Biochemical activity of reactive oxygen species scavengers do not predict retinal ganglion cell survival

Investigative Ophthalmology and Visual Science

Volumn 47, Issue 9, 2006, Pages 3878-3886

  Schlieve, Christopher R ^a   Lieven, Christopher J ^a   Levin, Leonard A ^a  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

21 [4 [2,6 BIS(1 PYRROLIDINYL) 4 PYRIMIDINYL] 1 PIPERAZINYL]PREGNA 1,4,9(11) TRIENE 3,20 DIONE; AMPLEX RED; CALCEIN; CALCEIN ACETOXYMETHYL ESTER; CATALASE; DEFEROXAMINE; HYDROETHIDINE; HYDROGEN PEROXIDE; HYDROXYL RADICAL; INDICATOR; POLYETHYLENEGLYCOL SUPEROXIDE DISMUTASE; PORPHYRIN DERIVATIVE; REACTIVE OXYGEN METABOLITE; SCAVENGER; SUPEROXIDE; TETRAKIS(1 METHYL 4 PYRIDYL)PORPHYRIN MANGANESE; TROLOX C; UNCLASSIFIED DRUG; 6-HYDROXY-2,5,7,8-TETRAMETHYLCHROMAN-2-CARBOXYLIC ACID; ANTIOXIDANT; CALCEIN AM; CHROMAN DERIVATIVE; FLUORESCEIN DERIVATIVE; MACROGOL DERIVATIVE; METALLOPORPHYRIN; MN(III) 5,10,15,20 TETRAKIS(N METHYLPYRIDINIUM 2 YL)PORPHYRIN; MN(III) 5,10,15,20-TETRAKIS(N-METHYLPYRIDINIUM-2-YL)PORPHYRIN; POLYETHYLENE GLYCOL SUPEROXIDE DISMUTASE; POLYETHYLENE GLYCOL-SUPEROXIDE DISMUTASE; PREGNANE DERIVATIVE; SUPEROXIDE DISMUTASE;

ACCURACY; ANIMAL CELL; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; AXONAL INJURY; CELL CULTURE; CELL DEATH; CELL FREE SYSTEM; CELL PROTECTION; CELL VIABILITY; CULTURE MEDIUM; MITOCHONDRION; NERVE CELL CULTURE; NEWBORN; NONHUMAN; OPTIC NERVE DISEASE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RETINA GANGLION CELL; RETINA INJURY; SCAVENGING SYSTEM; SIGNAL TRANSDUCTION; SYMPATHETIC NERVE CELL; CELL SURVIVAL; COCULTURE; COMPARATIVE STUDY; DRUG EFFECT; LONG EVANS RAT; METABOLISM; PATHOLOGY; RAT;

ANTIOXIDANTS; CELL SURVIVAL; CELL-FREE SYSTEM; CELLS, CULTURED; CHROMANS; COCULTURE TECHNIQUES; FLUORESCEINS; FREE RADICAL SCAVENGERS; HYDROGEN PEROXIDE; METALLOPORPHYRINS; POLYETHYLENE GLYCOLS; PREGNATRIENES; RATS; RATS, LONG-EVANS; REACTIVE OXYGEN SPECIES; RETINAL GANGLION CELLS; SUPEROXIDE DISMUTASE; SUPEROXIDES;

EID: 33749132997     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: 10.1167/iovs.05-1010     Document Type: Article

References (41)

