Substituted cGMP analogs can act as selective agonists of the rod photoreceptor cGMP-gated cation channel

Journal of Molecular Neuroscience

Volumn 10, Issue 1, 1998, Pages 53-64

  Wei, Ji Ye ^a   Cohen, Ethan D ^a   Genieser, Hans G ^b   Barnstable, Colin J ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Research Laboratory and Biochemicals   (Germany)

Author keywords

Agonists; Antagonists; cGMP binding domain of cGMP gated channel; cGMP dependent protein kinase; cGMP gated cation channel; Cloned rat rod cGMP gated channel subunit; Patch clamp studies; Xenopus oocytes expression

Indexed keywords

CATION CHANNEL; CYCLIC GMP; CYCLIC GMP DEPENDENT PROTEIN KINASE; CYCLIC GMP DERIVATIVE;

ARTICLE; CHANNEL GATING; MEMBRANE PERMEABILITY; PATCH CLAMP; PHOTORECEPTOR; RETINA ROD;

EID: 0031866825     PISSN: 08958696     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02737085     Document Type: Article

References (52)

1. Ahmad I., Redmond L. J., and Barnstable C. J. (1990) Developmental and tissue-specific expression of the rod photoreceptor cGMP-gated ion channel gene. Biochem. Biophys. Res. Commun. 173, 463-470.
2. Ahmad I., Korbmacher C., Segal A. S., Cheung P., Boulpaep E. L., and Barnstable C. J. (1992) Mouse cortical collecting duct cells show nonselective cation channel activity and express a gene related to the cGMP-gated rod photoreceptor channel. Proc. Natl. Acad. Sci. USA 89, 10,262-10,266.
3. Ahmad I., Leinders-Zufall T., Kocsis J. D., Shepherd G. M., Zufall F., and Barnstable C. J. (1994) Retinal ganglion cells express a cGMP-gated cation conductance activatable by nitric oxide donors. Neuron 12, 155-165.
4. Arancio O., Kandel E. R., and Hawkins R. D. (1995) Activity-dependent long-term enhancement of transmitter release by presynaptic 3′,5′-cyclic GMP in cultured hippocampal neurons. Nature 376, 74-80.
5. Arancio O., Klebler M., Lee C. J., Lev-Ram V., Tsien, R. Y., Kandel E. R., Hawkins R. D. (1996) Nitric oxide acts directly in presynaptic neuron to produce long-term potentiation in cultured hippocampal neurons. Cell 87, 1025-1035.
6. Barnstable C. J. and Wei J.-Y. (1995) Isolation and characterization of the alpha-subunit of rod photoreceptor cGMP-gated cation channel. J. Mol. Neurosci. 6, 289-302.
7. Baumann A., Frings S., Godde M., Seifert R., and Kaupp U. B. (1994) Primary structure and functional expression of a Drosophila cyclic nucleotide-gated channel present in eyes and antennae. EMBO J. 13, 5040-5050.
8. Biel M., Zong X., and Hofmann F. (1995). Molecular diversity of cyclic nucleotide-gated cation channel. Arch. Pharmacol. 351, 1-10.
9. Bradley J., Zhang Y., Bakin R., Lester H. A., Ronnett G. V., and Zinn K. (1997) Functional expression of the heteromeric "olfactory" cyclic nucleotide-gated channel in the hippocampus: a potential effector of synaptic plasticity in brain neurons. J. Neurosci. 17, 1993-2005.
10. Brown R. L., Bert R. J., Evans F. E., and Karpen J. W. (1993) Activation of retinal rod cGMP-gated channels: what makes for effective 8-substitute derivative of cGMP? Biochemistry 32, 10,089-10,095.
11. Coburn C. M. and Bargmann C. I. (1996) A putative cyclic nucleotide-gated channel is required for sensory development and function in C. elegans. Neuron 17, 695-706.
12. DiFrancesco D. and Tortora P. (1991) Direct activation of cardiac pacemaker channels by intracellular cyclic AMP. Nature 351, 145-147.
