U.8
Kjellander, S.9
Volakakis, N.10
Hovatta, O.11
El Manira, A.12
Bjorklund, A.13
Perlmann, T.14
Ericson, J.15
-
129
-
-
33749186818
-
Transforming growth factor β is required for differentiation of mouse mesencephalic progenitors into dopaminergic neurons in vitro and in vivo: Ectopic induction in dorsal mesencephalon
-
DOI 10.1634/stemcells.2005-0514
-
E Roussa M Wiehle N Dunker S Becker-Katins O Oehlke K Krieglstein 2006 Transforming growth factor beta is required for differentiation of mouse mesencephalic progenitors into dopaminergic neurons in vitro and in vivo: ectopic induction in dorsal mesencephalon Stem Cells 24 2120 2129 1:CAS:528:DC%2BD28XhtFKgs7zM 16741229 (Pubitemid 44477137)
-
(2006)
Stem Cells
, vol.24
, Issue.9
, pp. 2120-2129
-
-
Roussa, E.1
Wiehle, M.2
Dunker, N.3
Becker-Katins, S.4
Oehlke, O.5
Krieglstein, K.6
-
130
-
-
55049122063
-
Transforming growth factor beta cooperates with persephin for dopaminergic phenotype induction
-
1:CAS:528:DC%2BD1cXpvV2murk%3D 18420832
-
E Roussa O Oehlke B Rahhal S Heermann S Heidrich M Wiehle K Krieglstein 2008 Transforming growth factor beta cooperates with persephin for dopaminergic phenotype induction Stem Cells 26 1683 1694 1:CAS:528:DC%2BD1cXpvV2murk%3D 18420832
-
(2008)
Stem Cells
, vol.26
, pp. 1683-1694
-
-
Roussa, E.1
Oehlke, O.2
Rahhal, B.3
Heermann, S.4
Heidrich, S.5
Wiehle, M.6
Krieglstein, K.7
-
131
-
-
0031975391
-
Transforming growth factor-βS in neurodegenerative disease
-
DOI 10.1016/S0301-0082(97)00066-X, PII S030100829700066X
-
KC Flanders RF Ren CF Lippa 1998 Transforming growth factor-betas in neurodegenerative disease Prog Neurobiol 54 71 85 1:CAS:528:DyaK1cXmsl2ksQ%3D%3D 9460794 (Pubitemid 28049820)
-
(1998)
Progress in Neurobiology
, vol.54
, Issue.1
, pp. 71-85
-
-
Flanders, K.C.1
Ren, R.F.2
Lippa, C.F.3
-
132
-
-
0034949608
-
Differentiation of embryonic stem cell-derived dopaminergic neurons is enhanced by survival-promoting factors
-
DOI 10.1016/S0925-4773(01)00385-9, PII S0925477301003859
-
A Rolletschek H Chang K Guan J Czyz M Meyer AM Wobus 2001 Differentiation of embryonic stem cell-derived dopaminergic neurons is enhanced by survival-promoting factors Mech Dev 105 93 104 1:CAS:528:DC%2BD3MXks1Omtb4%3D 11429285 (Pubitemid 32586762)
-
(2001)
Mechanisms of Development
, vol.105
, Issue.1-2
, pp. 93-104
-
-
Rolletschek, A.1
Chang, H.2
Guan, K.3
Czyz, J.4
Meyer, M.5
Wobus, A.M.6
-
133
-
-
0032487422
-
CAMP included during cell suspension preparation improves survival of dopaminergic neurons in vitro
-
RL Branton RM Love DJ Clarke 1998 cAMP included during cell suspension preparation improves survival of dopaminergic neurons in vitro Neuroreport 9 3223 3227 1:CAS:528:DyaK1cXnsFCisb4%3D 9831455 (Pubitemid 28522340)
-
(1998)
NeuroReport
, vol.9
, Issue.14
, pp. 3223-3227
-
-
Branton, R.L.1
Love, R.M.2
Clarke, D.J.3
-
134
-
-
0025876757
-
