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Volumn 130, Issue 12, 2003, Pages 2633-2644

The isthmic organizer signal FGF8 is required for cell survival in the prospective midbrain and cerebellum

Author keywords

Brain patterning; Cerebellum; Fgf8; Isthmic organizer; Mes met; Mesencephalon; Metencephalon; Midbrain; Midbrain hindbrain organizer; Mouse; Rhombomere 1

Indexed keywords

FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 17; FIBROBLAST GROWTH FACTOR 18; FIBROBLAST GROWTH FACTOR 8; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GBX2; UNCLASSIFIED DRUG; WNT PROTEIN; CRE RECOMBINASE; EN1 PROTEIN, MOUSE; FGF8 PROTEIN, MOUSE; HOMEODOMAIN PROTEIN; INTEGRASE; ONCOPROTEIN; VIRUS PROTEIN; WNT1 PROTEIN; WNT1 PROTEIN, MOUSE; ZEBRAFISH PROTEIN;

EID: 0041409985     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: 10.1242/dev.00487     Document Type: Review
Times cited : (280)

References (74)
  • 1
    • 0027525512 scopus 로고
    • Fate and potentialities of the avian mesencephalic/metencephalic neuroepithelium
    • Alvarado-Mallart, R. M. (1993). Fate and potentialities of the avian mesencephalic/metencephalic neuroepithelium. J. Neurobiol. 24, 1341-1355.
    • (1993) J. Neurobiol. , vol.24 , pp. 1341-1355
    • Alvarado-Mallart, R.M.1
  • 2
    • 0029163144 scopus 로고
    • Involvement of Wnt-1 in the formation of the mes/metencephalic boundary
    • Bally-Cuif, L., Cholley, B. and Wassef, M. (1995). Involvement of Wnt-1 in the formation of the mes/metencephalic boundary. Mech. Dev. 53, 23-34.
    • (1995) Mech. Dev. , vol.53 , pp. 23-34
    • Bally-Cuif, L.1    Cholley, B.2    Wassef, M.3
  • 3
    • 0033828647 scopus 로고    scopus 로고
    • Functional equivalence of the transcription factors Pax2 and Pax5 in mouse development
    • Bouchard, M., Pfeffer, P. and Busslinger, M. (2000). Functional equivalence of the transcription factors Pax2 and Pax5 in mouse development. Development 127, 3703-3713.
    • (2000) Development , vol.127 , pp. 3703-3713
    • Bouchard, M.1    Pfeffer, P.2    Busslinger, M.3
  • 4
    • 0028828216 scopus 로고
    • Sequence and expression pattern of the Stra7 (Gbx-2) homeobox-containing gene induced by retinoic acid in P19 embryonal carcinoma cells
    • Bouillet, P., Chazaud, C., Oulad-Abdelghani, M., Dolle, P. and Chambon, P. (1995). Sequence and expression pattern of the Stra7 (Gbx-2) homeobox-containing gene induced by retinoic acid in P19 embryonal carcinoma cells. Dev. Dyn. 204, 372-382.
    • (1995) Dev. Dyn. , vol.204 , pp. 372-382
    • Bouillet, P.1    Chazaud, C.2    Oulad-Abdelghani, M.3    Dolle, P.4    Chambon, P.5
  • 6
    • 0035461440 scopus 로고    scopus 로고
    • Molecular genetics of cranial nerve development in mouse
    • Cordes, S. P. (2001). Molecular genetics of cranial nerve development in mouse. Nat. Rev. Neurosci. 2, 611-623.
    • (2001) Nat. Rev. Neurosci. , vol.2 , pp. 611-623
    • Cordes, S.P.1
  • 7
    • 0028959288 scopus 로고
    • The mouse Fgf8 gene encodes a family of polypeptides and is expressed in regions that direct outgrowth and patterning in the developing embryo
    • Crossley, P. H. and Martin, G. R. (1995). The mouse Fgf8 gene encodes a family of polypeptides and is expressed in regions that direct outgrowth and patterning in the developing embryo. Development 121, 439-451.
    • (1995) Development , vol.121 , pp. 439-451
    • Crossley, P.H.1    Martin, G.R.2
  • 8
    • 0029960330 scopus 로고    scopus 로고
    • Midbrain development induced by FGF8 in the chick embryo
    • Crossley, P. H., Martinez, S. and Martin, G. R. (1996). Midbrain development induced by FGF8 in the chick embryo. Nature 380, 66-68.
    • (1996) Nature , vol.380 , pp. 66-68
    • Crossley, P.H.1    Martinez, S.2    Martin, G.R.3
  • 9
    • 0029742465 scopus 로고    scopus 로고
    • Engrailed-1 as a target of the Wnt-1 signalling pathway in vertebrate midbrain development
    • Danielian, P. S. and McMahon, A. P. (1996). Engrailed-1 as a target of the Wnt-1 signalling pathway in vertebrate midbrain development. Nature 383, 332-334.