13. Ding C., Potter E. D., Qiu W., Coon S. L., Levine M. A., and Guggino S. E. (1997) Cloning and widespread distribution of the rat rod-type cyclic nucleotide-gated cation channel. Am. J. Physiol. 272, C1335-1344.
14. Distler M., Biel M., Flockerzi V., and Hofmann F. (1994) Expression of cyclic nucleotide-gated cation channels in non-sensory tissues and cells. Neuropharmacology 33, 1275-1282.
15. Dryer S. E. and Henderson D. (1991) A cyclic GMP-activated channel in dissociated cells of the chick pineal gland. Nature. 353, 756-758.
16. Feng L., Subbaraya I., Yamamoto N., Baehr W., and Kraus-Friedmann N. (1996) Expression of photoreceptor cyclic nucleotide-gated channel a subunit (CNGCa) in the liver and skeletal muscle. FEBS Lett. 395, 77-81.
17. Finn J. T., Grunwald M. E., and Yau K. W. (1996) Cyclic nucleotide-gated ion channels: an extended family with diverse functions. Annu. Rev. Physiol. 58, 395-426.
18. Goulding E. H., Tibbs G. R., Liu D., and Siegelbaum S. A. (1993) Role of H5 domain in determining pore diameter and ion permeation through cyclic nucleotide-gated channels. Nature 364, 61-64.
19. Goulding E. H., Tibbs G. R., and Siegelbaum S. A. (1994) Molecular mechanism of cyclic nucleotide-gated channel activation. Nature 372, 369-374.
20. Guy H. R., Durell S. R., Warmke J., Drysdale R., and Ganetzky B. (1991) Similarities in amino acid sequences of Drosophila eng and cyclic nucleotide-gated channels. Science 254, 730.
21. Jan L. Y. and Jan Y. N. (1990) A superfamily of ion channels. Nature 345, 672.
22. Jan L. Y. and Jan Y. N. (1992) Tracing the roots of ion channels. Cell 69, 715-718.
23. 2+ desensitization of skinned rat artery. Eur. J. Pharmacol. 323, 75-82.
24. Kaupp U. B. (1995) Family of cyclic nucleotide gated ion channels. Current Opin. Neurobiol. 5, 434-442.
25. Kingston P. A., Zufall F., and Barnstable C. J. (1996) Rat hippocampal neurons express genes for both rod retinal and olfactory cyclic nucleotide-gated channels: novel targets for cAMP/ cGMP function. Proc. Natl. Acad. Sci. USA 93, 10,440-10,445.
26. Koch K.-W. and Kaupp U. B. (1985) Cyclic GMP directly regulates a cationic conductance in membranes of bovine rods by a cooperative mechanism. J. Biol. Chem. 260, 6788-6800.
27. Komatsu H., Mori I., Rhee J.-S., Akaike N., and Ohshima Y. (1996) Mutations in a cyclic nucleotide-gated channel lead to abnormal thermosensation and chemosensation in C. elegans. Neuron 17, 707-718.
28. Kramer R. H. and Tibbs G. R. (1996) Antagonists of cyclic nucleotide-gated channels and molecular mapping of their site of action. J. Neurosci. 16, 1285-1293.
29. Kumar V. D. and Weber I. T. (1992) Molecular model of the cyclic GMP-binding domain of cyclic GMP-gated ion channel Biochemistry 31, 4643-4649.
30. Leinders-Zufall T. and Zufall F. (1995) Block of cyclic nucleotide-gated channels in salamander olfactory receptor neurons by the guanylyl cyclase inhibitor LY83583. J. Neurophysiol. 74, 2759-2762.
31. Leinders-Zufall T., Rosenboom H., Barnstable C. J., Shepherd G. M., and Zufall F. (1995) A calcium-permeable cGMP-activated cation conductance in hippocampal neurons. Neuroreport 6, 1761-1765.
32. Liu D. T., Tibbs G. R., and Siegelbaum S. A. (1996) Subunit stoichiometry of cyclic nucleotide-gated channels and effects of subunit order on channel function. Neuron 16, 983-990.
33. Mckay D. B. and Steitz T. A. (1981) Structure of catabolite gene activator protein at 2.9Å resolution suggests binding to left-handed B-DNA. Nature 290, 744-749.
