Hydrogels as artificial matrices for human embryonic stem cell self-renewal

Journal of Biomedical Materials Research - Part A

Volumn 79, Issue 1, 2006, Pages 1-5

  Li, Ying J ^a   Chung, Eugene H ^a   Rodriguez, Ryan T ^b   Firpo, Meri T ^c   Healy, Kevin E ^a,d,e  

^a University of California at Berkeley   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e NONE   (United States)

Author keywords

Artificial extracellular matrices; Human embryonic stem cells; Hydrogels; Interpenetrating networks; Self renewal

Indexed keywords

BIOMEDICAL ENGINEERING; CELL CULTURE; INTERPENETRATING POLYMER NETWORKS; SELF ASSEMBLY; STIFFNESS MATRIX;

ARTIFICIAL EXTRACELLULAR MATRICES; HUMAN EMBRYONIC STEM CELLS (HESC); SELF-RENEWAL; SYNTHETIC ECMS;

HYDROGELS;

ANIMAL CELL; ARTICLE; CELL ADHESION; CELL CULTURE; CELL DIFFERENTIATION; CELL RENEWAL; CELL STRUCTURE; CELL VIABILITY; CONTROLLED STUDY; CROSS LINKING; EMBRYO; EMBRYONIC STEM CELL; EXTRACELLULAR MATRIX; FIBROBLAST; HUMAN; HUMAN CELL; HYDROGEL; MOUSE; NONHUMAN; REGENERATION;

BIOCOMPATIBLE MATERIALS; CELL LINE; CELLS, CULTURED; HUMANS; HYDROGELS; STEM CELLS;

EID: 33748966882     PISSN: 00219304     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.30732     Document Type: Article

References (17)

1. Thomson JA, Itskovitz-Eldor J, Shapiro SS, Waknitz MA, Swiergiel JJ, Marshall VS, Jones JM. Embryonic stem cell lines derived from human blastocysts. Science 1998;282(5391):1145-1147.
2. Reubinoff BE, Pera MF, Fong CY, Trounson A, Bongso A. Embryonic stem cell lines from human blastocysts: Somatic differentiation in vitro. Nat Biotechnol 2000;18(4):399-404.
3. Richards M, Fong CY, Chan WK, Wong PC, Bongso A. Human feeders support prolonged undifferentiated growth of human inner cell masses and embryonic stem cells. Nat Biotechnol 2002;20(9):933-936.
4. Xu C, Inokuma MS, Denham J, Golds K, Kundu P, Gold JD, Carpenter MK. Feeder-free growth of undifferentiated human embryonic stem cells. Nat Biotechnol 2001;19(10):971-974.
5. Cheng L, Hammond H, Ye Z, Zhan X, Dravid G. Human adult marrow cells support prolonged expansion of human embryonic stem cells in culture. Stem Cell 2003;21(2):131-142.
6. Semler EJ, Ranucci CS, Moghe PV. Mechanochemical manipulation of hepatocyte aggregation can selectively induce or repress liver-specific function. Biotechnol Bioeng 2000;69(4):359-369.
7. Stile RA, Burghardt WR, Healy KE. Synthesis and characterization of injectable poly(n-isopropylacrylamide)-based hydrogels that support tissue formation in vitro. Macromolecules 1999;32(22):7370-7379.
8. Kim S, Healy KE. Synthesis and characterization of injectable poly(N-isopropylacrylamide-co-acrylic acid) hydrogels with proteolytically degradable cross-links. Biomacromolecules 2003;4(5):1214-1223.
9. Engler AJ, Griffin MA, Sen S, Bonnemann CG, Sweeney HL, Discher DE. Myotubes differentiate optimally on substrates with tissue-like stiffness: Pathological implications for soft or stiff microenvironments. J Cell Biol 2004;166(6):877-887.
10. Lo CM, Wang HB, Dembo M, Wang YL. Cell movement is guided by the rigidity of the substrate. Biophys J 2000;79(1):144-152.
11. Yeung T, Georges PC, Flanagan LA, Marg B, Ortiz M, Funaki M, Zahir N, Ming W, Weaver V, Janmey PA. Effects of substrate stiffness on cell morphology, cytoskeletal structure, and adhesion. Cell Motil Cytoskeleton 2005;60(1):24-34.
12. Rezania A, Healy KE. Integrin subunits responsible for adhesion of human osteoblast-like cells to biomimetic peptide surfaces. J Orthop Res 1999;17(4):615-623.
13. Kim S, Chung EH, Gilbert M, Healy KE. Synthetic MMP-13 degradable ECMs based on poly(N-isopropylacrylamide-co-acrylic acid) semi-interpenetrating polymer networks. I. Degradation and cell migration. J Biomed Mater Res A 2005;75(1):73-88.
14. Bodnar MS, Meneses JJ, Rodriguez RT, Firpo MT. Propagation and maintenance of undifferentiated human embryonic stem cells. Stem Cells Dev 2004;13(3):243-253.
15. BD Falcon Cell Culture Products. Falcon uses a vacuum gas-plasma process to create hydrophilic surfaces on tissue-culture polystrene. www.bdbiosciences.com.
16. Abeyta MJ, Clark AT, Rodriguez RT, Bodnar MS, Pera RA, Firpo MT. Unique gene expression signatures of independently-derived human embryonic stem cell lines. Hum Mol Genet 2004;13(6):601-608.
17. Martin MJ, Muotri A, Gage F, Varki A. Human embryonic stem cells express an immunogenic nonhuman sialic acid. Nat Med 2005;11(2):228-232.