Reduced rather than enhanced cholinergic airway constriction in mice with ablation of the large conductance Ca2+-activated K+ channel

FASEB Journal

Volumn 21, Issue 3, 2007, Pages 812-822

  Sausbier, Matthias ^a   Zhou, Xiao Bo ^b   Beier, Caroline ^b   Sausbier, Ulrike ^a   Wolpers, Daniela ^a   Maget, Sylvi ^b   Martin, Christian ^c   Dietrich, Alexander ^d   Ressmeyer, Anna Rebekka ^c   Renz, Harald ^d   Schlossmann, Jens ^e   Hofmann, Franz ^e   Neuhuber, Winfried ^f   Gudermann, Thomas ^d   Uhlig, Stefan ^c,g   Korth, Michael ^b   Ruth, Peter ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^c RESEARCH CENTER BORSTEL   (Germany)

^d PHILIPPS UNIVERSITY MARBURG   (Germany)

^e TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^f UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^g RWTH AACHEN UNIVERSITY   (Germany)

Author keywords

Airway contractility; BK channel; Cholinergic agonists; Cyclic GMP PKG signaling; Knockout mice

Indexed keywords

BETA ADRENERGIC RECEPTOR; CARBACHOL; CYCLIC AMP; CYCLIC GMP; CYCLIC GMP DEPENDENT PROTEIN KINASE; ISOPRENALINE; LARGE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; METHACHOLINE;

AIRWAY CONSTRICTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY PLETHYSMOGRAPHY; BRONCHOSPASM; CHOLINERGIC ACTIVITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME INHIBITION; GENE DELETION; ISOLATED LUNG; LUNG PERFUSION; MEMBRANE DEPOLARIZATION; MEMBRANE STEADY POTENTIAL; MOUSE; MYOTONIA; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SMOOTH MUSCLE CONTRACTION; SMOOTH MUSCLE FIBER; TRACHEA; TRACHEA MUSCLE; UPREGULATION;

AIRWAY OBSTRUCTION; ANIMALS; CALCIUM CHANNELS, L-TYPE; CARBACHOL; HUMANS; LARGE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; MEMBRANE POTENTIALS; METHACHOLINE CHLORIDE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MUSCLE, SMOOTH; RECEPTORS, ADRENERGIC; TRACHEA;

MUS;

EID: 33847377665     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fj.06-7167com     Document Type: Article

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