BDNF is a neurotrophic factor for dopaminergic neurons of the substantia nigra
-
C Hyman M Hofer YA Barde M Juhasz GD Yancopoulos SP Squinto RM Lindsay 1991 BDNF is a neurotrophic factor for dopaminergic neurons of the substantia nigra Nature 350 230 232 1:CAS:528:DyaK3MXhslyrtr8%3D 2005978 (Pubitemid 21912205)
-
(1991)
Nature
, vol.350
, Issue.6315
, pp. 230-232
-
-
Hyman, C.1
Hofer, M.2
Barde, Y.-A.3
Juhasz, M.4
Yancopoulos, G.D.5
Squinto, S.P.6
Lindsay, R.M.7
-
135
-
-
21544446985
-
Brain-derived neurotrophic factor is required for the establishment of the proper number of dopaminergic neurons in the substantia nigra pars compacta
-
DOI 10.1523/JNEUROSCI.4601-04.2005
-
ZC Baquet PC Bickford KR Jones 2005 Brain-derived neurotrophic factor is required for the establishment of the proper number of dopaminergic neurons in the substantia nigra pars compacta J Neurosci 25 6251 6259 1:CAS:528: DC%2BD2MXmtFKntb4%3D 15987955 (Pubitemid 40923492)
-
(2005)
Journal of Neuroscience
, vol.25
, Issue.26
, pp. 6251-6259
-
-
Baquet, Z.C.1
Bickford, P.C.2
Jones, K.R.3
-
136
-
-
51349094603
-
Combined use of BDNF, ascorbic acid, low oxygen, and prolonged differentiation time generates tyrosine hydroxylase-expressing neurons after long-term in vitro expansion of human fetal midbrain precursor cells
-
1:CAS:528:DC%2BD1cXhtFamsrnJ 18652826
-
J Maciaczyk I Singec D Maciaczyk G Nikkhah 2008 Combined use of BDNF, ascorbic acid, low oxygen, and prolonged differentiation time generates tyrosine hydroxylase-expressing neurons after long-term in vitro expansion of human fetal midbrain precursor cells Exp Neurol 213 354 362 1:CAS:528: DC%2BD1cXhtFamsrnJ 18652826
-
(2008)
Exp Neurol
, vol.213
, pp. 354-362
-
-
MacIaczyk, J.1
Singec, I.2
MacIaczyk, D.3
Nikkhah, G.4
-
137
-
-
42149107420
-
Highly efficient and large-scale generation of functional dopamine neurons from human embryonic stem cells
-
DOI 10.1073/pnas.0712359105
-
MS Cho YE Lee JY Kim S Chung YH Cho DS Kim SM Kang H Lee MH Kim JH Kim JW Leem SK Oh YM Choi DY Hwang JW Chang DW Kim 2008 Highly efficient and large-scale generation of functional dopamine neurons from human embryonic stem cells Proc Natl Acad Sci USA 105 3392 3397 1:CAS:528:DC%2BD1cXjtlKkt7o%3D 18305158 (Pubitemid 351723563)
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.9
, pp. 3392-3397
-
-
Myung, S.C.1
Lee, Y.-E.2
Ji, Y.K.3
Chung, S.4
Yoon, H.C.5
Kim, D.-S.6
Kang, S.-M.7
Lee, H.8
Kim, M.-H.9
Kim, J.-H.10
Joong, W.L.11
Sun, K.O.12
Young, M.C.13
Hwang, D.-Y.14
Jin, W.C.15
Kim, D.-W.16
-
138
-
-
0034303585
-
Neuronal specification in the spinal cord: Inductive signals and transcriptional codes
-
1:CAS:528:DC%2BD3cXotlGls78%3D 11262869
-
TM Jessell 2000 Neuronal specification in the spinal cord: inductive signals and transcriptional codes Nat Rev Genet 1 20 29 1:CAS:528: DC%2BD3cXotlGls78%3D 11262869
-
(2000)
Nat Rev Genet
, vol.1
, pp. 20-29
-
-
Jessell, T.M.1
