cAMP analog mapping of Epac1 and cAMP kinase: Discriminating analogs demonstrate that Epac and cAMP kinase act synergistically to promote PC-12 cell neurite extension

Journal of Biological Chemistry

Volumn 278, Issue 37, 2003, Pages 35394-35402

  Christensen, Anne E ^a   Selheim, Frode ^a   De Rooij, Johan ^b   Dremier, Sarah ^c   Schwede, Frank ^d   Dao, Khanh K ^a   Martinez, Aurora ^a   Maenhaut, Carine ^c   Bos, Johannes L ^b   Genieser, H G ^d   Doskeland, Stein O ^a  

^a UNIVERSITY OF BERGEN   (Norway)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^c VRIJE UNIVERSITEIT BRUSSEL   (Belgium)

^d BIOLOG Life Science Institute   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; PROTEINS; SUBSTITUTION REACTIONS;

ANALOG MAPPING;

BIOCHEMISTRY;

8 (4 CHLOROPHENYLTHIO) 2' O METHYLADENOSINE 3',5' CYCLIC PHOSPHATE; 8 (4 CHLOROPHENYLTHIO) CYCLIC AMP; 8 BROMO CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DERIVATIVE; N6 BENZOYL CYCLIC AMP; PROTEIN EPAC1; PROTEIN KINASE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; BINDING AFFINITY; CELL STRAIN; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME BINDING; ENZYME INHIBITION; ENZYME MECHANISM; ENZYME STRUCTURE; NERVE FIBER GROWTH; NONHUMAN; PEPTIDE MAPPING; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; RAT;

CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; CYCLIC GMP; ENZYME ACTIVATION; GUANINE NUCLEOTIDE EXCHANGE FACTORS; KINETICS; MODELS, MOLECULAR; PEPTIDE FRAGMENTS; PROTEIN CONFORMATION; RECOMBINANT FUSION PROTEINS; SUBSTRATE SPECIFICITY;

ANIMALIA;

EID: 0041315574     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M302179200     Document Type: Article

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