    • (1996) Nature , vol.383 , pp. 332-334
    • Danielian, P.S.1    McMahon, A.P.2
  • 10
    • 0026101890 scopus 로고
    • Examining pattern formation in mouse, chicken and frog embryos with an En-specific antiserum
    • Davis, C. A., Holmyard, D. P., Millen, K. J. and Joyner, A. L. (1991). Examining pattern formation in mouse, chicken and frog embryos with an En-specific antiserum. Development 111, 287-298.
    • (1991) Development , vol.111 , pp. 287-298
    • Davis, C.A.1    Holmyard, D.P.2    Millen, K.J.3    Joyner, A.L.4
  • 11
    • 0024227273 scopus 로고
    • Expression patterns of the homeo box-containing genes En-1 and En-2 and the proto-oncogene int-1 diverge during mouse development
    • Davis, C. A. and Joyner, A. L. (1988). Expression patterns of the homeo box-containing genes En-1 and En-2 and the proto-oncogene int-1 diverge during mouse development. Genes Dev. 2, 1736-1744.
    • (1988) Genes Dev. , vol.2 , pp. 1736-1744
    • Davis, C.A.1    Joyner, A.L.2
  • 12
    • 0028229495 scopus 로고
    • Evidence for a mitogenic effect of Wnt-1 in the developing mammalian central nervous system
    • Dickinson, M. E., Krumlauf, R. and McMahon, A. P. (1994). Evidence for a mitogenic effect of Wnt-1 in the developing mammalian central nervous system. Development 120, 1453-1471.
    • (1994) Development , vol.120 , pp. 1453-1471
    • Dickinson, M.E.1    Krumlauf, R.2    McMahon, A.P.3
  • 13
    • 0023986284 scopus 로고
    • Spatial regulation of axonal glycoprotein expression on subsets of embryonic spinal neurons
    • Dodd, J., Morton, S. B., Karagogeos, D., Yamamoto, M. and Jessell, T. M. 1988). Spatial regulation of axonal glycoprotein expression on subsets of embryonic spinal neurons. Neuron 1, 105-116.
    • (1988) Neuron , vol.1 , pp. 105-116
    • Dodd, J.1    Morton, S.B.2    Karagogeos, D.3    Yamamoto, M.4    Jessell, T.M.5
  • 14
    • 0034904642 scopus 로고    scopus 로고
    • Inhibition of zebrafish fgf8 pre-mRNA splicing with morpholino oligos: A quantifiable method for gene knockdown
    • Draper, B. W., Morcos, P. A. and Kimmel, C. B. (2001). Inhibition of zebrafish fgf8 pre-mRNA splicing with morpholino oligos: a quantifiable method for gene knockdown. Genesis 30, 154-156.
    • (2001) Genesis , vol.30 , pp. 154-156
    • Draper, B.W.1    Morcos, P.A.2    Kimmel, C.B.3
  • 15
    • 0025118546 scopus 로고
    • Pax2, a new murine paired-box-containing gene and its expression in the developing excretory system
    • Dressler, G. R., Deutsch, U., Chowdhury, K., Nornes, H. O. and Gruss, P. (1990). Pax2, a new murine paired-box-containing gene and its expression in the developing excretory system. Development 109, 787-795.
    • (1990) Development , vol.109 , pp. 787-795
    • Dressler, G.R.1    Deutsch, U.2    Chowdhury, K.3    Nornes, H.O.4    Gruss, P.5
  • 16
    • 0037007119 scopus 로고    scopus 로고
    • Cell signaling: Life or death decisions of ras proteins
    • Feig, L. A. and Buchsbaum, R. J. (2002). Cell signaling: life or death decisions of ras proteins. Curr. Biol. 12, R259-R261.
    • (2002) Curr. Biol. , vol.12
    • Feig, L.A.1    Buchsbaum, R.J.2
  • 17
    • 0035114788 scopus 로고    scopus 로고
    • Neuroepithelial co-expression of Gbx2 and Otx2 precedes Fgf8 expression in the isthmic organizer
    • Garda, A. L., Echevarria, D. and Martinez, S. (2001). Neuroepithelial co-expression of Gbx2 and Otx2 precedes Fgf8 expression in the isthmic organizer. Mech. Dev. 101, 111-118.
    • (2001) Mech. Dev. , vol.101 , pp. 111-118
    • Garda, A.L.1    Echevarria, D.2    Martinez, S.3
  • 18
    • 0029059790 scopus 로고
    • Rescue of the En-1 mutant phenotype by replacement of En-1 with En-2
    • Hanks, M., Wurst, W., Anson-Cartwright, L., Auerbach, A. B. and Joyner, A. L. (1995). Rescue of the En-1 mutant phenotype by replacement of En-1 with En-2. Science 269, 679-682.
    • (1995) Science , vol.269 , pp. 679-682
    • Hanks, M.1    Wurst, W.2    Anson-Cartwright, L.3    Auerbach, A.B.4    Joyner, A.L.5
  • 19
    • 0033959238 scopus 로고    scopus 로고
    • Signalling by FGF8 from the isthmus patterns anterior hindbrain and establishes the anterior limit of Hox gene expression
    • Irving, C. and Mason, I. (2000). Signalling by FGF8 from the isthmus patterns anterior hindbrain and establishes the anterior limit of Hox gene expression. Development 127, 177-186.
