Downregulation of NANOG induces differentiation of human embryonic stem cells to extraembryonic lineages

Stem Cells

Volumn 23, Issue 8, 2005, Pages 1035-1043

  Hyslop, Louise ^a   Stojkovic, Miodrag ^a   Armstrong, Lyle ^a   Walter, Theresia ^a   Stojkovic, Petra ^a   Przyborski, Stefan ^b   Herbert, Mary ^a,c   Murdoch, Alison ^a,c   Strachan, Tom ^a   Lako, Majlinda ^a,c  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b DURHAM UNIVERSITY   (United Kingdom)

^c INSTITUTE OF HUMAN GENETICS   (United Kingdom)

Author keywords

Human embryonic stem cells; NANOG; Pluripotency; Primitive endoderm; Small interfering RNA; Trophectoderm

Indexed keywords

HOMEODOMAIN PROTEIN; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR NANOG; UNCLASSIFIED DRUG;

AFP GENE; ARTICLE; BLASTOCYST; CELL DIFFERENTIATION; CELL LINEAGE; CONTROLLED STUDY; ECTODERM; EMBRYO; EMBRYONAL CARCINOMA; EMBRYONIC STEM CELL; ENDODERM; GATA4 GENE; GATA6 GENE; GENE FUNCTION; GENE LOCATION; GENETIC ASSOCIATION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; INNER CELL MASS; LAMININ B1 GENE; NUCLEOTIDE SEQUENCE; PLURIPOTENT STEM CELL; QUANTITATIVE ASSAY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE;

ALPHA-FETOPROTEINS; BLASTOCYST; CELL DIFFERENTIATION; CELL LINE, TUMOR; CELL LINEAGE; DNA-BINDING PROTEINS; DOWN-REGULATION; EMBRYO; GATA4 TRANSCRIPTION FACTOR; GATA6 TRANSCRIPTION FACTOR; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GERM LAYERS; GREEN FLUORESCENT PROTEINS; HOMEODOMAIN PROTEINS; HUMANS; PLURIPOTENT STEM CELLS; RNA INTERFERENCE; RNA, MESSENGER; TRANSFECTION; TUMOR STEM CELLS;

MURINAE;

EID: 25444435417     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1634/stemcells.2005-0080     Document Type: Article

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