-
139
-
-
0037023529
-
Common developmental requirement for Olig function indicates a motor neuron/oligodendrocyte connection
-
DOI 10.1016/S0092-8674(02)00678-5
-
QR Lu T Sun Z Zhu N Ma M Garcia CD Stiles DH Rowitch 2002 Common developmental requirement for olig function indicates a motor neuron/oligodendrocyte connection Cell 109 75 86 1:CAS:528:DC%2BD38XjtVOntLw%3D 11955448 (Pubitemid 34327518)
-
(2002)
Cell
, vol.109
, Issue.1
, pp. 75-86
-
-
Lu Q.Richard1
Sun, T.2
Zhu, Z.3
Ma, N.4
Garcia, M.5
Stiles, C.D.6
Rowitch, D.H.7
-
140
-
-
0033593304
-
Progression from extrinsic to intrinsic signaling in cell fate specification: A view from the nervous system
-
DOI 10.1016/S0092-8674(00)80561-9
-
T Edlund TM Jessell 1999 Progression from extrinsic to intrinsic signaling in cell fate specification: a view from the nervous system Cell 96 211 224 1:CAS:528:DyaK1MXotlyrug%3D%3D 9988216 (Pubitemid 29059351)
-
(1999)
Cell
, vol.96
, Issue.2
, pp. 211-224
-
-
Edlund, T.1
Jessell, T.M.2
-
141
-
-
0033179908
-
Active suppression of interneuron programs within developing motor neurons revealed by analysis of homeodomain factor HB9
-
DOI 10.1016/S0896-6273(01)80027-1
-
J Thaler K Harrison K Sharma K Lettieri J Kehrl SL Pfaff 1999 Active suppression of interneuron programs within developing motor neurons revealed by analysis of homeodomain factor HB9 Neuron 23 675 687 1:CAS:528: DyaK1MXmtVWqu78%3D 10482235 (Pubitemid 29411558)
-
(1999)
Neuron
, vol.23
, Issue.4
, pp. 675-687
-
-
Thaler, J.1
Harrison, K.2
Sharma, K.3
Lettieri, K.4
Kehrl, J.5
Pfaff, S.L.6
-
142
-
-
0034601506
-
Genetic and epigenetic mechanisms contribute to motor neuron pathfinding
-
DOI 10.1038/35020078
-
K Sharma AE Leonard K Lettieri SL Pfaff 2000 Genetic and epigenetic mechanisms contribute to motor neuron pathfinding Nature 406 515 519 1:CAS:528:DC%2BD3cXmtFegt74%3D 10952312 (Pubitemid 30625735)
-
(2000)
Nature
, vol.406
, Issue.6795
, pp. 515-519
-
-
Sharma, K.1
Leonard, A.E.2
Lettieri, K.3
Pfaff, S.L.4
-
143
-
-
0033143881
-
The specification of neuronal identity by graded sonic hedgehog signalling
-
J Briscoe J Ericson 1999 The specification of neuronal identity by graded sonic hedgehog signalling Semin Cell Dev Biol 10 353 362 1:CAS:528: DyaK1MXlsFygsrY%3D 10441550 (Pubitemid 129502430)
-
(1999)
Seminars in Cell and Developmental Biology
, vol.10
, Issue.3
, pp. 353-362
-
-
Briscoe, J.1
Ericson, J.2
-
144
-
-
0442278332
-
Early steps in the development of the forebrain
-
DOI 10.1016/S1534-5807(04)00027-9, PII S1534580704000279
-
SW Wilson C Houart 2004 Early steps in the development of the forebrain Dev Cell 6 167 181 1:CAS:528:DC%2BD2cXhs1Smu70%3D 14960272 (Pubitemid 38190359)
-
(2004)
Developmental Cell
, vol.6
, Issue.2
, pp. 167-181
-
-
Wilson, S.W.1
Houart, C.2
-
145
-
-
70249133666
-
Differentiation of spinal motor neurons from pluripotent human stem cells
-