    • (2000) Development , vol.127 , pp. 177-186
    • Irving, C.1    Mason, I.2
  • 20
    • 0019958819 scopus 로고
    • Cephalic neurulation in the mouse embryo analyzed by SEM and morphometry
    • Jacobson, A. G. and Tam, P. P. (1982). Cephalic neurulation in the mouse embryo analyzed by SEM and morphometry. Anat. Rec. 203, 375-396.
    • (1982) Anat. Rec. , vol.203 , pp. 375-396
    • Jacobson, A.G.1    Tam, P.P.2
  • 21
    • 0030069671 scopus 로고    scopus 로고
    • Engrailed, Wnt and Pax genes regulate midbrain-hindbrain development
    • Joyner, A. L. (1996). Engrailed, Wnt and Pax genes regulate midbrain-hindbrain development. Trends Genet. 12, 15-20.
    • (1996) Trends Genet. , vol.12 , pp. 15-20
    • Joyner, A.L.1
  • 22
    • 0034214414 scopus 로고    scopus 로고
    • Two lineage boundaries coordinate vertebrate apical ectodermal ridge formation
    • Kimmel, R. A., Turnbull, D. H., Blanquet, V., Wurst, W., Loomis, C. A. and Joyner, A. L. (2000). Two lineage boundaries coordinate vertebrate apical ectodermal ridge formation. Genes Dev. 14, 1377-1389.
    • (2000) Genes Dev. , vol.14 , pp. 1377-1389
    • Kimmel, R.A.1    Turnbull, D.H.2    Blanquet, V.3    Wurst, W.4    Loomis, C.A.5    Joyner, A.L.6
  • 23
    • 0028385705 scopus 로고
    • Reciprocal connections between the rabbit suprageniculate pretectal nucleus and the superior colliculus: Tracer study with horseradish peroxidase and fluorogold
    • Lagares, C., Caballero-Bleda, M., Fernandez, B. and Puelles, L. (1994). Reciprocal connections between the rabbit suprageniculate pretectal nucleus and the superior colliculus: tracer study with horseradish peroxidase and fluorogold. Vis. Neurosci. 11, 347-353.
    • (1994) Vis. Neurosci. , vol.11 , pp. 347-353
    • Lagares, C.1    Caballero-Bleda, M.2    Fernandez, B.3    Puelles, L.4
  • 24
    • 0030933498 scopus 로고    scopus 로고
    • Evidence that FGF8 signalling from the midbrain-hindbrain junction regulates growth and polarity in the developing midbrain
    • Lee, S. M., Danielian, P. S., Fritzsch, B. and McMahon, A. P. (1997). Evidence that FGF8 signalling from the midbrain-hindbrain junction regulates growth and polarity in the developing midbrain. Development 124, 959-969.
    • (1997) Development , vol.124 , pp. 959-969
    • Lee, S.M.1    Danielian, P.S.2    Fritzsch, B.3    McMahon, A.P.4
  • 25
    • 0033673531 scopus 로고    scopus 로고
    • Fgf8 signalling from the AER is essential for normal limb development
    • Lewandoski, M., Sun, X. and Martin, G. R. (2000). Fgf8 signalling from the AER is essential for normal limb development. Nat. Genet. 26, 460-463.
    • (2000) Nat. Genet. , vol.26 , pp. 460-463
    • Lewandoski, M.1    Sun, X.2    Martin, G.R.3
  • 26
    • 0035692010 scopus 로고    scopus 로고
    • Otx2 and Gbx2 are required for refinement and not induction of mid- hindbrain gene expression
    • Li, J. Y. and Joyner, A. L. (2001). Otx2 and Gbx2 are required for refinement and not induction of mid- hindbrain gene expression. Development 128, 4979-4991.
    • (2001) Development , vol.128 , pp. 4979-4991
    • Li, J.Y.1    Joyner, A.L.2
  • 27
    • 0037179758 scopus 로고    scopus 로고
    • Changing requirements for Gbx2 in development of the cerebellum and maintenance of the mid/hindbrain organizer
    • Li, J. Y. H., Lao, Z. and Joyner, A. L. (2002). Changing requirements for Gbx2 in development of the cerebellum and maintenance of the mid/hindbrain organizer. Neuron 36, 31-43.
    • (2002) Neuron , vol.36 , pp. 31-43
    • Li, J.Y.H.1    Lao, Z.2    Joyner, A.L.3
  • 28
    • 0034925298 scopus 로고    scopus 로고
    • Early anterior/posterior patterning of the midbrain and cerebellum
    • Liu, A. and Joyner, A. L. (2001a). Early anterior/posterior patterning of the midbrain and cerebellum. Annu. Rev. Neurosci. 24, 869-896.