1. Berkelaar M, Clarke DB, Wang YC, Bray GM, Aguayo AJ. Axotomy results in delayed death and apoptosis of retinal ganglion cells in adult rats. J Neurosci. 1994;14:4368-4374.
2. Garcia-Valenzuela E, Gorczyca W, Darzynkiewicz Z, Sharma SC. Apoptosis in adult retinal ganglion cells after axotomy. J Neurobiol. 1994;25:431-438.
3. Levin LA, Louhab A. Apoptosis of retinal ganglion cells in anterior ischemic optic neuropathy. Arch Ophthalmol. 1996;114:488-491.
4. Mittag TW, Danias J, Pohorenec G, et al. Retinal damage after 3 to 4 months of elevated intraocular pressure in a rat glaucoma model. Invest Ophthalmol Vis Sci. 2000;41:3451-3459.
5. Kerrigan LA, Zack DJ, Quigley HA, Smith SD, Pease ME. TUNEL-positive ganglion cells in human primary open-angle glaucoma. Arch Ophthalmol. 1997;115:1031-1035.
6. Quigley HA, Nickells RW, Kerrigan LA, Pease ME, Thibault DJ, Zack DJ. Retinal ganglion cell death in experimental glaucoma and after axotomy occurs by apoptosis. Invest Ophthalmol Vis Sci. 1995;36:774-786.
7. Schnitzer J, Scherer J. Microglial cell responses in the rabbit retina following transection of the optic nerve. J Comp Neurol. 1990;302:779-791.
8. Mansour-Robaey S, Clarke DB, Wang YC, Bray GM, Aguayo AJ. Effects of ocular injury and administration of brain-derived neurotrophic factor on survival and regrowth of axotomized retinal ganglion cells. Proc Natl Acad Sci USA. 1994;91:1632-1636.
9. Cui Q, Harvey AR. At least two mechanisms are involved in the death of retinal ganglion cells following target ablation in neonatal rats. J Neurosci. 1995;15:8143-8155.
10. Stys PK, Ransom BR, Waxman SG, Davis PK. Role of extracellular calcium in anoxic injury of mammalian central white matter. Proc Natl Acad Sci USA. 1990;87:4212-4216.
11. Kiryu-Seo S, Sasaki M, Yokohama H, et al. Damage-induced neuronal endopeptidase (DINE) is a unique metallopeptidase expressed in response to neuronal damage and activates superoxide scavengers. Proc Natl Acad Sci USA. 2000;97:4345-4350.
12. Kikuchi M, Tenneti L, Lipton SA. Role of p38 mitogen-activated protein kinase in axotomy-induced apoptosis of rat retinal ganglion cells. J Neurosci. 2000;20:5037-5044.
13. Kermer P, Klocker N, Labes M, Thomsen S, Srinivasan A, Bahr M. Activation of caspase-3 in axotomized rat retinal ganglion cells in vivo. FEBS Lett. 1999;453:361-364.
14. Lieven CJ, Vrabec JP, Levin LA. The effects of oxidative stress on mitochondrial transmembrane potential in retinal ganglion cells. Antioxid Redox Signal. 2003;5:641-646.
15. Geiger LK, Kortuem KR, Alexejun C, Levin LA. Reduced redox state allows prolonged survival of axotomized neonatal retinal ganglion cells. Neuroscience. 2002;109:635-642.
16. Valencia A, Moran J. Reactive oxygen species induce different cell death mechanisms in cultured neurons. Free Radic Biol Med. 2004;36:1112-1125.
17. Greenlund LJ, Deckwerth TL, Johnson EM. Superoxide dismutase delays neuronal apoptosis: a role for reactive oxygen species in programmed neuronal death. Neuron. 1995;14:303-315.
18. Kirkland RA, Franklin JL. Bax, reactive oxygen, and cytochrome c release in neuronal apoptosis. Antioxid Redox Signal. 2003;5:589-596.
19. Barres BA, Silverstein BE, Corey DP, Chun LL. Immunological, morphological, and electrophysiological variation among retinal ganglion cells purified by panning. Neuron. 1988;1:791-803.
20. Zhao H, Kalivendi S, Zhang H, et al. Superoxide reacts with hydroethidine but forms a fluorescent product that is distinctly different from ethidium: potential implications in intracellular fluorescence detection of superoxide. Free Radic Biol Med. 2003;34:1359-1368.
21. Papapostolou I, Patsoukis N, Georgiou CD. The fluorescence detection of superoxide radical using hydroethidine could be complicated by the presence of heme proteins. Anal Biochem. 2004;332:290-298.