1:CAS:528:DC%2BD1MXhtVygsLfN 19696748
-
BY Hu SC Zhang 2009 Differentiation of spinal motor neurons from pluripotent human stem cells Nat Protoc 4 1295 1304 1:CAS:528:DC%2BD1MXhtVygsLfN 19696748
-
(2009)
Nat Protoc
, vol.4
, pp. 1295-1304
-
-
Hu, B.Y.1
Zhang, S.C.2
-
146
-
-
45849146018
-
Directed differentiation of ventral spinal progenitors and motor neurons from human embryonic stem cells by small molecules
-
1:CAS:528:DC%2BD1cXmtFKltLc%3D 18238853
-
XJ Li BY Hu SA Jones YS Zhang T Lavaute ZW Du SC Zhang 2008 Directed differentiation of ventral spinal progenitors and motor neurons from human embryonic stem cells by small molecules Stem Cells 26 886 893 1:CAS:528:DC%2BD1cXmtFKltLc%3D 18238853
-
(2008)
Stem Cells
, vol.26
, pp. 886-893
-
-
Li, X.J.1
Hu, B.Y.2
Jones, S.A.3
Zhang, Y.S.4
Lavaute, T.5
Du, Z.W.6
Zhang, S.C.7
-
147
-
-
33645211374
-
Purmorphamine activates the hedgehog pathway by targeting smoothened
-
1:CAS:528:DC%2BD2MXhtlSqu7jM 16408088
-
S Sinha JK Chen 2006 Purmorphamine activates the hedgehog pathway by targeting smoothened Nat Chem Biol 2 29 30 1:CAS:528:DC%2BD2MXhtlSqu7jM 16408088
-
(2006)
Nat Chem Biol
, vol.2
, pp. 29-30
-
-
Sinha, S.1
Chen, J.K.2
-
148
-
-
27744438009
-
Enhancer-specified GFP-based FACS purification of human spinal motor neurons from embryonic stem cells
-
DOI 10.1016/j.expneurol.2005.06.021, PII S0014488605002293
-
N Singh Roy T Nakano L Xuing J Kang M Nedergaard SA Goldman 2005 Enhancer-specified GFP-based FACS purification of human spinal motor neurons from embryonic stem cells Exp Neurol 196 224 234 16198339 (Pubitemid 41607810)
-
(2005)
Experimental Neurology
, vol.196
, Issue.2
, pp. 224-234
-
-
Singh Roy, N.1
Nakano, T.2
Xuing, L.3
Kang, J.4
Nedergaard, M.5
Goldman, S.A.6
-
149
-
-
0029965068
-
Combined effects of GDNF, BDNF, and CNTF on motoneuron differentiation in vitro
-
DOI 10.1002/(SICI)1097-4547(19960415)44:2<133::AID-JNR5>3.0.CO;2-E
-
AD Zurn L Winkel A Menoud K Djabali P Aebischer 1996 Combined effects of GDNF, BDNF, AND CNTF on motoneuron differentiation in vitro J Neurosci Res 44 133 141 1:CAS:528:DyaK28Xis1Cjsrk%3D 8723221 (Pubitemid 26134404)
-
(1996)
Journal of Neuroscience Research
, vol.44
, Issue.2
, pp. 133-141
-
-
Zurn, A.D.1
Winkel, L.2
Menoud, A.3
Djabali, K.4
Aebischer, P.5
-
150
-
-
67651206063
-
Stem cells: Comprehensive treatments for amyotrophic lateral sclerosis in conjunction with growth factor delivery
-
1:CAS:528:DC%2BD1MXotlagtr8%3D 19294549
-
JS Lunn MP Hefferan M Marsala EL Feldman 2009 Stem cells: comprehensive treatments for amyotrophic lateral sclerosis in conjunction with growth factor delivery Growth Factors 27 133 140 1:CAS:528:DC%2BD1MXotlagtr8%3D 19294549
-
(2009)
Growth Factors
, vol.27
, pp. 133-140
-
-
Lunn, J.S.1
Hefferan, M.P.2
Marsala, M.3
Feldman, E.L.4
-
151
-
-
27144449720
-
A balance of FGF, BMP and WNT signaling positions the future placode territory in the head