    • (2001) Annu. Rev. Neurosci. , vol.24 , pp. 869-896
    • Liu, A.1    Joyner, A.L.2
  • 29
    • 0035141207 scopus 로고    scopus 로고
    • EN and GBX2 play essential roles downstream of FGF8 in patterning the mouse mid/hindbrain region
    • Liu, A. and Joyner, A. L. (2001b). EN and GBX2 play essential roles downstream of FGF8 in patterning the mouse mid/hindbrain region. Development 128, 181-191.
    • (2001) Development , vol.128 , pp. 181-191
    • Liu, A.1    Joyner, A.L.2
  • 30
    • 0032708854 scopus 로고    scopus 로고
    • FGF8 can activate Gbx2 and transform regions of the rostral mouse brain into a hindbrain fate
    • Liu, A., Losos, K. and Joyner, A. L. (1999). FGF8 can activate Gbx2 and transform regions of the rostral mouse brain into a hindbrain fate. Development 126, 4827-4838.
    • (1999) Development , vol.126 , pp. 4827-4838
    • Liu, A.1    Losos, K.2    Joyner, A.L.3
  • 31
    • 0036203355 scopus 로고    scopus 로고
    • Coordination of chondrogenesis and osteogenesis by fibroblast growth factor 18
    • Liu, Z., Xu, J., Colvin, J. S. and Ornitz, D. M. (2002). Coordination of chondrogenesis and osteogenesis by fibroblast growth factor 18. Genes Dev. 16, 859-869.
    • (2002) Genes Dev. , vol.16 , pp. 859-869
    • Liu, Z.1    Xu, J.2    Colvin, J.S.3    Ornitz, D.M.4
  • 32
    • 0027475752 scopus 로고
    • Two enhancer regions in the mouse En-2 locus direct expression to the mid/hindbrain region and mandibular myoblasts
    • Logan, C., Khoo, W. K., Cado, D. and Joyner, A. L. (1993). Two enhancer regions in the mouse En-2 locus direct expression to the mid/hindbrain region and mandibular myoblasts. Development 117, 905-916.
    • (1993) Development , vol.117 , pp. 905-916
    • Logan, C.1    Khoo, W.K.2    Cado, D.3    Joyner, A.L.4
  • 33
    • 0031667842 scopus 로고    scopus 로고
    • A series of no isthmus (noi) alleles of the zebrafish pax2.1 gene reveals multiple signaling events in development of the midbrain- hindbrain boundary
    • Lun, K. and Brand, M. (1998). A series of no isthmus (noi) alleles of the zebrafish pax2.1 gene reveals multiple signaling events in development of the midbrain- hindbrain boundary. Development 125, 3049-3062.
    • (1998) Development , vol.125 , pp. 3049-3062
    • Lun, K.1    Brand, M.2
  • 34
    • 0035069878 scopus 로고    scopus 로고
    • The isthmic organizer and brain regionalization
    • Martinez, S. (2001). The isthmic organizer and brain regionalization. Int. J. Dev. Biol. 45, 367-371.
    • (2001) Int. J. Dev. Biol. , vol.45 , pp. 367-371
    • Martinez, S.1
  • 35
    • 0032908043 scopus 로고    scopus 로고
    • FGF8 induces formation of an ectopic isthmic organizer and isthmocerebellar development via a repressive effect on Otx2 expression
    • Martinez, S., Crossley, P. H., Cobos, I., Rubenstein, J. L. and Martin, G. R. (1999). FGF8 induces formation of an ectopic isthmic organizer and isthmocerebellar development via a repressive effect on Otx2 expression. Development 126, 1189-1200.
    • (1999) Development , vol.126 , pp. 1189-1200
    • Martinez, S.1    Crossley, P.H.2    Cobos, I.3    Rubenstein, J.L.4    Martin, G.R.5
  • 36
    • 0035207512 scopus 로고    scopus 로고
    • Regionalisation of anterior neuroectoderm and its competence in responding to forebrain and midbrain inducing activities depend on mutual antagonism between OTX2 and GBX2
    • Martinez-Barbera, J. P., Signore, M., Boyl, P. P., Puelles, E., Acampora, D., Gogoi, R., Schubert, F., Lumsden, A. and Simeone, A. (2001). Regionalisation of anterior neuroectoderm and its competence in responding to forebrain and midbrain inducing activities depend on mutual antagonism between OTX2 and GBX2. Development 128, 4789-4800.
    • (2001) Development , vol.128 , pp. 4789-4800
    • Martinez-Barbera, J.P.1    Signore, M.2    Boyl, P.P.3    Puelles, E.4    Acampora, D.5    Gogoi, R.6    Schubert, F.7    Lumsden, A.8    Simeone, A.9
  • 37
    • 0032104452 scopus 로고    scopus 로고
    • Comparison of the expression of three highly related genes, Fgf8, Fgf17 and Fgf18, in the mouse embryo
    • Maruoka, Y., Ohbayashi, N., Hoshikawa, M., Itoh, N., Hogan, B. M. and Furuta, Y. (1998). Comparison of the expression of three highly related genes, Fgf8, Fgf17 and Fgf18, in the mouse embryo. Mech. Dev. 74, 175-177.