22. Lieven CJ, Schlieve CR, Hoegger MJ, Levin LA. Retinal ganglion cell axotomy induces an increase in intracellular superoxide anion. Invest Ophthalmol Vis Sci. 2006;47:1477-1485.
23. Kortuem K, Geiger LK, Levin LA. Differential susceptibility of retinal ganglion cells to reactive oxygen species. Invest Ophthalmol Vis Sci. 2000;41:3176-3182.
24. Qi X, Lewin AS, Hauswirth WW, Guy J. Optic neuropathy induced by reductions in mitochondrial superoxide dismutase. Invest Ophthalmol Vis Sci. 2003;44:1088-1096.
25. Tezel G, Yang X. Caspase-independent component of retinal ganglion cell death, in vitro. Invest Ophthalmol Vis Sci. 2004;45:4049-4059.
26. Patel M, Day BJ, Crapo JD, Fridovich I, McNamara JO. Requirement for superoxide in excitotoxic cell death. Neuron. 1996;16:345-355.
27. Day BJ, Shawen S, Liochev SI, Crapo JD. A metalloporphyrin superoxide dismutase mimetic protects against paraquat-induced endothelial cell injury, in vitro. J Pharmacol Exp Tber. 1995;275:1227-1232.
28. Porras AG, Olson JS, Palmer G. The reaction of reduced xanthine oxidase with oxygen. Kinetics of peroxide and superoxide formation. J Biol Chem. 1981;256:9006-9103.
29. Nguyen SM, Alexejun CN, Levin LA. Amplification of a reactive oxygen species signal in axotomized retinal ganglion cells. Antioxid Redox Signal. 2003;5:629-634.
30. Kirkland RA, Windelborn JA, Kasprzak JM, Franklin JL. A Bax-induced pro-oxidant state is critical for cytochrome c release during programmed neuronal death. J Neurosci. 2002;22:6480-6490.
31. Levkovitch-Verbin H, Harris-Cerruti C, Groner Y, Wheeler LA, Schwartz M, Yoles E. RGC death in mice after optic nerve crush injury: oxidative stress and neuroprotection. Invest Ophthalmol Vis Sci. 2000;41:4169-4174.
32. Osakada F, Hashino A, Kume T, Katsuki H, Kaneko S, Akaike A. Alpha-tocotrienol provides the most potent neuroprotection among vitamin E analogs on cultured striatal neurons. Neuropharmacology. 2004;47:904-915.
33. McCarthy S, Somayajulu M, Sikorska M, Borowy-Borowski H, Pandey S. Paraquat induces oxidative stress and neuronal cell death: neuroprotection by water-soluble Coenzyme Q10. Toxicol Appl Pharmacol. 2004;201:21-31.
34. Gonzalez-Polo RA, Rodriguez-Martin A, Moran JM, Niso M, Soler G, Fuentes JM. Paraquat-induced apoptotic cell death in cerebellar granule cells. Brain Res. 2004;1011:170-176.
35. Park SY, Chang I, Kim JY, et al. Resistance of mitochondrial DNA-depleted cells against cell death: role of mitochondrial superoxide dismutase. J Biol Chem. 2004;279:7512-7520.
36. Shimada H, Hirai K, Simamura E, Pan J. Mitochondrial NADH-quinone oxidoreductase of the outer membrane is responsible for paraquat cytotoxicity in rat livers. Arch Biochem Biophys. 1998;351:75-81.
37. Hirai K, Ikeda K, Wang GY. Paraquat damage of rat liver mitochondria by superoxide production depends on extramitochondrial NADH. Toxicology. 1992;72:1-16.
38. Horwitz LD, Sherman NA, Kong Y, et al. Lipophilic siderophores of Mycobacterium tuberculosis prevent cardiac reperfusion injury. Proc Natl Acad Sci USA. 1998;95:5263-5268.
39. Langeveld CH, Jongenelen CA, Schepens E, Stoof JC, Bast A, Drukarch B. Cultured rat striatal and cortical astrocytes protect mesencephalic dopaminergic neurons against hydrogen peroxide toxicity independent of their effect on neuronal development. Neurosci Lett. 1995;192:13-16.
40. Drukarch B, Schepens E, Stoof JC, Langeveld CH, Van Muiswinkel FL. Astrocyte-enhanced neuronal survival is mediated by scavenging of extracellular reactive oxygen species. Free Radic Biol Med. 1998;25:217-220.
41. Lucius R, Sievers J. Postnatal retinal ganglion cells in vitro: protection against reactive oxygen species (ROS)-induced axonal degeneration by cocultured astrocytes. Brain Res. 1996;743:56-62.