Cyclic Nucleotide Specificity and Cross-Activation of Cyclic Nucleotide Receptors

Handbook of Cell Signaling, Second Edition

Volumn 2, Issue , 2009, Pages 1549-1554

  Shabb, John B ^a  

^a UNIVERSITY OF NORTH DAKOTA SCHOOL OF MEDICINE AND HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 79251492264     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-0-12-374145-5.00190-X     Document Type: Chapter

References (83)

1. JB Shabb and JD Corbin (1992) Cyclic nucleotide-binding domains in proteins having diverse functions. J Biol Chem 267 5723-5726.
2. H Rehmann, A Wittinghofer and JL Bos (2007) Capturing cyclic nucleotides in action, snapshots from crystallographic studies. Nat Rev Mol Cell Biol 8 63-73.
3. SO Døskeland, D Øgreid, R Ekanger, PA Sturm, JP Miller and RH Suva (1983) Mapping of the two intrachain cyclic nucleotide binding sites of adenosine cyclic 3′, 5′-phosphate dependent protein kinase I. Biochemistry 22 1094-1101.
4. D Øgreid, R Ekanger, RH Suva, JP Miller and SO Døskeland (1989) Comparison of the two classes of binding sites (A and B) of type I and type II cyclic-AMP-dependent protein kinases by using cyclic nucleotide analogs. Eur J Biochem 181 19-31.
5. JD Corbin, D Øgreid, JP Miller, RH Suva, B Jastorff and SO Døskeland (1986) Studies of cGMP analog specificity and function of the two intrasubunit binding sites of cGMP-dependent protein kinase. J Biol Chem 261 1208-1214.
6. IT Weber, JB Shabb and JD Corbin (1989) Predicted structures of the cGMP binding domains of the cGMP-dependent protein kinase: a key alanine/threonine difference in evolutionary divergence of cAMP and cGMP binding sites. Biochemistry 28 6122-6127.
7. JB Shabb, L Ng and JD Corbin (1990) One amino acid change produces a high affinity cGMP-binding site in cAMP-dependent protein kinase. J Biol Chem 265 16,031-16,034.
8. JB Shabb, BD Buzzeo, L Ng and JD Corbin (1991) Mutating protein kinase cAMP-binding sites into cGMP-binding sites. Mechanism of cGMP selectivity. J Biol Chem 266 24,320-24,326.
9. RB Reed, M Sandberg, T Jahnsen, SM Lohmann, SH Francis and JD Corbin (1997) Structural order of the slow and fast intrasubunit cGMP-binding sites of type Iα cGMP-dependent protein kinase. Adv Sec Mess Phosph Res 31 205-217.
10. RB Reed, M Sandberg, T Jahnsen, SM Lohmann, SH Francis and JD Corbin (1996) Fast and slow cyclic nucleotide-dissociation sites in cAMP-dependent protein kinase are transposed in type Iβ cGMP-dependent protein kinase. J Biol Chem 271 17,570-17,575.
11. MK Taylor and MD Uhler (2000) The amino-terminal cyclic nucleotide binding site of the type II cGMP-dependent protein kinase is essential for full cyclic nucleotide-dependent activation. J Biol Chem 275 28,053-28,062.
12. IT Weber, TA Steitz, J Bubis and SS Taylor (1987) Predicted structures of cAMP binding domains of type I and II regulatory subunits of cAMP-dependent protein kinase. Biochemistry 26 343-351.
13. Y Su, WR Dostmann, FW Herberg, K Durick, NH Xuong, L Ten Eyck, SS Taylor and KI Varughese (1995) Regulatory subunit of protein kinase A: structure of deletion mutant with cAMP binding domains. Science 269 807-813.
14. TC Diller, Madhusudan., NH Xuong and SS Taylor (2001) Molecular basis for regulatory subunit diversity in cAMP-dependent protein kinase: crystal structure of the type I Iβ?regulatory subunit. Structure 9 73-82.
15. IT Weber and TA Steitz (1987) Structure of a complex of catabolite gene activator protein and cyclic AMP refined at 2.5 A resolution. J Mol Biol 198 311-326.
16. H Rehmann, B Prakash, E Wolf, A Rueppel, J de Rooij, JL Bos and A Wittinghofer (2003) Structure and regulation of the cAMP-binding domains of Epac2. Nat Struct Biol 10 26-32.