    • (1998) Mech. Dev. , vol.74 , pp. 175-177
    • Maruoka, Y.1    Ohbayashi, N.2    Hoshikawa, M.3    Itoh, N.4    Hogan, B.M.5    Furuta, Y.6
  • 38
    • 0025188130 scopus 로고
    • The Wnt-1 (int-1) proto-oncogene is required for development of a large region of the mouse brain
    • McMahon, A. P. and Bradley, A. (1990). The Wnt-1 (int-1) proto-oncogene is required for development of a large region of the mouse brain. Cell 62, 1073-1085.
    • (1990) Cell , vol.62 , pp. 1073-1085
    • McMahon, A.P.1    Bradley, A.2
  • 39
    • 0026719855 scopus 로고
    • The midbrain-hindbrain phenotype of Wnt-1-/Wnt-1- mice results from stepwise deletion of engrailed-expressing cells by 9.5 days postcoitum
    • McMahon, A. P., Joyner, A. L., Bradley, A. and McMahon, J. A. (1992). The midbrain-hindbrain phenotype of Wnt-1-/Wnt-1- mice results from stepwise deletion of engrailed-expressing cells by 9.5 days postcoitum. Cell 69, 581-595.
    • (1992) Cell , vol.69 , pp. 581-595
    • McMahon, A.P.1    Joyner, A.L.2    Bradley, A.3    McMahon, J.A.4
  • 40
    • 0031916557 scopus 로고    scopus 로고
    • An Fgf8 mutant allelic series generated by Cre- and Flp-mediated recombination
    • Meyers, E. N., Lewandoski, M. and Martin, G. R. (1998). An Fgf8 mutant allelic series generated by Cre- and Flp-mediated recombination. Nat. Genet. 18, 136-141.
    • (1998) Nat. Genet. , vol.18 , pp. 136-141
    • Meyers, E.N.1    Lewandoski, M.2    Martin, G.R.3
  • 41
    • 0032719944 scopus 로고    scopus 로고
    • Vertebrate Sprouty genes are induced by FGF signaling and can cause chondrodysplasia when overexpressed
    • Minowada, G., Jarvis, L. A., Chi, C. L., Neubuser, A., Sun, X., Hacohen, N., Krasnow, M. A. and Martin, G. R. (1999). Vertebrate Sprouty genes are induced by FGF signaling and can cause chondrodysplasia when overexpressed. Development 126, 4465-4475.
    • (1999) Development , vol.126 , pp. 4465-4475
    • Minowada, G.1    Jarvis, L.A.2    Chi, C.L.3    Neubuser, A.4    Sun, X.5    Hacohen, N.6    Krasnow, M.A.7    Martin, G.R.8
  • 42
    • 0034109160 scopus 로고    scopus 로고
    • Normal limb development in conditional mutants of Fgf4
    • Moon, A. M., Boulet, A. M. and Capecchi, M. R. (2000). Normal limb development in conditional mutants of Fgf4. Development 127, 989-996.
    • (2000) Development , vol.127 , pp. 989-996
    • Moon, A.M.1    Boulet, A.M.2    Capecchi, M.R.3
  • 43
    • 0035060985 scopus 로고    scopus 로고
    • Regionalization of the optic tectum: Combinations of gene expression that define the tectum
    • Nakamura, H. (2001). Regionalization of the optic tectum: combinations of gene expression that define the tectum. Trends Neurosci. 24, 32-39.
    • (2001) Trends Neurosci. , vol.24 , pp. 32-39
    • Nakamura, H.1
  • 44
    • 0038028264 scopus 로고    scopus 로고
    • Antagonistic interactions between FGF and BMP signaling pathways: A mechanism for positioning the sites of tooth formation
    • Neubuser, A., Peters, H., Balling, R. and Martin, G. R. (1997). Antagonistic interactions between FGF and BMP signaling pathways: a mechanism for positioning the sites of tooth formation. Cell 90, 247-255.
    • (1997) Cell , vol.90 , pp. 247-255
    • Neubuser, A.1    Peters, H.2    Balling, R.3    Martin, G.R.4
  • 45
    • 0033199550 scopus 로고    scopus 로고
    • Identification of maxillary factor, a maxillary process-derived chemoattractant for developing trigeminal sensory axons
    • O'Connor, R. and Tessier-Lavigne, M. (1999). Identification of maxillary factor, a maxillary process-derived chemoattractant for developing trigeminal sensory axons. Neuron 24, 165-178.
    • (1999) Neuron , vol.24 , pp. 165-178
    • O'Connor, R.1    Tessier-Lavigne, M.2
  • 46
    • 0036205735 scopus 로고    scopus 로고
    • FGF18 is required for normal cell proliferation and differentiation during osteogenesis and chondrogenesis
    • Ohbayashi, N., Shibayama, M., Kurotaki, Y., Imanishi, M., Fujimori, T., Itoh, N. and Takada, S. (2002). FGF18 is required for normal cell proliferation and differentiation during osteogenesis and chondrogenesis. Genes Dev. 16, 870-879.
