Structural basis of ligand activation in a cyclic nucleotide regulated potassium channel

Cell

Volumn 119, Issue 5, 2004, Pages 615-627

  Clayton, Gina M ^a   Silverman, William R ^a   Heginbotham, Lise ^a   Morais Cabral, João H ^a  

^a YALE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP; CYCLIC NUCLEOTIDE; DIMER; POTASSIUM CHANNEL;

ARTICLE; BACTERIUM; CONTROLLED STUDY; LIGAND BINDING; MESORHIZOBIUM LOTI; NONHUMAN; NUCLEOTIDE BINDING SITE; PRIORITY JOURNAL; REGULATORY MECHANISM;

BACTERIA (MICROORGANISMS); MESORHIZOBIUM; MESORHIZOBIUM LOTI;

EID: 8844263765     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cell.2004.10.030     Document Type: Article

References (36)

1. Anand G.S., Hughes C.A., Jones J.M., Taylor S.S., Komives E.A. Amide H/2H exchange reveals communication between the cAMP and catalytic subunit-binding sites in the R(I)alpha subunit of protein kinase A. J. Mol. Biol. 323:2002;377-386
2. Bacon D.J., Anderson W.F. A fast logarithm for rendering space-filling molecule pictures. J. Mol. Graph. 6:1991;219-220
3. Biel M., Schneider A., Wahl C. Cardiac HCN channels. structure, function, and modulation Trends Cardiovasc. Med. 12:2002;206-212
4. Brunger A.T., Adams P.D., Clore G.M., DeLano W.L., Gros P., Grosse-Kunstleve R.W., Jiang J.S., Kuszewski J., Nilges M., Pannu N.S., et al. Crystallography & NMR system. a new software suite for macromolecular structure determination Acta Crystallogr. D Biol. Crystallogr. 54:1998;905-921
5. Collaborative Computational Project Number 4 The CCP4 suite. programs for protein crystallography Acta. Crystallogr. D. Biol. Crystallogr. 50:1994;760-763
6. Dani V.S., Ramakrishnan C., Varadarajan R. MODIP revisited. re-evaluation and refinement of an automated procedure for modeling of disulfide bonds in proteins Protein Eng. 16:2003;187-193
7. Diller T.C., Madhusudan, Xuong N.H., Taylor S.S. Molecular basis for regulatory subunit diversity in cAMP-dependent protein kinase. crystal structure of the type II beta regulatory subunit Structure (Camb.). 9:2001;73-82
8. Doyle D.A., Morais-Cabral J., Pfuetzner R.A., Kuo A., Gulbis J.M., Cohen S.L., Chait B.T., MacKinnon R. The structure of the potassium channel. molecular basis of K+ conduction and selectivity Science. 280:1998;69-77
9. Flynn G.E., Johnson J.P. Jr., Zagotta W.N. Cyclic nucleotide-gated channels. shedding light on the opening of a channel pore Nat. Rev. Neurosci. 2:2001;643-651
10. Gordon S.E., Varnum M.D., Zagotta W.N. Direct interaction between amino- and carboxyl-terminal domains of cyclic nucleotide-gated channels. Neuron. 19:1997;431-441
11. Heginbotham L., Kolmakova-Partensky L., Miller C. Functional reconstitution of a prokaryotic K+ channel. J. Gen. Physiol. 111:1998;741-750
12. Heginbotham L., LeMasurier M., Kolmakova-Partensky L., Miller C. Single streptomyces lividans K(+) channels. functional asymmetries and sidedness of proton activation J. Gen. Physiol. 114:1999;551-560
13. Hille, B. (2001). Ion Channels of Excitable Membranes, Third Edition (Sunderland, MA: Sinauer Associates).
14. Jiang Y., Lee A., Chen J., Cadene M., Chait B.T., MacKinnon R. Crystal structure and mechanism of a calcium-gated potassium channel. Nature. 417:2002;515-522. a