17. WN Zagotta, NB Olivier, KD Black, EC Young, R Olson and E Gouaux (2003) Structural basis for modulation and agonist specificity of HCN pacemaker channels. Nature 425 200-205.
18. GM Clayton, WR Silverman, L Heginbotham and JH Morais-Cabral (2004) Structural basis of ligand activation in a cyclic nucleotide regulated potassium channel. Cell 119 615-627.
19. MA Kapphahn and JB Shabb (1997) Contribution of the carboxyl-terminal regional of the cAMP-dependent protein kinase type Iα regulatory subunit to cyclic nucleotide interactions. Arch Biochem Biophys 348 347-356.
20. W Landgraf, R Hullin, C Göbel and F Hofmann (1986) Phosphorylation of cGMP-dependent protein kinase increases the affinity for cAMP. Eur J Biochem 154 113-117.
21. JA Smith, SH Francis, KA Walsh, S Kumar and JD Corbin (1996) Autophosphorylation of the type Iβ?cGMP-dependent protein kinase increases basal catalytic activity and enhances allosteric activation by cGMP or cAMP. J Biol Chem 271 20,756-20,762.
22. SP Collins and MD Uhler (1999) Cyclic AMP- and cyclic GMP-dependent protein kinases differ in their regulation of cyclic AMP response element-dependent gene transcription. J Biol Chem 274 8391-8404.
23. Y Hou, J Lascola, NO Dulin, RD Ye and DD Browning (2003) Activation of cGMP-dependent protein kinase by protein kinase C. J Biol Chem 278 16,706-16,712.
24. SH Francis, BD Noblett, BW Todd, JN Wells and JD Corbin (1988) Relaxation of vascular and tracheal smooth muscle by cyclic nucleotide analogs that preferentially activate purified cGMP-dependent protein kinase. Mol Pharmacol 34 506-517.
25. S Gambaryan, J Geiger, UR Schwarz, E Butt, A Begonja, A Obergfell and U Walter (2004) Potent inhibition of human platelets by cGMP analogs independent of cGMP-dependent protein kinase. Blood 103 2593-2600.
26. M Burkardt, M Glazova, S Gambaryan, T Vollkommer, E Butt, B Bader, K Heermeier, TM Lincoln, U Walter and A Palmetshofer (2000) KT5823 inhibits cGMP-dependent protein kinase activity in vitro but not in intact human platelets and rat mesangial cells. J Biol Chem 275 33,536-33,541.
27. J Bain, H McLauchlan, M Elliott and P Cohen (2003) The specificities of protein kinase inhibitors: an update. Biochem J 371 199-204.
28. SP Davies, H Reddy, C Matilde and P Cohen (2000) Specificity and mechanism of action of some commonly used protein kinase inhibitors. Biochem J 351 95-105.
29. J Bain, L Plater, M Elliott, N Shpiro, J Hasties, H McLauchlan, I Klevernic, S Arthur, D Alessi and P Cohen (2007) The selectivity of protein kinase inhibitors; a further update. Biochem J 408 297-315.
30. A Smolenski, AM Burkhardt, M Eigenthaler, E Butt, S Gambaryan, SM Lohmann and U Walter (1998) Functional analysis of cGMP-dependent protein kinases I and II as mediators of NO/cGMP effects. N S Arch Pharmacol 358 134-139.
31. AL Zimmerman, G Yamanaka, F Eckstein and DA Baylor (1985) Interaction of hydrolysis-resistant analogs of cyclic GMP with the phosphodiesterase and light-sensitive channel of retinal rod outer segments. Proc Natl Acad Sci USA 82 8813-8817.
32. JY Wei, ED Cohen, HG Genieser and CJ Barnstable (1998) Substituted cGMP analogs can act as selective agonists of the rod photoreceptor cGMP-gated cation channel. J Mol Neurosci 10 53-64.
33. S Frings, JW Lynch and B Lindemann (1992) Properties of cyclic nucleotide-gated channels mediating olfactory transduction. Activation, selectivity, and blockage. J Gen Physiol 100 45-67.
34. RH Kramer and GR Tibbs (1996) Antagonists of cyclic nucleotide-gated channels and molecular mapping of their site of action. J Neurosci 16 1285-1293.