-
DOI 10.1242/dev.01964
-
A Litsiou S Hanson A Streit 2005 A balance of FGF, BMP and Wnt signalling positions the future placode territory in the head Development 132 4051 4062 1:CAS:528:DC%2BD2MXhtFCgs77E 16093325 (Pubitemid 41488855)
-
(2005)
Development
, vol.132
, Issue.18
, pp. 4051-4062
-
-
Litsiou, A.1
Hanson, S.2
Streit, A.3
-
152
-
-
18744373024
-
Induction and specification of the vertebrate ectodermal placodes: Precursors of the cranial sensory organs
-
DOI 10.1042/BC20040515
-
SA Brugmann SA Moody 2005 Induction and specification of the vertebrate ectodermal placodes: precursors of the cranial sensory organs Biol Cell 97 303 319 15836430 (Pubitemid 40668201)
-
(2005)
Biology of the Cell
, vol.97
, Issue.5
, pp. 303-319
-
-
Brugmann, S.A.1
Moody, S.A.2
-
153
-
-
36048934978
-
The preplacodal region: An ectodermal domain with multipotential progenitors that contribute to sense organs and cranial sensory ganglia
-
DOI 10.1387/ijdb.072327as
-
A Streit 2007 The preplacodal region: an ectodermal domain with multipotential progenitors that contribute to sense organs and cranial sensory ganglia Int J Dev Biol 51 447 461 1:CAS:528:DC%2BD1cXivVSgsA%3D%3D 17891708 (Pubitemid 350084402)
-
(2007)
International Journal of Developmental Biology
, vol.51
, Issue.6-7
, pp. 447-461
-
-
Streit, A.1
-
154
-
-
33645545584
-
Competence of cranial ectoderm to respond to FGF signaling suggests a two-step model of otic placode induction
-
1:CAS:528:DC%2BD28XjtlKnsrw%3D 16452090
-
K Martin AK Groves 2006 Competence of cranial ectoderm to respond to FGF signaling suggests a two-step model of otic placode induction Development 133 877 887 1:CAS:528:DC%2BD28XjtlKnsrw%3D 16452090
-
(2006)
Development
, vol.133
, pp. 877-887
-
-
Martin, K.1
Groves, A.K.2
-
155
-
-
77954060569
-
Derivation of neural crest cells from human pluripotent stem cells
-
1:CAS:528:DC%2BC3cXksVWksbY%3D 20360764
-
G Lee SM Chambers MJ Tomishima L Studer 2010 Derivation of neural crest cells from human pluripotent stem cells Nat Protoc 5 688 701 1:CAS:528:DC%2BC3cXksVWksbY%3D 20360764
-
(2010)
Nat Protoc
, vol.5
, pp. 688-701
-
-
Lee, G.1
Chambers, S.M.2
Tomishima, M.J.3
Studer, L.4
-
156
-
-
38849203129
-
Peripheral sensory neurons differentiate from neural precursors derived from human embryonic stem cells
-
DOI 10.1111/j.1432-0436.2007.00196.x
-
I Brokhman L Gamarnik-Ziegler O Pomp M Aharonowiz BE Reubinoff RS Goldstein 2008 Peripheral sensory neurons differentiate from neural precursors derived from human embryonic stem cells Differentiation 76 145 155 1:CAS:528:DC%2BD1cXivFersLY%3D 17608731 (Pubitemid 351197175)
-
(2008)
Differentiation
, vol.76
, Issue.2
, pp. 145-155
-
-
Brokhman, I.1
Gamarnik-Ziegler, L.2
Pomp, O.3
Aharonowiz, M.4
Reubinoff, B.E.5
Goldstein, R.S.6
-
157
-
-
53149122825
-
Derivation of cranial neural crest-like cells from human embryonic stem cells
-