    • (2002) Genes Dev. , vol.16 , pp. 870-879
    • Ohbayashi, N.1    Shibayama, M.2    Kurotaki, Y.3    Imanishi, M.4    Fujimori, T.5    Itoh, N.6    Takada, S.7
  • 47
    • 0034234646 scopus 로고    scopus 로고
    • Involvement of fibroblast growth factor (FGF)18-FGF8 signaling in specification of left-right asymmetry and brain and limb development of the chick embryo
    • Ohuchi, H., Kimura, S., Watamoto, M. and Itoh, N. (2000). Involvement of fibroblast growth factor (FGF)18-FGF8 signaling in specification of left-right asymmetry and brain and limb development of the chick embryo. Mech. Dev. 95, 55-66.
    • (2000) Mech. Dev. , vol.95 , pp. 55-66
    • Ohuchi, H.1    Kimura, S.2    Watamoto, M.3    Itoh, N.4
  • 48
    • 0027201903 scopus 로고
    • Mouse Wnt genes exhibit discrete domains of expression in the early embryonic CNS and limb buds
    • Parr, B. A., Shea, M. J., Vassileva, G. and McMahon, A. P. (1993). Mouse Wnt genes exhibit discrete domains of expression in the early embryonic CNS and limb buds. Development 119, 247-261.
    • (1993) Development , vol.119 , pp. 247-261
    • Parr, B.A.1    Shea, M.J.2    Vassileva, G.3    McMahon, A.P.4
  • 49
    • 0034084768 scopus 로고    scopus 로고
    • Roles of Wnt proteins in neural development and maintenance
    • Patapoutian, A. and Reichardt, L. F. (2000). Roles of Wnt proteins in neural development and maintenance. Curr. Opin. Neurobiol. 10, 392-399.
    • (2000) Curr. Opin. Neurobiol. , vol.10 , pp. 392-399
    • Patapoutian, A.1    Reichardt, L.F.2
  • 50
    • 0000850705 scopus 로고    scopus 로고
    • The midbrain-hindbrain junction: A model system for brain regionalization through morphogenetic neuroepithelial interactions
    • (ed. P. Lonai), Amsterdam: Harwood Academic Publishers
    • Puelles, L., Marin, F., Martinez de la Torre, M. and Martinez, S. (1996). The midbrain-hindbrain junction: a model system for brain regionalization through morphogenetic neuroepithelial interactions. In Mammalian Development (ed. P. Lonai), pp. 173-197. Amsterdam: Harwood Academic Publishers.
    • (1996) Mammalian Development , pp. 173-197
    • Puelles, L.1    Marin, F.2    Martinez de la Torre, M.3    Martinez, S.4
  • 51
    • 0031926506 scopus 로고    scopus 로고
    • Fgf8 is mutated in zebrafish acerebellar (ace) mutants and is required for maintenance of midbrain-hindbrain boundary development and somitogenesis
    • Reifers, F., Bohli, H., Walsh, E. C., Crossley, P. H., Stainier, D. Y. and Brand, M. (1998). Fgf8 is mutated in zebrafish acerebellar (ace) mutants and is required for maintenance of midbrain-hindbrain boundary development and somitogenesis. Development 125, 2381-2395.
    • (1998) Development , vol.125 , pp. 2381-2395
    • Reifers, F.1    Bohli, H.2    Walsh, E.C.3    Crossley, P.H.4    Stainier, D.Y.5    Brand, M.6
  • 52
    • 0034919848 scopus 로고    scopus 로고
    • Inductive signal and tissue responsiveness defining the tectum and the cerebellum
    • Sato, T., Araki, I. and Nakamura, H. (2001). Inductive signal and tissue responsiveness defining the tectum and the cerebellum. Development 128, 2461-2469.
    • (2001) Development , vol.128 , pp. 2461-2469
    • Sato, T.1    Araki, I.2    Nakamura, H.3
  • 53
    • 0031461604 scopus 로고    scopus 로고
    • Conserved biological function between Pax-2 and Pax-5 in midbrain and cerebellum development: Evidence from targeted mutations
    • Schwarz, M., Alvarez-Bolado, G., Urbanek, P., Busslinger, M. and Gruss, P. (1997). Conserved biological function between Pax-2 and Pax-5 in midbrain and cerebellum development: evidence from targeted mutations. Proc. Natl. Acad. Sci. USA 94, 14518-14523.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 14518-14523
    • Schwarz, M.1    Alvarez-Bolado, G.2    Urbanek, P.3    Busslinger, M.4    Gruss, P.5
  • 54
    • 0029807669 scopus 로고    scopus 로고
    • Cell death in the CNS of the Wnt-1 mutant mouse
    • Serbedzija, G. N., Dickinson, M. and McMahon, A. P. (1996). Cell death in the CNS of the Wnt-1 mutant mouse. J. Neurobiol. 31, 275-282.