35. AE Christensen, F Selheim, J de Rooij, S Dremier, F Schwede, KK Dao, A Martinez, C Maenhaut, JL Bos, HG Genieser and SO Døskeland (2003) cAMP analog mapping of Epac1 and cAMP kinase. Discriminating analogs demonstrate that Epac and cAMP kinase act synergistically to promote PC-12 cell neurite extension. J Biol Chem 278 35,394-35,402.
36. H Rehmann, F Schwede, SO Døskeland, A Wittinghofer and JL Bos (2003) Ligand-mediated activation of the cAMP-responsive guanine nucleotide exchange factor Epac. J Biol Chem 278 38,548-38,556.
37. JM Enserink, AE Christensen, J de Rooij, M van Triest, F Schwede, HG Genieser, SO Døskeland, JL Blank and JL Bos (2002) A novel Epac-specific cAMP analogue demonstrates independent regulation of Rap1 and ERK. Nat Cell Biol 4 901-906.
38. H Jiang, JL Colbran, SH Francis and JD Corbin (1992) Direct evidence for cross-activation of cGMP-dependent protein kinase by cAMP in pig coronary arteries. J Biol Chem 267 1015-1019.
39. TL Cornwell and TM Lincoln (1989) Regulation of intracellular Ca2+ levels in cultured vascular smooth muscle cells. Reduction of Ca2+ by atriopeptin and 8-Br-cyclic GMP is mediated by cyclic GMP-dependent protein kinase. J Biol Chem 264 1146-1155.
40. TM Lincoln, TL Cornwell and AE Taylor (1990) cGMP-dependent protein kinase mediates the reduction of Ca2+ by cAMP in vascular smooth muscle cells. Am J Physiol 258 C399-C407.
41. KS Murthy and GM Makhlouf (1994) Interaction of cA-kinase and cG-kinase in mediating relaxation of dispersed smooth muscle cells. Am J Physiol Cell Physiol 268 C171-C180.
42. SN Dhanakoti, Y Gao, MQ Nguyen and U Raj (2000) Involvement of cGMP-dependent protein kinase in the relaxation of ovine pulmonary arteries to cGMP and cAMP. J Appl Physiol 88 1637-1642.
43. W Keung, PM Vanhoutte and RYK Man (2005) Acute impairment of contractile responses by 17β-estradiol is cAMP and protein kinase G dependent in vascular smooth muscle cells of the porcine coronary arteries. Br J Pharmacol 144 71-79.
44. H-L Xu, HM Wolde, V Gavrilyuk, VL Baughman and DA Pelligrino (2004) cAMP modulates cGMP-mediated cerebral arteriolar relaxation in vivo. Am J Physiol Heart Circ Physiol 287 H2501-H2509.
45. CW Leffler, AL Fedinec, H Parfenova and JH Jaggar (2005) Permissive contributions of NO and prostacyclin in CO-induced cerebrovascular dilation in piglets. Am J Physiol Heart Circ Physiol 289 H432-H438.
46. RE White, JP Kryman, AM El-Mowafy, G Han and GO Carrier (2000) cAMP-dependent vasodilators cross-activate the cGMP-dependent protein kinase to stimulate BKCa channel activity in coronary artery smooth muscle cells. Circ Res 86 897-905.
47. S Zhu, G Han and RE White (2002) PGE2 action in human coronary artery smooth muscle: role of potassium channels and signaling cross-talk. J Vasc Res 39 477-488.
48. SA Barman, S Zhu, G Han and RE White (2003) cAMP activates BKCa channels in pulmonary arterial smooth muscle via cGMP-dependent protein kinase. Am J Physiol Lung Cell Mol Physiol 284 L1004-L1011.
49. JO Burnette and RE White (2006) PGI2 opens potassium channels in retinal pericytes by cyclic AMP-stimulated cross-activation of PKG. Exp Eye Res 83 1359-1365.
50. SD Koh and KM Sanders (1996) Modulation of Ca2+ current in canine colonic myocytes by cyclic nucleotide-dependent mechanisms. Am J Physiol Cell Physiol 271 C794-C803.
