Activation of cAMP-guanine exchange factor confers PKA-independent protection from hepatocyte apoptosis

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 287, Issue 2 50-2, 2004, Pages

  Cullen, Kimberly A ^a   McCool, John ^a   Sawkat Anwer, M ^a   Webster, Cynthia R L ^a  

^a TUFTS UNIVERSITY   (United States)

Author keywords

Akt; Bile acid apoptosis; Death receptor apoptosis; Phosphatidylinositol 3 kinase; Rap 1

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; 8 (4 CHLOROPHENYLTHIO) 2' O METHYL CYCLIC AMP; 8 (4 CHLOROPHENYLTHIO) CYCLIC AMP; APOPTOSIS INHIBITOR; BILE ACID; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; FAS LIGAND; GLUCAGON; GUANINE NUCLEOTIDE EXCHANGE FACTOR; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; WORTMANNIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL ACTIVATION; CELL PROTECTION; CELL SURVIVAL; CELL TYPE; CONTROLLED STUDY; DOWNSTREAM PROCESSING; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; INHIBITION KINETICS; LIGAND BINDING; LIVER CELL; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; APOPTOSIS; BILE ACIDS AND SALTS; CELLS, CULTURED; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; CYTOPROTECTION; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HEPATOCYTES; MALE; MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RAP1 GTP-BINDING PROTEINS; RATS; RATS, WISTAR; THIONUCLEOTIDES;

EID: 3242656381     PISSN: 01931857     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpgi.00517.2003     Document Type: Article

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