1:CAS:528:DC%2BD1cXht1ensrfP 18804450
-
Y Zhou ML Snead 2008 Derivation of cranial neural crest-like cells from human embryonic stem cells Biochem Biophys Res Commun 376 542 547 1:CAS:528:DC%2BD1cXht1ensrfP 18804450
-
(2008)
Biochem Biophys Res Commun
, vol.376
, pp. 542-547
-
-
Zhou, Y.1
Snead, M.L.2
-
158
-
-
23844463469
-
Generation of peripheral sensory and sympathetic neurons and neural crest cells from human embryonic stem cells
-
DOI 10.1634/stemcells.2005-0038
-
O Pomp I Brokhman I Ben-Dor B Reubinoff RS Goldstein 2005 Generation of peripheral sensory and sympathetic neurons and neural crest cells from human embryonic stem cells Stem Cells 23 923 930 1:CAS:528:DC%2BD2MXhtVemsrbP 15883233 (Pubitemid 41170948)
-
(2005)
Stem Cells
, vol.23
, Issue.7
, pp. 923-930
-
-
Pomp, O.1
Brokhman, I.2
Ben-Dor, I.3
Reubinoff, B.4
Goldstein, R.S.5
-
159
-
-
65349166659
-
Genetic modification of human embryonic stem cells with adenoviral vectors: Differences of infectability between lines and correlation of infectability with expression of the coxsackie and adenovirus receptor
-
1:CAS:528:DC%2BD1MXkvVGgsLk%3D 18554086
-
I Brokhman O Pomp L Fishman T Tennenbaum M Amit J Itzkovitz-Eldor RS Goldstein 2009 Genetic modification of human embryonic stem cells with adenoviral vectors: differences of infectability between lines and correlation of infectability with expression of the coxsackie and adenovirus receptor Stem Cells Dev 18 447 456 1:CAS:528:DC%2BD1MXkvVGgsLk%3D 18554086
-
(2009)
Stem Cells Dev
, vol.18
, pp. 447-456
-
-
Brokhman, I.1
Pomp, O.2
Fishman, L.3
Tennenbaum, T.4
Amit, M.5
Itzkovitz-Eldor, J.6
Goldstein, R.S.7
-
160
-
-
70349418034
-
Isolation and characterization of neural crest stem cells derived from in vitro-differentiated human embryonic stem cells
-
1:CAS:528:DC%2BD1MXhtFWhtb7K 19099373
-
X Jiang Y Gwye SJ McKeown M Bronner-Fraser C Lutzko ER Lawlor 2009 Isolation and characterization of neural crest stem cells derived from in vitro-differentiated human embryonic stem cells Stem Cells Dev 18 1059 1070 1:CAS:528:DC%2BD1MXhtFWhtb7K 19099373
-
(2009)
Stem Cells Dev
, vol.18
, pp. 1059-1070
-
-
Jiang, X.1
Gwye, Y.2
McKeown, S.J.3
Bronner-Fraser, M.4
Lutzko, C.5
Lawlor, E.R.6
-
161
-
-
73349120563
-
Small-molecule induction of neural crest-like cells derived from human neural progenitors
-
1:CAS:528:DC%2BC3cXhsVCqsbc%3D 19711454
-
R Hotta L Pepdjonovic RB Anderson D Zhang AJ Bergner J Leung A Pebay HM Young DF Newgreen M Dottori 2009 Small-molecule induction of neural crest-like cells derived from human neural progenitors Stem Cells 27 2896 2905 1:CAS:528:DC%2BC3cXhsVCqsbc%3D 19711454
-
(2009)
Stem Cells
, vol.27
, pp. 2896-2905
-
-
Hotta, R.1
Pepdjonovic, L.2
Anderson, R.B.3
Zhang, D.4
Bergner, A.J.5
Leung, J.6
Pebay, A.7
Young, H.M.8
Newgreen, D.F.9
Dottori, M.10
-
162
-
-
77949517646
-