51. T Ishikawa, JR Hume and KD Keef (1993) Regulation of Ca2+ channels by cAMP and cGMP in vascular smooth muscle cells. Circ Res 73 1128-1137.
52. B Ay, A Iyanoye, GC Sieck, YS Prakash and CM Pabelick (2006) Cyclic nucleotide regulation of store-operated Ca2+ influx in airway smooth muscle. Am J Physiol Lung Cell Mol Physiol 290 L278-L283.
53. P Komalavilas and TM Lincoln (1994) Phosphorylation of the inositol 1, 4, 5-trisphosphate receptor by cyclic GMP-dependent protein kinase. J Biol Chem 269 8701-8707.
54. KS Murthy and H Zhou (2003) Selective phosphorylation of the IP3R-I in vivo by cGMP-dependent protein kinase in smooth muscle. Am J Physiol Gastr L Physiol 284 G221-G230.
55. A Pfeifer, P Klatt, S Massberg, L Ny, M Sausbier, C Hirneiss, G-X Wang, M Korth, A Aszódi, K-E Andersson, F Krombach, A Mayerhofer, P Ruth, R Fässler and F Hofmann (1998) Defective smooth muscle regulation in cGMP kinase I-deficient mice. EMBO J 17 3045-3051.
56. M Sausbier, XB Zhou, C Beier, U Sausbier, D Wolpers, S Maget, C Martin, A Dietrich, AR Ressmeyer, H Renz, J Schlossman, F Hofmann, W Neuhuber, T Gudermann, S Uhlig, M Korth and P Ruth (2007) Reduced rather than enhanced cholinergic airway constriction in mice with ablation of the large conductance Ca2+-activated K+ channel. FASEB J 21 812-822.
57. TM Lincoln, X Wu, H Sellak, N Dey and C-S Choi (2006) Regulation of vascular smooth muscle cell phenotype by cyclic GMP and cyclic GMP-dependent protein kinase. Front Biosci 11 356-367.
58. TL Cornwell, E Arnold, NJ Boerth and TM Lincoln (1992) Inhibition of smooth muscle cell growth by nitric oxide and activation of cAMP-dependent protein kinase by cGMP. Am J Physiol 267 C1405-C1413.
59. MT Osinski, BH Rauch and K Schrör (2001) Antimitogenic actions of organic nitrates are potentiated by sildenafil and mediated via activation of protein kinase A. Mol Pharmacol 59 1044-1050.
60. T Aizawa, H Wei, JM Miano, J Abe, BC Berk and C Yan (2003) Role of phosphodiesterase 3 in NO/cGMP-mediated anti-inflammatory effects in vascular smooth muscle cells. Circ Res 93 406-413.
61. W Wolfsgruber, S Feil, S Brummer, O Kuppinger, F Hofmann and R Feil (2003) A proatherogenic role for cGMP-dependent protein kinase in vascular smooth muscle cells. Proc Natl Acad Sci USA 100 13,519-13,524.
62. R Feil, S Feil and F Hofmann (2005) A heretical view on the role of NO and cGMP in vascular proliferative diseases. Trends Mol Med 11 71-75.
63. M Sausbier, R Schubert, V Voigt, C Hirneiss, A Pfeifer, M Korth, T Kleppisch, P Ruth and F Hofmann (2000) Mechanisms of NO/cGMP-dependent vasorelaxation. Circ Res 87 825-830.
64. R Wörner, R Lukowski, F Hofmann and JW Wegener (2006) cGMP signals mainly through cAMP kinase in permeabilized murine aorta. Am J Physiol Heart Circ Physiol 292 H237-H244.
65. J Bonnevier, R Fässler, AP Somlyo, AV Somlyo and A Arner (2004) Modulation of Ca2+ sensitivity by cyclic nucleotides in smooth muscle from protein kinase G-deficient mice. J Biol Chem 279 5146-5151.
66. P Hedlund, A Aszódi, A Pfeifer, P Alm, F Hofmann, M Ahmad, R Fässler and KE Andersson (2000) Erectile disfunction in cyclic GMP-dependent kinase I-deficient mice. Proc Natl Acad Sci USA 97 2349-2354.
67. CG Stief, S Ückert, AJ Becker, W Harringer, MC Truss, WG Forssmann and U Jonas (2000) Effects of sildenafil on cAMP and cGMP levels in isolated human cavernous and cardiac tissue. Urology 55 146-150.