    • (1996) J. Neurobiol. , vol.31 , pp. 275-282
    • Serbedzija, G.N.1    Dickinson, M.2    McMahon, A.P.3
  • 55
    • 0033042805 scopus 로고    scopus 로고
    • Sequential roles for Fgf4, En1 and Fgf8 in specification and regionalisation of the midbrain
    • Shamim, H., Mahmood, R., Logan, C., Doherty, P., Lumsden, A. and Mason, I. (1999). Sequential roles for Fgf4, En1 and Fgf8 in specification and regionalisation of the midbrain. Development 126, 945-959.
    • (1999) Development , vol.126 , pp. 945-959
    • Shamim, H.1    Mahmood, R.2    Logan, C.3    Doherty, P.4    Lumsden, A.5    Mason, I.6
  • 56
    • 0034214298 scopus 로고    scopus 로고
    • Positioning the isthmic organizer where Otx2 and Gbx2meet
    • Simeone, A. (2000). Positioning the isthmic organizer where Otx2 and Gbx2meet. Trends Genet. 16, 237-240.
    • (2000) Trends Genet. , vol.16 , pp. 237-240
    • Simeone, A.1
  • 57
    • 0027260743 scopus 로고
    • A vertebrate gene related to orthodenticle contains a homeodomain of the bicoid class and demarcates anterior neuroectoderm in the gastrulating mouse embryo
    • Simeone, A., Acampora, D., Mallamaci, A., Stornaiuolo, A., D'Apice, M., Nigro, V. and Boncinelli, E. (1993). A vertebrate gene related to orthodenticle contains a homeodomain of the bicoid class and demarcates anterior neuroectoderm in the gastrulating mouse embryo. EMBO J. 12, 2735-2747.
    • (1993) EMBO J. , vol.12 , pp. 2735-2747
    • Simeone, A.1    Acampora, D.2    Mallamaci, A.3    Stornaiuolo, A.4    D'Apice, M.5    Nigro, V.6    Boncinelli, E.7
  • 58
    • 0032923739 scopus 로고    scopus 로고
    • Generalized lacZ expression with the ROSA26 Cre reporter strain
    • Soriano, P. (1999). Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat. Genet. 21, 70-71.
    • (1999) Nat. Genet. , vol.21 , pp. 70-71
    • Soriano, P.1
  • 59
    • 0037452624 scopus 로고    scopus 로고
    • Dosage of Fgf8 determines whether cell survival is positive or negatively regulated in the developing forebrain
    • Storm, E., Rubenstein, J. L. R. and Martin, G. R. (2003). Dosage of Fgf8 determines whether cell survival is positive or negatively regulated in the developing forebrain. Proc. Natl. Acad. Sci. USA 100, 1757-1762.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 1757-1762
    • Storm, E.1    Rubenstein, J.L.R.2    Martin, G.R.3
  • 60
    • 0036682468 scopus 로고    scopus 로고
    • Functions of FGF signalling from the apical ectodermal ridge in limb development
    • Sun, X., Mariani, F. V. and Martin, G. R. (2002). Functions of FGF signalling from the apical ectodermal ridge in limb development. Nature 418, 501-508.
    • (2002) Nature , vol.418 , pp. 501-508
    • Sun, X.1    Mariani, F.V.2    Martin, G.R.3
  • 61
    • 0033565746 scopus 로고    scopus 로고
    • Targeted disruption of Fgf8 causes failure of cell migration in the gastrulating mouse embryo
    • Sun, X., Meyers, E. N., Lewandoski, M. and Martin, G. R. (1999). Targeted disruption of Fgf8 causes failure of cell migration in the gastrulating mouse embryo. Genes Dev. 13, 1834-1846.
    • (1999) Genes Dev. , vol.13 , pp. 1834-1846
    • Sun, X.1    Meyers, E.N.2    Lewandoski, M.3    Martin, G.R.4
  • 62
    • 0022674861 scopus 로고
    • A study of the pattern of prospective somites in the presomitic mesoderm of mouse embryos
    • Tam, P. P. (1986). A study of the pattern of prospective somites in the presomitic mesoderm of mouse embryos. J. Embryol. Exp. Morphol. 92, 269-285.
    • (1986) J. Embryol. Exp. Morphol. , vol.92 , pp. 269-285
    • Tam, P.P.1
  • 63
    • 0025074908 scopus 로고
    • Targeted disruption of the murine int-1 proto-oncogene resulting in severe abnormalities in midbrain and cerebellar development
    • Thomas, K. R. and Capecchi, M. R. (1990). Targeted disruption of the murine int-1 proto-oncogene resulting in severe abnormalities in midbrain and cerebellar development. Nature 346, 847-850.
    • (1990) Nature , vol.346 , pp. 847-850
    • Thomas, K.R.1    Capecchi, M.R.2
  • 64
    • 0020560077 scopus 로고
    • The inhibitory effect of 5-bromodeoxyuridine on the programmed cell death in the chick limb
    • Tone, S., Kanaka, S. and Kato, Y. (1983). The inhibitory effect of 5-bromodeoxyuridine on the programmed cell death in the chick limb. Dev. Growth Differ. 25, 381-391.