Enriched population of pns neurons derived from human embryonic stem cells as a platform for studying peripheral neuropathies
-
20174633
-
M Valensi-Kurtz S Lefler MA Cohen M Aharonowiz R Cohen-Kupiec A Sheinin U Ashery B Reubinoff M Weil 2010 Enriched population of pns neurons derived from human embryonic stem cells as a platform for studying peripheral neuropathies PLoS One 5 e9290 20174633
-
(2010)
PLoS One
, vol.5
, pp. 9290
-
-
Valensi-Kurtz, M.1
Lefler, S.2
Cohen, M.A.3
Aharonowiz, M.4
Cohen-Kupiec, R.5
Sheinin, A.6
Ashery, U.7
Reubinoff, B.8
Weil, M.9
-
163
-
-
36849062137
-
Isolation and directed differentiation of neural crest stem cells derived from human embryonic stem cells
-
DOI 10.1038/nbt1365, PII NBT1365
-
G Lee H Kim Y Elkabetz G Al Shamy G Panagiotakos T Barberi V Tabar L Studer 2007 Isolation and directed differentiation of neural crest stem cells derived from human embryonic stem cells Nat Biotechnol 25 1468 1475 1:CAS:528:DC%2BD2sXhsVSjurvJ 18037878 (Pubitemid 350233140)
-
(2007)
Nature Biotechnology
, vol.25
, Issue.12
, pp. 1468-1475
-
-
Lee, G.1
Kim, H.2
Elkabetz, Y.3
Al Shamy, G.4
Panagiotakos, G.5
Barberi, T.6
Tabar, V.7
Studer, L.8
-
164
-
-
31544441632
-
Derivation of human embryonic stem cell lines from embryos obtained after IVF and after PGD for monogenic disorders
-
DOI 10.1093/humrep/dei345
-
I Mateizel N De Temmerman U Ullmann G Cauffman K Sermon H Van de Velde M De Rycke E Degreef P Devroey I Liebaers A Van Steirteghem 2006 Derivation of human embryonic stem cell lines from embryos obtained after IVF and after PGD for monogenic disorders Hum Reprod 21 503 511 1:STN:280:DC%2BD28%2FosVaksw%3D%3D 16284066 (Pubitemid 43159929)
-
(2006)
Human Reproduction
, vol.21
, Issue.2
, pp. 503-511
-
-
Mateizel, I.1
De Temmerman, N.2
Ullmann, U.3
Cauffman, G.4
Sermon, K.5
Van De Velde, H.6
De Rycke, M.7
Degreef, E.8
Devroey, P.9
Liebaers, I.10
Van Steirteghem, A.11
-
165
-
-
61349100729
-
Parkinson's disease patient-derived induced pluripotent stem cells free of viral reprogramming factors
-
1:CAS:528:DC%2BD1MXltFSnsb0%3D 19269371
-
F Soldner D Hockemeyer C Beard Q Gao GW Bell EG Cook G Hargus A Blak O Cooper M Mitalipova O Isacson R Jaenisch 2009 Parkinson's disease patient-derived induced pluripotent stem cells free of viral reprogramming factors Cell 136 964 977 1:CAS:528:DC%2BD1MXltFSnsb0%3D 19269371
-
(2009)
Cell
, vol.136
, pp. 964-977
-
-
Soldner, F.1
Hockemeyer, D.2
Beard, C.3
Gao, Q.4
Bell, G.W.5
Cook, E.G.6
Hargus, G.7
Blak, A.8
Cooper, O.9
Mitalipova, M.10
Isacson, O.11
Jaenisch, R.12
-
166
-
-
50549089957
-
Disease-specific induced pluripotent stem cells
-
1:CAS:528:DC%2BD1cXhtFCqs7bK 18691744
-
IH Park N Arora H Huo N Maherali T Ahfeldt A Shimamura MW Lensch C Cowan K Hochedlinger GQ Daley 2008 Disease-specific induced pluripotent stem cells Cell 134 877 886 1:CAS:528:DC%2BD1cXhtFCqs7bK 18691744
-
(2008)
Cell
, vol.134
, pp. 877-886
-
-
Park, I.H.1