68. D Prieto, L Rivera, P Recio, JL Ruiz Rubio, M Hernández and A Garcia-Sacristán (2006) Role of nitric oxide in the relaxation elicited by sildenafil in penile resistance arteries. J Urol 175 1164-1170.
69. S Massberg, M Sausbier, P Klatt, M Bauer, A Pfeifer, W Siess, R Fässler, P Ruth, F Krombach and F Hofmann (1999) Increased adhesion and aggregation of platelets lacking cyclic guanosine 3′,5′-monophosphate kinase I. J Exp Med 189 1255-1263.
70. Z Li, J Ajdic, M Eigenthaler and X Du (2003) A predominant role for cAMP-dependent protein kinase in the cGMP-induced phosphorylation of vasodilator-stimulated phosphoprotein and platelet inhibition in humans. Blood 101 4423-4429.
71. DH Maurice and RJ Haslam (1990) Molecular basis of the synergistic inhibition of platelet function by nitrovasodilators and activators of adenylate cyclase: inhibition of cyclic AMP breakdown by cyclic GMP. Mol Pharmacol 37 671-681.
72. C Nolte, M Eigenthaler, K Horstrup, P Hönig-Liedl and U Walter (1994) Synergistic phosphorylation of the focal adhesion assoicated vasodilator-stimulated phosphoprotein in intact human platelets in response to cGMP- and cAMP-elevating platelet inhibitors. Biochem Pharmacol 48 1569-1575.
73. BO Jensen, F Selheim, SO Døskeland, ARL Gear and H Holmsen (2004) Protein kinase A mediates inhibition of the thrombin-induced platelet shape change by nitric oxide. Blood 104 2775-2782.
74. B Sun, H Li, Y Shakur, J Hensley, S Hockman, J Kambayashi, VC Manganiello and Y Liu (2007) Role of phosphodiesterase type 3A and 3B in regulating platelet and cardiac function using subtype-selective knockout mice. Cell Signal 19 1765-1771.
75. LR Forte, PK Thorne, SL Eber, WJ Krause, RH Freeman, SH Francis and JD Corbin (1992) Stimulation of intestinal Cl− transport by heat-stable enterotoxin: activation of cAMP-dependent protein kinase by cGMP. Am J Physiol Cell Physiol 263 C607-C615.
76. AC Chao, FJ de Sauvage, YJ Dong, JA Wagner, DV Goeddel and P Gardner (1994) Activation of intestinal CFTR Cl− channel by heat-stable enterotoxin and guanylin via cAMP-dependent protein kinase. EMBO J 13 1065-1072.
77. XY Tien, TA Brasitus, MA Kaetzel, JR Dedman and DJ Nelson (1994) Activation of the cystic fibrosis transmembrane conductance regulator by cGMP in the human colonic cancer cell line Caco-2. J Biol Chem 269 51-54.
78. A Pfeifer, A Aszódi, U Seidler, P Ruth, F Hofmann and R Fässler (1996) Intestinal secretory defects and dwarfism in mice lacking cGMP-dependent protein kinase II. Science 274 2082-2086.
79. J Li, S Yang and TR Billiar (2000) Cyclic nucleotides suppress tumor necrosis factor α-mediated apoptosis by inhibiting caspase activation and cytochrome c release in primary hepatocytes via a mechanism independent of Akt activation. J Biol Chem 275 13,026-13,034.
80. KA Cullen, J McCool, MS Anwer and CRL Webster (2004) Activation of cAMP-guanine exchange factor confers PKA-independent protection from hepatocyte apoptosis. Am J Physiol Gastrointest Liver Physiol 287 G334-G343.
81. U Müller (2000) Prolonged activation of cAMP-dependent protein kinase during conditioning induces long-term memory in honeybees. Neuron 27 159-168.
82. G Leboulle and U Muller (2004) Synergistic activation of insect cAMP-dependent protein kinase A (type II) by cyclic AMP and cyclic GMP. FEBS Letts 576 216-220.
83. Y Matsumoto, S Unoki, H Aonuma and M Mizunami (2006) Critical role of nitric oxide-cGMP cascade in the formation of cAMP-dependent long-term memory. Learn Mem 13 35-44.