15. Jiang Y., Lee A., Chen J., Cadene M., Chait B.T., MacKinnon R. The open pore conformation of potassium channels. Nature. 417:2002;523-526. b
16. Jones T.A., Zou J.Y., Cowan S.W., Kjeldgaard Improved methods for building protein models in electron density maps and the location of errors in these models. Acta Crystallogr. A. 47:1991;110-119
17. Kaupp U.B., Seifert R. Cyclic nucleotide-gated ion channels. Physiol. Rev. 82:2002;769-824
18. Laemmli U.K. Nature. 227:1970;680-685
19. Liu D.T., Tibbs G.R., Paoletti P., Siegelbaum S.A. Constraining ligand-binding site stoichiometry suggests that a cyclic nucleotide-gated channel is composed of two functional dimers. Neuron. 21:1998;235-248
20. MacKinnon R. Potassium channels. FEBS Lett. 555:2003;62-65
21. Maduke M., Pheasant D.J., Miller C. High-level expression, functional reconstitution, and quaternary structure of a prokaryotic ClC-type chloride channel. J. Gen. Physiol. 114:1999;713-722
22. Matulef K., Zagotta W. Multimerization of the ligand binding domains of cyclic nucleotide-gated channels. Neuron. 36:2002;93-103
23. Matulef K., Zagotta W.N. Cyclic nucleotide-gated ion channels. Annu. Rev. Cell Dev. Biol. 19:2003;23-44
24. Nimigean C.M., Shane T., Miller C. A cyclic nucleotide modulated prokaryotic K+ channel. J. Gen. Physiol. 124:2004;203-210
25. Passner J.M., Schultz S.C., Steitz T.A. Modeling the cAMP-induced allosteric transition using the crystal structure of CAP-cAMP at 2.1 Å resolution. J. Mol. Biol. 304:2000;847-859
26. Rehmann H., Prakash B., Wolf E., Rueppel A., De Rooij J., Bos J.L., Wittinghofer A. Structure and regulation of the cAMP-binding domains of Epac2. Nat. Struct. Biol. 10:2003;26-32
27. Schmidt T.G., Skerra A. The random peptide library-assisted engineering of a C-terminal affinity peptide, useful for the detection and purification of a functional Ig Fv fragment. Protein Eng. 6:1993;109-122
28. Su Y., Dostmann W.R., Herberg F.W., Durick K., Xuong N.H., Ten Eyck L., Taylor S.S., Varughese K.I. Regulatory subunit of protein kinase A. structure of deletion mutant with cAMP binding domains Science. 269:1995;807-813
29. Sun Y., Olson R., Horning M., Armstrong N., Mayer M., Gouaux E. Mechanism of glutamate receptor desensitization. Nature. 417:2002;245-253
30. Terwilliger T.C. Reciprocal-space solvent flattening. Acta Crystallogr. D Biol. Crystallogr. 55:1999;1863-1871
31. Terwilliger T.C., Berendzen J. Automated MAD and MIR structure solution. Acta Crystallogr. D Biol. Crystallogr. 55:1999;849-861
32. Weber I.T., Steitz T.A. Structure of a complex of catabolite gene activator protein and cyclic AMP refined at 2.5 Å resolution. J. Mol. Biol. 198:1987;311-326
33. Wu J., Brown S., Xuong N.H., Taylor S.S. RIalpha subunit of PKA. a cAMP-free structure reveals a hydrophobic capping mechanism for docking cAMP into site B Structure (Camb.). 12:2004;1057-1065
34. Yellen G. The moving parts of voltage-gated ion channels. Q. Rev. Biophys. 31:1998;239-295
35. Zagotta W.N., Olivier N.B., Black K.D., Young E.C., Olson R., Gouaux E. Structural basis for modulation and agonist specificity of HCN pacemaker channels. Nature. 425:2003;200-205
36. Zheng J., Zagotta W.N. Gating rearrangements in cyclic nucleotide-gated channels revealed by patch-clamp fluorometry. Neuron. 28:2000;369-374