Arora, N.2
Huo, H.3
Maherali, N.4
Ahfeldt, T.5
Shimamura, A.6
Lensch, M.W.7
Cowan, C.8
Hochedlinger, K.9
Daley, G.Q.10
-
167
-
-
50149098605
-
Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons
-
1:CAS:528:DC%2BD1cXhtVGgt7zL 18669821
-
JT Dimos KT Rodolfa KK Niakan LM Weisenthal H Mitsumoto W Chung GF Croft G Saphier R Leibel R Goland H Wichterle CE Henderson K Eggan 2008 Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons Science 321 1218 1221 1:CAS:528:DC%2BD1cXhtVGgt7zL 18669821
-
(2008)
Science
, vol.321
, pp. 1218-1221
-
-
Dimos, J.T.1
Rodolfa, K.T.2
Niakan, K.K.3
Weisenthal, L.M.4
Mitsumoto, H.5
Chung, W.6
Croft, G.F.7
Saphier, G.8
Leibel, R.9
Goland, R.10
Wichterle, H.11
Henderson, C.E.12
Eggan, K.13
-
168
-
-
33745034833
-
Transcription Impairment and Cell Migration Defects in Elongator-Depleted Cells: Implication for Familial Dysautonomia
-
DOI 10.1016/j.molcel.2006.04.017, PII S1097276506002656
-
P Close N Hawkes I Cornez C Creppe CA Lambert B Rogister U Siebenlist MP Merville SA Slaugenhaupt V Bours JQ Svejstrup A Chariot 2006 Transcription impairment and cell migration defects in elongator-depleted cells: implication for familial dysautonomia Mol Cell 22 521 531 1:CAS:528:DC%2BD28XlsFWhsrs%3D 16713582 (Pubitemid 44255542)
-
(2006)
Molecular Cell
, vol.22
, Issue.4
, pp. 521-531
-
-
Close, P.1
Hawkes, N.2
Cornez, I.3
Creppe, C.4
Lambert, C.A.5
Rogister, B.6
Siebenlist, U.7
Merville, M.-P.8
Slaugenhaupt, S.A.9
Bours, V.10
Svejstrup, J.Q.11
Chariot, A.12
-
169
-
-
59349089711
-
Elongator controls the migration and differentiation of cortical neurons through acetylation of alpha-tubulin
-
1:CAS:528:DC%2BD1MXltFSns78%3D 19185337
-
C Creppe L Malinouskaya ML Volvert M Gillard P Close O Malaise S Laguesse I Cornez S Rahmouni S Ormenese S Belachew B Malgrange JP Chapelle U Siebenlist G Moonen A Chariot L Nguyen 2009 Elongator controls the migration and differentiation of cortical neurons through acetylation of alpha-tubulin Cell 136 551 564 1:CAS:528:DC%2BD1MXltFSns78%3D 19185337
-
(2009)
Cell
, vol.136
, pp. 551-564
-
-
Creppe, C.1
Malinouskaya, L.2
Volvert, M.L.3
Gillard, M.4
Close, P.5
Malaise, O.6
Laguesse, S.7
Cornez, I.8
Rahmouni, S.9
Ormenese, S.10
Belachew, S.11
Malgrange, B.12
Chapelle, J.P.13
Siebenlist, U.14
Moonen, G.15
Chariot, A.16
Nguyen, L.17
-
170
-
-
70349301819
-
Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs
-
1:CAS:528:DC%2BD1MXhtVWhsbjL 19693009
-
G Lee EP Papapetrou H Kim SM Chambers MJ Tomishima CA Fasano YM Ganat J Menon F Shimizu A Viale V Tabar M Sadelain L Studer 2009 Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs Nature 461 402 406 1:CAS:528:DC%2BD1MXhtVWhsbjL 19693009
-
(2009)
Nature
, vol.461
, pp. 402-406
-
-
Lee, G.1
Papapetrou, E.P.2
Kim, H.3
Chambers, S.M.4
Tomishima, M.J.5
Fasano, C.A.6
Ganat, Y.M.7
Menon, J.8
Shimizu, F.9
Viale, A.10
Tabar, V.11
Sadelain, M.12
Studer, L.13
|