Sensitization of human bladder tumor cells to TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis with a small molecule IAP antagonist

Apoptosis

Volumn 16, Issue 1, 2011, Pages 13-26

  Griffith, Thomas S ^a   Kucaba, Tamara A ^a   O'Donnell, Michael A ^a   Burns, Jennifer ^b   Benetatos, Christopher ^b   McKinlay, Mark A ^b   Condon, Stephen ^b   Chunduru, Srinivas ^b  

^a UNIVERSITY OF IOWA   (United States)

^b TetraLogic Pharmaceuticals   (United States)

Author keywords

Bladder cancer; IAP; Smac mimetic; TRAIL

Indexed keywords

ANTINEOPLASTIC AGENT; INHIBITOR OF APOPTOSIS PROTEIN; RECOMBINANT TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; SMALL INTERFERING RNA; SMALL MOLECULE INHIBITOR OF APOPTOSIS PROTEIN ANTAGONIST; UNCLASSIFIED DRUG; X LINKED INHIBITOR OF APOPTOSIS;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BINDING AFFINITY; BLADDER CANCER; BLADDER TUMOR; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DRUG POTENTIATION; HUMAN; HUMAN TISSUE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; TUMOR CELL; TUMOR CELL LINE;

ANIMALS; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; APOPTOSIS; CASPASES; DRUG SYNERGISM; GENE EXPRESSION; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MITOCHONDRIAL PROTEINS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TNF-RELATED APOPTOSIS-INDUCING LIGAND; TUMOR CELLS, CULTURED; URINARY BLADDER NEOPLASMS; X-LINKED INHIBITOR OF APOPTOSIS PROTEIN;

EID: 79951556892     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-010-0535-3     Document Type: Article

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