34. Misaka T., Kusabe Y., Emori Y., Gonoi T., Arai S., and Abe K. (1997) Taste buds have a cyclic nucleotide-activated channel, CNGgust. J. Biol. Chem. 272, 22,623-22,629.
35. Nawy S. and Jahr C. E. (1990) Suppression by glutamate of cGMP-activated conductance in retinal bipolar cells. Nature 346, 269-271.
36. Oda Y., Timpe L. C., McKenzie R. C., Sauder, D. N., Largman C., and Mauro T. (1997) Alternatively spliced forms of the cGMP-gated channel in human keratinocytes. FEBS Lett. 414, 140-145.
37. 3 domain of N-src identifies a new brain specific ion channel protein, with hemology with Eag and cyclic nucleotide-gated channels. Proc. Natl. Acad. Sci. USA 94, 14,815-14,820.
38. Scott S.-P., Harrison R. W., Weber I. T., and Tanaka J. C. (1996) Predicted ligand interactions for 3′,5′-cyclic nucleotide-gated channel binding sites: comparison of retina and olfactory binding site models. Protein Engineer. 9, 333-344.
39. Shabb J. B. and Corbin J. D. (1992) Cyclic nucleotide-binding domains in protein having diverse functions. J. Biol. Chem. 267, 5723-5726.
40. Shiells R. A. and Falk G. (1990) Glutamate receptors of rod bipolar cells are linked to a cyclic GMP cascade via a G-protein. Proc. R. Soc. Lond [Biol]. 242, 91-94.
41. Thompson S. H. (1997) Cyclic GMP-gated channels in a sympathetic neuron cell line. J. Gen. Physiol. 110, 155-164.
42. Varnum M. D., Black K. D., and Zagotta W. N. (1995) Molecular mechanism for ligand discrimination of cyclic nucleotide-gated channel. Neuron 15, 619-625.
43. 2-etheno substituted cGMP analogues as probes of the cGMP-binding site. Biochemistry 35, 16,815-16,823.
44. Wei J.-Y., Cohen E. D., and Barnstable C. J. (1997a) Direct blockade of both cloned rat rod photoreceptor cyclic nucleotide-gated non-selective cation (CNG) channel α-subunit and native CNG channels from Xenopus rod outer segments by H-8, a non-specific cyclic nucleotide-dependent protein kinase inhibitor. Neurosci. Lett. 233, 37-40.
45. Wei J.-Y., Samanta Roy D., Cohen E. D., and Barnstable C. J. (1997b) Cyclic nucleotide-gated channels and protein kinases can act together to increase excitatory transmission at cortical synapses. Soc. Neurosci. Abstr. 23, 1267.
46. Wei J.-Y., Samanta Roy D., Leconte L., and Barnstable C. J. (1998) Molecular and pharmacological analysis of cylic nucleotide-gated channel function in central nervous system. Prog. Neurobiol., in press.
47. Weyand I., Godde M., Frings S., Weiner J., Muller F., Altenhofen W., Hatt H., and Kaupp U. B. (1994) Cloning and functional expression of a cyclic nucleotide-gated channel from mammalian sperm. Nature 368, 859-863.
48. Wilson R., Ainscough R., Anderson K., Baynes C., Berks M., Bonfield J., Burtin J., Connell M., Copsey T., and Cooper J. (1994) 2.2 MB of contiguous nucleotide sequence from chromosome in of C. elegans. Nature 368, 32-38.
49. Yau K.-W. (1994) Cyclic nucleotide-gated channels: an expanding new family of ion channels. Proc. Natl. Acad. Sci. USA 91, 3481-3483.
50. Zagotta W. N. and Siegelbaum S. A. (1996) Structure and function of cyclic nucleotide-gated channels. Annu. Rev. Neurosci. 19, 235-263.
51. Zimmermann A. L., Yamanaka G., Eckstein F., Baylor D. A., and Stryer L. (1985) Interaction of hydrolysis-resistant analogs of cyclic GMP with the phosphodiesterase and light-sensitive channel of retinal rod outer segments. Proc. Natl. Acad. Sci. USA 82, 8813-8817.
52. Zufall F., Shepherd G. M., and Barnstable C. J. (1997) Cyclic nucleotide-gated channels as regulators of CNS development and plasticity. Curr. Opinion Neurobiol. 7, 404-412.