    • (1983) Dev. Growth Differ. , vol.25 , pp. 381-391
    • Tone, S.1    Kanaka, S.2    Kato, Y.3
  • 65
    • 0033397681 scopus 로고    scopus 로고
    • Cre-mediated gene inactivation demonstrates that FGF8 is required for cell survival and patterning of the first branchial arch
    • Trumpp, A., Depew, M. J., Rubenstein, J. L., Bishop, J. M. and Martin, G. R. (1999). Cre-mediated gene inactivation demonstrates that FGF8 is required for cell survival and patterning of the first branchial arch. Genes Dev. 13, 3136-3148.
    • (1999) Genes Dev. , vol.13 , pp. 3136-3148
    • Trumpp, A.1    Depew, M.J.2    Rubenstein, J.L.3    Bishop, J.M.4    Martin, G.R.5
  • 66
    • 0030851192 scopus 로고    scopus 로고
    • Specification of the anterior hindbrain and establishment of a normal mid/hindbrain organizer is dependent on Gbx2 gene function
    • Wassarman, K. M., Lewandoski, M., Campbell, K., Joyner, A. L., Rubenstein, J. L., Martinez, S. and Martin, G. R. (1997). Specification of the anterior hindbrain and establishment of a normal mid/hindbrain organizer is dependent on Gbx2 gene function. Development 124, 2923-2934.
    • (1997) Development , vol.124 , pp. 2923-2934
    • Wassarman, K.M.1    Lewandoski, M.2    Campbell, K.3    Joyner, A.L.4    Rubenstein, J.L.5    Martinez, S.6    Martin, G.R.7
  • 67
    • 0031417066 scopus 로고    scopus 로고
    • Early mesencephalon/metencephalon patterning and development of the cerebellum
    • Wassef, M. and Joyner, A. L. (1997). Early mesencephalon/metencephalon patterning and development of the cerebellum. Perspect Dev. Neurobiol. 5, 3-16.
    • (1997) Perspect. Dev. Neurobiol. , vol.5 , pp. 3-16
    • Wassef, M.1    Joyner, A.L.2
  • 68
    • 0031127789 scopus 로고    scopus 로고
    • Is programmed cell death required for neural tube closure?
    • Weil, M., Jacobson, M. D. and Raff, M. C. (1997). Is programmed cell death required for neural tube closure? Curr. Biol. 7, 281-284.
    • (1997) Curr. Biol. , vol.7 , pp. 281-284
    • Weil, M.1    Jacobson, M.D.2    Raff, M.C.3
  • 69
    • 0024430616 scopus 로고
    • Segmental expression of Hox-2 homoeobox-containing genes in the developing mouse hindbrain
    • Wilkinson, D. G., Bhatt, S., Cook, M., Boncinelli, E. and Krumlauf, R. (1989). Segmental expression of Hox-2 homoeobox-containing genes in the developing mouse hindbrain. Nature 341, 405-409.
    • (1989) Nature , vol.341 , pp. 405-409
    • Wilkinson, D.G.1    Bhatt, S.2    Cook, M.3    Boncinelli, E.4    Krumlauf, R.5
  • 70
    • 0032739531 scopus 로고    scopus 로고
    • The role of the rhombic lip in avian cerebellum development
    • Wingate, R. J. and Hatten, M. E. (1999). The role of the rhombic lip in avian cerebellum development. Development 126, 4395-4404.
    • (1999) Development , vol.126 , pp. 4395-4404
    • Wingate, R.J.1    Hatten, M.E.2
  • 71
    • 0028310311 scopus 로고
    • Multiple developmental defects in Engrailed-1 mutant mice: An early mid- hindbrain deletion and patterning defects in forelimbs and sternum
    • Wurst, W., Auerbach, A. B. and Joyner, A. L. (1994). Multiple developmental defects in Engrailed-1 mutant mice: an early mid- hindbrain deletion and patterning defects in forelimbs and sternum. Development 120, 2065-2075.
    • (1994) Development , vol.120 , pp. 2065-2075
    • Wurst, W.1    Auerbach, A.B.2    Joyner, A.L.3
  • 72
    • 0035257203 scopus 로고    scopus 로고
    • Neural plate patterning: Upstream and downstream of the isthmic organizer
    • Wurst, W. and Bally-Cuif, L. (2001). Neural plate patterning: upstream and downstream of the isthmic organizer. Nat. Rev. Neurosci. 2, 99-108.
    • (2001) Nat. Rev. Neurosci. , vol.2 , pp. 99-108
    • Wurst, W.1    Bally-Cuif, L.2
  • 73
    • 0034023520 scopus 로고    scopus 로고
    • Temporal and spatial gradients of Fgf8 and Fgf17 regulate proliferation and differentiation of midline cerebellar structures
    • Xu, J., Liu, Z. and Ornitz, D. M. (2000). Temporal and spatial gradients of Fgf8 and Fgf17 regulate proliferation and differentiation of midline cerebellar structures. Development 127, 1833-1843.
    • (2000) Development , vol.127 , pp. 1833-1843
    • Xu, J.1    Liu, Z.2    Ornitz, D.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.